메뉴 건너뛰기




Volumn 31, Issue 3, 2011, Pages 427-435

Evaluation of radioprotective efficacy and possible mechanism of action of Aloe gel

Author keywords

Aloe gel; Effective dose; Mortality; Radiation; Radiation sickness; Scavenging activity

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2,2' AZINOBIS(3 ETHYLBENZOTHIAZOLINE 6 SULFONIC ACID); ALOE VERA EXTRACT; ASCORBIC ACID; FREE RADICAL; GLUTATHIONE; NITRIC OXIDE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 79954800353     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2011.02.004     Document Type: Article
Times cited : (23)

References (56)
  • 1
    • 0032111029 scopus 로고    scopus 로고
    • Aloe vera: magic or medicine?
    • Atherton P. Aloe vera: magic or medicine?. Nurs. Stand. 1998, 12:49-54.
    • (1998) Nurs. Stand. , vol.12 , pp. 49-54
    • Atherton, P.1
  • 3
    • 79954975940 scopus 로고
    • La cystamine, protecteus par voie orale contre Le rayonnment x
    • Bacq Z.M. La cystamine, protecteus par voie orale contre Le rayonnment x. Bull. Acad. Med. Belg. 1953, 18:426-435.
    • (1953) Bull. Acad. Med. Belg. , vol.18 , pp. 426-435
    • Bacq, Z.M.1
  • 4
    • 11244258947 scopus 로고    scopus 로고
    • Radioprotective effect of abana, a polyherbal drug following total body irradiation
    • Baliga M.S., Jagetia G.C., Venkatesh P., Reddy R., Ulloor J. Radioprotective effect of abana, a polyherbal drug following total body irradiation. Br. J. Radiol. 2004, 77:1027-1035.
    • (2004) Br. J. Radiol. , vol.77 , pp. 1027-1035
    • Baliga, M.S.1    Jagetia, G.C.2    Venkatesh, P.3    Reddy, R.4    Ulloor, J.5
  • 5
    • 73649194769 scopus 로고
    • Improved method for the determination of blood glutathione
    • Beutler E., Duron O., Kelly B.M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 1963, 61:882-888.
    • (1963) J. Lab. Clin. Med. , vol.61 , pp. 882-888
    • Beutler, E.1    Duron, O.2    Kelly, B.M.3
  • 6
    • 34547667387 scopus 로고    scopus 로고
    • Healing property of the Piper betal phenol, allylpyrocatechol against indomethacin induced stomach ulceration and mechanism of action
    • Bhattacharya S., Banerjee D., Bauri A.K., Chattopadhyay S., Bandyopadhyay S.K. Healing property of the Piper betal phenol, allylpyrocatechol against indomethacin induced stomach ulceration and mechanism of action. World J. Gastroenterol. 2007, 13:3705-3713.
    • (2007) World J. Gastroenterol. , vol.13 , pp. 3705-3713
    • Bhattacharya, S.1    Banerjee, D.2    Bauri, A.K.3    Chattopadhyay, S.4    Bandyopadhyay, S.K.5
  • 7
    • 53249109543 scopus 로고    scopus 로고
    • Antioxidative effect of Aloe vera leaf extract against radiation induced oxidative stress
    • Bhaya S., Saini M.R. Antioxidative effect of Aloe vera leaf extract against radiation induced oxidative stress. Pharmacologyonline 2008, 2:671-682.
    • (2008) Pharmacologyonline , vol.2 , pp. 671-682
    • Bhaya, S.1    Saini, M.R.2
  • 8
    • 0344929414 scopus 로고
    • Selenium and vitamin E inhibit radiogenic and chemically induced transformation in vitro via different mechanisms
    • Borek C., Ong A., Mason H., Donahue L., Biaglow J. Selenium and vitamin E inhibit radiogenic and chemically induced transformation in vitro via different mechanisms. Proc. Natl. Acad. Sci. U.S.A. 1986, 83:1490-1494.
