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Volumn 48, Issue 5, 2011, Pages 1210-1215

Simulations of trabecular remodeling and fatigue: Is remodeling helpful or harmful?

Author keywords

Fatigue; Microdamage; Osteocytes; Repair; Stress fracture

Indexed keywords

ALGORITHM; ARTICLE; BONE REMODELING; COMPUTER SIMULATION; CONTROLLED STUDY; MECHANICAL STRESS; MECHANICAL TORSION; OSTEOCLAST; OSTEOCYTE; STRESS FRACTURE; TRABECULAR BONE;

EID: 79954578976     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2011.01.011     Document Type: Article
Times cited : (31)

References (46)
  • 1
    • 37849019115 scopus 로고
    • Hypogravitational effects of hypodynamia on bone cell function and the dynamics of bone remodeling
    • NTIS, Springfield, VA, A 14-day ground-based hypokinesia study in nonhuman primates: a compilation of results, 81268.
    • Mathews C.H.E., Aswani S.P., Parfitt A.M. Hypogravitational effects of hypodynamia on bone cell function and the dynamics of bone remodeling. NASA Tech. Mem. 1981, 81268:16-28. NTIS, Springfield, VA.
    • (1981) NASA Tech. Mem. , pp. 16-28
    • Mathews, C.H.E.1    Aswani, S.P.2    Parfitt, A.M.3
  • 2
    • 0024448705 scopus 로고
    • Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation
    • Weinreb M., Rodan G.A., Thompson D.D. Osteopenia in the immobilized rat hind limb is associated with increased bone resorption and decreased bone formation. Bone 1989, 10:187-194.
    • (1989) Bone , vol.10 , pp. 187-194
    • Weinreb, M.1    Rodan, G.A.2    Thompson, D.D.3
  • 3
    • 0022446633 scopus 로고
    • Immobilization-associated osteoporosis in primates
    • Young D.R., Niklowitz W.J., Brown R.J., Jee W.S.S. Immobilization-associated osteoporosis in primates. Bone 1986, 7:109-117.
    • (1986) Bone , vol.7 , pp. 109-117
    • Young, D.R.1    Niklowitz, W.J.2    Brown, R.J.3    Jee, W.S.S.4
  • 4
    • 0021960062 scopus 로고
    • Bone remodeling in response to in vivo fatigue microdamage
    • Burr D.B., Martin R.B., Schaffler M.B., Radin E.L. Bone remodeling in response to in vivo fatigue microdamage. J Biomech 1985, 18:189-200.
    • (1985) J Biomech , vol.18 , pp. 189-200
    • Burr, D.B.1    Martin, R.B.2    Schaffler, M.B.3    Radin, E.L.4
  • 5
    • 0036903495 scopus 로고    scopus 로고
    • Bone adaptation to load: microdamage as a stimulus for bone remodelling
    • Lee T.C., Staines A., Taylor D. Bone adaptation to load: microdamage as a stimulus for bone remodelling. J Anat 2002, 201:437-446.
    • (2002) J Anat , vol.201 , pp. 437-446
    • Lee, T.C.1    Staines, A.2    Taylor, D.3
  • 6
    • 0036139963 scopus 로고    scopus 로고
    • Is all cortical bone remodeling initiated by microdamage?
    • Martin R.B. Is all cortical bone remodeling initiated by microdamage?. Bone 2002, 30:8-13.
    • (2002) Bone , vol.30 , pp. 8-13
    • Martin, R.B.1
  • 7
    • 0027462103 scopus 로고
    • Increased intracortical remodeling following fatigue damage
    • Mori S., Burr D.B. Increased intracortical remodeling following fatigue damage. Bone 1993, 14:103-109.
    • (1993) Bone , vol.14 , pp. 103-109
    • Mori, S.1    Burr, D.B.2
  • 8
    • 0032895922 scopus 로고    scopus 로고
    • Mechanotransduction in bone - role of the lacuno-canalicular network
    • Burger E.H., Klein-Nulend J. Mechanotransduction in bone - role of the lacuno-canalicular network. FASEB J 1999, 13(Suppl):S101-S112.
    • (1999) FASEB J , vol.13 , Issue.SUPPL.
    • Burger, E.H.1    Klein-Nulend, J.2
  • 9
    • 34250008264 scopus 로고    scopus 로고
    • The significance of bone microstructure in mechanotransduction
    • Cowin S.C. The significance of bone microstructure in mechanotransduction. J Biomech 2007, 40(Suppl):S105-S109.
    • (2007) J Biomech , vol.40 , Issue.SUPPL.
    • Cowin, S.C.1
