Exercise training in ovariectomized rats stimulates estrogenic-like effects on expression of genes involved in lipid accumulation and subclinical inflammation in liver

Metabolism: Clinical and Experimental

Volumn 60, Issue 5, 2011, Pages 629-639

  Pighon, Abdolnaser ^a   Gutkowska, Jolanta ^b   Jankowski, Marek ^b   Rabasa Lhoret, Remi ^c   Lavoie, Jean Marc ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ACYL COENZYME A DESATURASE; CARBOHYDRATE RESPONSE ELEMENT BINDING PROTEIN; ESTRADIOL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MEMBRANE PROTEIN; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENDURANCE TRAINING; EXERCISE; FEMALE; GENE EXPRESSION; HEPATITIS; LIPID OXIDATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

EID: 79954997882     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2010.06.012     Document Type: Article

References (57)

1. Clark J.M. Weight loss as a treatment for nonalcoholic fatty liver disease J Clin Gastroenterol 40 Suppl 1 2006 S39 S43
2. Volzke H., Schwarz S., Baumeister S.E., Wallaschofski H., Schwahn C., and Grabe H.J. Menopausal status and hepatic steatosis in a general female population Gut 56 2007 594 595 (Pubitemid 46580520)
3. Kadowaki T., Hara K., Yamauchi T., Terauchi Y., Tobe K., and Nagai R. Molecular mechanism of insulin resistance and obesity Exp Biol Med (Maywood) 228 2003 1111 1117 (Pubitemid 37413667)
4. Stefan N., Kantartzis K., Machann J., Schick F., Thamer C., and Rittig K. Identification and characterization of metabolically benign obesity in humans Arch Intern Med 168 2008 1609 1616
5. Messier V, Karelis AD, Robillard ME, Bellefeuille P, Brochu M, Lavoie JM, et al. Metabolically healthy but obese individuals: relationship with hepatic enzymes. Metabolism Jan;59(1):20-4.
6. Pighon A., Paquette A., Barsalani R., Chapados N.A., Yasari S., and Doucet E. Substituting food restriction by resistance training prevents liver and body fat regain in ovariectomized rats Climacteric 12 2009 153 164
7. Paquette A., Shinoda M., Rabasa Lhoret R., Prud'homme D., and Lavoie J.M. Time course of liver lipid infiltration in ovariectomized rats: impact of a high-fat diet Maturitas 58 2007 182 190 (Pubitemid 47503634)
8. Deshaies Y., Dagnault A., Lalonde J., and Richard D. Interaction of corticosterone and gonadal steroids on lipid deposition in the female rat Am J Physiol 273 2 Pt 1 1997 E355 E362
9. Picard F., Deshaies Y., Lalonde J., Samson P., Labrie C., and Belanger A. Effects of the estrogen antagonist EM-652.HCl on energy balance and lipid metabolism in ovariectomized rats Int J Obes Relat Metab Disord 24 2000 830 840 (Pubitemid 30449918)
10. Paquette A., Wang D., Jankowski M., Gutkowska J., and Lavoie J.M. Effects of ovariectomy on PPAR alpha, SREBP-1c, and SCD-1 gene expression in the rat liver Menopause 15 2008 1169 1175
11. Toda K., Takeda K., Akira S., Saibara T., Okada T., and Onishi S. Alternations in hepatic expression of fatty-acid metabolizing enzymes in ArKO mice and their reversal by the treatment with 17beta-estradiol or a peroxisome proliferator J Steroid Biochem Mol Biol 79 2001 11 17 (Pubitemid 34158773)
12. Paquette A., Chapados N.A., Bergeron R., and Lavoie J.M. Fatty acid oxidation is decreased in the liver of ovariectomized rats Horm Metab Res 41 2009 511 515
13. Gauthier M.S., Couturier K., Latour J.G., and Lavoie J.M. Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis J Appl Physiol 94 2003 2127 2134 (Pubitemid 36605269)
14. Gauthier M.S., Couturier K., Charbonneau A., and Lavoie J.M. Effects of introducing physical training in the course of a 16-week high-fat diet regimen on hepatic steatosis, adipose tissue fat accumulation, and plasma lipid profile Int J Obes Relat Metab Disord 28 2004 1064 1071 (Pubitemid 38998714)
15. Corriveau P., Paquette A., Brochu M., Prud'homme D., Rabasa-Lhoret R., and Lavoie J.M. Resistance training prevents liver fat accumulation in ovariectomized rats Maturitas 59 2008 259 267
