메뉴 건너뛰기




Volumn 90, Issue 2, 2004, Pages 131-140

Pathophysiology of severe malaria in children

Author keywords

Acidosis; African children; Falciparum; Malaria; Pathogenesis

Indexed keywords

ALBUMIN; ANTICONVULSIVE AGENT; BICARBONATE; CYTOKINE; INFUSION FLUID; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; MANNITOL; NITRIC OXIDE; OXYGEN; OXYGEN RADICAL; QUININE; TUMOR NECROSIS FACTOR;

EID: 1442335013     PISSN: 0001706X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actatropica.2003.11.010     Document Type: Review
Times cited : (86)

References (83)
  • 2
    • 0036697783 scopus 로고    scopus 로고
    • Breaking down the blood-brain barrier: Signaling a path to cerebral malaria?
    • Adams S., Brown H., Turner G. Breaking down the blood-brain barrier: signaling a path to cerebral malaria? Trends Parasitol. 18:2002;360-366.
    • (2002) Trends Parasitol. , vol.18 , pp. 360-366
    • Adams, S.1    Brown, H.2    Turner, G.3
  • 3
    • 0032495576 scopus 로고    scopus 로고
    • Management of life-threatening acid-base disorders. Second of two parts
    • Adrogue H.J., Madias N.E. Management of life-threatening acid-base disorders. Second of two parts. N. Engl. J. Med. 338:1998;107-111.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 107-111
    • Adrogue, H.J.1    Madias, N.E.2
  • 7
    • 1442354385 scopus 로고    scopus 로고
    • American Heart Association.
    • Pediatric Advanced Life Support 1997-1999, 1997. Emergency Cardiovascular Care Programs, American Heart Association.
    • (1997) Emergency Cardiovascular Care Programs
  • 8
    • 0036176967 scopus 로고    scopus 로고
    • Pathogenesis of Plasmodium falciparum malaria: The roles of parasite adhesion and antigenic variation
    • Beeson J.G., Brown G.V. Pathogenesis of Plasmodium falciparum malaria: the roles of parasite adhesion and antigenic variation. Cell Mol. Life Sci. 59:2002;258-271.
    • (2002) Cell Mol. Life Sci. , vol.59 , pp. 258-271
    • Beeson, J.G.1    Brown, G.V.2
  • 10
    • 0026575099 scopus 로고
    • The incidence and outcome of neurological abnormalities in childhood cerebral malaria: A long-term follow-up of 62 survivors
    • Bondi F.S. The incidence and outcome of neurological abnormalities in childhood cerebral malaria: a long-term follow-up of 62 survivors. Trans. R. Soc. Trop. Med. Hyg. 86:1992;17-19.
    • (1992) Trans. R. Soc. Trop. Med. Hyg. , vol.86 , pp. 17-19
    • Bondi, F.S.1
  • 11
    • 0030011909 scopus 로고    scopus 로고
    • Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: What we do and do not know about cytokine regulation
    • Bone R.C. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation. Crit. Care Med. 24:1996;163-172.
    • (1996) Crit. Care Med. , vol.24 , pp. 163-172
    • Bone, R.C.1
  • 14
    • 1442329868 scopus 로고
    • Malaria in African infants and children in Southern Nigeria
    • Bruce-Chwatt L.J. Malaria in African infants and children in Southern Nigeria. Ann. Trop. Med. Parasitol. 79:1952;549-562.
    • (1952) Ann. Trop. Med. Parasitol. , vol.79 , pp. 549-562
    • Bruce-Chwatt, L.J.1
  • 15
    • 0025776193 scopus 로고
    • Role of early fluid resuscitation in pediatric septic shock
    • Carcillo J.A., Davis A.L., Zaritsky A. Role of early fluid resuscitation in pediatric septic shock. JAMA. 266:1991;1242-1245.
    • (1991) JAMA , vol.266 , pp. 1242-1245
    • Carcillo, J.A.1    Davis, A.L.2    Zaritsky, A.3
  • 16
    • 0026463446 scopus 로고
    • Child morbidity and mortality due to cerebral malaria in Brazzaville, Congo. a retrospective and prospective hospital-based study 1983-1989
    • Carme B., Yombi B., Bouquety J.C., Plassard H., Nzingoula S., Senga J., Akani I. Child morbidity and mortality due to cerebral malaria in Brazzaville, Congo. A retrospective and prospective hospital-based study 1983-1989. Trop. Med. Parasitol. 43:1992;173-176.