    • (1986) Proc. Natl. Acad. Sci. U.S.A. , vol.83 , pp. 1490-1494
    • Borek, C.1    Ong, A.2    Mason, H.3    Donahue, L.4    Biaglow, J.5
  • 9
    • 0001760557 scopus 로고    scopus 로고
    • Anti-diabetic activity of Aloe vera juice. Clinical trial in diabetes mellitus patients in combination with glibenclamide
    • Bunyapraphtsara N., Yongchaiyudha S., Rungpitarangsi V., Chokechaijaroen porn O. Anti-diabetic activity of Aloe vera juice. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine 1996, 3:245-248.
    • (1996) Phytomedicine , vol.3 , pp. 245-248
    • Bunyapraphtsara, N.1    Yongchaiyudha, S.2    Rungpitarangsi, V.3    Chokechaijaroen porn, O.4
  • 10
    • 0020580167 scopus 로고
    • Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membrane?
    • Burton G.W., Joyce A., Ingold K.U. Is vitamin E the only lipid-soluble, chain-breaking antioxidant in human blood plasma and erythrocyte membrane?. Arch. Biochem. Biophys. 1983, 221:281-290.
    • (1983) Arch. Biochem. Biophys. , vol.221 , pp. 281-290
    • Burton, G.W.1    Joyce, A.2    Ingold, K.U.3
  • 11
    • 0018776894 scopus 로고
    • Hydroperoxide metabolism in mammalian organs
    • Chance B., Sies H., Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol. Rev. 1979, 59:527.
    • (1979) Physiol. Rev. , vol.59 , pp. 527
    • Chance, B.1    Sies, H.2    Boveris, A.3
  • 12
    • 0031883730 scopus 로고    scopus 로고
    • Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats
    • Chithra P., Sajithlal G.B., Chandrakasan G. Influence of Aloe vera on collagen characteristics in healing dermal wounds in rats. Mol. Cell Biochem. 1998, 181:71-76.
    • (1998) Mol. Cell Biochem. , vol.181 , pp. 71-76
    • Chithra, P.1    Sajithlal, G.B.2    Chandrakasan, G.3
  • 13
    • 0015610134 scopus 로고
    • Effect Of dietary vitamin E on the activities of glutathione peroxidase system in rat tissues
    • Chow C.K., Reddy K., Tuppel A.L.L. Effect Of dietary vitamin E on the activities of glutathione peroxidase system in rat tissues. Nutr. J. 1973, 103:618-624.
    • (1973) Nutr. J. , vol.103 , pp. 618-624
    • Chow, C.K.1    Reddy, K.2    Tuppel, A.L.L.3
  • 14
    • 0022669805 scopus 로고
    • Antiarthritic activity of anthraquinons found in Aloe for podiatric medicine
    • Davis R.H., Agnew P.S., Shapiro E. Antiarthritic activity of anthraquinons found in Aloe for podiatric medicine. J. Am. Podiatr. Med. Assoc. 1986, 76:61-66.
    • (1986) J. Am. Podiatr. Med. Assoc. , vol.76 , pp. 61-66
    • Davis, R.H.1    Agnew, P.S.2    Shapiro, E.3
  • 15
    • 0031459669 scopus 로고    scopus 로고
    • Prooxidant and antioxidant reaction mechanism of carotene and radical interaction with vitamin E and C
    • Edge R., Truscott T.G. Prooxidant and antioxidant reaction mechanism of carotene and radical interaction with vitamin E and C. Nutrition 1997, 13:992-994.
    • (1997) Nutrition , vol.13 , pp. 992-994
    • Edge, R.1    Truscott, T.G.2
  • 16
    • 67549098433 scopus 로고    scopus 로고
    • Radioprotective effects of Aloe vera leaf extract on Swiss albino mice against whole body gamma radiation
    • Goyal P.K., Gehlot P. Radioprotective effects of Aloe vera leaf extract on Swiss albino mice against whole body gamma radiation. J. Environ. Pathol. Toxicol. Oncol. 2009, 28(1):53-61.
