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Volumn 300, Issue 3, 2011, Pages

Cyclophosphamide induces NR2B phosphorylation-dependent facilitation on spinal reflex potentiation

Author keywords

Cyclin dependent protein kinase 5; N methyl d aspartate receptor NR2B subunit; Nitric oxide; Pelvic nerve; Urethra; Visceral pain

Indexed keywords

BETA ACTIN; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLOHEXIMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; ROSCOVITINE; SMALL INTERFERING RNA;

EID: 79954547984     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00531.2010     Document Type: Article
Times cited : (7)

References (43)
  • 2
    • 0035369919 scopus 로고    scopus 로고
    • NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity
    • Ali DW, Salter MW. NMDA receptor regulation by Src kinase signalling in excitatory synaptic transmission and plasticity. Curr Opin Neurobiol 11: 336-342, 2001.
    • (2001) Curr Opin Neurobiol , vol.11 , pp. 336-342
    • Ali, D.W.1    Salter, M.W.2
  • 4
    • 0026684242 scopus 로고
    • The effect of glutamate antago-nists on c-fos expression induced in spinal neurons by irritation of the lower urinary tract
    • Birder LA, De Groat WC. The effect of glutamate antago-nists on c-fos expression induced in spinal neurons by irritation of the lower urinary tract. Brain Res 580: 115-120, 1992.
    • (1992) Brain Res , vol.580 , pp. 115-120
    • Birder, L.A.1    de Groat, W.C.2
  • 9
    • 70349235380 scopus 로고    scopus 로고
    • Inhibition of CDKS by roscovitine suppressed LPS-induced NO production through inhibiting of NFkB activation and BH4 biosynthesis in macrophage
    • Du Jianhai Wei N, Guan T, Xu H, An J, Pritchard KA, Shi Y. Inhibition of CDKS by roscovitine suppressed LPS-induced NO production through inhibiting of NFkB activation and BH4 biosynthesis in macrophage. Am J Physiol Cell Physiol 297: C742-C749, 2009.
    • (2009) Am J Physiol Cell Physiol , vol.297
    • du Jianhai Wei, N.1    Guan, T.2    Xu, H.3    An, J.4    Pritchard, K.A.5    Shi, Y.6
  • 11
    • 0025371109 scopus 로고
    • Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat
    • Häbler HJ, Jänig W, Koltzenburg M. Activation of unmyelinated afferent fibres by mechanical stimuli and inflammation of the urinary bladder in the cat. J Physiol (Lond) 425: 545-562, 1990.
    • (1990) J Physiol (Lond) , vol.425 , pp. 545-562
    • Häbler, H.J.1    Jänig, W.2    Koltzenburg, M.3
  • 12
    • 0002669485 scopus 로고    scopus 로고
    • Epidemiology of interstitial cystitis
    • edited by Sant GR. Philadelphia, PA: 1997
    • Ho N, Koziol JA, Parsons CL. Epidemiology of interstitial cystitis. In: Interstitial Cystitis, edited by Sant GR. Philadelphia, PA: 1997, p. 9-16.
    • Interstitial Cystitis , pp. 9-16
    • Ho, N.1    Koziol, J.A.2    Parsons, C.L.3
  • 13
    • 0028334365 scopus 로고
    • NMDA and quisqualate modulation of visceral nociception in the rat
    • Kolhekar R, Gebhart GF. NMDA and quisqualate modulation of visceral nociception in the rat. Brain Res 651: 215-226, 1994.
    • (1994) Brain Res , vol.651 , pp. 215-226
    • Kolhekar, R.1    Gebhart, G.F.2
  • 14
    • 34250335972 scopus 로고    scopus 로고
    • Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation
    • Korkmaz A, Topal T, Oter S. Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell BiolToxicol 23: 303-312, 2007.
    • (2007) Cell BiolToxicol , vol.23 , pp. 303-312
    • Korkmaz, A.1    Topal, T.2    Oter, S.3
  • 15
    • 0037292991 scopus 로고    scopus 로고
    • Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats
    • Lin TB. Dynamic pelvic-pudendal reflex plasticity mediated by glutamate in anesthetized rats. Neuropharmacology 44: 163-170, 2003.
    • (2003) Neuropharmacology , vol.44 , pp. 163-170
    • Lin, T.B.1
  • 16
    • 0028334365 scopus 로고
    • NMDA and quisqualate modulation of visceral nociception in the rat
    • Lippincott-Raven Kolhekar R, Gebhart GF. NMDA and quisqualate modulation of visceral nociception in the rat. Brain Res 651: 215-226, 1994.
    • (1994) Brain Res , vol.651 , pp. 215-226
    • Lippincott-Raven Kolhekar, R.1    Gebhart, G.F.2
  • 19
