The protective effect of peony extract on acute myocardial infarction in rats

Phytomedicine

Volumn 18, Issue 6, 2011, Pages 451-457

  Mo, Xiaoyan ^a   Zhao, Nana ^a   Du, Xiaoyang ^a   Bai, Liyuan ^a   Liu, Jiankang ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Anticoagulation; Antioxidants; Apoptosis; Cytokines; Myocardial infarction; Paeonia rubra; Total peony glucosides

Indexed keywords

2 HYDROXYBUTYRATE DEHYDROGENASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CREATINE KINASE; CREATINE KINASE MB; FAS ANTIGEN; INTERLEUKIN 10; ISOSORBIDE DINITRATE; LACTATE DEHYDROGENASE; PAEONIA EXTRACT; PROTEIN BAX; PROTEIN BCL 2; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA;

ACUTE HEART INFARCTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BLOOD CLOTTING TIME; CELL ISOLATION; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG MEGADOSE; ENZYME ACTIVITY; FEMALE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LOW DRUG DOSE; MALE; NONHUMAN; OXIDATIVE STRESS; PARTIAL THROMBOPLASTIN TIME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHAM PROCEDURE; THROMBIN TIME;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BIOLOGICAL MARKERS; BLOOD COAGULATION; BLOOD PRESSURE; CORONARY VESSELS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENZYMES; FEMALE; HEART; LIGATION; LIPID PEROXIDATION; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; OXIDATIVE STRESS; PAEONIA; PARTIAL THROMBOPLASTIN TIME; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; RANDOM ALLOCATION; RATS; THROMBIN TIME; VENTRICULAR PRESSURE;

ANIMALIA; PAEONIA; RATTUS;

EID: 79955044466     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.10.003     Document Type: Article

References (16)

1. M. Elg, D. Gustafsson, and S. Carlsson Antithrombotic effects and bleeding time of thrombin inhibitors and warfarin in the rat Thromb. Res. 94 3 1999 187 197 (Pubitemid 29217200)
2. H Esterbauer Cytotoxicity and genootoxicity of lipid oxidation products Am. J. Clin. Nutr. 57 Suppl. 1993 785S 786S
3. B. Jiang, J. Qiao, Y. Yang, and Y Lu Inhibitory effect of paeoniflorin on the inflammatory vicious cycle between adipocytes and macrophages J. Cell Biochem. April 24 2009 (Epub ahead of print)
4. J. Kajstura, W. Cheng, K. Reiss, W.A. Clark, E.H. Sonnenblick, S. Krajewski, J.C. Reed, G. Olivetti, and P. Anversa Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats Lab. Invest. 74 1 1996 86 107 (Pubitemid 26041012)
5. D.Z. Liu, K.Q. Xie, X.Q. Ji, Y. Ye, C.L. Jiang, and X.Z. Zhu Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists Br. J. Pharmacol. 146 4 2005 604 611 (Pubitemid 41487077)
6. J. Long, C. Liu, L. Sun, H. Gao, and J. Liu Neuronal mitochondrial toxicity of malondialdehyde: inhibitory effects on respiratory function and enzyme activities in rat brain mitochondria Neurochem. Res. 34 4 2009 786 794
7. G. Olivetti, F. Quaini, R. Sala, C. Lagrasta, D. Corradi, E. Bonacina, S.R. Gambert, E. Cigola, and P. Anversa Acute myocardial infarction in humans is associated with activation of programmed myocyte cell death in the surviving portion of the heart J. Mol. Cell. Cardiol. 28 9 1996 2005 2016 (Pubitemid 26340560)
8. T. Piao, M. Xy, and L. Rz Study on the free radical-scavenging and anticoagulant activities of total paeony glycoside in vitro Zhongguo Yao Fang 9 2007 643 646
9. X. Shen, X. Mo, and X. Du Total peony glucosides protect iso-prenaline-induced myocardial ischemia in rats Zhongguo Yaolixue Tongbao Chinese Pharmacology Bulletin 23 10 2007 1300 1305
10. J. Su, P. Zhang, J.J. Zhang, X.M. Qi, Y.G. Wu, and J.J. Shen Effects of total glucosides of paeony on oxidative stress in the kidney from diabetic rats Phytomedicine 17 3-4 2010 254 260
11. Wang, A., Shen, F., Liang, Y., Wang, J., 2010. Marrow-derived MSCs and atorvastatin improve cardiac function in rat model of AMI. Int. J. Cardiol. 2010 Mar 9. [E-pub ahead of print].
12. H. Wu, Z. Zhu, G. Zhang, L. Zhao, H. Zhang, D. Zhu, and Y. Chai Comparative pharmacokinetic study of paeoniflorin after oral administration of pure paeoniflorin, extract of Cortex Moutan and Shuang-Dan prescription to rats J. Ethnopharmacol. 125 3 2009 444 449
13. J. Yang, G. Zhang, J. Tian, C. Li, W. Jiang, Y. Xing, H. Zhu, J. Hou, H. Xu, and J. Wu Cardioprotective effect of SMND-309, a novel derivate of salvianolic acid B on acute myocardial infarction in rats Basic Clin. Pharmacol. Toxicol. 106 4 2010 317 323
14. P. Zhang, J.J. Zhang, J. Su, X.M. Qi, Y.G. Wu, and J.J. Shen Effect of total glucosides of paeony on the expression of nephrin in the kidneys from diabetic rats Am. J. Chin. Med. 37 2 2009 295 307
15. Y.Q. Zheng, and W. Wei Total glucosides of paeony suppresses adjuvant arthritis in rats and intervenes cytokine-signaling between different types of synoviocytes Int. Immunopharmacol. 5 10 2005 1560 1573 (Pubitemid 40967914)
16. L.Y. Zheng, J.Q. Pan, and J.H. Lv Effects of total glucosides of paeony on enhancing insulin sensitivity and antagonizing nonalcoholic fatty liver in rats Zhongguo Zhong Yao Za Zhi 33 20 2008 2385 2390