메뉴 건너뛰기




Volumn 104, Issue 9, 2011, Pages 1459-1471

Co-overexpression of Bag-1 and heat shock protein 70 in human epidermal squamous cell carcinoma: Bag-1-mediated resistance to 5-fluorouracil-induced apoptosis

Author keywords

5 fluorouracil; apoptosis; Bag 1; heat shock protein 70; immunohistochemistry; skin

Indexed keywords

BAG 1 PROTEIN; FLUOROURACIL; HEAT SHOCK PROTEIN 70;

EID: 79955419246     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2011.111     Document Type: Article
Times cited : (15)

References (58)
  • 1
    • 0037195907 scopus 로고    scopus 로고
    • Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome
    • DOI 10.1074/jbc.M204196200
    • Alberti S, Demand J, Esser C, Emmerich N, Schild H, Höhfeld J (2002) Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome. J Biol Chem 277: 45920-45927 (Pubitemid 35417574)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.48 , pp. 45920-45927
    • Alberti, S.1    Demand, J.2    Esser, C.3    Emmerich, N.4    Schild, H.5    Hohfeld, J.6
  • 3
    • 22144490885 scopus 로고    scopus 로고
    • Ultraviolet radiation-induced apoptosis in keratinocytes: On the role of cytosolic factors
    • DOI 10.1016/j.bbcan.2005.04.001, PII S0304419X05000089
    • Assefa Z, Van Laethem A, Garmyn M, Agostinis P (2005) Ultraviolet radiation-induced apoptosis in keratinocytes: on the role of cytosolic factors. Biochim Biophys Acta 1755: 90-106 (Pubitemid 40982560)
    • (2005) Biochimica et Biophysica Acta - Reviews on Cancer , vol.1755 , Issue.2 , pp. 90-106
    • Assefa, Z.1    Van Laethem, A.2    Garmyn, M.3    Agostinis, P.4
  • 6
    • 21744434825 scopus 로고    scopus 로고
    • UV-induced skin cancer: Similarities - Variations
    • DOI 10.1111/j.1610-0387.2005.05037.x
    • Boukamp P (2005) UV-induced skin cancer: similarities - variations. J Dtsch Dermatol Ges 3: 493-503 (Pubitemid 40942631)
    • (2005) JDDG - Journal of the German Society of Dermatology , vol.3 , Issue.7 , pp. 493-503
    • Boukamp, P.1
  • 8
    • 70349443284 scopus 로고    scopus 로고
    • When mutants gain new powers: News from the mutant p53 field
    • Brosh R, Rotter V (2009) When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer 9: 701-713
    • (2009) Nat Rev Cancer , vol.9 , pp. 701-713
    • Brosh, R.1    Rotter, V.2
  • 10
    • 84880324406 scopus 로고    scopus 로고
    • Cancer Research UK Accessed 2010
    • Cancer Research UK. Skin cancer - UK incidence statistics. http://info.cancer researchuk.org/cancerstats/types/skin/incidence/ (Accessed 2010)
    • Skin Cancer - UK Incidence Statistics
  • 11
    • 0037057339 scopus 로고    scopus 로고
    • Distinct BAG-1 isoforms have different anti-apoptotic functions in BAG-1-transfected C33A human cervical carcinoma cell line
    • DOI 10.1038/sj.onc.1205845
    • Chen J, Xiong J, Liu H, Chernenko G, Tang SC (2002) Distinct BAG-1 isoforms have different anti-apoptotic functions in BAG-1-transfected C33A human cervical carcinoma cell line. Oncogene 21: 7050-7059 (Pubitemid 35252979)
    • (2002) Oncogene , vol.21 , Issue.46 , pp. 7050-7059
    • Chen, J.1    Xiong, J.2    Liu, H.3    Chernenko, G.4    Tang, S.-C.5
  • 12
    • 0030893637 scopus 로고    scopus 로고
    • Role of Bag-1 in the survival and proliferation of the cytokine- dependent lymphocyte lines, Ba/F3 and Nb2
    • Clevenger CV, Thickman K, Ngo W, Chang WP, Takayama S, Reed JC (1997) Role of Bag-1 in the survival and proliferation of the cytokine-dependent lymphocyte lines, Ba/F3 and Nb2. Mol Endocrinol 11: 608-618 (Pubitemid 27193796)
