Biological and clinical importance of ovarian cell death

Contemporary Ob-Gyn

Volumn 41, Issue 3, 1996, Pages 59-86

  Tilly, Jonathan L ^a,b   Ratts, Valerie S ^c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0002849968     PISSN: 00903159     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995;267:1456
2. Bylinsky G: Cell suicide. The birth of a mega-market. Fortune 1995;(May 15):75
3. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972;26:239
4. Wyllie AH: Cell death: A new classification separating apoptosis from necrosis, in Bowen ID, Lockshin R (eds): Cell Death In Biology and Pathology. New York, NY, Chapman and Hall, 1981, pp 9-34
5. Vaux DL: Toward an understanding of the molecular mechanisms of physiological cell death. Proc Natl Acad Sci USA 1993;90:786
6. Majno G, Joris I: Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995;146:3
7. Schwartzman RA, Cidlowski JA: Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocrine Rev 1993;14:133
8. Wyllie AH: Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980;284:555
9. Tilly JL, Hsueh AJW: Microscale autoradiographic method for the qualitative and quantitative analysis of apoptotic DNA fragmentation. J Cell Physiol 1993;154:519
10. Gavrieli Y, Sherman Y, Ben-Sasson SA: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493
11. Tilly JL: Use of the terminal transferase DNA labeling reaction for the biochemical and in situ analysis of apoptosis, in Celis JE (ed): Cell Biology. A Laboratory Handbook. Orlando, Fla., Academic Press, 1994, pp 330-337
12. Wyllie AH: The genetic regulation of apoptosis. Curr Opin Genetics Dev 1995;5:97
13. Ellis RE, Yuan J, Horvitz HR: Mechanisms and func tions of cell death. Ann Rev Cell Biol 1991;7:663
14. Flemming W: Uber die bildung von richtungsfiguren in saugethiereiren beim Untergang Graafscher follikel. Arch Anat EntwGesch 1885;221
15. Hirshfield AN: Development of follicles in the mammalian ovary. Int Rev Cytol 1991;124;43
16. Tilly JL: Ovarian follicular atresia: A model to study the mechanisms of physiological cell death. Endocrine J 1993;1:67
17. Baker TG: A quantitative and cytological study of germ cells in human ovaries. Proc Roy Soc Lend (Biol) 1952;158:417
18. Vom Saal FS, Finch CE: Reproductive senescence: Phenomena and mechanisms in mammals and selected vertebrates, in Knobil E, Neill J (eds): The Physiology of Reproduction. New York, NY, Raven Press, 1988, pp 2351-2403
19. Beaumont HM, Mandl AM: A quantitative and cytological study of oogonia and oocytes in the fetal and neonatal rat. Proc Roy Soc Lond (Ser B) 1962;155:557
20. Coucouvanis EC, Sherwood SW, Carswell-Crumpton C, et al: Evidence that the mechanism of prenatal germ cell death in the mouse is apoptosis. Exp Cell Res 1993;209:238
21. Besmer P, Manova K, Duttlinger R, et al: The kit-ligand (Steel factor) and its receptor c-kit/W: Pleiotropic roles in gametogenesis and melanogenesis. Development 1993(Supplement):125
22. Pesce M, Farrace MG, Dolci S, et al: Stem cell factor and leukemia inhibitory factor promote primordial germ cell survival by suppressing programmed cell death (apoptosis). Development 1993;118:1089
23. Korsmeyer SJ: Bcl-2 initiates a new category of oncogenes: Regulators of cell death. Blood 1992;80:879
24. Reed JC: Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994;124:1
25. Ratts VS, Flaws JA, Kolp R, et al: Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the postnatal female mouse gonad. Endocrinology 1995;136:3665
26. Tilly JL, Kowalski KI, Johnson AL, et al: Involvement of apoptosis in ovarian follicular atresia and postovulatory regression. Endocrinology 1991;129:2799
27. Tilly JL, Billig H, Kowalski KI, et al: Epidermal growth factor and basic fibroblast growth factor suppress the spontaneous onset of apoptosis in cultured rat ovarian granulosa cells and follicles by a tyrosine kinase-dependent mechanism. Mol Endocrinol 1992;6:1942
28. Flaws JA, DeSanti A, Tilly KI, et al: Vasoactive intestinal peptide-mediated suppression of apoptosis in the ovary: Potential mechanisms of action and evidence of a conserved anti-atretogenic role through evolution. Endocrinology 1995;136:4351
