Versatile co-expression of graft-protective proteins using 2A-linked cassettes

Xenotransplantation

Volumn 18, Issue 2, 2011, Pages 121-130

  Fisicaro, Nella ^a   Londrigan, Sarah L ^b,f   Brady, Jamie L ^b   Salvaris, Evelyn ^a   Nottle, Mark B ^c   O'Connell, Philip J ^d   Robson, Simon C ^e   D'Apice, Anthony J F ^a,f   Lew, Andrew M ^b   Cowan, Peter J ^a,f  

^a ST VINCENT S HOSPITAL   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c UNIVERSITY OF ADELAIDE   (Australia)

^d WESTMEAD HOSPITAL   (Australia)

^e HARVARD MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

2A; genetic modification; transgene co expression; xenotransplantation

Indexed keywords

CD39 ANTIGEN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DECAY ACCELERATING FACTOR; FURIN; GALACTOSYLTRANSFERASE; HYGROMYCIN; THROMBOMODULIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN COS7; CELL SURFACE; CONTROLLED STUDY; FIBROBLAST; FLOW CYTOMETRY; GENE CASSETTE; GENETIC TRANSFECTION; INSULINOMA; MOUSE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN TRANSPORT; SWINE; TRANSGENICS; TRANSIENT TRANSFECTION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIGENS, CD; ANTIGENS, CD55; APYRASE; BASE SEQUENCE; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; DNA TRANSPOSABLE ELEMENTS; FIBROBLASTS; GALACTOSYLTRANSFERASES; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; GRAFT SURVIVAL; HUMANS; IMMUNOCONJUGATES; INSULINOMA; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PANCREATIC NEOPLASMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SWINE; THROMBOMODULIN; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 79955038546     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/j.1399-3089.2011.00631.x     Document Type: Article

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