The potential impact of CD4+ T cell activation and enhanced Th1/Th2 cytokine ratio on HIV-1 secretion in the lungs of individuals with advanced AIDS and active pulmonary infection

Clinical Immunology

Volumn 139, Issue 2, 2011, Pages 142-154

  Rubbo, Pierre Alain ^a   Tuaillon, Edouard ^a   Bolloré, Karine ^a   Foulongne, Vincent ^a   Bourdin, Arnaud ^a   Nagot, Nicolas ^a   Van de Perre, Philippe ^a   Desgranges, Claude ^b   Israël Biet, Dominique ^c   Vendrell, Jean Pierre ^a  

^a MONTPELLIER UNIVERSITY HOSPITAL   (France)

^b INSTITUT COCHIN   (France)

^c HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

CD4+ T cell activation; Compartmentalization; Effector memory cells; HIV 1; Lung; Th1 cytokines

Indexed keywords

CYTOKINE; GAMMA INTERFERON; VIRUS DNA; VIRUS RNA;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DISEASE COURSE; ENZYME LINKED IMMUNOSPOT ASSAY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; LUNG INFECTION; LUNG LAVAGE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS DETECTION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTIGENS, CD; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CYCLOHEXIMIDE; CYTOKINES; DNA, VIRAL; HIV ANTIGENS; HIV-1; HUMANS; IMMUNOPHENOTYPING; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; LUNG; LYMPHOCYTE ACTIVATION; RECEPTORS, CCR5; RECEPTORS, CXCR4; RESPIRATORY TRACT INFECTIONS; RNA, VIRAL; T-LYMPHOCYTE SUBSETS; VIRAL LOAD; VIRAL TROPISM; VIRUS REPLICATION;

EID: 79954568546     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2011.01.007     Document Type: Article

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