29. Chun S-Y, Billig H, Tilly JL, et al: Gonadotropin suppression of apoptosis in cultured preovulatory follicles: Mediatory role of endogenous insulin-like growth factor-I. Endocrinology 1994;135:1845
30. Tilly JL, Tilly KI: Inhibitors of oxidative stress mimic the ability of follicle-stimulating hormone to suppress apoptosis in cultured rat ovarian follicles. Endocrinology 1995;136:242
31. Tilly JL, Flaws JA, DeSanti A, et al: Role of intrafollicular growth factors in maturation and atresia of rat ovarian follicles. Biol Reprod 1995;52(Supplement 1):159
32. Billig H, Furuta I, Hsueh AJW: Gonadotropin-releasing hormone directly induces apoptotic death in the rat ovary: Biochemical and in situ detection of DNA fragmentation in granulosa cells. Endocrinology 1994;134:245
33. Kugu K, Tilly JL: Gonadotropin-releasing hormone (GnRH) antagonizes follicle-stimulating hormone (FSH) and transforming growth factor alpha (TGFα)-promoted granulosa cell survival in cultured rat ovarian antral follicles. Proceedings from the 77th Annual Meeting of the Endocrine Society, Washington, DC, 1995;144
34. Tilly JL, Tilly KI, Kenton ML, et al: Expression of members of the bcl-2 gene family in the immature rat ovary: equine chorionic gonadotropin-mediated inhibition of granulosa cell apoptosis is associated with decreased bax and constitutive bcl-2 and bcl-xlong mRNA levels. Endocrinology 1995;136:232
35. Hockenberry DM, Oltvai ZN, Yin X-M, et al: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 1993;75:241
36. Steinman HM: The bcl-2 oncoprotein functions as a pro-oxidant. J Biol Chem 1995;270:3487
37. Buttke TM, Sandstrom PA: Oxidative stress as a mediator of apoptosis. Immunol Today 1994;15:7
38. Miura M, Zhu H, Rotello R, et al: Induction of apoptosis in fibroblasts by IL 1β-converting enzyme, a mammalian homolog of the C elegans death gene ced-3. Cell 1993;75:653
39. Tilly KI, Banerjee S, Banerjee PP, Tilly JL: Expression of the p53 and Wilms' tumor suppressor genes in the rat ovary: Gonadotropin repression in vivo and immunohistochemical localization of nuclear p53 protein to apoptotic granulosa cells of atretic follicles. Endocrinology 1995;136:1394
40. Flaws JA, Kugu K, Trbovich AM, DeSanti A, Tilly KI, Hirshfield AN, Tilly JL: Interleukin-1 β-converting enzyme-related proteases (IRPs) and mammalian cell death: Dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle. Endocrinology 1995;136:in press (November)
41. Richardson SJ, Senikas V, Nelson JF: Follicular depletion during the menopausal transition: Evidence for accelerated loss and ultimate exhaustion. J Clin Endocrinol Metab 1987;65:1231
42. Juengal JL, Garverick HA, Johnson AL, et al: Apoptosis during luteal regression in cattle. Endocrinology 1993;132:249
43. Dharmarajan AM, Goodman SB, Tilly KI, Tilly JL,: Apoptosis during functional corpus luteum regression: Evidence of a role for chorionic gonadotropin in promoting luteal cell survival. Endocrine J 1994;2:295
44. Rueda BR, Tilly KI, Hansen TR, Hoyer PB, Tilly JL: Expression of Superoxide dismutase, catalase and glutathione peroxidase in the bovine corpus luteum: Evidence supporting a role for oxidative stress in luteolysis. Endocrine 1995;3:227
45. Carlson JC, Wu XM, Sawada M: Oxygen radicals and the control of ovarian corpus luteum function. Free Radical Biol Med 1993;14:79
46. Laloraya M, Pradeep KG, Laloraya MM: Changes in the levels of superoxide anion radical and superoxide dismutase during the estrous cycle of Rattus norvegicus and induction of superoxide dismutase in the rat ovary by lutropin. Biochem Biophys Res Commun 1988;157:146
47. Rodgers FE, Fraser HM, Duncan WC, et al: Immunolocalisation of bcl-2 in the human corpus luteum. Human Reprod 1995;10:in press
48. Fraser HM, Lunn SF, Cowen GM, et al: Induced luteal regression in the primate: Evidence for apoptosis and changes in c-myc protein. J Endocrinol 1995;in press
49. Terada N, Yamamoto R, Takada T, et al: Inhibitory effect of progesterone on cell death of mouse uterine epithelium. J Steroid Biochem 1989;33:1091