-
1
-
-
40549140724
-
Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity
-
Baig I., Perez M., Brana A.F., Gomathinayagam R., Damodaran C., Salas J.A., Mendez C., Rohr J. Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity. J. Nat. Prod. 2008, 71:199-207.
-
(2008)
J. Nat. Prod.
, vol.71
, pp. 199-207
-
-
Baig, I.1
Perez, M.2
Brana, A.F.3
Gomathinayagam, R.4
Damodaran, C.5
Salas, J.A.6
Mendez, C.7
Rohr, J.8
-
2
-
-
33845709126
-
Molecular engineering approaches to peptide, polyketide and other antibiotics
-
Baltz R.H. Molecular engineering approaches to peptide, polyketide and other antibiotics. Nat. Biotechnol. 2006, 24:1533-1540.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1533-1540
-
-
Baltz, R.H.1
-
3
-
-
0020598415
-
Polyoxin D inhibits growth of zoopathogenic fungi
-
Becker J.M., Covert N.L., Shenbagamurthi P., Steinfeld A.S., Naider F. Polyoxin D inhibits growth of zoopathogenic fungi. Antimicrob. Agents Chemother. 1983, 23:926-929.
-
(1983)
Antimicrob. Agents Chemother.
, vol.23
, pp. 926-929
-
-
Becker, J.M.1
Covert, N.L.2
Shenbagamurthi, P.3
Steinfeld, A.S.4
Naider, F.5
-
4
-
-
0021969704
-
Metabolic products of microorganisms. 228. New nikkomycins produced by mutants of Streptomyces tendae
-
Bormann C., Huhn W., Zahner H., Rathmann R., Hahn H., Konig W.A. Metabolic products of microorganisms. 228. New nikkomycins produced by mutants of Streptomyces tendae. J. Antibiot. 1985, 38:9-16.
-
(1985)
J. Antibiot.
, vol.38
, pp. 9-16
-
-
Bormann, C.1
Huhn, W.2
Zahner, H.3
Rathmann, R.4
Hahn, H.5
Konig, W.A.6
-
5
-
-
0032816588
-
Novel nikkomycins Lx and Lz produced by genetically engineered Streptomyces tendae Tu901
-
Bormann C., Lauer B., Kalmanczhelyi A., Sussmuth R., Jung G. Novel nikkomycins Lx and Lz produced by genetically engineered Streptomyces tendae Tu901. J. Antibiot. 1999, 52:582-585.
-
(1999)
J. Antibiot.
, vol.52
, pp. 582-585
-
-
Bormann, C.1
Lauer, B.2
Kalmanczhelyi, A.3
Sussmuth, R.4
Jung, G.5
-
6
-
-
0024335580
-
Isolation of Streptomyces tendae mutants with an altered nikkomycin spectrum
-
Bormann C., Mattern S., Schrempf H., Fiedler H.P., Zahner H. Isolation of Streptomyces tendae mutants with an altered nikkomycin spectrum. J. Antibiot. 1989, 42:913-918.
-
(1989)
J. Antibiot.
, vol.42
, pp. 913-918
-
-
Bormann, C.1
Mattern, S.2
Schrempf, H.3
Fiedler, H.P.4
Zahner, H.5
-
7
-
-
0030029880
-
Cloning and heterologous expression of the entire set of structural genes for nikkomycin synthesis from Streptomyces tendae Tu901 in Streptomyces lividans
-
Bormann C., Mohrle V., Bruntner C. Cloning and heterologous expression of the entire set of structural genes for nikkomycin synthesis from Streptomyces tendae Tu901 in Streptomyces lividans. J. Bacteriol. 1996, 178:1216-1218.
-
(1996)
J. Bacteriol.
, vol.178
, pp. 1216-1218
-
-
Bormann, C.1
Mohrle, V.2
Bruntner, C.3
-
8
-
-
56049096256
-
Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei
-
Brautaset T., Sletta H., Nedal A., Borgos S.E., Degnes K.F., Bakke I., Volokhan O., Sekurova O.N., Treshalin I.D., Mirchink E.P., Dikiy A., Ellingsen T.E., Zotchev S.B. Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei. Chem. Biol. 2008, 15:1198-1206.
-
(2008)
Chem. Biol.
