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Volumn 30, Issue 8, 2011, Pages 1634-1644

Hydrophobicity as a driver of MHC class i antigen processing

Author keywords

degradation signal; ERAD; hydrophobicity; MHC class I peptides; transmembrane domain

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MEMBRANE PROTEIN;

EID: 79955010364     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.62     Document Type: Article
Times cited : (30)

References (50)
  • 2
    • 76149098224 scopus 로고    scopus 로고
    • Stringent requirement for HRD1, SEL1L, and OS-9/ XTP3-B for disposal of ERAD-LS substrates
    • Bernasconi R, Galli C, Calanca V, Nakajima T, Molinari M (2010) Stringent requirement for HRD1, SEL1L, and OS-9/ XTP3-B for disposal of ERAD-LS substrates. J Cell Biol 188: 223-235
    • (2010) J Cell Biol , vol.188 , pp. 223-235
    • Bernasconi, R.1    Galli, C.2    Calanca, V.3    Nakajima, T.4    Molinari, M.5
  • 3
    • 33746228127 scopus 로고    scopus 로고
    • Distinct Ubiquitin-Ligase Complexes Define Convergent Pathways for the Degradation of ER Proteins
    • DOI 10.1016/j.cell.2006.05.043, PII S0092867406008579
    • Carvalho P, Goder V, Rapoport TA (2006) Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. Cell 126: 361-373 (Pubitemid 44092963)
    • (2006) Cell , vol.126 , Issue.2 , pp. 361-373
    • Carvalho, P.1    Goder, V.2    Rapoport, T.A.3
  • 4
    • 0032529386 scopus 로고    scopus 로고
    • Antigen processing of two H2-IE(d)-restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein
    • Chianese-Bullock KA, Russell HI, Moller C, Gerhard W, Monaco JJ, Eisenlohr LC (1998) Antigen processing of two H2-IEd restricted epitopes is differentially influenced by the structural changes in a viral glycoprotein. J Immunol 161: 1599-1607 (Pubitemid 28387574)
    • (1998) Journal of Immunology , vol.161 , Issue.4 , pp. 1599-1607
    • Chianese-Bullock, K.A.1    Russell, H.I.2    Moller, C.3    Gerhard, W.4    Monaco, J.J.5    Eisenlohr, L.C.6
  • 5
    • 77949317182 scopus 로고    scopus 로고
    • Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase
    • Dolan BP, Li L, Takeda K, Bennink JR, Yewdell JW (2010) Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase. J Immunol 184: 1419-1424
    • (2010) J Immunol , vol.184 , pp. 1419-1424
    • Dolan, B.P.1    Li, L.2    Takeda, K.3    Bennink, J.R.4    Yewdell, J.W.5
  • 6
    • 34247585533 scopus 로고    scopus 로고
    • Rethinking peptide supply to MHC class I molecules
    • DOI 10.1038/nri2077, PII NRI2077
    • Eisenlohr LC, Huang L, Golovina TN (2007) Rethinking peptide supply to MHC class I molecules. Nat Rev Immunol 7: 403-410 (Pubitemid 46674491)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.5 , pp. 403-410
    • Eisenlohr, L.C.1    Huang, L.2    Golovina, T.N.3
  • 7
    • 0026599764 scopus 로고
    • Flanking sequences influence the presentation of an endogenously synthesized pep-tide to cytotoxic T lymphocytes
    • Eisenlohr LC, Yewdell JW, Bennink JR (1992) Flanking sequences influence the presentation of an endogenously synthesized pep-tide to cytotoxic T lymphocytes. J Exp Med 175: 481-487
    • (1992) J Exp Med , vol.175 , pp. 481-487
    • Eisenlohr, L.C.1    Yewdell, J.W.2    Bennink, J.R.3
  • 8
    • 0032555922 scopus 로고    scopus 로고
    • Major histocompatibility complex class I viral antigen processing in the secretory pathway defined by the trans-Golgi network protease furin
    • DOI 10.1084/jem.188.6.1105
