Heat shock protein 27-targeted heptapeptide of the PKCΔ catalytic V5 region sensitizes tumors with radio- and chemoresistance

International Journal of Radiation Oncology Biology Physics

Volumn 80, Issue 1, 2011, Pages 221-230

  Lee, Hae June ^a   Kim, Eun Ho ^a,b   Seo, Woo Duck ^c   Choi, Tae Hyun ^a   Cheon, Gi Jeong ^a   Lee, Yoon Jin ^a   Lee, Yun Sil ^d  

^a Korea Institute of Radiation and Medical Science   (South Korea)

^b Korea University   (South Korea)

^c National Institute of Animal Science   (South Korea)

^d Ewha Womans University   (South Korea)

Author keywords

Heptapeptide; HSP27; PKC V5; Tumor sensitization

Indexed keywords

CANCER CELLS; CASPASE-3; CHEMORESISTANCE; CHEMOSENSITIZATION; CIS-PLATIN; CLONOGENIC SURVIVAL ASSAYS; COMBINED TREATMENT; FLUORESCEIN ISOTHIOCYANATE; HEAT SHOCK PROTEIN; HEPTAPEPTIDES; HSP27; IN-VITRO; IN-VIVO; LUNG CARCINOMA; NUDE MICE; SENSITIZING EFFECTS; WESTERN BLOTTING;

BIOLOGICAL ORGANS; FLOW CYTOMETRY; IONIZING RADIATION; PLATINUM COMPOUNDS; TUMORS;

RADIATION EFFECTS;

CASPASE 3; CISPLATIN; HEAT SHOCK PROTEIN 27; HEPTAPEPTIDE; PHENYLALANYLGLUTAMYLGLUTAMINYLPHENYLALANYLLEUCYLASPARTYLISOLEUCINE; PROTEIN KINASE C DELTA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER RADIOTHERAPY; CHEMOSENSITIZATION; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG POTENTIATION; DRUG PROTEIN BINDING; DRUG TARGETING; HUMAN; HUMAN CELL; IONIZING RADIATION; LUNG CARCINOMA; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RADIOSENSITIZATION; TUMOR XENOGRAFT;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CASPASE 3; CATALYTIC DOMAIN; CELL LINE, TUMOR; CISPLATIN; DRUG RESISTANCE, NEOPLASM; FLOW CYTOMETRY; HSP27 HEAT-SHOCK PROTEINS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM PROTEINS; PEPTIDE FRAGMENTS; PROTEIN KINASE C-DELTA; PROTEIN KINASE INHIBITORS; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79954422840     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2010.11.069     Document Type: Article

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