, vol.15
, pp. 1198-1206
-
-
Brautaset, T.1
Sletta, H.2
Nedal, A.3
Borgos, S.E.4
Degnes, K.F.5
Bakke, I.6
Volokhan, O.7
Sekurova, O.N.8
Treshalin, I.D.9
Mirchink, E.P.10
Dikiy, A.11
Ellingsen, T.E.12
Zotchev, S.B.13
-
9
-
-
0018459489
-
Metabolic products of microorganisms. 181. Chitin synthase from fungi, a test model for substances with insecticidal properties
-
Brillinger G.U. Metabolic products of microorganisms. 181. Chitin synthase from fungi, a test model for substances with insecticidal properties. Arch. Microbiol. 1979, 121:71-74.
-
(1979)
Arch. Microbiol.
, vol.121
, pp. 71-74
-
-
Brillinger, G.U.1
-
10
-
-
34248357105
-
Modeling the combination of amphotericin B, micafungin, and nikkomycin Z against Aspergillus fumigatus in vitro using a novel response surface paradigm
-
Brun Y.F., Dennis C.G., Greco W.R., Bernacki R.J., Pera P.J., Bushey J.J., Youn R.C., White D.B., Segal B.H. Modeling the combination of amphotericin B, micafungin, and nikkomycin Z against Aspergillus fumigatus in vitro using a novel response surface paradigm. Antimicrob. Agents Chemother. 2007, 51:1804-1812.
-
(2007)
Antimicrob. Agents Chemother.
, vol.51
, pp. 1804-1812
-
-
Brun, Y.F.1
Dennis, C.G.2
Greco, W.R.3
Bernacki, R.J.4
Pera, P.J.5
Bushey, J.J.6
Youn, R.C.7
White, D.B.8
Segal, B.H.9
-
11
-
-
0032850662
-
Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin
-
Bruntner C., Lauer B., Schwarz W., Mohrle V., Bormann C. Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety of the peptidyl nucleoside antibiotic nikkomycin. Mol. Gen. Genet. 1999, 262:102-114.
-
(1999)
Mol. Gen. Genet.
, vol.262
, pp. 102-114
-
-
Bruntner, C.1
Lauer, B.2
Schwarz, W.3
Mohrle, V.4
Bormann, C.5
-
12
-
-
0036008124
-
Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics
-
Chen H., Hubbard B.K., O'Connor S.E., Walsh C.T. Formation of beta-hydroxy histidine in the biosynthesis of nikkomycin antibiotics. Chem. Biol. 2002, 9:103-112.
-
(2002)
Chem. Biol.
, vol.9
, pp. 103-112
-
-
Chen, H.1
Hubbard, B.K.2
O'Connor, S.E.3
Walsh, C.T.4
-
13
-
-
67449094184
-
Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H
-
Chen W., Huang T., He X., Meng Q., You D., Bai L., Li J., Wu M., Li R., Xie Z., Zhou H., Zhou X., Tan H., Deng Z. Characterization of the polyoxin biosynthetic gene cluster from Streptomyces cacaoi and engineered production of polyoxin H. J. Biol. Chem. 2009, 284:10627-10638.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10627-10638
-
-
Chen, W.1
Huang, T.2
He, X.3
Meng, Q.4
You, D.5
Bai, L.6
Li, J.7
Wu, M.8
Li, R.9
Xie, Z.10
Zhou, H.11
Zhou, X.12
Tan, H.13
Deng, Z.14
-
14
-
-
0033756147
-
Cloning, sequencing, and function of sanF: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes
-
Chen W., Zeng H., Tan H. Cloning, sequencing, and function of sanF: a gene involved in nikkomycin biosynthesis of Streptomyces ansochromogenes. Curr. Microbiol. 2000, 41:312-316.
-
(2000)
Curr. Microbiol.
, vol.41
, pp. 312-316
-
-
Chen, W.1
Zeng, H.2
Tan, H.3
-
15
-
-
0141683556
-
The blasticidin S biosynthesis gene cluster from Streptomyces griseochromogenes: sequence analysis, organization, and initial characterization
-
Cone M.C., Yin X., Grochowski L.L., Parker M.R., Zabriskie T.M. The blasticidin S biosynthesis gene cluster from Streptomyces griseochromogenes: sequence analysis, organization, and initial characterization. Chembiochem 2003, 4:821-828.
