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Volumn 117, Issue 15, 2011, Pages

High-resolution kinetics of cytokine signaling in human CD34/CD117-positive cells in unfractionated bone marrow

Author keywords

[No Author keywords available]

Indexed keywords

CD34 ANTIGEN; FLT3 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 3; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN S6; STAT5 PROTEIN; STEM CELL FACTOR RECEPTOR;

EID: 79954612135     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-10-316224     Document Type: Article
Times cited : (19)

References (36)
  • 1
    • 77953896432 scopus 로고    scopus 로고
    • Cell signaling by receptor tyrosine kinases
    • Lemmon MA, Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 2010;141 (7): 1117-1134.
    • (2010) Cell. , vol.141 , Issue.7 , pp. 1117-1134
    • Lemmon, M.A.1    Schlessinger, J.2
  • 2
    • 24944560467 scopus 로고    scopus 로고
    • Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations
    • DOI 10.1002/cyto.a.20167
    • Chow S, Hedley D, Grom P, Magari R, Jacobberger JW, Shankey TV. Whole blood fixation and permeabilization protocol with red blood cell lysis for flow cytometry of intracellular phosphorylated epitopes in leukocyte subpopulations. Cytometry A. 2005;67(1):4-17. (Pubitemid 41318288)
    • (2005) Cytometry Part A , vol.67 , Issue.1 , pp. 4-17
    • Chow, S.1    Hedley, D.2    Grom, P.3    Magari, R.4    Jacobberger, J.W.5    Shankey, T.V.6
  • 3
    • 0031818411 scopus 로고    scopus 로고
    • Flow cytometric analysis of protein phosphorylation in the hematopoetic system
    • Muller C, Bonmann M, Cassens U, Koch OM. Flow cytometric analysis of protein phosphorylation in the hematopoietic system. Leuk Lymphoma. 1998;29(3):351-360. (Pubitemid 28282331)
    • (1998) Leukemia and Lymphoma , vol.29 , Issue.3-4 , pp. 351-360
    • Muller, C.1    Bonmann, M.2    Cassens, U.3    Koch, O.M.4
  • 5
    • 0035870575 scopus 로고    scopus 로고
    • Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: Potential for pharmacodynamic monitoring of signal transduction inhibitors
    • DOI 10.1002/cyto.1067
    • Chow S, Patel H, Hedley DW. Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors. Cytometry. 2001;46(2):72-78. (Pubitemid 32423456)
    • (2001) Communications in Clinical Cytometry , vol.46 , Issue.2 , pp. 72-78
    • Chow, S.1    Patel, H.2    Hedley, D.W.3
  • 6
    • 0034874691 scopus 로고    scopus 로고
    • Detection of intracellular phosphorylated STAT-4 by flow cytometry
    • Uzel G, Frucht DM, Fleisher TA, Holland SM. Detection of intracellular phosphorylated STAT-4 by flow cytometry. Clin Immunol. 2001;100(3):270-276.
    • (2001) Clin. Immunol. , vol.100 , Issue.3 , pp. 270-276
    • Uzel, G.1    Frucht, D.M.2    Fleisher, T.A.3    Holland, S.M.4
  • 7
    • 0036173143 scopus 로고    scopus 로고
    • Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry
    • DOI 10.1038/nbt0202-155
    • Perez OD, Nolan GP. Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry. Nat Biotechnol. 2002;20(2):155-162. (Pubitemid 34158031)
    • (2002) Nature Biotechnology , vol.20 , Issue.2 , pp. 155-162
    • Perez, O.D.1    Nolan, G.P.2
  • 9
    • 34547202520 scopus 로고    scopus 로고
    • Targeting receptor tyrosine kinase signaling in acute myeloid leukemia
    • DOI 10.1016/j.critrevonc.2007.05.005, PII S1040842807001102
    • Doepfner KT, Boller D, Arcaro A. Targeting receptor tyrosine kinase signaling in acute myeloid leukemia. Crit Rev Oncol Hematol. 2007;63(3):215-230. (Pubitemid 47126864)
    • (2007) Critical Reviews in Oncology/Hematology , vol.63 , Issue.3 , pp. 215-230
    • Doepfner, K.T.1    Boller, D.2    Arcaro, A.3