    • 0036394434 scopus 로고    scopus 로고
    • Involvement of N-methyl-D-aspartate receptors in nociception in the cyclophosphamide-induced visceral pain model in the conscious rat
    • Meen M, Coudore-Civiale MA, Parry L, Eschalier A, Boucher M. Involvement of N-methyl-D-aspartate receptors in nociception in the cyclophosphamide-induced visceral pain model in the conscious rat. Eur J Pain 6: 307-314, 2002.
    • (2002) Eur J Pain , vol.6 , pp. 307-314
    • Meen, M.1    Coudore-Civiale, M.A.2    Parry, L.3    Eschalier, A.4    Boucher, M.5
  • 20
    • 0000927212 scopus 로고
    • The major tyrosine-phosphory-lated protein in the post-synaptic density fraction is N-methyl-D-aspartate receptor subunit 2B
    • Moon IS, Apperson ML, Kenedy MB. The major tyrosine-phosphory-lated protein in the post-synaptic density fraction is N-methyl-D-aspartate receptor subunit 2B. Proc Natl Acad Sci USA 91: 3954-3958, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3954-3958
    • Moon, I.S.1    Apperson, M.L.2    Kenedy, M.B.3
  • 21
    • 8644280515 scopus 로고    scopus 로고
    • Cyclophosphamide-induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder
    • Murray E, Malley SE, Qiao LY, Hu VY, Vizzard MA. Cyclophosphamide-induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder. J Urol 172: 2434-2439, 2004.
    • (2004) J Urol , vol.172 , pp. 2434-2439
    • Murray, E.1    Malley, S.E.2    Qiao, L.Y.3    Hu, V.Y.4    Vizzard, M.A.5
  • 22
    • 78650702451 scopus 로고    scopus 로고
    • Protein Kinase A-dependent spinal a-amino-3-hydroxy-5-methyl-4-isoxa-zole proprionate receptor mediates capsaicin-induced colon-urethra cross-organ reflex sensitization
    • Peng HY, Chang CH, Tsai SJ, Lai CY, Tung KC, Wu HC, Lin TB. Protein Kinase A-dependent spinal a-amino-3-hydroxy-5-methyl-4-isoxa-zole proprionate receptor mediates capsaicin-induced colon-urethra cross-organ reflex sensitization. Anesthesiology 114: 70-83, 2011.
    • (2011) Anesthesiology , vol.114 , pp. 70-83
    • Peng, H.Y.1    Chang, C.H.2    Tsai, S.J.3    Lai, C.Y.4    Tung, K.C.5    Wu, H.C.6    Lin, T.B.7
  • 25
    • 77749271107 scopus 로고    scopus 로고
    • PI3K modulates estrogen-dependent facilitation of colon-to-urethra cross-organ reflex sensitization in ovariectomized female rats
    • Peng HY, Chen GD, Lai CY, Hsieh MC, Hsu HH, Wu HC, Lin TB. PI3K modulates estrogen-dependent facilitation of colon-to-urethra cross-organ reflex sensitization in ovariectomized female rats. J Neurochem 113: 54-66, 2010.
    • (2010) J Neurochem , vol.113 , pp. 54-66
    • Peng, H.Y.1    Chen, G.D.2    Lai, C.Y.3    Hsieh, M.C.4    Hsu, H.H.5    Wu, H.C.6    Lin, T.B.7
  • 26
    • 74049103334 scopus 로고    scopus 로고
    • Endogenous ephrinB2 mediates colon-urethra cross-organ sensitization via Src kinase-dependent tyrosine phosphorylation of NR2B
    • Peng HY, Chen GD, Lai CH, Tung KC, Chang JL, Lin TB. Endogenous ephrinB2 mediates colon-urethra cross-organ sensitization via Src kinase-dependent tyrosine phosphorylation of NR2B. Am J Physiol Renal Physiol 298: F109-F117, 2010.
    • (2010) Am J Physiol Renal Physiol , vol.298
    • Peng, H.Y.1    Chen, G.D.2    Lai, C.H.3    Tung, K.C.4    Chang, J.L.5    Lin, T.B.6
  • 32
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
    • Petralia RS, Wang YX, Wenthold RJ. The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J Neurosci 14: 6102-6120, 1994.
    • (1994) J Neurosci , vol.14 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.X.2    Wenthold, R.J.3
  • 33
    • 33847716296 scopus 로고    scopus 로고
    • Region-specific changes in the phosphorylation of ERK 1/2 and ERK 5 in rat micturition pathways following cyclophosph-amide-induced cystitis
    • Qiao LY, Gulick MA. Region-specific changes in the phosphorylation of ERK 1/2 and ERK 5 in rat micturition pathways following cyclophosph-amide-induced cystitis. Am J Physiol Regul Integr Comp Physiol 292: R1375-R1386, 2007.
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292
    • Qiao, L.Y.1    Gulick, M.A.2
  • 34
    • 0037152582 scopus 로고    scopus 로고
    • Cystitis-induced upregulation of tyrosine kinase (TrkA, TrkB) receptor expression and phosphorylation in rat micturition pathways