    • Gil-Torregrosa BC, Raul Castano A, Del Val M (1998) Major histo-compatibility complex class I viral antigen processing in the secretory pathway defined by the trans-Golgi network protease furin. J Exp Med 188: 11 0 5 - 111 6 (Pubitemid 28443334)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.6 , pp. 1105-1116
    • Gil-Torregrosa, B.C.1    Castano, A.R.2    Del Val, M.3
  • 9
    • 0032525130 scopus 로고    scopus 로고
    • Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae
    • DOI 10.1093/emboj/17.10.2759
    • Gilon T, Chomsky O, Kulka RG (1998) Degradation signals for ubiquitin system proteolysis in Saccharomyces cerevisiae. EMBO J 17: 2759-2766 (Pubitemid 28227122)
    • (1998) EMBO Journal , vol.17 , Issue.10 , pp. 2759-2766
    • Gilon, T.1    Chomsky, O.2    Kulka, R.G.3
  • 10
    • 14044270751 scopus 로고    scopus 로고
    • The impact of misfolding versus targeted degradation on the efficiency of the MHC class I-restricted antigen processing
    • Golovina TN, Morrison SE, Eisenlohr LC (2005) The impact of mis-folding versus targeted degradation on the efficiency of the MHC class I-restricted antigen processing. J Immunol 174: 2763-2769 (Pubitemid 40279692)
    • (2005) Journal of Immunology , vol.174 , Issue.5 , pp. 2763-2769
    • Golovina, T.N.1    Morrison, S.E.2    Eisenlohr, L.C.3
  • 11
    • 0037087304 scopus 로고    scopus 로고
    • Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum
    • Golovina TN, Wherry EJ, Bullock TN, Eisenlohr LC (2002) Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum. J Immunol 168: 2667-2675 (Pubitemid 34211642)
    • (2002) Journal of Immunology , vol.168 , Issue.6 , pp. 2667-2675
    • Golovina, T.N.1    Wherry, E.J.2    Bullock, T.N.J.3    Eisenlohr, L.C.4
  • 13
    • 0029907090 scopus 로고    scopus 로고
    • Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen
    • DOI 10.1073/pnas.93.25.14692
    • Gueguen M, Long EO (1996) Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen. Proc Natl Acad Sci USA 93: 14692-14697 (Pubitemid 26419030)
    • (1996) Proceedings of the National Academy of Sciences of the United States of America , vol.93 , Issue.25 , pp. 14692-14697
    • Gueguen, M.1    Long, E.O.2
  • 14
    • 0028117314 scopus 로고
    • Molecular chaperones in protein folding: The art of avoiding sticky situations
    • DOI 10.1016/0968-0004(94)90169-4
    • Hartl F-U, Hlodan R, Langer T (1994) Molecular chaperones in protein folding: the art of avoiding sticky situations. Trends Biochem Sci 19: 20-25 (Pubitemid 24028727)
    • (1994) Trends in Biochemical Sciences , vol.19 , Issue.1 , pp. 20-25
    • Hartl, F.-U.1    Hlodan, R.2    Langer, T.3
  • 16
    • 0032563319 scopus 로고    scopus 로고
    • Degradation signal masking by heterodimerization of MATα2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway
    • DOI 10.1016/S0092-8674(00)81421-X
    • Johnson PR, Swanson R, Rakhilina L, Hochstrasser M (1998) Degradation signal masking by heterodimerization of MATalpha2 and MATa1 blocks their mutual destruction by the ubiquitin-proteasome pathway. Cell 94: 217-227 (Pubitemid 28348009)
    • (1998) Cell , vol.94 , Issue.2 , pp. 217-227
    • Johnson, P.R.1    Swanson, R.2    Rakhilina, L.3    Hochstrasser, M.4
  • 17
    • 33751333201 scopus 로고    scopus 로고
    • Substrate-Specific Translocational Attenuation during ER Stress Defines a Pre-Emptive Quality Control Pathway
    • DOI 10.1016/j.cell.2006.10.032, PII S0092867406014103
    • Kang SW, Rane NS, Kim SJ, Garrison JL, Taunton J, Hegde RS (2006) Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell 127: 999-1013 (Pubitemid 44803063)
    • (2006) Cell , vol.127 , Issue.5 , pp. 999-1013
    • Kang, S.-W.1    Rane, N.S.2    Kim, S.J.3    Garrison, J.L.4    Taunton, J.5    Hegde, R.S.6