-
(2003)
Chembiochem
, vol.4
, pp. 821-828
-
-
Cone, M.C.1
Yin, X.2
Grochowski, L.L.3
Parker, M.R.4
Zabriskie, T.M.5
-
16
-
-
0025858328
-
Structure-activity relationships of the nikkomycins
-
Decker H., Zähner H., Heitsch H., König W.A., Fiedler H.P. Structure-activity relationships of the nikkomycins. J. Gen. Microbiol. 1991, 137:1805-1813.
-
(1991)
J. Gen. Microbiol.
, vol.137
, pp. 1805-1813
-
-
Decker, H.1
Zähner, H.2
Heitsch, H.3
König, W.A.4
Fiedler, H.P.5
-
17
-
-
0021344832
-
New nikkomycins by mutasynthesis and directed fermentation
-
Delzer J., Fiedler H.P., Muller H., Zahner H., Rathmann R., Ernst K., Konig W.A. New nikkomycins by mutasynthesis and directed fermentation. J. Antibiot. 1984, 37:80-82.
-
(1984)
J. Antibiot.
, vol.37
, pp. 80-82
-
-
Delzer, J.1
Fiedler, H.P.2
Muller, H.3
Zahner, H.4
Rathmann, R.5
Ernst, K.6
Konig, W.A.7
-
18
-
-
0014868818
-
Mechanism of action of the antifugal agent polyoxin D
-
Endo A., Kakiki K., Misato T. Mechanism of action of the antifugal agent polyoxin D. J. Bacteriol. 1970, 104:189-196.
-
(1970)
J. Bacteriol.
, vol.104
, pp. 189-196
-
-
Endo, A.1
Kakiki, K.2
Misato, T.3
-
19
-
-
33744537000
-
Combinatorial biosynthesis-potential and problems
-
Floss H.G. Combinatorial biosynthesis-potential and problems. J. Biotechnol. 2006, 124:242-257.
-
(2006)
J. Biotechnol.
, vol.124
, pp. 242-257
-
-
Floss, H.G.1
-
20
-
-
0017382387
-
Biosynthesis of the polyoxins, nucleoside peptide antibiotics: biosynthetic pathway for 5-O-carbamoyl-2-amino-2-deoxy-l-xylonic acid (carbamoylpolyoxamic acid)
-
Funayama S., Isono K. Biosynthesis of the polyoxins, nucleoside peptide antibiotics: biosynthetic pathway for 5-O-carbamoyl-2-amino-2-deoxy-l-xylonic acid (carbamoylpolyoxamic acid). Biochemistry 1977, 16:3121-3127.
-
(1977)
Biochemistry
, vol.16
, pp. 3121-3127
-
-
Funayama, S.1
Isono, K.2
-
21
-
-
9444248159
-
In-vitro activity of nikkomycin Z alone and in combination with polyenes, triazoles or echinocandins against Aspergillus fumigatus
-
Ganesan L.T., Manavathu E.K., Cutright J.L., Alangaden G.J., Chandrasekar P.H. In-vitro activity of nikkomycin Z alone and in combination with polyenes, triazoles or echinocandins against Aspergillus fumigatus. Clin. Microbiol. Infect. 2004, 10:961-966.
-
(2004)
Clin. Microbiol. Infect.
, vol.10
, pp. 961-966
-
-
Ganesan, L.T.1
Manavathu, E.K.2
Cutright, J.L.3
Alangaden, G.J.4
Chandrasekar, P.H.5
-
22
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
Gust B., Challis G.L., Fowler K., Kieser T., Chater K.F. PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin. Proc. Natl. Acad. Sci. USA 2003, 100:1541-1546.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1541-1546
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
-
23
-
-
47249115312
-
Combinatorial biosynthesis, metabolic engineering and mutasynthesis for the generation of new aminocoumarin antibiotics
-
Heide L., Gust B., Anderle C., Li S.M. Combinatorial biosynthesis, metabolic engineering and mutasynthesis for the generation of new aminocoumarin antibiotics. Curr. Top. Med. Chem. 2008, 8:667-679.
-
(2008)
Curr. Top. Med. Chem.
, vol.8
, pp. 667-679
-
-
Heide, L.1
Gust, B.2
Anderle, C.3
Li, S.M.4
-
24
-
-
0016159750
-
Studies on the mode of action of polyoxins. VI. Effect of polyoxin B on chitin synthesis in polyoxin-sensitive and resistant strains of Alternaria kikuchiana
-
Hori M., Eguchi J., Kakiki K., Misato T. Studies on the mode of action of polyoxins. VI. Effect of polyoxin B on chitin synthesis in polyoxin-sensitive and resistant strains of Alternaria kikuchiana. J. Antibiot. 1974, 27:260-266.