  • 11
    • 84856016252 scopus 로고    scopus 로고
    • Insights into molecular pathways for targeted therapeutics in acute leukaemia
    • Stavropoulou V, Brault L, Schwaller J. Insights into molecular pathways for targeted therapeutics in acute leukaemia. Swiss Med Wkly. 2010;140: w13068.
    • (2010) Swiss Med. Wkly , vol.140
    • Stavropoulou, V.1    Brault, L.2    Schwaller, J.3
  • 13
    • 63549132657 scopus 로고    scopus 로고
    • Clinical implications of c-Kit mutations in acute myelogenous leukemia
    • Malaise M, Steinbach D, Corbacioglu S. Clinical implications of c-Kit mutations in acute myelogenous leukemia. Curr Hematol Malig Rep. 2009;4(2):77-82.
    • (2009) Curr. Hematol Malig Rep. , vol.4 , Issue.2 , pp. 77-82
    • Malaise, M.1    Steinbach, D.2    Corbacioglu, S.3
  • 14
    • 33744457653 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase/ Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia
    • DOI 10.1038/sj.leu.2404245, PII 2404245
    • Martelli AM, Nyakern M, Tabellini G, et al. Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. Leukemia. 2006;20(6):911-928. (Pubitemid 43797279)
    • (2006) Leukemia , vol.20 , Issue.6 , pp. 911-928
    • Martelli, A.M.1    Nyakern, M.2    Tabellini, G.3    Bortul, R.4    Tazzari, P.L.5    Evangelisti, C.6    Cocco, L.7
  • 15
    • 0038792224 scopus 로고    scopus 로고
    • Map kinase signaling pathways and hematologic malignancies
    • Platanias LC. Map kinase signaling pathways and hematologic malignancies. Blood. 2003;101 (12): 4667-4679. (Pubitemid 36857719)
    • (2003) Blood , vol.101 , Issue.12 , pp. 4667-4679
    • Platanias, L.C.1
  • 16
    • 48749108800 scopus 로고    scopus 로고
    • Deregulation of signaling pathways in acute myeloid leukemia
    • Scholl C, Gilliland DG, Frohling S. Deregulation of signaling pathways in acute myeloid leukemia. Semin Oncol. 2008;35(4):336-345.
    • (2008) Semin. Oncol. , vol.35 , Issue.4 , pp. 336-345
    • Scholl, C.1    Gilliland, D.G.2    Frohling, S.3
  • 17
    • 33745307617 scopus 로고    scopus 로고
    • Ras, PI(3)K and mTOR signalling controls tumour cell growth
    • DOI 10.1038/nature04869, PII NATURE04869
    • Shaw RJ, Cantley LC. Ras, PI (3) K and mTOR signalling controls tumour cell growth. Nature. 2006;441(7092):424-430. (Pubitemid 44050136)
    • (2006) Nature , vol.441 , Issue.7092 , pp. 424-430
    • Shaw, R.J.1    Cantley, L.C.2
  • 18
    • 3242683662 scopus 로고    scopus 로고
    • Single cell profiling of potentiated phospho-protein networks in cancer cells
    • DOI 10.1016/j.cell.2004.06.028, PII S0092867404006282
    • Irish JM, Hovland R, Krutzik PO, et al. Single cell profiling of potentiated phospho-protein networks in cancer cells. Cell. 2004;118(2):217-228. (Pubitemid 38962577)
    • (2004) Cell , vol.118 , Issue.2 , pp. 217-228
    • Irish, J.M.1    Hovland, R.2    Krutzik, P.O.3    Perez, O.D.4    Bruserud, O.5    Gjertsen, B.T.6    Nolan, G.P.7
  • 19
    • 33746214828 scopus 로고    scopus 로고
    • Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry
    • Irish JM, Czerwinski DK, Nolan GP, Levy R. Kinetics of B cell receptor signaling in human B cell subsets mapped by phosphospecific flow cytometry. J Immunol. 2006;177(3):1581-1589. (Pubitemid 44092493)
    • (2006) Journal of Immunology , vol.177 , Issue.3 , pp. 1581-1589
    • Irish, J.M.1    Czerwinski, D.K.2    Nolan, G.P.3    Levy, R.4
  • 20
    • 33751195937 scopus 로고    scopus 로고
    • Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumorinfiltrating nonmalignant B cells
    • Irish JM, Czerwinski DK, Nolan GP, Levy R. Altered B-cell receptor signaling kinetics distinguish human follicular lymphoma B cells from tumorinfiltrating nonmalignant B cells. Blood. 2006;108(9):3135-3142.