  • 18
    • 0035886881 scopus 로고    scopus 로고
    • + T cell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway
    • DOI 10.1084/jem.194.8.1053
    • Lautscham G, Mayrhofer S, Taylor G, Haigh T, Leese A, Rickinson A, Blake N (2001) Processing of a multiple membrane spanning Epstein-Barr virus protein for CD8(+) Tcell recognition reveals a proteasome-dependent, transporter associated with antigen processing-independent pathway. J Exp Med 194: 1053-1068 (Pubitemid 32995777)
    • (2001) Journal of Experimental Medicine , vol.194 , Issue.8 , pp. 1053-1068
    • Lautscham, G.1    Mayrhofer, S.2    Taylor, G.3    Haigh, T.4    Leese, A.5    Rickinson, A.6    Blake, N.7
  • 19
    • 57749116223 scopus 로고    scopus 로고
    • Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery
    • Metzger MB, Maurer MJ, Dancy BM, Michaelis S (2008) Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery. J Biol Chem 283: 32302-32316
    • (2008) J Biol Chem , vol.283 , pp. 32302-32316
    • Metzger, M.B.1    Maurer, M.J.2    Dancy, B.M.3    Michaelis, S.4
  • 20
    • 23144451257 scopus 로고    scopus 로고
    • ERAD: The long road to destruction
    • DOI 10.1038/ncb0805-766
    • Meusser B, Hirsch C, Jarosch E, Sommer T (2005) ERAD: the long road to destruction. Nature Cell Biol 7: 766-772 (Pubitemid 41079045)
    • (2005) Nature Cell Biology , vol.7 , Issue.8 , pp. 766-772
    • Meusser, B.1    Hirsch, C.2    Jarosch, E.3    Sommer, T.4
  • 21
    • 14044265100 scopus 로고    scopus 로고
    • Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that misfolded full-length proteins are efficient substrates for class I processing and presentation
    • Ostankovitch M, Robila V, Engelhard VH (2005) Regulated folding of tyrosinase in the endoplasmic reticulum demonstrates that mis-folded full-length proteins are efficient substrates for class I processing and presentation. J Immunol 174: 2544-2551 (Pubitemid 40279667)
    • (2005) Journal of Immunology , vol.174 , Issue.5 , pp. 2544-2551
    • Ostankovitch, M.1    Robila, V.2    Engelhard, V.H.3
  • 22
    • 55849088319 scopus 로고    scopus 로고
    • Regulation of MHC class i assembly and peptide binding
    • Peaper DR, Cresswell P (2008) Regulation of MHC class I assembly and peptide binding. Annu Rev Cell Dev Biol 24: 343-368
    • (2008) Annu Rev Cell Dev Biol , vol.24 , pp. 343-368
    • Peaper, D.R.1    Cresswell, P.2
  • 23
    • 0030849769 scopus 로고    scopus 로고
    • Localization, quantitation, and in situ detection of specific peptide- MHC class I complexes using a monoclonal antibody
    • DOI 10.1016/S1074-7613(00)80447-1
    • Porgador A, Yewdell JW, Deng Y, Bennink JR, Germain RN (1997) Localization, quantitation, and in situ detection of specific peptide-MHC class I complexes using a monoclonal antibody. Immunity 6: 715-726 (Pubitemid 27305734)
    • (1997) Immunity , vol.6 , Issue.6 , pp. 715-726
    • Porgador, A.1    Yewdell, J.W.2    Deng, Y.3    Bennink, J.R.4    Germain, R.N.5
  • 25
    • 33745301876 scopus 로고    scopus 로고
    • Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products
    • Qian SB, Reits E, Neefjes J, Deslich JM, Bennink JR, Yewdell JW (2006) Tight linkage between translation and MHC class I peptide ligand generation implies specialized antigen processing for defective ribosomal products. J Immunol 177: 227-233 (Pubitemid 43939134)
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 227-233
    • Qian, S.-B.1    Reits, E.2    Neefjes, J.3    Deslich, J.M.4    Bennink, J.R.5    Yewdell, J.W.6
  • 26
    • 34247281027 scopus 로고    scopus 로고
    • Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequence
    • DOI 10.1074/jbc.M611436200
    • Raue U, Oellerer S, Rospert S (2007) Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequence. J Biol Chem 282: 7809-7816 (Pubitemid 47093553)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.11 , pp. 7809-7816
    • Raue, U.1    Oellerer, S.2    Rospert, S.3
  • 27
    • 0034643348 scopus 로고    scopus 로고
    • The major substrates for TAP in vivo are derived from newly synthesized proteins
    • DOI 10.1038/35008103
    • Reits EA, Vos JC, Gromme M, Neefjes J (2000) The major substrates for TAP in vivo are derived from newly synthesized proteins [see comments]. Nature 404: 774-778 (Pubitemid 30212406)
    • (2000) Nature , vol.404 , Issue.6779 , pp. 774-778
    • Reits, E.A.J.1    Vos, J.C.2    Gramme, M.3    Neefjes, J.4
  • 28
    • 24944446266 scopus 로고    scopus 로고
    • Endoplasmic reticulum-associated degradation
    • DOI 10.1146/annurev.cellbio.21.012704.133250
    • Romisch K (2005) Endoplasmic reticulum-associated degradation. Annu Rev Cell Dev Biol 21 : 435-456 (Pubitemid 41740642)
    • (2005) Annual Review of Cell and Developmental Biology , vol.21 , pp. 435-456
    • Romisch, K.1
  • 30
    • 0034643336 scopus 로고    scopus 로고
    • Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
    • DOI 10.1038/35008096
    • Schubert U, Anton LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR (2000) Rapid degradation of a large fraction of newly synthesized proteins by proteasomes [see comments]. Nature 404: 770-774 (Pubitemid 30212405)
    • (2000) Nature , vol.404 , Issue.6779 , pp. 770-774
    • Schubert, U.1    Anton, L.C.2    Gibbs, J.3    Norbury, C.C.4    Yewdell, J.W.5    Bennink, J.R.6
  • 31
    • 1842407159 scopus 로고    scopus 로고
    • Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing
    • DOI 10.1084/jem.186.7.1087
    • Snyder HL, Bacik I, Bennink JR, Kearns G, Behrens TW, Bachi T, Orlowski M, Yewdell JW (1997) Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing. J Exp Med 186: 1087-1098 (Pubitemid 27441152)
    • (1997) Journal of Experimental Medicine , vol.186 , Issue.7 , pp. 1087-1098
    • Snyder, H.L.1    Bacik, I.2    Bennink, J.R.3    Kearns, G.4    Behrens, T.W.5    Bachi, T.6    Orlowski, M.7    Yewdell, J.W.8
  • 32
    • 0344944630 scopus 로고    scopus 로고
    • Protein aggregation and aggregate toxicity: New insights into protein folding, misfolding diseases and biological evolution
    • DOI 10.1007/s00109-003-0464-5
    • Stefani M, Dobson CM (2003) Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution. J Mol Med 81: 678-699 (Pubitemid 37491594)
    • (2003) Journal of Molecular Medicine , vol.81 , Issue.11 , pp. 678-699
    • Stefani, M.1    Dobson, C.M.2
  • 33
    • 0033555390 scopus 로고    scopus 로고
    • Cutting edge: Induction of enhanced CTL-dependent protective immunity in vivo by N-end rule targeting of a model tumor antigen
    • Tobery T, Siliciano RF (1999) Induction of enhanced CTL-dependent protective immunity in vivo by N- end rule targeting of a model tumor antigen. J Immunol 162: 639-642 (Pubitemid 29035381)
    • (1999) Journal of Immunology , vol.162 , Issue.2 , pp. 639-642
    • Tobery, T.1    Siliciano, R.F.2
  • 34
    • 0030977234 scopus 로고    scopus 로고
    • Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization
    • DOI 10.1084/jem.185.5.909
    • Tobery TW, Siliciano RF (1997) Targeting of HIV-1 antigens for rapid intracellular degradation enhances cytotoxic T lymphocyte (CTL) recognition and the induction of de novo CTL responses in vivo after immunization. J Exp Med 185: 909-920 (Pubitemid 27119875)