  • 10
    • 0024326174 scopus 로고
    • Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo
    • Skerry T.M., Bitensky L., Chayen J., Lanyon L.E. Early strain-related changes in enzyme activity in osteocytes following bone loading in vivo. J Bone Miner Res 1989, 4:783-788.
    • (1989) J Bone Miner Res , vol.4 , pp. 783-788
    • Skerry, T.M.1    Bitensky, L.2    Chayen, J.3    Lanyon, L.E.4
  • 12
    • 0141565397 scopus 로고    scopus 로고
    • Strain-derived canalicular fluid flow regulates osteoclast activity in a remodeling osteon - a proposal
    • Burger E.H., Klein-Nulend J., Smit T.H. Strain-derived canalicular fluid flow regulates osteoclast activity in a remodeling osteon - a proposal. J Biomech 2003, 36:1453-1459.
    • (2003) J Biomech , vol.36 , pp. 1453-1459
    • Burger, E.H.1    Klein-Nulend, J.2    Smit, T.H.3
  • 13
    • 0036197329 scopus 로고    scopus 로고
    • Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-β: enhancement by estrogen
    • Heino T.J., Hentunen T.A., Väänänen H.K. Osteocytes inhibit osteoclastic bone resorption through transforming growth factor-β: enhancement by estrogen. J Cell Biochem 2002, 85:185-197.
    • (2002) J Cell Biochem , vol.85 , pp. 185-197
    • Heino, T.J.1    Hentunen, T.A.2    Väänänen, H.K.3
  • 15
    • 0033981552 scopus 로고    scopus 로고
    • Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo
    • Verborgt O., Gibson G.J., Schaffler M.B. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo. J Bone Miner Res 2000, 15:60-67.
    • (2000) J Bone Miner Res , vol.15 , pp. 60-67
    • Verborgt, O.1    Gibson, G.J.2    Schaffler, M.B.3
  • 16
    • 0029073707 scopus 로고
    • Mathematical model for repair of fatigue damage and stress fracture in osteonal bone
    • Martin R.B. Mathematical model for repair of fatigue damage and stress fracture in osteonal bone. J Orthop Res 1995, 13:309-316.
    • (1995) J Orthop Res , vol.13 , pp. 309-316
    • Martin, R.B.1
  • 17
    • 49949087400 scopus 로고    scopus 로고
    • Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis
    • Mulvihill B.M., McNamara L.M., Prendergast P.J. Loss of trabeculae by mechano-biological means may explain rapid bone loss in osteoporosis. J R Soc Interface 2008, 5:1243-1253.
    • (2008) J R Soc Interface , vol.5 , pp. 1243-1253
    • Mulvihill, B.M.1    McNamara, L.M.2    Prendergast, P.J.3
  • 18
    • 23644448935 scopus 로고    scopus 로고
    • The epidemiology of thoroughbred racehorse injuries
    • Stover S.M. The epidemiology of thoroughbred racehorse injuries. Clin Tech Equine Pract 2003, 2:312-322.
    • (2003) Clin Tech Equine Pract , vol.2 , pp. 312-322
    • Stover, S.M.1
  • 19
    • 0022181431 scopus 로고
    • Stress fractures in military recruits. A prospective study showing an unusually high incidence
    • Milgrom C., Giladi M., Stein M., Kashtan H., Margulies J.Y., Chisin R., et al. Stress fractures in military recruits. A prospective study showing an unusually high incidence. J Bone Joint Surg Br 1985, 67:732-735.
    • (1985) J Bone Joint Surg Br , vol.67 , pp. 732-735
    • Milgrom, C.1    Giladi, M.2    Stein, M.3    Kashtan, H.4    Margulies, J.Y.5    Chisin, R.6
  • 20
    • 0016677093 scopus 로고
    • Stress fractures in athletes
    • McBryde A.M. Stress fractures in athletes. J Sports Med 1975, 3:212-217.
    • (1975) J Sports Med , vol.3 , pp. 212-217
    • McBryde, A.M.1
  • 22
    • 0013662090 scopus 로고
    • Morphologic analysis of pathology
    • Little, Brown, and Company, Boston, MA, H.M. Frost (Ed.)
    • Johnson L.C. Morphologic analysis of pathology. Bone biodynamics 1964, 543-654. Little, Brown, and Company, Boston, MA. H.M. Frost (Ed.).
    • (1964) Bone biodynamics , pp. 543-654
    • Johnson, L.C.1
  • 23
    • 0034621881 scopus 로고    scopus 로고
