Memory enhancing and antioxidant properties of fermented Chongmyung-tang

Natural Product Sciences

Volumn 16, Issue 2, 2010, Pages 93-98

  Nam II, Jung ^a   Park, Yeun Woo ^a   Jeon, Hoon ^b,c  

^a Hupharm Inc   (South Korea)

^b Woosuk University   (South Korea)

^c Center for Healthcare Technology Development   (South Korea)

Author keywords

Antioxidant; Chongmyung tang; Fermentation; Memory enhancing

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; CHONGMYUNG TANG; HERBACEOUS AGENT; NOOTROPIC AGENT; SCOPOLAMINE; UNCLASSIFIED DRUG;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ASPERGILLUS ORYZAE; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DRUG ACTIVITY; EXTRACTIVE FERMENTATION; INHIBITION KINETICS; MALE; MEMORY DISORDER; MEMORY ENHANCING ACTIVITY; MOUSE; NONHUMAN; SACCHAROMYCES CEREVISIAE;

EID: 79955031200     PISSN: 12263907     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. An, K.Y., Lee, S.K., Lee, S.H., Lee, J.W., Shin, J.B., Song, B.K., and Lee, E.J., Neuroprotective effect of Gagamchongmyung-tang on the deficits of learning and memory by MCAO in the Rat. J. Korean Oriental Med. 28, 1-12 (2007).
2. Bartus, R.T., Dean, R.L., Beer, B., and Lippa, A.S., The cholinergic hypothesis of geriatric memory dysfunction. Science 217, 408-414 (1982).
3. Chen, L.N., Ng, C.C., Wang, C.Y., and Chang, T.L., Lactic fermentation and antioxidant activity of Zingiberaceae plants in Taiwan. Int. J. Food Sci. Nutr. 60, 57-66 (2009).
4. Dreher, D. and Junod, A.F., Role of oxygen free radicals in cancer development. Eur. J. Cancer 32, 30-38 (1996).
5. El-Sherbiny, D.A., Khalifa, A.E., Attia, A.S., and Eldenshary, E.E.S., Hypericum perforatum extract demonstrates antioxidant properties against elevated rat brain oxidative status induced by amnestic dose of scopolamine. Pharmacol. Biochem. Behav. 76, 523-533 (2003).
6. Fernandez-Orozco, R, Frias, J, Muñoz, R., Zielinski, H., Piskula, M.K., Kozlowska, H., and Vidal-Valverde, C., Fermentation as a bio-process to obtain functional soybean flours. J. Agric. Food. Chem. 55, 8972-8979 (2007).
7. Floyd, R.A. and Hensley, K., Oxidative stress in brain aging-implications for therapeutics of neurodegenerative diseases. Neurobiol. Aging 23, 795-807 (2002).
8. Fodale, V., Quattrone, D., Trecroci, C., Caminiti, V., and Santamaria, L.B., Alzheimer's disease and anaesthesia: implications for the central cholinergic system. Br. J. Anaesth. 97, 445-452 (2006).
9. Georgetti, S.R., Vicentini, F.T., Yokoyama, C.Y., Borin, M.F., Spadaro, A.C., and Fonseca, M.J., Enhanced in vitro and in vivo antioxidant activity and mobilization of free phenolic compounds of soybean flour fermented with different beta-glucosidase-producing fungi. J. Appl. Microbiol. 106, 459-466 (2009).
10. Gilgun-Sherki, Y., Melamed, E., and Offen, D., Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier. Neuropharmacol. 40, 959-975 (2001).
11. Goo, B.S. and Lee, D.W., Antioxdative Effect of the Essential Oil form the Rhizomes of Acorus gramineus. J. Life Sci. 11, 503-508 (2001).
12. Gug, Y.J., Choi, H., Kim, T.H., Kang, H.W., and Lyu, Y.S., Chongmyungtang Inhibits the Cytotoxicity of Beta-amyloid in Neuro 2A Neuroblastoma Cells. Kor. J. Orient. Physiol. Pathol. 18, 1418-1425 (2004).
13. Gyamfi, M.A., Yonamine, M., and Aniya, Y., Free-radical scavenging action of medicinal herbs from Ghana: Thonningia sanguinea on experimentally-induced liver injuries. Gen. Pharmacol. 32, 661-667 (1999).
14. Halliwell, B., Free radicals, antioxidants, and human disease: curiosity, cause, or consequence. Lancet 344, 721-724 (1994).
15. Harman, D., Free radical involvement in aging-pathophysiology and therapeutic implications. Drugs Aging 3, 60-80 (1993).
16. Hasselmo, M.E., The role of acetylcholine in learning and memory. Curr. Opin. Neurobiol. 16, 710-715 (2006).
17. Hong, K.J., Lee, C.H., and Kim, S.W., Aspergillus oryzae GB-107 fermentation improves nutritional quality of food soybeans and feed soybean meals. J. Med. Food 7, 430-435 (2004).