    • Qiao LY, Vizzard MA. Cystitis-induced upregulation of tyrosine kinase (TrkA, TrkB) receptor expression and phosphorylation in rat micturition pathways. J Comp Neurol 454: 200-211, 2002.
    • (2002) J Comp Neurol , vol.454 , pp. 200-211
    • Qiao, L.Y.1    Vizzard, M.A.2    Vizzard, M.A.3
  • 35
    • 0345827905 scopus 로고    scopus 로고
    • Up-regulation of phosphorylated CREB but not c-Jun in bladder afferent neurons in dorsal root ganglia after cystitis
    • Qiao LY, Vizzard MA. Up-regulation of phosphorylated CREB but not c-Jun in bladder afferent neurons in dorsal root ganglia after cystitis. J Comp Neurol 469: 262-274, 2004.
    • (2004) J Comp Neurol , vol.469 , pp. 262-274
    • Qiao, L.Y.1    Vizzard, M.A.2
  • 36
    • 73849119395 scopus 로고    scopus 로고
    • R-roscovi-tine (Seliciclib) Affects CLL Cells More strongly than combination of fludarabine or cladribine with cyclophosphaminde: Inhibition of CDK7 sensitizes leukemic cell to caspase-dependent apoptosis
    • Rogalinska M, Blonski JZ, Komina O, Goralski P, Zolnierczyk JD, Piekarski H, Robak T, Kilianska ZM, Wesierska-Gadek J. R-roscovi-tine (Seliciclib) Affects CLL Cells More strongly than combination of fludarabine or cladribine with cyclophosphaminde: inhibition of CDK7 sensitizes leukemic cell to caspase-dependent apoptosis. J Cell Biochem 109: 217-235, 2010.
    • (2010) J Cell Biochem , vol.109 , pp. 217-235
    • Rogalinska, M.1    Blonski, J.Z.2    Komina, O.3    Goralski, P.4    Zolnierczyk, J.D.5    Piekarski, H.6    Robak, T.7    Kilianska, Z.M.8    Wesierska-Gadek, J.9
  • 37
    • 0027997813 scopus 로고
    • Mechanosensitive properties of pelvic nerve afferent fibres innervating the urinary bladder of the rat
    • Sengupta JN, Gebhart GF. Mechanosensitive properties of pelvic nerve afferent fibres innervating the urinary bladder of the rat. J Neurophysiol 72: 2420-2430, 1994.
    • (1994) J Neurophysiol , vol.72 , pp. 2420-2430
    • Sengupta, J.N.1    Gebhart, G.F.2
  • 38
    • 0023840207 scopus 로고
    • Cyclophosphamide-induced cystitis. A review of 100 patients
    • Stillwell TJ, Benson RC. Cyclophosphamide-induced cystitis. A review of 100 patients. Cancer 61: 451-457, 1988.
    • (1988) Cancer , vol.61 , pp. 451-457
    • Stillwell, T.J.1    Benson, R.C.2
  • 39
    • 0035968929 scopus 로고    scopus 로고
    • Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats
    • Tao F, Tao YX, Gonzalez JA, Fang M, Mao P, Johns RA. Knockdown of PSD-95/SAP90 delays the development of neuropathic pain in rats. Neuroreport 12: 3251-3255, 2001.
    • (2001) Neuroreport , vol.12 , pp. 3251-3255
    • Tao, F.1    Tao, Y.X.2    Gonzalez, J.A.3    Fang, M.4    Mao, P.5    Johns, R.A.6
  • 40
    • 0029933629 scopus 로고    scopus 로고
    • Increased expression of neuronal nitric oxide synthesis in bladder afferent pathway following chronic bladder irritation
    • Vizzard MA, Erdman SL, de Groat WC. Increased expression of neuronal nitric oxide synthesis in bladder afferent pathway following chronic bladder irritation. J Comp Neurol 370: 191-202, 1996.
    • (1996) J Comp Neurol , vol.370 , pp. 191-202
    • Vizzard, M.A.1    Erdman, S.L.2    de Groat, W.C.3
  • 42
    • 0033152346 scopus 로고    scopus 로고
    • Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation
    • Yoshimura N, de Groat WC. Increased excitability of afferent neurons innervating rat urinary bladder after chronic bladder inflammation. J Neurosci 19: 4644-4653, 1999.
    • (1999) J Neurosci , vol.19 , pp. 4644-4653
    • Yoshimura, N.1    de Groat, W.C.2
  • 43
    • 0032833183 scopus 로고    scopus 로고
    • The NMDA receptor antagonist dizocilpine attenuates c-Fos expression in the lumbo- sacral spinal cord following repetitive noxious and non-noxious colorectal distention
    • Zhai QZ, Traub RJ. The NMDA receptor antagonist dizocilpine attenuates c-Fos expression in the lumbo- sacral spinal cord following repetitive noxious and non-noxious colorectal distention. Pain 83: 321-329, 1999.
    • (1999) Pain , vol.83 , pp. 321-329
    • Zhai, Q.Z.1    Traub, R.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.