    • (2009) J. Environ. Pathol. Toxicol. Oncol. , vol.28 , Issue.1 , pp. 53-61
    • Goyal, P.K.1    Gehlot, P.2
  • 17
    • 0032786631 scopus 로고    scopus 로고
    • Reactive oxygen species: the unavoidable environmental insults
    • Gracy R.W., Talent J.M., Kong Y., Conard C.C. Reactive oxygen species: the unavoidable environmental insults. Mutat. Res. 1999, 428:17-22.
    • (1999) Mutat. Res. , vol.428 , pp. 17-22
    • Gracy, R.W.1    Talent, J.M.2    Kong, Y.3    Conard, C.C.4
  • 19
    • 0027354319 scopus 로고
    • Free radical involvement in aging pathophysiology and therapeutic implication
    • Harman D. Free radical involvement in aging pathophysiology and therapeutic implication. Drugs Ageing 1993, 3:60-80.
    • (1993) Drugs Ageing , vol.3 , pp. 60-80
    • Harman, D.1
  • 20
    • 4444317344 scopus 로고    scopus 로고
    • Quality and safety assurance in the processing of Aloe vera gel juice
    • He Q., Changhong L., Kojo E., Tian Z. Quality and safety assurance in the processing of Aloe vera gel juice. Food Control 2005, 16:95-104.
    • (2005) Food Control , vol.16 , pp. 95-104
    • He, Q.1    Changhong, L.2    Kojo, E.3    Tian, Z.4
  • 22
    • 0344850315 scopus 로고
    • An updated review of Aloe vera
    • Henry R. An updated review of Aloe vera. Cosmet. Toilet 1979, 94:42-50.
    • (1979) Cosmet. Toilet , vol.94 , pp. 42-50
    • Henry, R.1
  • 23
    • 0021228654 scopus 로고
    • Augmentation of natural cell mediated cytotoxic reactivity of mouse lymphoid cells by aloctin A
    • Imanishi K., Suzuki I. Augmentation of natural cell mediated cytotoxic reactivity of mouse lymphoid cells by aloctin A. Int. J Immunopharmacol. 1984, 6:539-543.
    • (1984) Int. J Immunopharmacol. , vol.6 , pp. 539-543
    • Imanishi, K.1    Suzuki, I.2
  • 24
    • 61849181012 scopus 로고    scopus 로고
    • Protective effect of an extract of Emblica officinalis against radiation induced damage in mice
    • Jindal A., Soyal D., Sharma A., Goyal P.K. Protective effect of an extract of Emblica officinalis against radiation induced damage in mice. Integr. Cancer Ther. 2009, 8:98-105.
    • (2009) Integr. Cancer Ther. , vol.8 , pp. 98-105
    • Jindal, A.1    Soyal, D.2    Sharma, A.3    Goyal, P.K.4
  • 25
    • 1642409438 scopus 로고    scopus 로고
    • Modulations of Bc12/Bax family were involved in chemopreventive effects of licorice root (Glycyrrhiza uralensis fisch) in MCF-7 human breast cancer cells
    • Jo E.H., Hong H.D., Ahn N.C., Jung J.W., Yang S.R., Park J.S., Kim S.H., Lee Y.S., Kang K.S. Modulations of Bc12/Bax family were involved in chemopreventive effects of licorice root (Glycyrrhiza uralensis fisch) in MCF-7 human breast cancer cells. J. Agric. Food Chem. 2004, 52:1715-1719.