-
(1974)
J. Antibiot.
, vol.27
, pp. 260-266
-
-
Hori, M.1
Eguchi, J.2
Kakiki, K.3
Misato, T.4
-
25
-
-
0014682610
-
Studies on polyoxins, antifungal antibiotics. 13. The structure of polyoxins
-
Isono K., Asahi K., Suzuki S. Studies on polyoxins, antifungal antibiotics. 13. The structure of polyoxins. J. Am. Chem. Soc. 1969, 91:7490-7505.
-
(1969)
J. Am. Chem. Soc.
, vol.91
, pp. 7490-7505
-
-
Isono, K.1
Asahi, K.2
Suzuki, S.3
-
26
-
-
0014250821
-
The structures of polyoxins A and B
-
Isono K., Suzuki S. The structures of polyoxins A and B. Tetrahedron Lett. 1968, 9:1133-1137.
-
(1968)
Tetrahedron Lett.
, vol.9
, pp. 1133-1137
-
-
Isono, K.1
Suzuki, S.2
-
27
-
-
0030633665
-
Use of azoles for systemic antifungal therapy
-
Kauffman C.A., Carver P.L. Use of azoles for systemic antifungal therapy. Adv. Pharmacol. 1997, 39:143-189.
-
(1997)
Adv. Pharmacol.
, vol.39
, pp. 143-189
-
-
Kauffman, C.A.1
Carver, P.L.2
-
28
-
-
0003869903
-
-
John Innes Foundation, Norwich, UK
-
Kieser T., Bibb M.J., Buttner M.J., Chater K.F., Hopwood D.A. Practical Streptomyces Genetics 2000, John Innes Foundation, Norwich, UK.
-
(2000)
Practical Streptomyces Genetics
-
-
Kieser, T.1
Bibb, M.J.2
Buttner, M.J.3
Chater, K.F.4
Hopwood, D.A.5
-
29
-
-
0037087290
-
Inhibitory effect of nikkomycin Z on chitin synthases in Candida albicans
-
Kim M.K., Park H.S., Kim C.H., Park H.M., Choi W. Inhibitory effect of nikkomycin Z on chitin synthases in Candida albicans. Yeast 2002, 19:341-349.
-
(2002)
Yeast
, vol.19
, pp. 341-349
-
-
Kim, M.K.1
Park, H.S.2
Kim, C.H.3
Park, H.M.4
Choi, W.5
-
30
-
-
0026089876
-
Synthesis and biological evaluation of dipeptidyl and tripeptidyl polyoxin and nikkomycin analogues as anticandidal prodrugs
-
Krainer E., Becker J.M., Naider F. Synthesis and biological evaluation of dipeptidyl and tripeptidyl polyoxin and nikkomycin analogues as anticandidal prodrugs. J. Med. Chem. 1991, 34:174-180.
-
(1991)
J. Med. Chem.
, vol.34
, pp. 174-180
-
-
Krainer, E.1
Becker, J.M.2
Naider, F.3
-
31
-
-
0000853940
-
Molecular characterization of two genes from Streptomyces tendae Tu901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin
-
Lauer B., Russwurm R., Bormann C. Molecular characterization of two genes from Streptomyces tendae Tu901 required for the formation of the 4-formyl-4-imidazolin-2-one-containing nucleoside moiety of the peptidyl nucleoside antibiotic nikkomycin. Eur. J. Biochem. 2000, 267:1698-1706.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 1698-1706
-
-
Lauer, B.1
Russwurm, R.2
Bormann, C.3
-
32
-
-
0035145615
-
Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin
-
Lauer B., Russwurm R., Schwarz W., Kalmanczhelyi A., Bruntner C., Rosemeier A., Bormann C. Molecular characterization of co-transcribed genes from Streptomyces tendae Tu901 involved in the biosynthesis of the peptidyl moiety and assembly of the peptidyl nucleoside antibiotic nikkomycin. Mol. Gen. Genet. 2001, 264:662-673.
-
(2001)
Mol. Gen. Genet.