    • (2006) Blood , vol.108 , Issue.9 , pp. 3135-3142
    • Irish, J.M.1    Czerwinski, D.K.2    Nolan, G.P.3    Levy, R.4
  • 21
    • 33747890445 scopus 로고    scopus 로고
    • Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients
    • Chow S, Minden MD, Hedley DW. Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients. Exp Hematol. 2006;34(9):1183-1191.
    • (2006) Exp. Hematol , vol.34 , Issue.9 , pp. 1183-1191
    • Chow, S.1    Minden, M.D.2    Hedley, D.W.3
  • 22
    • 41949127107 scopus 로고    scopus 로고
    • Pharmacodynamic monitoring of moleculartargeted agents in the peripheral blood of leukemia patients using flow cytometry
    • Hedley DW, Chow S, Goolsby C, Shankey TV. Pharmacodynamic monitoring of moleculartargeted agents in the peripheral blood of leukemia patients using flow cytometry. Toxicol Pathol. 2008;36(1):133-139.
    • (2008) Toxicol. Pathol. , vol.36 , Issue.1 , pp. 133-139
    • Hedley, D.W.1    Chow, S.2    Goolsby, C.3    Shankey, T.V.4
  • 23
    • 56849127197 scopus 로고    scopus 로고
    • Flow-cytometric phosphoprotein analysis reveals agonist and temporal differences in responses of murine hematopoietic stem/progenitor cells
    • Kalaitzidis D, Neel BG. Flow-cytometric phosphoprotein analysis reveals agonist and temporal differences in responses of murine hematopoietic stem/progenitor cells. PLoS ONE. 2008;3 (11): e3776.
    • (2008) PLoS ONE , vol.3 , Issue.11
    • Kalaitzidis, D.1    Neel, B.G.2
  • 24
    • 52949129499 scopus 로고    scopus 로고
    • Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates
    • Kotecha N, Flores NJ, Irish JM, et al. Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates. Cancer Cell. 2008;14(4):335-343.
    • (2008) Cancer Cell. , vol.14 , Issue.4 , pp. 335-343
    • Kotecha, N.1    Flores, N.J.2    Irish, J.M.3
  • 25
    • 41149124865 scopus 로고    scopus 로고
    • Single-cell, phosphoepitope-specific analysis demonstrates cell type-and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection
    • DOI 10.1128/JVI.01582-07
    • Lee AW, Sharp ER, O'Mahony A, et al. Singlecell, phosphoepitope-specific analysis demonstrates cell type-and pathway-specific dysregulation of Jak/STAT and MAPK signaling associated with in vivo human immunodeficiency virus type 1 infection. J Virol. 2008;82(7):3702-3712. (Pubitemid 351429946)
    • (2008) Journal of Virology , vol.82 , Issue.7 , pp. 3702-3712
    • Lee, A.W.1    Sharp, E.R.2    O'Mahony, A.3    Rosenberg, M.G.4    Israelski, D.M.5    Nolan, G.P.6    Nixon, D.F.7
  • 26
    • 71049195408 scopus 로고    scopus 로고
    • Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses
    • Han L, Wierenga AT, Rozenveld-Geugien M, van de Lande K, Vellenga E, Schuringa JJ. Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses. PLoS ONE. 2009;4(11):e7989.
    • (2009) PLoS ONE , vol.4 , Issue.11
    • Han, L.1    Wierenga, A.T.2    Rozenveld-Geugien, M.3    Van De Lande, K.4    Vellenga, E.5    Schuringa, J.J.6
  • 27
    • 77955643156 scopus 로고    scopus 로고
    • B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression
    • Irish JM, Myklebust JH, Alizadeh AA, et al. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression. Proc Natl Acad Sci U S A. 2010;107(29):12747-12754.
    • (2010) Proc. Natl. Acad. Sci. U S A , vol.107 , Issue.29 , pp. 12747-12754
    • Irish, J.M.1    Myklebust, J.H.2    Alizadeh, A.A.3
  • 28
    • 79957829905 scopus 로고    scopus 로고
    • Patient-derived acute myeloid leukemia (AML) bone marrow cells display distinct intracellular kinase phosphorylation patterns
