(R)-roscovitine prolongs the mean open time of unitary N-type calcium channel currents

Neuroscience

Volumn 167, Issue 3, 2010, Pages 838-849

  DeStefino, N R ^a   Pilato, A A ^a   Dittrich, M ^b   Cherry, S V ^a   Cho, S ^a   Stiles, J R ^a,b,c   Meriney, S D ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b PITTSBURGH SUPERCOMPUTING CENTER   (United States)

^c CARNEGIE MELLON UNIVERSITY   (United States)

Author keywords

Channel kinetics; Conductance; Patch clamp; Roscovitine; Single channel current; Voltage gated calcium channel

Indexed keywords

CALCIUM CHANNEL N TYPE; ROSCOVITINE;

ARTICLE; CELL SURFACE; CHANNEL GATING; CONDUCTANCE; CONTROLLED STUDY; DYNAMICS; HUMAN; HUMAN CELL; KINETICS; MONTE CARLO METHOD; NEUROTRANSMISSION; PATCH CLAMP; PRIORITY JOURNAL;

ANIMALS; CALCIUM CHANNELS, N-TYPE; CALCIUM SIGNALING; CELL LINE; CELL MEMBRANE; COMPUTER SIMULATION; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MONTE CARLO METHOD; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE INHIBITORS; PURINES; RATS; SYNAPTIC TRANSMISSION; TIME FACTORS;

EID: 77951296911     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.02.041     Document Type: Article

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