, vol.264
, pp. 662-673
-
-
Lauer, B.1
Russwurm, R.2
Schwarz, W.3
Kalmanczhelyi, A.4
Bruntner, C.5
Rosemeier, A.6
Bormann, C.7
-
33
-
-
49249106618
-
The mildiomycin biosynthesis: initial steps for sequential generation of 5-hydroxymethylcytidine 5'-monophosphate and 5-hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119
-
Li L., Xu Z., Xu X., Wu J., Zhang Y., He X., Zabriskie T.M., Deng Z. The mildiomycin biosynthesis: initial steps for sequential generation of 5-hydroxymethylcytidine 5'-monophosphate and 5-hydroxymethylcytosine in Streptoverticillium rimofaciens ZJU5119. Chembiochem 2008, 9:1286-1294.
-
(2008)
Chembiochem
, vol.9
, pp. 1286-1294
-
-
Li, L.1
Xu, Z.2
Xu, X.3
Wu, J.4
Zhang, Y.5
He, X.6
Zabriskie, T.M.7
Deng, Z.8
-
34
-
-
67650759674
-
PolR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis
-
Li R., Xie Z., Tian Y., Yang H., Chen W., You D., Liu G., Deng Z., Tan H. polR, a pathway-specific transcriptional regulatory gene, positively controls polyoxin biosynthesis in Streptomyces cacaoi subsp. asoensis. Microbiology 2009, 55:1819-1831.
-
(2009)
Microbiology
, vol.55
, pp. 1819-1831
-
-
Li, R.1
Xie, Z.2
Tian, Y.3
Yang, H.4
Chen, W.5
You, D.6
Liu, G.7
Deng, Z.8
Tan, H.9
-
35
-
-
74349130880
-
PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi
-
Li R., Liu G., Xie Z., He X., Chen W., Deng Z., Tan H. PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi. Mol. Microbiol. 2010, 75:349-364.
-
(2010)
Mol. Microbiol.
, vol.75
, pp. 349-364
-
-
Li, R.1
Liu, G.2
Xie, Z.3
He, X.4
Chen, W.5
Deng, Z.6
Tan, H.7
-
36
-
-
71549150297
-
Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes
-
Liao G., Li J., Li L., Yang H., Tian Y., Tan H. Selectively improving nikkomycin Z production by blocking the imidazolone biosynthetic pathway of nikkomycin X and uracil feeding in Streptomyces ansochromogenes. Microb. Cell Fact. 2009, 8:61.
-
(2009)
Microb. Cell Fact.
, vol.8
, pp. 61
-
-
Liao, G.1
Li, J.2
Li, L.3
Yang, H.4
Tian, Y.5
Tan, H.6
-
37
-
-
46749129445
-
SanN encoding a dehydrogenase is essential for nikkomycin biosynthesis in Streptomyces ansochromogenes
-
Ling H., Wang G., Li J., Tan H. sanN encoding a dehydrogenase is essential for nikkomycin biosynthesis in Streptomyces ansochromogenes. J. Microbiol. Biotechnol. 2008, 18:397-403.
-
(2008)
J. Microbiol. Biotechnol.
, vol.18
, pp. 397-403
-
-
Ling, H.1
Wang, G.2
Li, J.3
Tan, H.4
-
38
-
-
15944401749
-
A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development
-
Liu G., Tian Y., Yang H., Tan H. A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in Streptomyces ansochromogenes that also influences colony development. Mol. Microbiol. 2005, 55:1855-1866.
-
(2005)
Mol. Microbiol.
, vol.55
, pp. 1855-1866
-
-
Liu, G.1
Tian, Y.2
Yang, H.3
Tan, H.4
-
39
-
-
33646092531
-
Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics
-
Miao V., Coeffet-Le Gal M.F., Nguyen K., Brian P., Penn J., Whiting A., Steele J., Kau D., Martin S., Ford R., Gibson T., Bouchard M., Wrigley S.K., Baltz R.H. Genetic engineering in Streptomyces roseosporus to produce hybrid lipopeptide antibiotics. Chem. Biol. 2006, 13:269-276.
-
(2006)
Chem. Biol.