    • (1992) Trop. Med. Parasitol. , vol.43 , pp. 173-176
    • Carme, B.1    Yombi, B.2    Bouquety, J.C.3    Plassard, H.4    Nzingoula, S.5    Senga, J.6    Akani, I.7
  • 24
    • 0034212451 scopus 로고    scopus 로고
    • Abnormal blood flow and red blood cell deformability in severe malaria
    • Dondorp A.M., Kager P.A., Vreeken J., White N.J. Abnormal blood flow and red blood cell deformability in severe malaria. Parasitol. Today. 16:2000;228-232.
    • (2000) Parasitol. Today , vol.16 , pp. 228-232
    • Dondorp, A.M.1    Kager, P.A.2    Vreeken, J.3    White, N.J.4
  • 25
    • 0036061692 scopus 로고    scopus 로고
    • The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion
    • Dondorp A.M., Nyanoti M., Kager P.A., Mithwani S., Vreeken J., Marsh K. The role of reduced red cell deformability in the pathogenesis of severe falciparum malaria and its restoration by blood transfusion. Trans. R. Soc. Trop. Med. Hyg. 96:2002;282-286.
    • (2002) Trans. R. Soc. Trop. Med. Hyg. , vol.96 , pp. 282-286
    • Dondorp, A.M.1    Nyanoti, M.2    Kager, P.A.3    Mithwani, S.4    Vreeken, J.5    Marsh, K.6
  • 26
    • 0033659829 scopus 로고    scopus 로고
    • Life-threatening severe malarial anaemia
    • English M. Life-threatening severe malarial anaemia. Trans. R. Soc. Trop. Med. Hyg. 94:2000;585-588.
    • (2000) Trans. R. Soc. Trop. Med. Hyg. , vol.94 , pp. 585-588
    • English, M.1
  • 27
    • 0037045566 scopus 로고    scopus 로고
    • Blood transfusion for severe anaemia in children in a Kenyan hospital
    • English M., Ahmed M., Ngando C., Berkley J., Ross A. Blood transfusion for severe anaemia in children in a Kenyan hospital. Lancet. 359:2002;494-495.
    • (2002) Lancet , vol.359 , pp. 494-495
    • English, M.1    Ahmed, M.2    Ngando, C.3    Berkley, J.4    Ross, A.5
  • 28
    • 0030988904 scopus 로고    scopus 로고
    • Lactic acidosis and oxygen debt in African children with severe anaemia
    • English M., Muambi B., Mithwani S., Marsh K. Lactic acidosis and oxygen debt in African children with severe anaemia. Q. J. Med. 90:1997a;563-569.
    • (1997) Q. J. Med. , vol.90 , pp. 563-569
    • English, M.1    Muambi, B.2    Mithwani, S.3    Marsh, K.4
  • 32
    • 0029850111 scopus 로고    scopus 로고
    • Transfusion for respiratory distress in life-threatening childhood malaria
    • English M., Waruiru C., Marsh K. Transfusion for respiratory distress in life-threatening childhood malaria. Am. J. Trop. Med. Hyg. 55:1996b;525-530.
    • (1996) Am. J. Trop. Med. Hyg. , vol.55 , pp. 525-530
    • English, M.1    Waruiru, C.2    Marsh, K.3
  • 33
    • 0346046221 scopus 로고    scopus 로고
    • HIV and blood transfusion in sub-Saharan Africa
    • Fleming A.F. HIV and blood transfusion in sub-Saharan Africa. Transfus. Sci. 18:1997;167-179.
    • (1997) Transfus. Sci. , vol.18 , pp. 167-179
    • Fleming, A.F.1
  • 34
    • 0022542060 scopus 로고
    • The use of sodium bicarbonate in the therapy of organic acidosis
    • Graf H., Arieff A.I. The use of sodium bicarbonate in the therapy of organic acidosis. Intensive Care Med. 12:1986;285-288.
    • (1986) Intensive Care Med. , vol.12 , pp. 285-288
    • Graf, H.1    Arieff, A.I.2
  • 38
    • 0017273769 scopus 로고
    • The treatment of malaria
    • Hall A.P. The treatment of malaria. Br. Med. J. 1:1976;323-328.