16. Pighon A., Paquette A., Barsalani R., Chapados N.A., Rabasa-Lhoret R., and Yasari S. Resistance training attenuates fat mass regain after weight loss in ovariectomized rats Maturitas 64 2009 52 57
17. Pighon A., Barsalani R., Yasari S., Prud'homme D., and Lavoie J.M. Does exercise training prior to ovariectomy protect against liver and adipocyte fat accumulation in rats? Climacteric 13 2010 238 248
18. Bruunsgaard H. Physical activity and modulation of systemic low-level inflammation J Leukoc Biol 78 2005 819 835 (Pubitemid 41384398)
19. Esposito K., and Giugliano D. The metabolic syndrome and inflammation: association or causation? Nutr Metab Cardiovasc Dis 14 2004 228 232 (Pubitemid 39611863)
20. Cai D., Yuan M., Frantz D.F., Melendez P.A., Hansen L., and Lee J. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB Nature medicine 11 2005 183 190 (Pubitemid 40321354)
21. Shoelson S.E., Lee J., and Goldfine A.B. Inflammation and insulin resistance J Clin Invest 116 2006 1793 1801 (Pubitemid 44033299)
22. Robertson M.C., Owens R.E., Klindt J., and Friesen H.G. Ovariectomy leads to a rapid increase in rat placental lactogen secretion Endocrinology 114 1984 1805 1811 (Pubitemid 14140337)
23. El-Mas M.M., and Abdel-Rahman A.A. Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability J Cardiovasc Pharmacol 43 2004 607 615 (Pubitemid 38534059)
24. Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., and Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419 (Pubitemid 15018832)
25. Barsalani R., Pighon A., Rabasa-Lhoret R., Yasari S., and Lavoie J.M. Liver of ovariectomized rats is resistant to resorption of lipids Physiol Behav 95 2008 216 221
26. Heine P.A., Taylor J.A., Iwamoto G.A., Lubahn D.B., and Cooke P.S. Increased adipose tissue in male and female estrogen receptor-alpha knockout mice Proc Natl Acad Sci U S A 97 2000 12729 12734
27. Donnelly K.L., Smith C.I., Schwarzenberg S.J., Jessurun J., Boldt M.D., and Parks E.J. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease J Clin Invest 115 2005 1343 1351 (Pubitemid 40629054)
28. Kohjima M., Enjoji M., Higuchi N., Kato M., Kotoh K., and Yoshimoto T. Re-evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease Int J Mol Med 20 2007 351 358
29. Cohen P., Ntambi J.M., and Friedman J.M. Stearoyl-CoA desaturase-1 and the metabolic syndrome Curr Drug Targets Immune Endocr Metabol Disord 3 2003 271 280
30. Cohen P., Miyazaki M., Socci N.D., Hagge-Greenberg A., Liedtke W., and Soukas A.A. Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss Science 297 2002 240 243 (Pubitemid 34761283)
31. Dentin R., Pegorier J.P., Benhamed F., Foufelle F., Ferre P., and Fauveau V. Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression J Biol Chem 279 2004 20314 20326 (Pubitemid 38623477)
32. Desvergne B., Michalik L., and Wahli W. Be fit or be sick: peroxisome proliferator-activated receptors are down the road Mol Endocrinol 18 2004 1321 1332 (Pubitemid 38692172)
33. Desvergne B., and Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocr Rev 20 1999 649 688 (Pubitemid 30650602)
34. Bjornstrom L., and Sjoberg M. Mechanisms of estrogen receptor signaling: convergence of genomic and nongenomic actions on target genes Mol Endocrinol 19 2005 833 842 (Pubitemid 40397050)
35. Kelly M.J., and Levin E.R. Rapid actions of plasma membrane estrogen receptors Trends Endocrinol Metab 12 2001 152 156 (Pubitemid 33713555)
36. Evinger A.J. III, and Levin E.R. Requirements for estrogen receptor alpha membrane localization and function Steroids 70 2005 361 363 (Pubitemid 40616033)
37. Revankar C.M., Cimino D.F., Sklar L.A., Arterburn J.B., and Prossnitz E.R. A transmembrane intracellular estrogen receptor mediates rapid cell signaling Science 307 2005 1625 1630 (Pubitemid 40354745)
38. D'Eon T.M., Souza S.C., Aronovitz M., Obin M.S., Fried S.K., and Greenberg A.S. Estrogen regulation of adiposity and fuel partitioning. Evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways J Biol Chem 280 2005 35983 35991 (Pubitemid 41633867)