    • Shults K, Flye L, Green L, Daly T, Manro JR, Lahn M. Patient-derived acute myeloid leukemia (AML) bone marrow cells display distinct intracellular kinase phosphorylation patterns. Cancer Manage Res. 2009;1:1-11.
    • (2009) Cancer Manage Res. , vol.1 , pp. 1-11
    • Shults, K.1    Flye, L.2    Green, L.3    Daly, T.4    Manro, J.R.5    Lahn, M.6
  • 30
    • 0034657447 scopus 로고    scopus 로고
    • IL-3 signaling and the role of Src kinases, JAKs and STATs: A covert liaison unveiled
    • Reddy EP, Korapati A, Chaturvedi P, Rane S. IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled. Oncogene. 2000;19(21):2532-2547. (Pubitemid 30339209)
    • (2000) Oncogene , vol.19 , Issue.21 , pp. 2532-2547
    • Reddy, E.P.1    Korapati, A.2    Chaturvedi, P.3    Rane, S.4
  • 31
    • 48749117533 scopus 로고    scopus 로고
    • Leukemia stem cells in acute myeloid leukemia
    • Chan WI, Huntly BJ. Leukemia stem cells in acute myeloid leukemia. Semin Oncol. 2008;35(4):326-335.
    • (2008) Semin. Oncol. , vol.35 , Issue.4 , pp. 326-335
    • Chan, W.I.1    Huntly, B.J.2
  • 32
    • 79954596463 scopus 로고    scopus 로고
    • Normal bone marrow signal transduction profiles: A requisite for enhanced detection of signaling dysregulations in AML
    • Marvin J, Swaminathan S, Kraker G, Chadburn A, Jacobberger J, Goolsby C. Normal bone marrow signal transduction profiles: a requisite for enhanced detection of signaling dysregulations in AML. Blood. 2011;117(15):e120-e130.
    • (2011) Blood , vol.117 , Issue.15
    • Marvin, J.1    Swaminathan, S.2    Kraker, G.3    Chadburn, A.4    Jacobberger, J.5    Goolsby, C.6
  • 33
    • 0033619144 scopus 로고    scopus 로고
    • Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts
    • DOI 10.1038/sj.onc.1202939
    • Caruana G, Cambareri AC, Ashman LK. Isoforms of c-KIT differ in activation of signalling pathways and transformation of NIH3T3 fibroblasts. Oncogene. 1999;18(40):5573-5581. (Pubitemid 29481504)
    • (1999) Oncogene , vol.18 , Issue.40 , pp. 5573-5581
    • Caruana, G.1    Cambareri, A.C.2    Ashman, L.K.3
  • 34
    • 44949202353 scopus 로고    scopus 로고
    • Expression of c-Kit isoforms in multiple myeloma: Differences in signaling and drug sensitivity
    • DOI 10.3324/haematol.12171
    • Montero JC, Lopez-Perez R, San Miguel JF, Pandiella A. Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity. Haematologica. 2008;93(6):851-859. (Pubitemid 351821721)
    • (2008) Haematologica , vol.93 , Issue.6 , pp. 851-859
    • Montero, J.C.1    Lopez-Perez, R.2    San Miguel, J.F.3    Pandiella, A.4
  • 35
    • 12144278434 scopus 로고    scopus 로고
    • Normal and oncogenic forms of the receptor tyrosine kinase kit
    • DOI 10.1634/stemcells.2004-0117
    • Lennartsson J, Jelacic T, Linnekin D, Shivakrupa R. Normal and oncogenic forms of the receptor tyrosine kinase kit. Stem Cells. 2005;23(1):16-43. (Pubitemid 40105289)
    • (2005) Stem Cells , vol.23 , Issue.1 , pp. 16-43
    • Lennartsson, J.1    Jelacic, T.2    Linnekin, D.3    Shivakrupa, R.4
  • 36
    • 0842287505 scopus 로고    scopus 로고
    • JAK2 contributes to the intrinsic capacity of primary hematopoietic cells to respond to stem cell factor
    • DOI 10.1016/j.exphem.2003.11.006
    • Radosevic N, Winterstein D, Keller JR, Neubauer H, Pfeffer K, Linnekin D. JAK2 contributes to the intrinsic capacity of primary hematopoietic cells to respond to stem cell factor. Exp Hematol. 2004;32 (2): 149-156. (Pubitemid 38177640)
    • (2004) Experimental Hematology , vol.32 , Issue.2 , pp. 149-156
    • Radosevic, N.1    Winterstein, D.2    Keller, J.R.3    Neubauer, H.4    Pfeffer, K.5    Linnekin, D.6


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