Resting but not CpG stimulated keratinocytes suppress autologous T-helper cell proliferation - importance of PGE2 and T regulatory function

Experimental Dermatology

Volumn 20, Issue 5, 2011, Pages 394-400

  Kopfnagel, Verena ^a   Werfel, Thomas ^a   Wittmann, Miriam ^a,b  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

CpG; Epithelial cells; Human primary keratinocytes; Pathogen associated molecular patterns; T cell proliferation

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR FOXP3;

ARTICLE; CD4+ CD25+ T LYMPHOCYTE; CELL INTERACTION; CELL STIMULATION; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; HELPER CELL; HUMAN; HUMAN CELL; KERATINOCYTE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MICROENVIRONMENT; PROSTAGLANDIN SYNTHESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE;

ALPROSTADIL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; DINOPROSTONE; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMMUNE TOLERANCE; INDOMETHACIN; INTERFERON-GAMMA; INTERLEUKIN-10; KERATINOCYTES; LYMPHOCYTE ACTIVATION; OLIGODEOXYRIBONUCLEOTIDES; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTOR 9; TOLL-LIKE RECEPTORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 79954816880     PISSN: 09066705     EISSN: 16000625     Source Type: Journal    
DOI: 10.1111/j.1600-0625.2010.01220.x     Document Type: Article

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