    • (1997) Molecular Endocrinology , vol.11 , Issue.5 , pp. 608-618
    • Clevenger, C.V.1    Thickman, K.2    Ngo, W.3    Chang, W.-P.4    Takayama, S.5    Reed, J.C.6
  • 13
    • 0033120746 scopus 로고    scopus 로고
    • Altered expression of bcl-2 family member proteins in nonmelanoma skin cancer
    • DOI 10.1002/(SICI)1097-0142(19990401)85:7<1514::AID-CNCR12>3.0. CO;2-Q
    • Delehedde M, Cho SH, Sarkiss M, Brisbay S, Davies M, El-Naggar AK, McDonnell TJ (1999) Altered expression of bcl-2 family member proteins in nonmelanoma skin cancer. Cancer 85: 1514-1522 (Pubitemid 29152823)
    • (1999) Cancer , vol.85 , Issue.7 , pp. 1514-1522
    • Delehedde, M.1    Cho, S.H.2    Sarkiss, M.3    Brisbay, S.4    Davies, M.5    El-Naggar, A.K.6    McDonnell, T.J.7
  • 14
    • 0342803660 scopus 로고    scopus 로고
    • 3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: Possible implications for prevention and therapy
    • D́?az GD, Paraskeva C, Thomas MG, Binderup L, Hague A (2000) Apoptosis is induced by the active metabolite of vitamin D3 and its analogue EB1089 in colorectal adenoma and carcinoma cells: possible implications for prevention and therapy. Cancer Res 60: 2304-2312 (Pubitemid 30225198)
    • (2000) Cancer Research , vol.60 , Issue.8 , pp. 2304-2312
    • Diaz, G.D.1    Paraskeva, C.2    Thomas, M.G.3    Binderup, L.4    Hague, A.5
  • 15
    • 0028978505 scopus 로고
    • Cellular immortality: A late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss
    • Edington KG, Loughran OP, Berry IJ, Parkinson EK (1995) Cellular immortality: a late event in the progression of human squamous cell carcinoma of the head and neck associated with p53 alteration and a high frequency of allele loss. Mol Carcinog 13: 254-265
    • (1995) Mol Carcinog , vol.13 , pp. 254-265
    • Edington, K.G.1    Loughran, O.P.2    Berry, I.J.3    Parkinson, E.K.4
  • 17
    • 5044239253 scopus 로고    scopus 로고
    • Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage
    • DOI 10.1002/path.1630
    • Hague A, Eveson JW, MacFarlane M, Huntley S, Janghra N, Thavaraj S (2004) Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage. J Pathol 204: 175-182 (Pubitemid 39335291)
    • (2004) Journal of Pathology , vol.204 , Issue.2 , pp. 175-182
    • Hague, A.1    Eveson, J.W.2    MacFarlane, M.3    Huntley, S.4    Janghra, N.5    Thavaraj, S.6
  • 18
    • 0027485599 scopus 로고
    • Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: Implications for the possible role of dietary fibre in the prevention of large-bowel cancer
    • DOI 10.1002/ijc.2910550329
    • Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D, Paraskeva C (1993) Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. Int J Cancer 55: 498-505 (Pubitemid 23300605)
    • (1993) International Journal of Cancer , vol.55 , Issue.3 , pp. 498-505
    • Hague, A.1    Manning, A.M.2    Hanlon, K.A.3    Huschtscha, L.I.4    Hart, D.5    Paraskeva, C.6
  • 19
    • 0036239278 scopus 로고    scopus 로고
    • Deregulated Bag-1 protein expression in human oral squamous cell carcinomas and lymph node metastases
    • DOI 10.1002/path.1076
    • Hague A, Packham G, Huntley S, Shefford K, Eveson JW (2002) Deregulated Bag-1 protein expression in human oral squamous cell carcinomas and lymph node metastases. J Pathol 197: 60-71 (Pubitemid 34450165)
    • (2002) Journal of Pathology , vol.197 , Issue.1 , pp. 60-71
    • Hague, A.1    Packham, G.2    Huntley, S.3    Shefford, K.4    Eveson, J.W.5
  • 20
    • 0344039806 scopus 로고    scopus 로고