    • Effects of mechanical forces on maintenance and adaptation of form in trabecular bone
    • Huiskes R., Ruimerman R., van Lenthe G.H., Janssen J.D. Effects of mechanical forces on maintenance and adaptation of form in trabecular bone. Nature 2000, 405:704-706.
    • (2000) Nature , vol.405 , pp. 704-706
    • Huiskes, R.1    Ruimerman, R.2    van Lenthe, G.H.3    Janssen, J.D.4
  • 24
    • 13844274948 scopus 로고    scopus 로고
    • A theoretical framework for strain-related trabecular bone maintenance and adaptation
    • Ruimerman R., Hilbers P.A.J., van Rietbergen B., Huiskes R. A theoretical framework for strain-related trabecular bone maintenance and adaptation. J Biomech 2005, 38:931-941.
    • (2005) J Biomech , vol.38 , pp. 931-941
    • Ruimerman, R.1    Hilbers, P.A.J.2    van Rietbergen, B.3    Huiskes, R.4
  • 26
    • 0023873049 scopus 로고
    • The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone
    • Currey J.D. The effect of porosity and mineral content on the Young's modulus of elasticity of compact bone. J Biomech 1988, 21:131-191.
    • (1988) J Biomech , vol.21 , pp. 131-191
    • Currey, J.D.1
  • 27
    • 0033811529 scopus 로고    scopus 로고
    • If bone is the answer, then what is the question?
    • Huiskes R. If bone is the answer, then what is the question?. J Anat 2000, 197:145-156.
    • (2000) J Anat , vol.197 , pp. 145-156
    • Huiskes, R.1
  • 28
    • 2042453389 scopus 로고    scopus 로고
    • A computer-simulation model relating bone-cell metabolism to mechanical adaptation of trabecular architecture
    • Ruimerman R., Huiskes R., van Lenthe G.H., Janssen J.D. A computer-simulation model relating bone-cell metabolism to mechanical adaptation of trabecular architecture. Comp Meth Biomech Biomed Eng 2001, 4:433-448.
    • (2001) Comp Meth Biomech Biomed Eng , vol.4 , pp. 433-448
    • Ruimerman, R.1    Huiskes, R.2    van Lenthe, G.H.3    Janssen, J.D.4
  • 29
    • 0029819899 scopus 로고    scopus 로고
    • Diffusion of free nitric oxide
    • Lancaster J. Diffusion of free nitric oxide. Methods Enzymol 1996, 268:31-50.
    • (1996) Methods Enzymol , vol.268 , pp. 31-50
    • Lancaster, J.1
  • 30
    • 0000825469 scopus 로고
    • Simulation of the differential adhesion driven rearrangement of biological cells
    • Glazier J.A., Graner F. Simulation of the differential adhesion driven rearrangement of biological cells. Phys Rev E 1993, 47:2128-2154.
    • (1993) Phys Rev E , vol.47 , pp. 2128-2154
    • Glazier, J.A.1    Graner, F.2
  • 31
    • 0035957392 scopus 로고    scopus 로고
    • How amoeboids self-organize into a fruiting body: multicellular coordination in Dictyostelium discoideum
    • Marée A.F.M., Hogeweg P. How amoeboids self-organize into a fruiting body: multicellular coordination in Dictyostelium discoideum. Proc Natl Acad Sci USA 2001, 98:3879-3883.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3879-3883
    • Marée, A.F.M.1    Hogeweg, P.2
  • 32
    • 0007204555 scopus 로고
    • The cellular basis of bone remodeling
    • Eriksen E.F., Kassem M. The cellular basis of bone remodeling. Triangle 1992, 31:45-57.
    • (1992) Triangle , vol.31 , pp. 45-57
    • Eriksen, E.F.1    Kassem, M.2
  • 33
    • 33947706818 scopus 로고    scopus 로고
    • Bone remodelling algorithms incorporating both strain and microdamage stimuli
    • McNamara L.M., Prendergast P.J. Bone remodelling algorithms incorporating both strain and microdamage stimuli. J Biomech 2007, 40:1381-1391.
    • (2007) J Biomech , vol.40 , pp. 1381-1391
    • McNamara, L.M.1    Prendergast, P.J.2
  • 34
    • 0017278699 scopus 로고
    • Fatigue of compact bone II. Effects of microstructure and density
    • Carter D.R., Hayes W.C., Schurman D.J. Fatigue of compact bone II. Effects of microstructure and density. J Biomech 1976, 9:211-218.
