Particulate matter-induced lung inflammation increases systemic levels of PAI-1 and activates coagulation through distinct mechanisms

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Budinger, G R Scott ^a   McKell, Joanne L ^a   Urich, Daniela ^a   Foiles, Nancy ^a   Weiss, Ivy ^a   Chiarella, Sergio E ^a   Gonzalez, Angel ^a   Soberanes, Saul ^a   Ghio, Andrew J ^b   Nigdelioglu, Recep ^a   Mutlu, Ece A ^c   Radigan, Kathryn A ^a   Green, David ^a   Kwaan, Hau C ^a   Mutlu, Gökhan M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^c RUSH MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRIN; INTERLEUKIN 6; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBIN ANTITHROMBIN COMPLEX; THROMBOPLASTIN; TUMOR NECROSIS FACTOR ALPHA;

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLEEDING TIME; BLOOD CLOTTING; CONTROLLED STUDY; FIBRIN DEPOSITION; LUNG; MALE; MOUSE; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PARTICULATE MATTER; PNEUMONIA; THROMBOGENESIS; THROMBOPLASTIN TIME; URBAN AREA; ANIMAL; BLOOD; CITY; EXPOSURE; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; PARTICLE SIZE; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; WHITE ADIPOSE TISSUE;

MUS;

ADIPOSE TISSUE, WHITE; ANIMALS; BLOOD COAGULATION; CELL LINE, TUMOR; CITIES; FIBRIN; HUMANS; INHALATION EXPOSURE; INTERLEUKIN-6; LUNG; MICE; PARTICLE SIZE; PARTICULATE MATTER; PLASMINOGEN ACTIVATOR INHIBITOR 1; PNEUMONIA; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79954551851     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018525     Document Type: Article

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