Heme sensitization to TNF-Mediated programmed cell death

Advances in Experimental Medicine and Biology

Volumn 691, Issue , 2011, Pages 211-219

  Gozzelino, Raffaella ^a   Soares, Miguel P ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

HEME; HEMOPROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHEMOGLOBIN; PROTEIN C JUN; TUMOR NECROSIS FACTOR;

APOPTOSIS; CELL TYPE; CONFERENCE PAPER; CYTOTOXICITY; DISEASE SEVERITY; HEME SYNTHESIS; HUMAN; IMMUNE MEDIATED INJURY; MALARIA; MOUSE; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; PLASMODIUM MALARIAE; PLASMODIUM MALARIAE INFECTION; PRIORITY JOURNAL; SPOROZOITE; ANIMAL; ARTICLE; BIOLOGICAL MODEL; METABOLISM; PATHOLOGY;

ANIMALS; APOPTOSIS; HEME; HUMANS; MALARIA; MICE; MODELS, IMMUNOLOGICAL; TUMOR NECROSIS FACTORS;

EID: 79954435482     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4419-6612-4_22     Document Type: Conference Paper

References (45)

1. Gozzelino R, Jeney V, Soares M (2010) Mechanisms of cell protection by heme oxygnease-1. Ann Rev Pharmacol Toxicol 50:323-354
2. Furuyama K, Kaneko K, Vargas PD (2007) Heme as a magnificent molecule with multiple missions: Heme determines its own fate and governs cellular homeostasis. Tohoku J Exp Med 213:1-16
3. Tsiftsoglou AS, Tsamadou AI, Papadopoulou LC (2006) Heme as key regulator of major mammalian cellular functions: Molecular, cellular, and pharmacological aspects. Pharmacol Ther 111:327-345
4. Mustafa AK, Gadalla MM, Snyder SH (2009) Signaling by gasotransmitters. Sci Signal 2:re2
5. Fenton HJH (1894) Oxidation of tartaric acid in presence of iron. Journal of the Chemical society (Lond.) 65
6. Balla G, Jacob HS, Balla J, Rosenberg M, Nath K, Apple F, Eaton JW, Vercellotti GM (1992) Ferritin: A cytoprotective antioxidant strategem of endothelium. Journal of Biological Chemistry 267:18148-18153
7. Jeney V, Balla J, Yachie A, Varga Z, Vercellotti GM, Eaton JW, Balla G (2002) Pro-oxidant and cytotoxic effects of circulating heme. Blood 100:879-887
8. Soares MP, Bach FH (2009) Heme oxygenase-1: From biology to therapeutic potential. Trends Mol Med 15:50-58
9. Ferreira A, Balla J, Jeney V, Balla G, Soares MP (2008) A central role for free heme in the pathogenesis of severe malaria: The missing link? J Mol Med 86:1097-1111
10. Seixas E, Gozzelino R, Chora A, Ferreira A, Silva G, Larsen R, Rebelo S, Penido C, Smith NR, Coutinho A, Soares MP (2009) Heme oxygenase-1 affords protection against noncerebral forms of severe malaria. Proc Natl Acad Sci U S A 106:15837-15842
11. Snow RW, Guerra CA, Noor AM, Myint HY, Hay SI. 2005. The global distribution of clinical episodes of Plasmodium falciparum malaria. Nature 434:214-217
12. Miller LH, Baruch DI, Marsh K, Doumbo OK (2002) The pathogenic basis of malaria. Nature 415:673-679
13. Mota MM, Pradel G, Vanderberg JP, Hafalla JC, Frevert U, Nussenzweig RS, Nussenzweig V, Rodriguez A (2001) Migration of Plasmodium sporozoites through cells before infection. Science 291:141-144
14. Prudencio M, Rodriguez A, Mota MM (2006) The silent path to thousands of merozoites: The Plasmodium liver stage. Nat Rev Microbiol 4:849-856
15. Bach FH, Hancock WW, Ferran C (1997) Protective genes expressed in endothelial cells - a regulatory response to injury. Immunology Today 18:483-486
16. Epiphanio S, Albuquerque S, Soares S, MotaMM(2005) The role of HO-1 and CO inMalaria Hepatic Stage. In ELSO Meeting. Dresden, Germany
17. WHO (2000) Expert Committee on Malaria: 20th Report. http://www.rbm.who. int/docs/ ecr20.pdf
18. Idro R, Jenkins NE, Newton CR (2005) Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol 4:827-840
19. Marsh K, Forster D, Waruiru C, Mwangi I, Winstanley M, Marsh V, Newton C, Winstanley P, Warn P, Peshu N et al (1995) Indicators of life-threatening malaria in African children. N Engl J Med 332:1399-1404
