Transfer of PAMAM dendrimers across human placenta: Prospects of its use as drug carrier during pregnancy

Journal of Controlled Release

Volumn 150, Issue 3, 2011, Pages 326-338

  Menjoge, Anupa R ^a,b   Rinderknecht, Amber L ^c   Navath, Raghavendra S ^a,b   Faridnia, Masoud ^c   Kim, Chong J ^b   Romero, Roberto ^b   Miller, Richard K ^c   Kannan, Rangaramanujam M ^a,b  

^a WAYNE STATE UNIVERSITY   (United States)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Biodistribution; Drug delivery; Endocytosis; Human placenta; Paracellular; Pharmacokinetic; Transport

Indexed keywords

BIODISTRIBUTIONS; ENDOCYTOSIS; HUMAN PLACENTA; PARACELLULAR; TRANSPORT;

BIOCHEMISTRY; CONJUGATED POLYMERS; CYTOLOGY; DENDRIMERS; DRUG DELIVERY; FLUORESCENCE; MICROCIRCULATION; MOLECULAR BIOLOGY; PHARMACOKINETICS;

FUNCTIONAL POLYMERS;

DENDRIMER; DRUG CARRIER; IMMUNOGLOBULIN G; PHENAZONE; POLYAMIDOAMINE;

ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOPLASM; DRUG DELIVERY SYSTEM; FETOMATERNAL TRANSFUSION; FETUS CIRCULATION; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; PLACENTAL TRANSFER; PREGNANCY; PRIORITY JOURNAL; SYNCYTIOTROPHOBLAST; ULTRAVIOLET RADIATION;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIPYRINE; BIOLOGICAL TRANSPORT; DENDRIMERS; DRUG CARRIERS; FEMALE; HUMANS; PLACENTA; PREGNANCY;

EID: 79955061239     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.11.023     Document Type: Article

References (49)