    • (1976) J Biomech , vol.9 , pp. 211-218
    • Carter, D.R.1    Hayes, W.C.2    Schurman, D.J.3
  • 35
    • 5344272497 scopus 로고    scopus 로고
    • Response of the osteocyte syncytium adjacent to and distant from linear microcracks during adaptation to cyclic fatigue loading
    • Colopy S.A., Benz-Dean J., Barrett J.G., Sample S.J., Lu Y., Danova N.A., et al. Response of the osteocyte syncytium adjacent to and distant from linear microcracks during adaptation to cyclic fatigue loading. Bone 2004, 35:881-891.
    • (2004) Bone , vol.35 , pp. 881-891
    • Colopy, S.A.1    Benz-Dean, J.2    Barrett, J.G.3    Sample, S.J.4    Lu, Y.5    Danova, N.A.6
  • 36
    • 33750231849 scopus 로고    scopus 로고
    • The cellular transducer in bone: what is it?
    • Taylor D., Hazenberg J., Lee T.C. The cellular transducer in bone: what is it?. Technol Health Care 2006, 14:367-377.
    • (2006) Technol Health Care , vol.14 , pp. 367-377
    • Taylor, D.1    Hazenberg, J.2    Lee, T.C.3
  • 37
    • 10744221383 scopus 로고    scopus 로고
    • Latham JA Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
    • Winkler D.G., Sutherland M.K., Geoghegan J.C., Yu C., Hayes T., Skonier J.E., et al. Latham JA Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J 2003, 22:6267-6276.
    • (2003) EMBO J , vol.22 , pp. 6267-6276
    • Winkler, D.G.1    Sutherland, M.K.2    Geoghegan, J.C.3    Yu, C.4    Hayes, T.5    Skonier, J.E.6
  • 39
    • 41949089764 scopus 로고    scopus 로고
    • Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
    • Robling A.G., Niziolek P.J., Baldridge L.A., Condon K.W., Allen M.R., Alam I., et al. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem 2008, 283:5866-5875.
    • (2008) J Biol Chem , vol.283 , pp. 5866-5875
    • Robling, A.G.1    Niziolek, P.J.2    Baldridge, L.A.3    Condon, K.W.4    Allen, M.R.5    Alam, I.6
  • 40
    • 0028362416 scopus 로고
    • Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone
    • Parfitt A.M. Osteonal and hemi-osteonal remodeling: the spatial and temporal framework for signal traffic in adult human bone. J Cell Biochem 1994, 55:273-286.
    • (1994) J Cell Biochem , vol.55 , pp. 273-286
    • Parfitt, A.M.1
  • 41
    • 0031723256 scopus 로고    scopus 로고
    • Mechanical loading stimulates bone formation by reactivation of bone lining cells in 13-week-old rats
    • Chow J.W., Wilson A.J., Chambers T.J., Fox S.W. Mechanical loading stimulates bone formation by reactivation of bone lining cells in 13-week-old rats. J Bone Miner Res 1998, 13:1760-1767.
    • (1998) J Bone Miner Res , vol.13 , pp. 1760-1767
    • Chow, J.W.1    Wilson, A.J.2    Chambers, T.J.3    Fox, S.W.4
  • 42
    • 0036135865 scopus 로고    scopus 로고
    • Anisotropic bone remodelling model based on a continuum damage-repair theory
    • Doblare M., Garcia J.M. Anisotropic bone remodelling model based on a continuum damage-repair theory. J Biomech 2002, 35:1-17.
    • (2002) J Biomech , vol.35 , pp. 1-17
    • Doblare, M.1    Garcia, J.M.2
  • 43
    • 0021863318 scopus 로고
    • A continuous damage mechanics model for ductile fracture
    • Lemaitre J. A continuous damage mechanics model for ductile fracture. J Engng Mater Technol 1985, 107:83-89.
    • (1985) J Engng Mater Technol , vol.107 , pp. 83-89
    • Lemaitre, J.1
  • 45
    • 33846591373 scopus 로고    scopus 로고
    • Morphology, localization and accumulation of in vivo microdamage in human cortical bone
    • 998;13:1760-7.
    • Diab T, Vashishth D. Morphology, localization and accumulation of in vivo microdamage in human cortical bone. Bone 2007;40:612-8.998;13:1760-7.
    • (2007) Bone , vol.40 , pp. 612-8
    • Diab, T.1    Vashishth, D.2


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