    • (1997) Journal of Experimental Medicine , vol.185 , Issue.5 , pp. 909-920
    • Tobery, T.W.1    Siliciano, R.F.2
  • 35
    • 0024095276 scopus 로고
    • Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen
    • Townsend A, Bastin J, Gould K, Brownlee G, Andrew M, Coupar B, Boyle D, Chan S, Smith G (1988) Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. J Exp Med 168: 1211-1224
    • (1988) J Exp Med , vol.168 , pp. 1211-1224
    • Townsend, A.1    Bastin, J.2    Gould, K.3    Brownlee, G.4    Andrew, M.5    Coupar, B.6    Boyle, D.7    Chan, S.8    Smith, G.9
  • 36
    • 0022972506 scopus 로고
    • Cytotoxic T lymphocytes recognize influenza haemagglutinin that lacks a signal sequence
    • DOI 10.1038/324575a0
    • Townsend ARM, Bastin J, Gould K, Brownlee GG (1986) Cytotoxic T lymphocytes recognize influenza hemagglutinin that lacks a signal sequence. Nature 324: 575-577 (Pubitemid 17185072)
    • (1986) Nature , vol.324 , Issue.6097 , pp. 575-577
    • Townsend, A.R.M.1    Bastin, J.2    Gould, K.3    Brownlee, G.G.4
  • 37
    • 0034703437 scopus 로고    scopus 로고
    • Detecting and measuring cotrans-lational protein degradation in vivo
    • Turner GC, Varshavsky A (2000) Detecting and measuring cotrans-lational protein degradation in vivo. Science 289: 2117-2120
    • (2000) Science , vol.289 , pp. 2117-2120
    • Turner, G.C.1    Varshavsky, A.2
  • 38
    • 29344464782 scopus 로고    scopus 로고
    • Cell biology: Protein synthesis upon acute nutrient restriction relies on proteasome function
    • DOI 10.1126/science.1121925
    • Vabulas RM, Hartl FU (2005) Protein synthesis upon acute nutrient restriction relies on proteasome function. Science 310: 1960-1963 (Pubitemid 43005990)
    • (2005) Science , vol.310 , Issue.5756 , pp. 1960-1963
    • Vabulas, R.M.1    Hartl, F.U.2
  • 39
    • 0026766091 scopus 로고
    • The N-end rule
    • Varshavsky A (1992) The N-end rule. Cell 69: 725-735
    • (1992) Cell , vol.69 , pp. 725-735
    • Varshavsky, A.1
  • 40
    • 56749176947 scopus 로고    scopus 로고
    • One step at a time: Endoplasmic reticulum-associated degradation
    • Vembar SS, Brodsky JL (2008) One step at a time: endoplasmic reticulum-associated degradation. Nat Rev Mol Cell Biol 9: 944-957
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 944-957
    • Vembar, S.S.1    Brodsky, J.L.2
  • 41
    • 0021153961 scopus 로고
    • Intracellular protein degradation: Basis of a self-regulating mechanism for the proteolysis of endogenous proteins
    • Wheatley DN (1984) Intracellular protein degradation: basis of a self-regulating mechanism for the proteolysis of endogenous proteins. J Theor Biol 107: 127-149 (Pubitemid 14118252)
    • (1984) Journal of Theoretical Biology , vol.107 , Issue.1 , pp. 127-149
    • Wheatley, D.N.1
  • 42
    • 0019218158 scopus 로고
    • Kinetics of degradation of 'short-' and 'long-lived' proteins in cultured mammalian cells
    • DOI 10.1016/0309-1651(80)90045-4
    • Wheatley DN, Giddings MR, Inglis MS (1980) Kinetics of degradation of 'short-' and 'long-lived' proteins in cultured mammalian cells. Cell Biol Int Rep 4: 1081-1090 (Pubitemid 11221748)
    • (1980) Cell Biology International Reports , vol.4 , Issue.12 , pp. 1081-1090
    • Wheatley, D.N.1    Giddings, M.R.2    Inglis, M.S.3
  • 43
    • 0033214423 scopus 로고    scopus 로고
    • The induction of virus-specific CTL as a function of increasing epitope expression: Responses rise steadily until excessively high levels of epitope are attained