20. Maitland K, Marsh K (2004) Pathophysiology of severe malaria in children. Acta Trop 90:131-140
21. Francis SE, Sullivan DJ Jr, Goldberg DE (1997) Hemoglobin metabolism in the malaria parasite Plasmodium falciparum. Annu Rev Microbiol 51:97-123
22. Kristiansen M, Graversen JH, Jacobsen C, Sonne O, Hoffman HJ, Law SK, Moestrup SK (2001) Identification of the haemoglobin scavenger receptor. Nature. 409:198-201
23. Pamplona A, Ferreira A, Balla J, Jeney V, Balla G, Epiphanio S, Chora A, Rodrigues CD, Gregoire IP, Cunha-RodriguesM, Portugal S, SoaresMP, MotaMM(2007) Heme oxygenase- 1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria. Nat Med 13:703-710
24. Rother RP, Bell L, Hillmen P, Gladwin MT. 2005. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: A novel mechanism of human disease. Jama 293:1653-1662
25. Uko EK, Udoh AE, Etukudoh MH (2003) Methaemoglobin profile in malaria infected children in Calabar. Niger J Med 12:94-97
26. Bunn HF, Jandl JH (1966) Exchange of heme among hemoglobin molecules. Proc Natl Acad Sci U S A 56:974-978
27. Paoli M, Anderson BF, Baker HM, Morgan WT, Smith A, Baker EN (1999) Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two beta-propeller domains. Nat Struct Biol 6:926-931
28. Fasano M, Fanali G, Leboffe L, Ascenzi P (2007) Heme binding to albuminoid proteins is the result of recent evolution. IUBMB Life 59:436-440
29. Allhorn M, Berggard T, Nordberg J, Olsson ML, Akerstrom B (2002) Processing of the lipocalin alpha(1)-microglobulin by hemoglobin induces heme-binding and heme-degradation properties. Blood 99:1894-901
30. Miller YI, Shaklai N (1999) Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation. Biochim Biophys Acta 1454:153-164
31. Tolosano E, Fagoonee S, Morello N, Vinchi F, Fiorito V (2009) Heme Scavenging and the other facets of Hemopexin. Antioxid Redox Signal
32. Krishnamurthy P, Xie T, Schuetz JD (2007) The role of transporters in cellular heme and porphyrin homeostasis. Pharmacol Ther 114:345-358
33. Latunde-Dada GO, Simpson RJ, McKie AT (2006) Recent advances in mammalian haem transport. Trends Biochem Sci 31:182-188
34. Grau GE, Fajardo LF, Piguet PF, Allet B, Lambert PH, Vassalli P (1987) Tumor necrosis factor (cachectin) as an essential mediator in murine cerebral malaria. Science 237:1210-1212
35. McGuire W, Hill AV, Allsopp CE, Greenwood BM, Kwiatkowski D (1994) Variation in the TNF-alpha promoter region associated with susceptibility to cerebral malaria. Nature 371:508-510
36. Sinha S, Mishra SK, Sharma S, Patibandla PK, Mallick PK, Sharma SK, Mohanty S, Pati SS, Ramteke BK, Bhatt R, Joshi H, Dash AP, Ahuja RC, Awasthi S, Venkatesh V, Habib S (2008) Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar J 7:13
37. Medzhitov R (2009) Damage control in host-pathogen interactions. Proc Natl Acad Sci U S A 106 15525-15526
38. Aggarwal BB (2003) Signalling pathways of the TNF superfamily: A double-edged sword. Nat Rev Immunol 3:745-756
39. Clark IA (2007) How TNF was recognized as a key mechanism of disease. Cytokine Growth Factor Rev 18:335-343
40. Tartaglia LA, RotheM, Hu YF, Goeddel DV (1993) Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor. Cell 73:213-216
41. Wallach D, Varfolomeev EE, Malinin NL, Goltsev YV, Kovalenko AV, Boldin MP (1999) Tumor necrosis factor receptor and Fas signaling mechanisms. Annu Rev Immunol 17: 331-367
42. Beg AA, Baltimore D (1996) An essential role for NF-kB in preventing TNF-a-induced cell death. Science 274:782-784
43. ChurchillME, SuzukiM(1989) 'SPKK' motifs prefer to bind to DNA at A/T-rich sites. Embo J 8:4189-4195
44. Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA et al (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43
45. Kumar S, Bandyopadhyay U (2005) Free heme toxicity and its detoxification systems in human. Toxicol Lett 157:175-188