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 1715-1719
    • Jo, E.H.1    Hong, H.D.2    Ahn, N.C.3    Jung, J.W.4    Yang, S.R.5    Park, J.S.6    Kim, S.H.7    Lee, Y.S.8    Kang, K.S.9
  • 27
    • 0031683515 scopus 로고    scopus 로고
    • Modifying effect of vitamins C, E and beta-carotene against gamma-ray induced DNA damage in mouse cells
    • Konopacka M., Widel M., Rzeszowska-Wolny J. Modifying effect of vitamins C, E and beta-carotene against gamma-ray induced DNA damage in mouse cells. Mutat. Res. 1998, 417:85-94.
    • (1998) Mutat. Res. , vol.417 , pp. 85-94
    • Konopacka, M.1    Widel, M.2    Rzeszowska-Wolny, J.3
  • 28
    • 0342398884 scopus 로고    scopus 로고
    • Effect of 'Rasayannas', herbal drug preparation on immune responses and its significance in cancer treatment
    • Kumar P.V., Kuttan R., Kuttan G. Effect of 'Rasayannas', herbal drug preparation on immune responses and its significance in cancer treatment. Ind. J. Exp. Biol. 1999, 37:27-31.
    • (1999) Ind. J. Exp. Biol. , vol.37 , pp. 27-31
    • Kumar, P.V.1    Kuttan, R.2    Kuttan, G.3
  • 29
    • 2142776019 scopus 로고
    • Aloe vera in cosmetics
    • Leung A.Y. Aloe vera in cosmetics. Drug Cosmet. Ind. 1977, 120:154-155.
    • (1977) Drug Cosmet. Ind. , vol.120 , pp. 154-155
    • Leung, A.Y.1
  • 30
    • 36248978668 scopus 로고    scopus 로고
    • Studies on the protective effects of Boerhaavia diffusa L. against gamma radiation-induced damage in mice
    • Manu K.A., Leyon P.V., Kuttan G. Studies on the protective effects of Boerhaavia diffusa L. against gamma radiation-induced damage in mice. Integr. Cancer Ther. 2007, 6(4):381-388.
    • (2007) Integr. Cancer Ther. , vol.6 , Issue.4 , pp. 381-388
    • Manu, K.A.1    Leyon, P.V.2    Kuttan, G.3
  • 31
    • 0017128027 scopus 로고
    • Effect of vitamin E deficiency on level of superoxide dismutase, glutathione peroxidase, catalase and lipid peroxide in rat liver
    • Masugi F., Nakamura T. Effect of vitamin E deficiency on level of superoxide dismutase, glutathione peroxidase, catalase and lipid peroxide in rat liver. Int. J. Vitam. Nutr. Res. 1976, 46:187-191.
    • (1976) Int. J. Vitam. Nutr. Res. , vol.46 , pp. 187-191
    • Masugi, F.1    Nakamura, T.2
  • 33
    • 0018384650 scopus 로고
    • Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction
    • Ohkhawa H., Oshishi N., Yogi K. Assay for lipid peroxidation in animal tissue by thiobarbituric acid reaction. Anal. Biochem. 1979, 95:351-358.
    • (1979) Anal. Biochem. , vol.95 , pp. 351-358
    • Ohkhawa, H.1    Oshishi, N.2    Yogi, K.3
  • 34
    • 0001793256 scopus 로고
    • Vitamin C and redox cyclic antioxidants
    • Marcel Dekker Inc., New York, L. Packer, J. Fuchs (Eds.)
    • Packer L. Vitamin C and redox cyclic antioxidants. Vitamin C in Health and Disease 1977, 95. Marcel Dekker Inc., New York. L. Packer, J. Fuchs (Eds.).
    • (1977) Vitamin C in Health and Disease , pp. 95
    • Packer, L.1
  • 35
    • 0026688491 scopus 로고
    • β-carotene and α-tocopherol are synergistic antioxidants
    • Palozza P., Krinsky N.I. β-carotene and α-tocopherol are synergistic antioxidants. Arch. Biochem. Biophys. 1992, 297:184-187.