18. Hsieh, M.T., Peng, W.H., Wu, C.R., and Wang, W.H., The ameliorating effects of the cognitive-enhancing Chinese herbs on scopolamine-induced amnesia in rats. Phytother. Res. 14, 375-377 (2000).
19. Hung, Y.H., Huang, H.Y., and Chou, C.C., Mutagenic and antimutagenic effects of methanol extracts of unfermented and fermented black soybeans. Int. J. Food Micmbiol. 118, 62-68 (2007).
20. Ibrahim, H.R., Hoq, M.I., and Aoki, T., Ovotransferrin possesses SOD-like superoxide anion scavenging activity that is promoted by copper and manganese binding. Int. J. Biol. Macromol. 41, 631-640 (2007).
21. Ikeya, Y., Takeda, S., Tunakawa, M., Karakida, H. Toda, K., Yamaguchi, T., and Aburada, M., Cognitive improving and cerebral protective effects of acylated oligosaccharides in Polygala tenuifolia. Biol. Pharm. Bull. 27, 1081-108 (2004).
22. Jeong, E.J., Lee, K.Y., Kim, S.H., Sung, S.H., and Kim, Y.C., Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice. Eur. J. Pharmacol. 588, 78-84 (2008).
23. Jung, I.C. and Lee, S.R., Effects of ChongMyung-Tang and MokguenpiChongMyung-Tang Extract on the Alzheimer's Disease Model Induced by CT105. Kor. J. Orient. Physiol. Pathol. 20, 394-403 (2006).
24. Kim, B.H., Kang, J.H., Lee, S.Y., Cho, H.J., Kim, Y.J., Kim, Y.J., and Ahn, S.C., Biotransformation of Ginseng to Compound K by Aspergillus oryzae. J. Life Sci. 16, 136-140 (2006).
25. Kim, D.G., Son, D.H., Choi, U.K., Cho, Y.S., and Kim, S.M., The antioxidant ability and nitrite scavenging ability of Poria cocos. J. Kor. Soc. Food Sci. Nutr. 31, 1097-1101 (2002).
26. Kim, K.Y., Kim, H.W., Lee, S.Y., Cha, D.Y., Lee, S.J., Kim, G.Y., Kim, H.J., and Jeong, H.W., Neuroprotective Effects of Gagam-ChongMeong-Tang on Cognitive Function after Ischemic Brain Injury in Rats. Kor. J. Orient. Physiol. Pathol. 22, 556-561 (2008).
27. Lee, L.H., Hung, Y.H., and Chou, C.C., Solid-state fermentation with fungi to enhance the antioxidative activity, total phenolic and anthocyanin contents of black bean. Int. J. Food Micmbiol. 121, 150-6 (2008).
28. Lee, S.H., Chang, G.T., and Kim, J.H., Effects of Chongmyung-tang on Learning and Memory Performances in Mice. Kor. J. Orient. Physiol. Pathol. 20, 471-476(2006).
29. Maxwell, S.R., Anti-oxidant therapy: does it have a role in the treatment of human disease? Expert Opin. Investig. Drugs. 6, 211-236 (1997).
30. Obón, J.M., Castellar, M.R., Cascales, J.A., and Fenández-López, J.A, Assessment of the TEAC method for determining the antioxidant capacity of synthetic red food colorants. Food Res. Internat. 38, 843-845 (2005).
31. Oh, M.H., Houghton, P.J., Whang, W.K., and Cho, J.H., Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity. Phytomedicine 11, 544-548 (2004).
32. Park, E.K., Shim, E.S., Jung, H.S., Sohn, N.W., and Sohn, Y.J., Effects of Chongmyung-tang, Polygalae Radix and Acori Graminei Rhizoma on A Toxicity and Memory Dysfunction in Mice. Kor. J. Orient. Int. Med. 29, 608-620 (2008).
33. Park, Y.K., Kang, B.S., Yun, E.K., Kang, S.I., Park, C.H., Lee, D.W., Ha, J.H., and Huh, K. Effects of Some Sedative Oriental Medicines on Neurotransmission and Antioxidative System in vitro. Yakhak Hoeji. 44, 22-28 (2000).
34. Sen, C.K. and Packer, L., Antioxidant and redox regulation of gene transcription, FASEB J. 10, 709-720 (1996).
35. Weingartner, H., Models of memory dysfunction. Ann. NY Acad. Sci. 444, 359-369 (1985).
36. Whitehouse, P.J., Price, D.L., Clark, A.W., Coyle, J.T., and DeLong, M.R., Alzheimer disease: evidence for selective loss of cholinergic neurons in the nucleus basalis. Ann. Neurol. 10, 122-126 (1981).
37. Xue, W., Hu, J.F., Yuan, Y.H., Sun, J.D., Li, B.Y., Zhang, D.M., Li, C.J., and Chen, N.H., Polygalasaponin XXXII from Polygala tenuifolia root improves hippocampal-dependent learning and memory. Acta Pharmacol Sin. 30, 1211-1219.(2009).
38. Yun, Y.J., Lee, B.B., Hahm, D.H., Kang, S.K., Han, S.M., Lee, H.J., Pyun, K.H., and Shim, L.S., Neuroprotective effect of palmulchongmyeong-tang on ischemia-induced learning and memory deficits in the rat. Biol. Pharmaceut. Bull. 30, 337-342 (2007).