39. Bajic V.B., Tan S.L., Chong A., Tang S., Strom A., and Gustafsson J.A. Dragon ERE Finder version 2: a tool for accurate detection and analysis of estrogen response elements in vertebrate genomes Nucleic Acids Res 31 2003 3605 3607 (Pubitemid 37448490)
40. Zhou G., Myers R., Li Y., Chen Y., Shen X., and Fenyk-Melody J. Role of AMP-activated protein kinase in mechanism of metformin action J Clin Invest 108 2001 1167 1174 (Pubitemid 32995375)
41. Winder W.W., and Thomson D.M. Cellular energy sensing and signaling by AMP-activated protein kinase Cell Biochem Biophys 47 2007 332 347 (Pubitemid 47339850)
42. Paquette A., Wang D., Gauthier M.S., Prud'homme D., Jankowski M., and Gutkowska J. Specific adaptations of estrogen receptor alpha and beta transcripts in liver and heart after endurance training in rats Mol Cell Biochem 306 2007 179 187 (Pubitemid 350001830)
43. Saengsirisuwan V., Pongseeda S., Prasannarong M., Vichaiwong K., and Toskulkao C. Modulation of insulin resistance in ovariectomized rats by endurance exercise training and estrogen replacement Metabolism 58 2009 38 47
44. Arkan M.C., Hevener A.L., Greten F.R., Maeda S., Li Z.W., and Long J.M. IKK-beta links inflammation to obesity-induced insulin resistance Nat Med 11 2005 191 198 (Pubitemid 40321355)
45. Chen H. Cellular inflammatory responses: novel insights for obesity and insulin resistance Pharmacol Res 53 2006 469 477 (Pubitemid 43767552)
46. Kireev R.A., Tresguerres A.C., Garcia C., Borras C., Ariznavarreta C., and Vara E. Hormonal regulation of pro-inflammatory and lipid peroxidation processes in liver of old ovariectomized female rats Biogerontology 11 2010 229 243
47. Hamilton K.L., Lin L., Wang Y., and Knowlton A.A. Effect of ovariectomy on cardiac gene expression: inflammation and changes in SOCS gene expression Physiol Genomics 32 2008 254 263 (Pubitemid 351186331)
48. Petersen A.M., and Pedersen B.K. The anti-inflammatory effect of exercise J Appl Physiol 98 2005 1154 1162 (Pubitemid 40396484)
49. Ksontini R., MacKay S.L., and Moldawer L.L. Revisiting the role of tumor necrosis factor alpha and the response to surgical injury and inflammation Arch Surg 133 1998 558 567 (Pubitemid 28224327)
50. Bolger A.P., Sharma R., von Haehling S., Doehner W., Oliver B., and Rauchhaus M. Effect of interleukin-10 on the production of tumor necrosis factor-alpha by peripheral blood mononuclear cells from patients with chronic heart failure Am J Cardiol 90 2002 384 389
51. Kaur K., Sharma A.K., Dhingra S., and Singal P.K. Interplay of TNF-alpha and IL-10 in regulating oxidative stress in isolated adult cardiac myocytes J Mol Cell Cardiol 41 2006 1023 1030 (Pubitemid 44791332)
52. Hashem R.M., Mahmoud M.F., El-Moselhy M.A., and Soliman H.M. Interleukin-10 to tumor necrosis factor-alpha ratio is a predictive biomarker in nonalcoholic fatty liver disease: interleukin-10 to tumor necrosis factor-alpha ratio in steatohepatitis Eur J Gastroenterol Hepatol 20 2008 995 1001
53. Pradhan A.D., Manson J.E., Rossouw J.E., Siscovick D.S., Mouton C.P., and Rifai N. Inflammatory biomarkers, hormone replacement therapy, and incident coronary heart disease: prospective analysis from the Women's Health Initiative observational study JAMA 288 2002 980 987 (Pubitemid 34920463)
54. Miller A.P., Chen Y.F., Xing D., Feng W., and Oparil S. Hormone replacement therapy and inflammation: interactions in cardiovascular disease Hypertension 42 2003 657 663 (Pubitemid 37237305)
55. Ridker P.M., Hennekens C.H., Rifai N., Buring J.E., and Manson J.E. Hormone replacement therapy and increased plasma concentration of C-reactive protein Circulation 100 1999 713 716 (Pubitemid 29383640)
56. Georgiadou P., and Sbarouni E. Effect of hormone replacement therapy on inflammatory biomarkers Adv Clin Chem 47 2009 59 93
57. Yang S.X., Diaz Padilla N., Zhu Q., Ma X.M., Sasso D., and Prestwood K. Estrogen replacement raises rat CRP without evidence of complement activation Endocr Res 31 2005 121 132 (Pubitemid 41759227)