    • (1992) Arch. Biochem. Biophys. , vol.297 , pp. 184-187
    • Palozza, P.1    Krinsky, N.I.2
  • 36
    • 0032427978 scopus 로고    scopus 로고
    • Radioprotective efficacy of Aloe vera leaf extract
    • Pande S., Kumar M., Kumar A. Radioprotective efficacy of Aloe vera leaf extract. Pharm. Biol. 1998, 36:1-6.
    • (1998) Pharm. Biol. , vol.36 , pp. 1-6
    • Pande, S.1    Kumar, M.2    Kumar, A.3
  • 40
    • 0019984745 scopus 로고
    • Myth, magic, witchcraft or fact? Aloe vera revisited
    • Robson M., Heggers J., Hangston W. Myth, magic, witchcraft or fact? Aloe vera revisited. J. Burn Care Rehabil. 1982, 3:157-162.
    • (1982) J. Burn Care Rehabil. , vol.3 , pp. 157-162
    • Robson, M.1    Heggers, J.2    Hangston, W.3
  • 41
    • 0000399955 scopus 로고
    • The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenyl hydrazine derivative of dehydroascorbic acid
    • Roe J.H., Kuether C.A. The determination of ascorbic acid in whole blood and urine through the 2,4-dinitrophenyl hydrazine derivative of dehydroascorbic acid. J. Biol. Chem. 1943, 147:399-407.
    • (1943) J. Biol. Chem. , vol.147 , pp. 399-407
    • Roe, J.H.1    Kuether, C.A.2
  • 42
    • 0346366651 scopus 로고    scopus 로고
    • Effectiveness of Aloe vera on the antioxidative status of different tissues in irradiated rats
    • Saada H.N., Ussama Z.S., Mahdy A.M. Effectiveness of Aloe vera on the antioxidative status of different tissues in irradiated rats. Pharmazie 2003, 58:929-931.
    • (2003) Pharmazie , vol.58 , pp. 929-931
    • Saada, H.N.1    Ussama, Z.S.2    Mahdy, A.M.3
  • 43
    • 0027749416 scopus 로고
    • Isoenzymes of superoxide dismutase from Aloe vera
    • Sabeh F., Wright T., Norton S.J. Isoenzymes of superoxide dismutase from Aloe vera. Enzyme Protein 1993, 47:92-98.
    • (1993) Enzyme Protein , vol.47 , pp. 92-98
    • Sabeh, F.1    Wright, T.2    Norton, S.J.3
  • 44
    • 77953337571 scopus 로고    scopus 로고
    • Anti-tumor activity of Aloe vera against DMBA/croton oil induced skin papillomagenesis in Swiss albino mice
    • Saini M.R., Goyal P.K., Chaudhary G. Anti-tumor activity of Aloe vera against DMBA/croton oil induced skin papillomagenesis in Swiss albino mice. J. Environ. Pathol. Toxicol. Oncol. 2010, 29(2):127-135.
    • (2010) J. Environ. Pathol. Toxicol. Oncol. , vol.29 , Issue.2 , pp. 127-135
    • Saini, M.R.1    Goyal, P.K.2    Chaudhary, G.3
  • 45
    • 0021947160 scopus 로고
    • Late effects of whole body irradiation on the pheripheral blood of mice and its modification by Liv 52
    • Saini M.R., Kumar S., Uma devi P., Saini N. Late effects of whole body irradiation on the pheripheral blood of mice and its modification by Liv 52. Radiobiol. Radiother. 1985, 26:487-490.
    • (1985) Radiobiol. Radiother. , vol.26 , pp. 487-490
    • Saini, M.R.1    Kumar, S.2    Uma devi, P.3    Saini, N.4
  • 46
    • 34248388570 scopus 로고    scopus 로고
    • Rajgira leaf extract prevents intestinal mucosa against radiation induced oxidative stress: a quantitative study
    • Saini M.R., Maharwal J. Rajgira leaf extract prevents intestinal mucosa against radiation induced oxidative stress: a quantitative study. Pharmacologyonline 2007, 1:113-124.
