GSK-3β negatively regulates megakaryocyte differentiation and platelet production from primary human bone marrow cells in vitro

Platelets

Volumn 22, Issue 3, 2011, Pages 196-203

  Ono, Mayumi ^a,b   Matsubara, Yumiko ^a   Shibano, Toshiro ^a,b   Ikeda, Yasuo ^a,c   Murata, Mitsuru ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b DAIICHI SANKYO CO   (Japan)

^c WASEDA UNIVERSITY   (Japan)

Author keywords

glycogen synthase kinase 3; Megakaryocytes; platelets; thrombopoietin

Indexed keywords

FIBRINOGEN RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; GLYCOPROTEIN IB ALPHA; KERATIN; PROPIDIUM IODIDE; THROMBOPOIETIN; TRANSFORMING GROWTH FACTOR BETA; WNT PROTEIN;

APOPTOSIS; ARTICLE; BLOOD CLOTTING; CELL CYCLE; CELL DIFFERENTIATION; CELL DIVISION; CELL MATURATION; CELL METABOLISM; CELL POPULATION; ENZYME INHIBITION; FLOW CYTOMETRY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIPID TRANSPORT; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; THROMBOCYTOPOIESIS;

BLOOD PLATELETS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELLS, CULTURED; DOWN-REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; IMMUNOHISTOCHEMISTRY; MAP KINASE SIGNALING SYSTEM; MEGAKARYOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PYRIMIDINES; PYRROLES; THROMBOPOIETIN;

ERINACEIDAE;

EID: 79954567767     PISSN: 09537104     EISSN: 13691635     Source Type: Journal    
DOI: 10.3109/09537104.2010.541959     Document Type: Article

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