    • GrpE-like regulation of the Hsc70 chaperone by the anti-apoptotic protein BAG-1
    • DOI 10.1093/emboj/16.20.6209
    • Höhfeld J, Jentsch S (1997) GrpE-like regulation of the hsc70 chaperone by the anti-apoptotic protein BAG-1. EMBO J 16: 6209-6216 (Pubitemid 27458341)
    • (1997) EMBO Journal , vol.16 , Issue.20 , pp. 6209-6216
    • Hohfeld, J.1    Jentsch, S.2
  • 21
    • 0038641980 scopus 로고    scopus 로고
    • Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions
    • DOI 10.1128/MCB.23.10.3477-3486.2003
    • Hung WJ, Roberson RS, Taft J, Wu DY (2003) Human BAG-1 proteins bind to the cellular stress response protein GADD34 and interfere with GADD34 functions. Mol Cell Biol 23: 3477-3486 (Pubitemid 36539180)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.10 , pp. 3477-3486
    • Hung, W.J.1    Roberson, R.S.2    Taft, J.3    Wu, D.Y.4
  • 22
    • 7444224713 scopus 로고    scopus 로고
    • Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions
    • DOI 10.1111/j.0303-6987.2004.00244.x
    • Hussein MR, Al-Badaiwy ZH, Guirguis MN (2004) Analysis of p53 and bcl-2 protein expression in the non-tumorigenic, pretumorigenic, and tumorigenic keratinocytic hyperproliferative lesions. J Cutan Pathol 31: 643-651 (Pubitemid 39440844)
    • (2004) Journal of Cutaneous Pathology , vol.31 , Issue.10 , pp. 643-651
    • Hussein, M.R.1    Al-Badaiwy, Z.H.2    Guirguis, M.N.3
  • 24
    • 0038668000 scopus 로고    scopus 로고
    • Escaping cell death: Survival proteins in cancer
    • DOI 10.1006/excr.1999.4455
    • Jäättelä M (1999) Escaping cell death: survival proteins in cancer. Exp Cell Res 248: 30-43 (Pubitemid 29393927)
    • (1999) Experimental Cell Research , vol.248 , Issue.1 , pp. 30-43
    • Jaattela, M.1
  • 25
    • 0031763046 scopus 로고    scopus 로고
    • Expression of 70-kDa heat shock protein in oral lesions: Marker of biological stress or pathogenicity
    • DOI 10.1016/S1368-8375(98)00064-5, PII S1368837598000645
    • Kaur J, Srivastava A, Ralhan R (1998) Expression of 70-kDa heat shock protein in oral lesions: marker of biological stress or pathogenicity. Oral Oncol 34: 496-501 (Pubitemid 28546864)
    • (1998) Oral Oncology , vol.34 , Issue.6 , pp. 496-501
    • Kaur, J.1    Srivastava, A.2    Ralhan, R.3
  • 27
    • 0033795921 scopus 로고    scopus 로고
    • Incidence of skin cancer in 5356 patients following organ transplantation
    • Lindelöf B, Sigurgeirsson B, Gäbel H, Stern RS (2000) Incidence of skin cancer in 5356 patients following organ transplantation. Br J Dermatol 143: 513-519
    • (2000) Br J Dermatol , vol.143 , pp. 513-519
    • Lindelöf, B.1    Sigurgeirsson, B.2    Gäbel, H.3    Stern, R.S.4
  • 29
    • 0039172708 scopus 로고    scopus 로고
    • The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome
    • DOI 10.1074/jbc.275.7.4613
    • Lüders J, Demand J, Höhfeld J (2000) The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome. J Biol Chem 275: 4613-4617 (Pubitemid 30108845)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.7 , pp. 4613-4617
    • Luders, J.1    Demand, J.2    Hohfeld, J.3
  • 31
    • 0032525309 scopus 로고    scopus 로고
    • P53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: Suppression by BAG-1
    • Matsuzawa S, Takayama S, Froesch BA, Zapata JM, Reed JC (1998) p53-inducible human homologue of Drosophila seven in absentia (Siah) inhibits cell growth: suppression by BAG-1. EMBO J 15: 2736-2747
    • (1998) EMBO J , vol.15 , pp. 2736-2747
    • Matsuzawa, S.1    Takayama, S.2    Froesch, B.A.3    Zapata, J.M.4    Reed, J.C.5
  • 33