    • (1976) Br. Med. J. , vol.1 , pp. 323-328
    • Hall, A.P.1
  • 39
    • 0017331646 scopus 로고
    • Prediction of morbidity in Hemophilus influenzae meningitis
    • Herson V.C., Todd J.K. Prediction of morbidity in Hemophilus influenzae meningitis. Pediatrics. 59:1977;35-39.
    • (1977) Pediatrics , vol.59 , pp. 35-39
    • Herson, V.C.1    Todd, J.K.2
  • 40
    • 0037426726 scopus 로고    scopus 로고
    • The pathophysiology and treatment of sepsis
    • Hotchkiss R.S., Karl I.E. The pathophysiology and treatment of sepsis. N. Engl. J. Med. 348:2003;138-150.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 138-150
    • Hotchkiss, R.S.1    Karl, I.E.2
  • 41
    • 0024353909 scopus 로고
    • Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria
    • Kern P., Hemmer C.J., Van Damme J., Gruss H.J., Dietrich M. Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated Plasmodium falciparum malaria. Am. J. Med. 87:1989;139-143.
    • (1989) Am. J. Med. , vol.87 , pp. 139-143
    • Kern, P.1    Hemmer, C.J.2    Van Damme, J.3    Gruss, H.J.4    Dietrich, M.5
  • 42
    • 0026514222 scopus 로고
    • Electrolyte abnormalities in critically ill children
    • Khilnani P. Electrolyte abnormalities in critically ill children. Crit. Care Med. 20:1992;241-250.
    • (1992) Crit. Care Med. , vol.20 , pp. 241-250
    • Khilnani, P.1
  • 45
    • 0034984296 scopus 로고    scopus 로고
    • Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction
    • Kumar A., Haery C., Parrillo J.E. Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction. J. Cardiothorac. Vasc. Anesth. 15:2001;364-376.
    • (2001) J. Cardiothorac. Vasc. Anesth. , vol.15 , pp. 364-376
    • Kumar, A.1    Haery, C.2    Parrillo, J.E.3
  • 46
    • 0032513971 scopus 로고    scopus 로고
    • Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria
    • Kurtzhals J.A., Adabayeri V., Goka B.Q., Akanmori B.D., Oliver-Commey J.O., Nkrumah F.K., Behr C., Hviid L. Low plasma concentrations of interleukin 10 in severe malarial anaemia compared with cerebral and uncomplicated malaria. Lancet. 351:1998;1768-1772.
    • (1998) Lancet , vol.351 , pp. 1768-1772
    • Kurtzhals, J.A.1    Adabayeri, V.2    Goka, B.Q.3    Akanmori, B.D.4    Oliver-Commey, J.O.5    Nkrumah, F.K.6    Behr, C.7    Hviid, L.8
  • 48
    • 0034780523 scopus 로고    scopus 로고
    • Antigenic variation at the infected red cell surface in malaria
    • Kyes S., Horrocks P., Newbold C. Antigenic variation at the infected red cell surface in malaria. Annu. Rev. Microbiol. 55:2001;673-707.
    • (2001) Annu. Rev. Microbiol. , vol.55 , pp. 673-707
    • Kyes, S.1    Horrocks, P.2    Newbold, C.3
  • 50
    • 1442280891 scopus 로고
    • Paediatric emergencies
    • Black, D. (Ed.). Butterworths, London
    • Levin, M., 1987. Paediatric emergencies. In: Black, D. (Ed.), Shock. Butterworths, London, pp. 87-116.
    • (1987) Shock , pp. 87-116
    • Levin, M.1
  • 53
    • 0142104467 scopus 로고    scopus 로고
    • Response to volume resuscitation in children with severe malaria
    • Maitland, K., Pamba, A., Newton, C., Levin, M., 2003b. Response to volume resuscitation in children with severe malaria, Pediatr. Crit. Care Med. 4, 426-431.
    • (2003) Pediatr. Crit. Care Med. , vol.4 , pp. 426-431
    • Maitland, K.1    Pamba, A.2    Newton, C.3    Levin, M.4
  • 54
    • 0026591334 scopus 로고
    • Malaria-a neglected disease?
    • Marsh K. Malaria-a neglected disease? Parasitology. 104:1992;S53-S69.