, vol.13
, pp. 269-276
-
-
Miao, V.1
Coeffet-Le Gal, M.F.2
Nguyen, K.3
Brian, P.4
Penn, J.5
Whiting, A.6
Steele, J.7
Kau, D.8
Martin, S.9
Ford, R.10
Gibson, T.11
Bouchard, M.12
Wrigley, S.K.13
Baltz, R.H.14
-
40
-
-
33646118511
-
SanJ, an ATP-dependent picolinate-CoA ligase, catalyzed the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes
-
Niu G., Liu G., Tian Y., Tan H. SanJ, an ATP-dependent picolinate-CoA ligase, catalyzed the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in Streptomyces ansochromogenes. Metab. Eng. 2006, 8:183-195.
-
(2006)
Metab. Eng.
, vol.8
, pp. 183-195
-
-
Niu, G.1
Liu, G.2
Tian, Y.3
Tan, H.4
-
41
-
-
67049107844
-
Pharmacokinetics of nikkomycin Z after single rising oral doses
-
Nix D.E., Swezey R.R., Hector R., Galgiani J.N. Pharmacokinetics of nikkomycin Z after single rising oral doses. Antimicrob. Agents Chemother. 2009, 53:2517-2521.
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 2517-2521
-
-
Nix, D.E.1
Swezey, R.R.2
Hector, R.3
Galgiani, J.N.4
-
42
-
-
50249084003
-
Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering
-
Olano C., Lombo F., Mendez C., Salas J.A. Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering. Metab. Eng. 2008, 10:281-292.
-
(2008)
Metab. Eng.
, vol.10
, pp. 281-292
-
-
Olano, C.1
Lombo, F.2
Mendez, C.3
Salas, J.A.4
-
43
-
-
67649622396
-
Application of the Ugi reaction for the one-pot synthesis of uracil polyoxin C analogues
-
Plant A., Thompson P., Williams D.M. Application of the Ugi reaction for the one-pot synthesis of uracil polyoxin C analogues. J. Org. Chem. 2009, 74:4870-4873.
-
(2009)
J. Org. Chem.
, vol.74
, pp. 4870-4873
-
-
Plant, A.1
Thompson, P.2
Williams, D.M.3
-
44
-
-
67649872012
-
Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles
-
Sanchez C., Salas A.P., Brana A.F., Palomino M., Pineda-Lucena A., Carbajo R.J., Mendez C., Moris F., Salas J.A. Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles. Chem. Commun. (Camb.) 2009, 4118-4120.
-
(2009)
Chem. Commun. (Camb.)
, pp. 4118-4120
-
-
Sanchez, C.1
Salas, A.P.2
Brana, A.F.3
Palomino, M.4
Pineda-Lucena, A.5
Carbajo, R.J.6
Mendez, C.7
Moris, F.8
Salas, J.A.9
-
45
-
-
0035313411
-
Combinatorial biosynthesis of polyketides and nonribosomal peptides
-
Staunton J., Wilkinson B. Combinatorial biosynthesis of polyketides and nonribosomal peptides. Curr. Opin. Chem. Biol. 2001, 5:159-164.
-
(2001)
Curr. Opin. Chem. Biol.
, vol.5
, pp. 159-164
-
-
Staunton, J.1
Wilkinson, B.2
-
46
-
-
84873781052
-
A new antibiotic, polyoxin A
-
Suzuki S., Isono K., Nagatsu J., Mizutani T., Kawashima Y., Mizuno T. A new antibiotic, polyoxin A. J. Antibiot. 1965, 18:131.
-
(1965)
J. Antibiot.
, vol.18
, pp. 131
-
-
Suzuki, S.1
Isono, K.2
Nagatsu, J.3
Mizutani, T.4
Kawashima, Y.5
Mizuno, T.6
-
47
-
-
33646866770
-
Polyoxin N, a new member of the polyoxin family
-
Uramoto M., Matsuoka M., Liehr J.G., McCloskey J.A., Isono K. Polyoxin N, a new member of the polyoxin family. Agric. Biol. Chem. 1981, 45:1901-1902.
-
(1981)
Agric. Biol. Chem.
, vol.45
, pp. 1901-1902
-
-
Uramoto, M.1
Matsuoka, M.2
Liehr, J.G.3
McCloskey, J.A.4
Isono, K.5
-
49
-
-
42949164985
-
Combinatorial biosynthesis of natural products
-
Zhang W., Tang Y. Combinatorial biosynthesis of natural products. J. Med. Chem. 2008, 51:2629-2633.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 2629-2633
-
-
Zhang, W.1
Tang, Y.2
|