A functional type I interferon pathway drives resistance to cornea herpes simplex virus type 1 infection by recruitment of leukocytes

Journal of Biomedical Research

Volumn 25, Issue 2, 2011, Pages 111-119

  Conrady, Christopher D ^a   Jones, Heather ^a   Zheng, Min ^a   Carr, Daniel J J ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Cornea; Herpes simplex virus type 1; Leukocytes; Ocular immunology; Type I interferon; Viral infection

Indexed keywords

ALPHA INTERFERON; ALPHA INTERFERON RECEPTOR;

ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CORNEA EPITHELIUM; CYTOKINE PRODUCTION; EPITHELIUM CELL; HERPES SIMPLEX KERATITIS; HERPES SIMPLEX VIRUS 1; INFECTION SENSITIVITY; LYMPHATIC DRAINAGE; MALE; MOUSE; NERVOUS SYSTEM; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; VIRUS PLAQUE; VIRUS RESISTANCE; WILD TYPE;

EID: 79955157073     PISSN: 16748301     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1674-8301(11)60014-6     Document Type: Article

References (54)

1. Whitley RJ, Roizman B. Herpes Simplex Viruses. 3rd edition. Washington: DD Richman, RJ Whitley, and F.G. Hayden, 2009:409-49.
2. Honess RW, Roizman B Regulation of herpes virus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J Virol 1974, 14:8-19.
3. Halford WP, Weisand C, Grace J, Soboleski M, Carr DJJ, Balliet JW, et al. ICP0 antagonizes Stat I-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virology J 2006, 3:44.
4. Leib DA, Machalek MA, Williams BR, Silverman RH, Virgin HW Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proc Natl Acad Sci USA 2000, 97:6097-6101.
5. Nakayama Y, Plisch EH, Sullivan J, Thomas C, Czuprynski CJ, Williams BRG, Suresh M Role of PKR and type I IFNs in viral control during primary and secondary infection. PLoS Pathogens 2010, 6:e1000966.
6. Poppers J, Mulvey M, Khoo D, Mohr I Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein. J Virol 2000, 74:11215-11221.
7. Chou J, Chen JJ, Gross M, Roizman B Association of a M(r) 90,000 phosphoprotein with protein kinase PKR in cells exhibiting enhanced phosphorylation of translation initiation factor eIF-2 alpha and premature shutoff of protein synthesis after infection with gamma 134.5-mutants of herpes simplex virus 1. Proc Natl Acad Sci USA 1995, 92:10516-10520.
8. Melchjorsen J, Siren J, Julkunen I, Paludan SR, Matikainen S Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3. J Gen Virol 2006, 87:1099-1108.
9. Zhou A, Hassel BA, Silverman RH Expression cloning of 2-5-A-dependnet RNase: a uniquely regulated mediator of interferon action. Cell 1993, 72:753-765.
10. Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, et al. Interferon action and apoptosis are detective in mice devoid of 2′, 5′-oligoadenylate-dependent RNase L. EMBO J 1997, 16:6355-6363.
11. Samuel CE Antiviral actions of interferons. Clin Microbiol Rev 2001, 14:778-809.
12. Mossman KL, Ashkar AA Herpesvirus and the innate immune response. Viral Immunol 2005, 18:267-281.
13. Von Hoegen P Synergistic role of type I interferons in the induction of protective cytotoxic T lymphocytes. Immunol Lett 1995, 47:157-162.
14. Marrack P, Kappler J, Mitchell T Type I interferons keep activated T cells alive. J Exp Med 1999, 189:521-529.
15. Kolumam GA, Thomas S, Thompson LJ, Sprent J, K Murali-Krishna Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection. J Exp Med 2005, 202:637-650.
16. Xiao Z, Casey KA, Jameson SC, Curtsinger JM, Mescher MF Programming for CD8 T cell memory development requires IL-12 and type I IFN. J Immunol 2009, 182:2786-2794.