    • (1992) Parasitology , vol.104
    • Marsh, K.1
  • 55
    • 15844363623 scopus 로고    scopus 로고
    • Clinical algorithm for malaria in Africa
    • author reply 1328-1329
    • Marsh K., English M., Peshu N., Crawley J., Snow R. Clinical algorithm for malaria in Africa. Lancet. 347:1996;1327-1328. author reply 1328-1329.
    • (1996) Lancet , vol.347 , pp. 1327-1328
    • Marsh, K.1    English, M.2    Peshu, N.3    Crawley, J.4    Snow, R.5
  • 57
    • 1442305510 scopus 로고    scopus 로고
    • Clinical malaria
    • Perlman, Wahlgren, M. (Eds.). Gordon and Breach Publishers.
    • Marsh, K., 1999. Clinical malaria. In: Perlman, Wahlgren, M. (Eds.), Malaria: Molecular and Clinical Aspects. Gordon and Breach Publishers.
    • (1999) Malaria: Molecular and Clinical Aspects
    • Marsh, K.1
  • 58
    • 0024340659 scopus 로고
    • Clinical features and prognostic indicators in paediatric cerebral malaria: A study of 131 comatose Malawian children
    • Molyneux M.E., Taylor T.E., Wirima J.J., Borgstein A. Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children. Q. J. Med. 71:1989;441-459.
    • (1989) Q. J. Med. , vol.71 , pp. 441-459
    • Molyneux, M.E.1    Taylor, T.E.2    Wirima, J.J.3    Borgstein, A.4
  • 59
    • 0013964930 scopus 로고
    • Neurological manifestations of malaria in children
    • Musoke L.K. Neurological manifestations of malaria in children. East. Afr. Med. J. 43:1966;561-564.
    • (1966) East. Afr. Med. J. , vol.43 , pp. 561-564
    • Musoke, L.K.1
  • 60
    • 0023238774 scopus 로고
    • Bicarbonate therapy for organic acidosis: The case for its continued use
    • Narins, R.G.C., Cohen, J.J., 1987. Bicarbonate therapy for organic acidosis: the case for its continued use, Ann. Intern. Med. 106, 615-618.
    • (1987) Ann. Intern. Med. , vol.106 , pp. 615-618
    • Narins, R.G.C.1    Cohen, J.J.2
  • 64
    • 0031849928 scopus 로고    scopus 로고
    • Severe falciparum malaria in children: Current understanding of pathophysiology and supportive treatment
    • Newton C.R., Krishna S. Severe falciparum malaria in children: current understanding of pathophysiology and supportive treatment. Pharmacol. Ther. 79:1998;1-53.
    • (1998) Pharmacol. Ther. , vol.79 , pp. 1-53
    • Newton, C.R.1    Krishna, S.2
  • 65
    • 0030197975 scopus 로고    scopus 로고
    • Perturbations of cerebral hemodynamics in Kenyans with cerebral malaria
    • Newton C.R., Marsh K., Peshu N., Kirkham F.J. Perturbations of cerebral hemodynamics in Kenyans with cerebral malaria. Pediatr. Neurol. 15:1996;41-49.
    • (1996) Pediatr. Neurol. , vol.15 , pp. 41-49
    • Newton, C.R.1    Marsh, K.2    Peshu, N.3    Kirkham, F.J.4
  • 68
    • 0031758825 scopus 로고    scopus 로고
    • Blood transfusions for severe malaria-related anemia in Africa: A decision analysis
    • Obonyo C.O., Steyerberg E.W., Oloo A.J., Habbema J.D. Blood transfusions for severe malaria-related anemia in Africa: a decision analysis. Am. J. Trop. Med. Hyg. 59:1998;808-812.
    • (1998) Am. J. Trop. Med. Hyg. , vol.59 , pp. 808-812
    • Obonyo, C.O.1    Steyerberg, E.W.2    Oloo, A.J.3    Habbema, J.D.4
  • 70
    • 0025155491 scopus 로고
    • Normalization of plasma arginine vasopressin concentrations when children with meningitis are given maintenance plus replacement fluid therapy
    • Powell K.R., Sugarman L.I., Eskenazi A.E., Woodin K.A., Kays M.A., McCormick K.L., Miller M.E., Sladek C.D. Normalization of plasma arginine vasopressin concentrations when children with meningitis are given maintenance plus replacement fluid therapy. J. Pediatr. 117:1990;515-522.