1. A.R. Menjoge, R.M. Kannan, and D.A. Tomalia Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications Drug Discov. Today 15 2010 171 185
2. A.T. Florence, T. Sakthivel, and I. Toth Oral uptake and translocation of a polylysine dendrimer with a lipid surface J. Control. Release 65 2000 253 259 (Pubitemid 30122930)
3. A. Casas, S. Battah, G. Di Venosa, P. Dobbin, L. Rodriguez, H. Fukuda, A. Batlle, and A.J. MacRobert Sustained and efficient porphyrin generation in vivo using dendrimer conjugates of 5-ALA for photodynamic therapy J. Control. Release 135 2009 136 143
4. Th.F. Vandamme, and L. Brobeck Poly(amidoamine) dendrimers as ophthalmic vehicles for ocular delivery of pilocarpine nitrate and tropicamide J. Control. Release 102 2005 23 38 (Pubitemid 40093773)
5. G. Cevc, and U. Vierl Nanotechnology and the transdermal route: A state of the art review and critical appraisal J. Control. Release 141 2010 277 299
6. R. Wiwattanapatapee, L. Lomlim, and K. Saramunee Dendrimer conjugates for colonic delivery of 5-aminosalicylic acid J. Control. Release 88 2003 1 9 (Pubitemid 36173949)
7. R.S. Navath, Y.E. Kurtoglu, B. Wang, S. Kannan, R. Romero, and R.M. Kannan Dendrimer-drug conjugates for tailored intracellular drug release based on glutathione levels Bioconjug. Chem. 19 2008 2446 2455
8. Y.E. Kurtoglu, R.S. Navath, B. Wang, S. Kannan, R. Romero, and R.M. Kannan Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery Biomaterials 30 2009 2112 2121
9. S.S. Nigavekar, L.Y. Sung, M. Llanes, A. El-Jawahri, T.S. Lawrence, C.W. Becker, L. Balogh, and M.K. Khan 3H dendrimer nanoparticle organ/tumor distribution Pharm. Res. 21 2004 476 483
10. A.R. Menjoge, R.S. Navath, A. Asad, S. Kannan, C.J. Kim, R. Romero, and R.M. Kannan Transport and biodistribution of dendrimers across human fetal membranes: implications for intravaginal administration of dendrimer-drug conjugates Biomaterials 31 2010 5007 5021
11. K.L. Audus Controlling drug delivery across the placenta Eur. J. Pharm. Sci. 8 1999 161 165 (Pubitemid 29324643)
12. A. Lemancewicz, H. Laudanska, T. Laudanski, A. Karpiuk, and S. Batra Permeability of fetal membranes to calcium and magnesium: possible role in preterm labour Hum. Reprod. 15 2000 2018 2022
13. A.E. Seeds Osmosis across term human placental membranes Am. J. Physiol. 219 1970 551 554
14. C. Ampasavate, G.A. Chandorkar, D.G. Vande Velde, J.F. Stobaugh, and K.L. Audus Transport and metabolism of opioid peptides across BeWo cells, an in vitro model of the placental barrier Int. J. Pharm. 233 2002 85 98 (Pubitemid 34230421)
15. H. Schneider, and R.K. Miller Receptor-mediated uptake and transport of macromolecules in the human placenta Int. J. Dev. Biol. 54 2010 367 375
16. B.M. Polliotti, M. Panigel, and R.K. Miller Free vitamin B12 and transcobalamin II-vitamin B12 complex uptake by the visceral yolk sac of the Sprague-Dawley rat: effect of inhibitors Reprod. Toxicol. 11 1997 617 626
17. R.E. Perez-D'Gregorio, and R.K. Miller Transport and endogenous release of vitamin B12 in the dually perfused human placenta J. Pediatr. 132 1998 35 42
18. R. Fuchs, and I. Ellinger Endocytic and transcytotic processes in villous syncytiotrophoblast: role in nutrient transport to the human fetus Traffic 5 2004 725 738 (Pubitemid 39307257)
19. J.H. Boal, M.A. Plessinger, C. van den Reydt, and R.K. Miller Pharmacokinetic and toxicity studies of AZT (zidovudine) following perfusion of human term placenta for 14 hours Toxicol. Appl. Pharmacol. 143 1997 13 21 (Pubitemid 27130602)
20. B.V. Sastry Techniques to study human placental transport Adv. Drug Deliv. Rev. 38 1999 17 39 (Pubitemid 29216951)
21. R.K. Miller, P.J. Wier, D. Maulik, and P.A. di Sant'Agnese Human placenta in vitro: characterization during 12 h of dual perfusion Contrib. Gynecol. Obstet. 13 1985 77 84 (Pubitemid 15120216)
22. H. Schneider, M. Panigel, and J. Dancis Transfer across the perfused human placenta of antipyrine, sodium and leucine Am. J. Obstet. Gynecol. 114 1972 822 828
23. R.K. Miller, K. Mace, B. Polliotti, R. DeRita, W. Hall, and G. Treacy Marginal transfer of ReoPro (Abciximab) compared with immunoglobulin G (F105), inulin and water in the perfused human placenta in vitro Placenta 24 2003 727 738 (Pubitemid 37184795)
24. P. Myllynen, P. Pienimaki, and K. Vahakangas Human placental perfusion method in the assessment of transplacental passage of antiepileptic drugs Toxicol. Appl. Pharmacol. 207 2005 489 494