17. + T cells altering their response to antigen. J Immunol 2009, 183:2915-2920.
18. Conrady CD, Thapa M, Wuest T, Carr DJJ Loss of mandibular lymph node integrity is associated with an increase in sensitivity to HSV-1 infection in CD118-deficient mice. J Immunol 2009, 182:3678-3687.
19. Garvey TL, Dyer KD, Ellis JA, Bonville CA, Foster B, Prussin C, et al. Inflammatory responses to pneumovirus infection in IFN-αβ gene-deleted mice. J Immunol 2005, 175:4735-4744.
20. Halford WP, Gebhardt BM, Carr DJJ Mechanisms of herpes simplex virus type 1 reactivation. J Virol 1996, 70:5051-5060.
21. Wuest T, Carr DJJ Dysregulation of CXCR3 signaling due to CXCL10 deficiency impairs the anti-viral response to HSV-1 infection. J Immunol 2008, 181:7985-7993. PubMed.
22. Hendricks RL, Weber PC, Taylor JL, Koumbis A, Tumpey TM, Glorioso JC Endogenously produced interferon α protects mice from herpes simplex type 1 corneal disease. J Gen Virol 1991, 72:1601-1610. PubMed.
23. Halford WP, Veress LA, Gebhardt BM, Carr DJJ Innate and acquired immunity to herpes simplex virus type 1. Virology 1997, 236:328-337. PubMed.
24. Austin BA, James C, Silverman RH, Carr DJJ Critical role for the oligoadenylate synthetase/RNase L pathway in response to IFN-β during acute ocular herpes simplex virus type 1 infection. J Immunol 2005, 175:1100-1106. PubMed.
25. Topp KS, Meade LB, JH LeVail Microtubule polarity in the peripheral processes of trigeminal ganglion cells: relevance for the retrograde transport of herpes simplex virus. J Neurosci 1994, 14:318-325. PubMed.
26. Vollstedt S, Arnold S, Schwerdel C, Franchini M, Alber G, Di Santo JP, et al. Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1. J Virol 2004, 78:3846-3850. PubMed.
27. Kamphuis E, Junt T, Waibler Z, Forster R, Kalinke U Type I interferons directly regulate lymphocyte recirculation and cause transient blood lymphopenia. Blood 2006, 108:3253-3261. PubMed.
28. Marshall HD, Prince AL, LJ Berg, RM Welsh IFN-αβ and self-MHC divert CD8 T cells into a distinct differentiation pathway characterized by rapid acquisition of effector functions. J Immunol 2010, 185:1419-1428. PubMed.
29. Andrews DM, Estcourt M, Andoniou CE, Wikstrom ME, Khong A, Voigt V, et al. Innate immunity defines the capacity of antiviral T cells to limit persistent infection. J Exp Med 2010, 207:1333-1343. PubMed.
30. Y-S Su, X-T Yan, JE Oakes, RN Lausch Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection. J Virol 1996, 70:1277-1281. PubMed.
31. Tumpey TM, Cheng H, X-T , JE Oakes, RN Lausch Chemokine synthesis in the HSV-1-infected cornea and its suppression by interleukin-10. J Leukoc Biol 1998, 63:486-492. PubMed.
32. Carr DJJ, Tomanek L Herpes simplex virus and the chemokines that mediate the inflammation. Curr Top Microbiol Immunol 2006, 303:47-65. PubMed.
33. Carr DJJ, Chodosh J, Ash J, Carr DJJ Effect of anti-CXCL10 monoclonal antibody on herpes simplex virus type1 keratitis and retinal infection. J Virol 2003, 77:10037-10046. PubMed.
34. Muller M, Steinhoff U, Reis LFL, Hemmi S, Pavlovic J, Zinkernagel RM, et al. Functional role of type I and type II interferons in antiviral defense. Science 1994, 264:1918-1921. PubMed.
35. Hwang SY, Hertzog PJ, Holland KA, Sumarsono SH, Tymms MJ, Hamilton JA, et al. A null mutation in the gene encoding a type I interferon receptor component eliminates antiproliferative and antiviral responses to interferons α and β and alters macrophage responses. Proc Natl Acad Sci USA 1995, 92:11284-11288.