    • 72449156634 scopus 로고    scopus 로고
    • Clinical applications for topical 5-fluorouracil in the treatment of dermatological disorders
    • Moore AY (2009) Clinical applications for topical 5-fluorouracil in the treatment of dermatological disorders. J Dermatolog Treat 20: 328-335
    • (2009) J Dermatolog Treat , vol.20 , pp. 328-335
    • Moore, A.Y.1
  • 35
    • 0031466639 scopus 로고    scopus 로고
    • Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation
    • Packham G, Brimmell M, Cleveland JL (1997) Mammalian cells express two differently localized Bag-1 isoforms generated by alternative translation initiation. Biochem J 328(Part 3): 807-813 (Pubitemid 28005779)
    • (1997) Biochemical Journal , vol.328 , Issue.3 , pp. 807-813
    • Packham, G.1    Brimmell, M.2    Cleveland, J.L.3
  • 37
    • 0034030578 scopus 로고    scopus 로고
    • Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis
    • DOI 10.1034/j.1600-0625.2000.009002104.x
    • Proby CM, Purdie KJ, Sexton CJ, Purkis P, Navsaria HA, Stables JN, Leigh IM (2000) Spontaneous keratinocyte cell lines representing early and advanced stages of malignant transformation of the epidermis. Exp Dermatol 9: 104-117 (Pubitemid 30192708)
    • (2000) Experimental Dermatology , vol.9 , Issue.2 , pp. 104-117
    • Proby, C.M.1    Purdie, K.J.2    Sexton, C.J.3    Purkis, P.4    Navsaria, H.A.5    Stables, J.N.6    Leigh, I.M.7
  • 38
    • 0019471387 scopus 로고
    • Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas
    • Rheinwald JG, Beckett MA (1981) Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultures from human squamous cell carcinomas. Cancer Res 41: 1657-1663 (Pubitemid 11114553)
    • (1981) Cancer Research , vol.41 , Issue.5 , pp. 1657-1663
    • Rheinwald, J.G.1    Beckett, M.A.2
  • 39
    • 70349327819 scopus 로고    scopus 로고
    • UV-induced squamous cell carcinoma - A role for antiapoptotic signalling pathways
    • Rodust PM, Stockfleth E, Ulrich C, Leverkus M, Eberle J (2009) UV-induced squamous cell carcinoma - a role for antiapoptotic signalling pathways. Br J Dermatol 161(Suppl 3): 107-115
    • (2009) Br J Dermatol , vol.161 , Issue.SUPPL. 3 , pp. 107-115
    • Rodust, P.M.1    Stockfleth, E.2    Ulrich, C.3    Leverkus, M.4    Eberle, J.5
  • 40
  • 43
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S, Sato T, Krajewski S, Kochel K, Irie S, Millan JA, Reed JC (1995) Cloning and functional analysis of BAG-1: a novel Bcl-2-binding protein with anti-cell death activity. Cell 80: 279-284
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3    Kochel, K.4    Irie, S.5    Millan, J.A.6    Reed, J.C.7
  • 44
    • 1842430149 scopus 로고    scopus 로고
    • BAG-1 expression correlates with Bcl-2, p53, differentiation, estrogen and progesterone receptors in invasive breast carcinoma
    • DOI 10.1023/B:BREA.0000019951.32001.93
    • Tang SC, Beck J, Murphy S, Chernenko G, Robb D, Watson P, Khalifa M (2004) BAG-1 expression correlates with Bcl-2, p53, differentiation, estrogen and progesterone receptors in invasive breast carcinoma. Breast Cancer Res Treat 84: 203-213 (Pubitemid 38445370)
    • (2004) Breast Cancer Research and Treatment , vol.84 , Issue.3 , pp. 203-213
    • Tang, S.-C.1    Beck, J.2    Murphy, S.3    Chernenko, G.4    Robb, D.5    Watson, P.6    Khalifa, M.7
  • 45
    • 2442658924 scopus 로고    scopus 로고
    • BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome
    • DOI 10.1074/jbc.M400399200