25. M. Saunders Transplacental transport of nanomaterials Adv. Rev. 1 2009 671 684
26. R. Bajoria, and S. Soorana Liposome as a drug carrier system: Prospects for safer prescribing during pregnancy Placenta 19 1998 265 287
27. P.K. Myllynen, M.J. Loughran, C.V. Howard, R. Sormunen, A.A. Walsh, and K.H. Vahakangas Kinetics of gold nanoparticles in the human placenta Reprod. Toxicol. 26 2008 130 137
28. A. Rinderknecht, G. Oberdörster, K.M. Bentley, R. Gelein, A. Elder, K. Brewer, and R.K. Miller Nanoparticles and the maternal-fetal barrier: do they cross? Birth Defects Res. A 85 2009 401
29. P. Wick, A. Malek, P. Manser, D. Meili, X. Maeder-Althaus, L. Diener, P.A. Diener, A. Zisch, H.F. Krug, and U. von Mandach Barrier capacity of human placenta for nanosized materials Environ. Health Perspect. 118 2010 432 436
30. A. Malek, R. Sager, K.U. Eckardt, C. Bauer, and H. Schneider Lack of transport of erythropoietin across the human placenta as studied by an in vitro perfusion system Pflugers Arch. 427 1994 157 161 (Pubitemid 24131567)
31. R. Bajoria, T.A. Ryder, and N.M. Fisk Transport and metabolism of thyrotrophin-releasing hormone across the fetal membrane J. Clin. Endocrinol. Metab. 82 1997 3399 3407 (Pubitemid 27419095)
32. R. Bajoria, and N.M. Fisk Permeability of human placenta and fetal membranes to thyrotropin-stimulating hormone in vitro Pediatr. Res. 43 1998 621 628 (Pubitemid 28196454)
33. D. Edwards, C.J. Jones, C.P. Sibley, and D.M. Nelson Paracellular permeability pathways in the human placenta: a quantitative and morphological study of maternal-fetal transfer of horseradish peroxidase Placenta 14 1993 63 73 (Pubitemid 23082139)
34. L. Nicolle Use of antimicrobials during pregnancy Can. Fam. Physician 33 1987 1247 1251
35. R.K. Miller, P. Wier, R. Perez-D'Gregorio, C. Eisenmann, P.A. di Sant'Agnese, Y. Shah, and L.N. Jessee Human dual placental perfusions criteria for toxicity evaluations Meth. Toxicol. 3B 1993 246 259
36. R. Bajoria, and S. Sooranna Liposome as a drug carrier system: Prospects for safer prescribing during pregnancy Placenta 19 1998 265 287
37. F. Liu, M.J. Soares, and K.L. Audus Permeability properties of monolayers of the human trophoblast cell line BeWo Am. J. Physiol. 273 1997 C1596 1604
38. P.J. Wier, R.K. Miller, D. Maulik, and P.A. DiSant'Agnese Toxicity of cadmium in the perfused human placenta Toxicol. Appl. Pharmacol. 105 1990 156 171 (Pubitemid 20287032)
39. P.L. Tuma, and A.L. Hubbard Transcytosis: crossing cellular barriers Physiol. Rev. 83 2003 871 932 (Pubitemid 36833216)
40. J. Giri, M.S. Diallo, W.A. Goddard, N.F. Dalleska, X. Fang, and Y. Tang Partitioning of poly(amidoamine) dendrimers between n-octanol and water Environ. Sci. Technol. 43 2009 5123 5129
41. T.W. Lyden, J.M. Robinson, S. Tridandapani, J.L. Teillaud, S.A. Garber, J.M. Osborne, J. Frey, P. Budde, and C.L. Anderson The Fc receptor for IgG expressed in the villus endothelium of human placenta is Fc gamma RIIb2 J. Immunol. 166 2001 3882 3889 (Pubitemid 32224914)
42. S. Kertschanska, G. Kosanke, and P. Kaufmann Pressure dependence of so-called transtrophoblastic channels during fetal perfusion of human placental villi Microsc. Res. Tech. 38 1997 52 62 (Pubitemid 27328947)
43. L. Leach, and J.A. Firth Structure and permeability of human placental microvasculature Microsc. Res. Tech. 38 1997 137 144 (Pubitemid 27328954)
44. K. Benirschke, P. Kaufmann, and R.N. Baergen Pathology of the Human Placenta fifth edition 2006 Springer Science+Business Media Inc. New York
45. B.F. King Absorption of peroxidase-conjugated immunoglobulin G by human placenta: an in vitro study Placenta 3 1982 395 406 (Pubitemid 12004790)
46. H. Schneider Placental transport function Reprod. Fertil. Dev. 3 1991 345 353
47. E. Jauniaux, C. Lees, D. Jurkovic, S. Campbell, and B. Gulbis Transfer of inulin across the first-trimester human placenta Am. J. Obstet. Gynecol. 176 1997 33 36 (Pubitemid 127780743)
48. S. Sudhakaran, H. Ghabrial, R.L. Nation, D.C. Kong, N.M. Gude, P.W. Angus, and C.R. Rayner Differential bidirectional transfer of indinavir in the isolated perfused human placenta Antimicrob. Agents Chemother. 49 2005 1023 1028 (Pubitemid 40327719)
49. M. Kovo, N. Kogman, O. Ovadia, I. Nakash, A. Golan, and A. Hoffman Carrier-mediated transport of metformin across the human placenta determined by using the ex vivo perfusion of the placental cotyledon model Prenat. Diagn. 28 2008 544 548 (Pubitemid 351946958)