36. Luker GD, Prior JL, Song J, Pica CM, Leib DA Bioluminescence imaging reveals systemic dissemination of herpes simplex virus type 1 in the absence of interferon receptors. J Virol 2003, 77:11082-11093. PubMed.
37. Cucak H, Yrlid U, Reizis B, Kalinke U, B Johansson-Lindbom Type I interferon signaling in dendritic cells stimulates the development of lymph-node-resident T follicular helper cells. Immun 2009, 31:491-501. PubMed.
38. Krawczyk A, Krauss J, AM Eis-Hubinger, MP Daumer, R Schwarzenbacher, U Dittmer, et al. Impact of valency of a glycoprotein B specific monoclonal antibody on neutralization of herpes simplex virus. J Virol 2010, in press.
39. Noisakran S, Campbell IL, Carr DJJ Ectopic expression of DNA encoding IFN-α1 in the cornea protects mice from herpes simplex virus type-1-induced encephalitis. J Immunol 1999, 162:4184-4190. PubMed.
40. Cui B, Carr DJJ A plasmid construct encoding murine interferon beta antagonizes the replication of herpes simplex virus type I in vitro and in vivo. J Neuroimmunol 2000, 108:92-102. PubMed.
41. Bron AJ, Tripathi DM, Tripathi BJ Wolff's anatomy of the eye and orbit 1997, Chapman & Hall Medical, London.
42. Hamrah P, Zhang Q, Liu Y, Dana MR Novel characterization of MHC class II-negative population of resident corneal Langerhans cell-type dendritic cells. Invest Ophthalmol Vis Sci 2002, 43:639-646.
43. CS Brissette-Storkus, SM Reynolds, AJ Lepisto, RL Hendricks Identification of a novel macrophage population in the normal mouse corneal stroma. Invest Ophthalmol Vis Sci 2002, 43:2264-2271.
44. Klareskog L, Rorsum U, Malmnas T, Rask L, Peterson PA Expression of Ia antigen-like molecules on cells in the corneal epithelium. Invest Ophthalmol Vis Sci 1979, 18:310-313.
45. Dufour JH, Dziejman M, Lu MT, Leung JH, Lane TE, Luster AD IFN-γ-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking. J Immunol 2002, 168:3195-3204.
46. Wuest T, Austin BA, Uematsu S, Thapa M, Akira S, Carr DJJ Intact TLR 9 and type I interferon signaling pathways are required to augment HSV-1 induced corneal CXCL9 and CXCL10. J Neuroimmunol 2006, 179:46-52.
47. Wuest T, Farber J, Luster A, Carr DJJ CD4+ T cell migration into the cornea is reduced in CXCL9 deficient but not CXCL10 deficient mice following herpes simplex virus type 1 infection. Cell Immunol 2006, 243:83-89.
48. Wood LD, Richmond A Constitutive and cytokine-induced expression of the melanoma growth stimulatory activity/GRO alpha gene requires both NF-kappaB and novel constitutive factors. J Biol Chem 1995, 270:30619-30626.
49. Bonneau RH, Jennings SR Modulation of acute and latent herpes simplex virus infection in C57BL/6 mice by adoptive transfer of immune lymphocytes with cytolytic activity. J Virol 1989, 63:1480-1484.
50. Rajasagi NK, Kassim SH, Kollias CM, Zhao X, Chervenak R, Jennings SR CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1. J Virol 2009, 83:5256-5268.
51. Metcalf JF, Whitley RJ Protective immunity against herpetic ocular disease in an outbred mouse model. Curr Eye Res 1987, 6:167-171.
52. Hendricks RL, Tumpey TM Contribution of virus and immune factors to herpes simplex virus type I-induced corneal pathology. Invest Ophthalmol Vis Sci 1990, 31:1929-1939.
53. Pepose JS Herpes simplex keratitis: Role of viral infection versus immune response. Surv Ophthalmol 1991, 35:345-352.
54. Niemialtowski MG, Rouse BT Phenotypic and functional studies on ocular T cells during herpetic infections of the eye. J Immunol 1992, 148:1864-1870.