    • (1990) J. Pediatr. , vol.117 , pp. 515-522
    • Powell, K.R.1    Sugarman, L.I.2    Eskenazi, A.E.3    Woodin, K.A.4    Kays, M.A.5    McCormick, K.L.6    Miller, M.E.7    Sladek, C.D.8
  • 71
    • 0028998232 scopus 로고
    • Application of new sepsis definitions to evaluate outcome of pediatric patients with severe systemic infections
    • Saez-Llorens X., Vargas S., Guerra F., Coronado L. Application of new sepsis definitions to evaluate outcome of pediatric patients with severe systemic infections. Pediatr. Infect. Dis. J. 14:1995;557-561.
    • (1995) Pediatr. Infect. Dis. J. , vol.14 , pp. 557-561
    • Saez-Llorens, X.1    Vargas, S.2    Guerra, F.3    Coronado, L.4
  • 72
    • 0034922481 scopus 로고    scopus 로고
    • The role of cerebral oedema in the pathogenesis of cerebral malaria
    • Sanni L.A. The role of cerebral oedema in the pathogenesis of cerebral malaria. Redox Rep. 6:2001;137-142.
    • (2001) Redox Rep. , vol.6 , pp. 137-142
    • Sanni, L.A.1
  • 73
    • 0029681856 scopus 로고    scopus 로고
    • The systemic inflammatory response: Perspective of human endotoxemia
    • Santos A.A., Wilmore D.W. The systemic inflammatory response: perspective of human endotoxemia. Shock. 6:1996;S50-S56.
    • (1996) Shock , vol.6
    • Santos, A.A.1    Wilmore, D.W.2
  • 76
    • 0027238425 scopus 로고
    • Acid-base status in paediatric Plasmodium falciparum malaria
    • Taylor T.E., Borgstein A., Molyneux M.E. Acid-base status in paediatric Plasmodium falciparum malaria. Q. J. Med. 86:1993;99-109.
    • (1993) Q. J. Med. , vol.86 , pp. 99-109
    • Taylor, T.E.1    Borgstein, A.2    Molyneux, M.E.3
  • 77
    • 0036900560 scopus 로고    scopus 로고
    • Role of proinflammatory and anti-inflammatory cytokines in the immune response to Plasmodium falciparum malaria
    • Torre D., Speranza F., Martegani R. Role of proinflammatory and anti-inflammatory cytokines in the immune response to Plasmodium falciparum malaria. Lancet Infect. Dis. 2:2002;719-720.
    • (2002) Lancet Infect. Dis. , vol.2 , pp. 719-720
    • Torre, D.1    Speranza, F.2    Martegani, R.3
  • 80
    • 0032558323 scopus 로고    scopus 로고
    • Not much progress in treatment of cerebral malaria
    • White N.J. Not much progress in treatment of cerebral malaria. Lancet. 352:1998;594-595.
    • (1998) Lancet , vol.352 , pp. 594-595
    • White, N.J.1
  • 81
    • 0035723404 scopus 로고    scopus 로고
    • Correlation of retinal haemorrhages with brain haemorrhages in children dying of cerebral malaria in Malawi
    • White V.A., Lewallen S., Beare N., Kayira K., Carr R.A., Taylor T.E. Correlation of retinal haemorrhages with brain haemorrhages in children dying of cerebral malaria in Malawi. Trans. R. Soc. Trop. Med. Hyg. 95:2001;618-621.
    • (2001) Trans. R. Soc. Trop. Med. Hyg. , vol.95 , pp. 618-621
    • White, V.A.1    Lewallen, S.2    Beare, N.3    Kayira, K.4    Carr, R.A.5    Taylor, T.E.6
  • 82
    • 0001885268 scopus 로고
    • World Health Organization, Division of Control of Tropical Diseases
    • Severe and complicated malaria, 1990. World Health Organization, Division of Control of Tropical Diseases. Trans. R. Soc. Trop. Med. Hyg. 84, 1-65.
    • (1990) Trans. R. Soc. Trop. Med. Hyg. , vol.84 , pp. 1-65
  • 83
    • 33646461486 scopus 로고    scopus 로고
    • World Health Organization, Communicable Diseases Cluster
    • Severe falciparum malaria, 2000. World Health Organization, Communicable Diseases Cluster. Trans. R. Soc. Trop. Med. Hyg. 94 (Suppl. 1), S1-90.
    • (2000) Trans. R. Soc. Trop. Med. Hyg. , vol.94 , Issue.1 SUPPL.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.