Translocation of an antibody transgene requires AID and occurs by interchromosomal switching to all switch regions except the mu switch region

European Journal of Immunology

Volumn 41, Issue 5, 2011, Pages 1456-1464

  Shansab, Maryam ^a   Eccleston, Jennifer M ^a   Selsing, Erik ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

B cells; Immune regulation; Immunoglobulins; Molecular immunology

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; GENE LOCUS; GENE SWITCHING; GENE TRANSLOCATION; IMMUNOGLOBULIN HEAVY CHAIN GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SEQUENCE ANALYSIS; TRANSGENE;

ANIMALS; BLOTTING, SOUTHERN; CYTIDINE DEAMINASE; GENES, IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN SWITCH REGION; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, TRANSGENIC; POLYMERASE CHAIN REACTION; RECOMBINATION, GENETIC; TRANSGENES; TRANSLOCATION, GENETIC;

EID: 79955143524     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201041077     Document Type: Article

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