    • Wherry EJ, Puorro KA, Porgador A, Eisenlohr LC (1999) The induction of virus-specific CTL as a function of increasing epitope expression: responses rise steadily until excessively high levels of epitope are attained. J Immunol 163: 3735-3745 (Pubitemid 29450896)
    • (1999) Journal of Immunology , vol.163 , Issue.7 , pp. 3735-3745
    • Wherry, E.J.1    Puorro, K.A.2    Porgador, A.3    Eisenlohr, L.C.4
  • 44
    • 0033520987 scopus 로고    scopus 로고
    • Posttranslational quality control: Folding, refolding, and degrading proteins
    • Wickner S, Maurizi MR, Gottesman S (1999) Posttranslational quality control: folding, refolding, and degrading proteins. Science 286: 1888-1893 (Pubitemid 129515889)
    • (1999) Science , vol.286 , Issue.5446 , pp. 1888-1893
    • Wickner, S.1    Maurizi, M.R.2    Gottesman, S.3
  • 45
    • 4344657752 scopus 로고    scopus 로고
    • An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses
    • Wong SB, Buck CB, Shen X, Siliciano RF (2004) An evaluation of enforced rapid proteasomal degradation as a means of enhancing vaccine-induced CTL responses. J Immunol 173: 3073-3083 (Pubitemid 39142013)
    • (2004) Journal of Immunology , vol.173 , Issue.5 , pp. 3073-3083
    • Wong, S.B.J.1    Buck, C.B.2    Shen, X.3    Siliciano, R.F.4
  • 46
    • 33846117141 scopus 로고    scopus 로고
    • Plumbing the sources of endogenous MHC class I peptide ligands
    • DOI 10.1016/j.coi.2006.11.010, PII S0952791506002421, Innate immunity/Antigen processing and recognition
    • Yewdell JW (2007) Plumbing the sources of endogenous MHC class I peptide ligands. Curr Opin Immunol 19: 79-86 (Pubitemid 46073699)
    • (2007) Current Opinion in Immunology , vol.19 , Issue.1 , pp. 79-86
    • Yewdell, J.W.1
  • 47
    • 0030239693 scopus 로고    scopus 로고
    • Defective Ribosomal Products (DRiPs): A Major Source of Antigenic Peptides for MHC Class I Molecules?
    • Yewdell JW, Antón LC, Bennink JR (1996) Defective ribosomal products (DRIPs): a major source of antigenic peptides for MHC class I molecules? J Immunol 157: 1823-1826 (Pubitemid 126449651)
    • (1996) Journal of Immunology , vol.157 , Issue.5 , pp. 1823-1826
    • Yewdell, J.W.1    Anton, L.C.2    Bennink, J.R.3
  • 48
    • 33745833084 scopus 로고    scopus 로고
    • The DRiP hypothesis decennial: support, controversy, refinement and extension
    • DOI 10.1016/j.it.2006.06.008, PII S1471490606001785
    • Yewdell JW, Nicchitta CV (2006) The DRiP hypothesis decennial: support, controversy, refinement and extension. Trends Immunol 27: 368-373 (Pubitemid 44038666)
    • (2006) Trends in Immunology , vol.27 , Issue.8 , pp. 368-373
    • Yewdell, J.W.1    Nicchitta, C.V.2
  • 49
    • 0346521283 scopus 로고    scopus 로고
    • Making sense of mass destruction: Quantitating MHC class I antigen presentation
    • Yewdell JW, Reits E, Neefjes J (2003) Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol 3: 952-961 (Pubitemid 37521537)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.12 , pp. 952-961
    • Yewdell, J.W.1    Reits, E.2    Neefjes, J.3
  • 50
    • 33646867918 scopus 로고    scopus 로고
    • Epitopes derived by incidental translational frameshifting give rise to a protective CTL response
    • Zook MB, Howard MT, Sinnathamby G, Atkins JF, Eisenlohr LC (2006) Epitopes derived by incidental translational frameshifting give rise to a protective CTL response. J Immunol 176: 6928-6934 (Pubitemid 43787873)
    • (2006) Journal of Immunology , vol.176 , Issue.11 , pp. 6928-6934
    • Zook, M.B.1    Howard, M.T.2    Sinnathamby, G.3    Atkins, J.F.4    Eisenlohr, L.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.