Somatic mutagenesis with a Sleeping Beauty transposon system leads to solid tumor formation in zebrafish

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  McGrail, Maura ^a   Hatler, Julia M ^b   Kuang, Xianyan ^a   Liao, Hsin Kai ^a   Nannapaneni, Kishore ^c   Watt, Kristin E Noack ^a   Uhl, Juli D ^a   Largaespada, David A ^b   Vollbrecht, Erik ^a   Scheetz, Todd E ^c   Dupuy, Adam J ^d   Hostetter, Jesse M ^a   Essner, Jeffrey J ^a  

^a IOWA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; DNA; MESSENGER RNA; RNA; TRANSPOSASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRD2 GENE; CARCINOGENESIS; CIRBP GENE; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DISEASE MODEL; FGF8 GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC CONSERVATION; HEXIM1 GENE; MALIGNANT NEOPLASTIC DISEASE; MAP2K5 GENE; MMP14 GENE; MOLECULAR CLONING; MUTAGENESIS; NCOA2 GENE; NONHUMAN; ONCOGENE; POLYMERASE CHAIN REACTION; PROMOTER REGION; SLC30A5 GENE; SOMATIC MUTAGENESIS; SOX4 GENE; SOX5 GENE; TRANSGENE; TRANSGENICS; TRANSPOSON; ZEBRA FISH; ANIMAL; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; TRANSGENIC ANIMAL;

CYPRINIDAE; DANIO RERIO; VERTEBRATA;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; DNA; DNA TRANSPOSABLE ELEMENTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; POLYMERASE CHAIN REACTION; ZEBRAFISH;

EID: 79955378909     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018826     Document Type: Article

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