    • (2007) Pharmacologyonline , vol.1 , pp. 113-124
    • Saini, M.R.1    Maharwal, J.2
  • 47
    • 0026034897 scopus 로고
    • Studies on chemical protectors against radiation. XXXI. Protective mechanism of various compounds against skin injury induced by radiation
    • Sato Y. Studies on chemical protectors against radiation. XXXI. Protective mechanism of various compounds against skin injury induced by radiation. Yakugaku Zasshi 1991, 111:51-58.
    • (1991) Yakugaku Zasshi , vol.111 , pp. 51-58
    • Sato, Y.1
  • 48
    • 0017182932 scopus 로고
    • Effects of dietary selenium and tocopherol on glutathione peroxidase and superoxide dismutatase activities in rat phagocyte
    • Serfass R.E., Ganther H.E. Effects of dietary selenium and tocopherol on glutathione peroxidase and superoxide dismutatase activities in rat phagocyte. Life Sci. 1976, 19:1139-1144.
    • (1976) Life Sci. , vol.19 , pp. 1139-1144
    • Serfass, R.E.1    Ganther, H.E.2
  • 49
    • 0026330047 scopus 로고
    • Aloe vera. Its chemical and therapeutic properties
    • Shelton R.S. Aloe vera. Its chemical and therapeutic properties. Int. J. Dermatol. 1991, 30:679-683.
    • (1991) Int. J. Dermatol. , vol.30 , pp. 679-683
    • Shelton, R.S.1
  • 50
    • 37449012051 scopus 로고    scopus 로고
    • Aloe vera protects radiation induced DNA damage in mouse
    • Shekhawat R., Saini D.K., Saini M.R. Aloe vera protects radiation induced DNA damage in mouse. Pharmacologyonline 2007, 3:39-51.
    • (2007) Pharmacologyonline , vol.3 , pp. 39-51
    • Shekhawat, R.1    Saini, D.K.2    Saini, M.R.3
  • 51
    • 79954886912 scopus 로고    scopus 로고
    • Investigation on the role of beta carotene against radiation induced apoptosis. Ph.D. Thesis. University of Rajasthan, Jaipur, India.
    • Shrivastava, P., 2002. Investigation on the role of beta carotene against radiation induced apoptosis. Ph.D. Thesis. University of Rajasthan, Jaipur, India.
    • (2002)
    • Shrivastava, P.1
  • 52
    • 0031033145 scopus 로고    scopus 로고
    • Nitric oxide scavenging by curcuminoids
    • Sreejayan
    • Sreejayan, Rao M.N. Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 1997, 49:105-107.
    • (1997) J. Pharm. Pharmacol. , vol.49 , pp. 105-107
    • Rao, M.N.1
  • 53
    • 0014345208 scopus 로고
    • In "Combined Surgical and Radiation injury" III. The effect of preirradiation radioprotective drug treatment
    • Stromberg L.R., Mclaughlin M.M., Donati R.M. In "Combined Surgical and Radiation injury" III. The effect of preirradiation radioprotective drug treatment. Proc. Soc. Exp. Biol. Med. 1968, 129:140-143.
    • (1968) Proc. Soc. Exp. Biol. Med. , vol.129 , pp. 140-143
    • Stromberg, L.R.1    Mclaughlin, M.M.2    Donati, R.M.3
  • 55
    • 0032176834 scopus 로고    scopus 로고
    • Acemannan, hydrogel dressing versus saline dressing for pressure ulcers
    • Thomas D.R., Goode P.S., Lamaster K., Tennyson T. Acemannan, hydrogel dressing versus saline dressing for pressure ulcers. Adv. Wound Care 1998, 11:273-276.
    • (1998) Adv. Wound Care , vol.11 , pp. 273-276
    • Thomas, D.R.1    Goode, P.S.2    Lamaster, K.3    Tennyson, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.