Asiatic acid induces colon cancer cell growth inhibition and apoptosis through mitochondrial death cascade

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 8, 2009, Pages 1399-1405

  Tang, Xue Lian ^a,b   Yang, Xin Ying ^a   Jung, Hyun Ju ^c   Kim, Sung Yeon ^c   Jung, Suk Yul ^a   Choi, Du Young ^a   Park, Won Cheol ^a   Park, Hyun ^a  

^a Wonkwang University School of Medicine   (South Korea)

^b SOUTH CHINA AGRICULTURAL UNIVERSITY   (China)

^c Wonkwang University   (South Korea)

Author keywords

Apoptosis; Asiatic acid; Colon cancer cell; Mitochondrial death cascade

Indexed keywords

ASIATIC ACID; CASPASE 3; CASPASE 9; CYTOCHROME C; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CELL DEATH; CELL GROWTH; CELL PROLIFERATION; CHEMOPROPHYLAXIS; CHROMATIN CONDENSATION; COLON CANCER; CONTROLLED STUDY; CYTOSOL; DNA FRAGMENTATION; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL PERMEABILITY; MITOCHONDRION; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN SECRETION; TUMOR CELL;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASE 9; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CENTELLA; CHROMATIN; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; CYTOCHROMES C; DNA FRAGMENTATION; FLOW CYTOMETRY; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOCHONDRIA; MOLECULAR STRUCTURE; POLY ADENOSINE DIPHOSPHATE RIBOSE; STOMACH NEOPLASMS; TRITERPENES;

EID: 69149088633     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1399     Document Type: Article

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