    • Townsend PA, Cutress RI, Carroll CJ, Lawrence KM, Scarabelli TM, Packham G, Stephanou A, Latchman DS (2004) BAG-1 proteins protect cardiac myocytes from simulated ischemia/reperfusion-induced apoptosis via an alternate mechanism of cell survival independent of the proteasome. J Biol Chem 279: 20723-20728 (Pubitemid 38656469)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.20 , pp. 20723-20728
    • Townsend, P.A.1    Cutress, R.I.2    Carroll, C.J.3    Lawrence, K.M.4    Scarabelli, T.M.5    Packham, G.6    Stephanou, A.7    Latchman, D.S.8
  • 47
    • 0042173040 scopus 로고    scopus 로고
    • BAG-1 prevents stress-induced long-term growth inhibition in breast cancer cells via a chaperone-dependent pathway
    • Townsend PA, Cutress RI, Sharp A, Brimmell M, Packham G (2003b) BAG-1 prevents stress-induced long-term growth inhibition in breast cancer cells via a chaperone-dependent pathway. Cancer Res 63: 4150-4157 (Pubitemid 36917940)
    • (2003) Cancer Research , vol.63 , Issue.14 , pp. 4150-4157
    • Townsend, P.A.1    Cutress, R.I.2    Sharp, A.3    Brimmell, M.4    Packham, G.5
  • 49
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1
    • Wang HG, Takayama S, Rapp UR, Reed JC (1996) Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci USA 93: 7063-7068
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7063-7068
    • Wang, H.G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4
  • 51
    • 58549105080 scopus 로고    scopus 로고
    • Bag-1 proteins in oral squamous cell carcinoma
    • Wood J, Lee SS, Hague A (2009) Bag-1 proteins in oral squamous cell carcinoma. Oral Oncol 45: 94-102
    • (2009) Oral Oncol , vol.45 , pp. 94-102
    • Wood, J.1    Lee, S.S.2    Hague, A.3
  • 52
    • 4944236708 scopus 로고    scopus 로고
    • Bag-1 expression as a prognostic factor in tongue squamous cell carcinomas
    • DOI 10.1097/00005537-200410000-00021
    • Xie X, Clausen OP, Boysen M (2004) Bag-1 expression as a prognostic factor in tongue squamous cell carcinomas. Laryngoscope 114: 1785-1790 (Pubitemid 39332256)
    • (2004) Laryngoscope , vol.114 , Issue.10 , pp. 1785-1790
    • Xie, X.1    Clausen, O.P.F.2    Boysen, M.3
  • 54
    • 0032572715 scopus 로고    scopus 로고
    • Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells
    • Yang X, Chernenko G, Hao Y, Ding Z, Pater MM, Pater A, Tang SC (1998) Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells. Oncogene 17: 981-989 (Pubitemid 28425408)
    • (1998) Oncogene , vol.17 , Issue.8 , pp. 981-989
    • Yang, X.1    Chernenko, G.2    Hao, Y.3    Ding, Z.4    Pater, M.M.5    Pater, A.6    Tang, S.-C.7
  • 55
    • 0033549844 scopus 로고    scopus 로고
    • Cloning and characterization of the human BAG-1 gene promoter: Upregulation by tumor-derived p53 mutants
    • DOI 10.1038/sj.onc.1202843
    • Yang X, Pater A, Tang SC (1999) Cloning and characterization of the human BAG-1 gene promoter: upregulation by tumor-derived p53 mutants. Oncogene 18: 4546-4553 (Pubitemid 29405886)
    • (1999) Oncogene , vol.18 , Issue.32 , pp. 4546-4553
    • Yang, X.1    Pater, A.2    Tang, S.-C.3
  • 56
    • 0030766734 scopus 로고    scopus 로고
    • Mammalian protein RAP46: An interaction partner and modulator of 70 kDa heat shock proteins
    • DOI 10.1093/emboj/16.18.5483
    • Zeiner M, Gebauer M, Gehring U (1997) Mammalian protein RAP46: an interaction partner and modulator of 70 kDa heat shock proteins. EMBO J 16: 5483-5490 (Pubitemid 27399840)
    • (1997) EMBO Journal , vol.16 , Issue.18 , pp. 5483-5490
    • Zeiner, M.1    Gebauer, M.2    Gehring, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.