Structural brain imaging: A window into chronic pain

Neuroscientist

Volumn 17, Issue 2, 2011, Pages 209-220

  May, Arne ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

brain; chronic pain; chronicity; headache; imaging; morphometry; structure; VBM

Indexed keywords

ANTERIOR CINGULATE; BACKACHE; BASAL GANGLION; BRAIN STEM; CHRONIC PAIN; CINGULATE GYRUS; DISEASE COURSE; DISEASE PREDISPOSITION; FACE PAIN; FIBROMYALGIA; FRONTAL CORTEX; FRONTAL GYRUS; GRAY MATTER; HERPES SIMPLEX VIRUS; HIP OSTEOARTHRITIS; HUMAN; HYPOTHALAMUS; INSULA; IRRITABLE COLON; MESENCEPHALON; MIGRAINE; MOTOR CORTEX; NEUROIMAGING; NEUROPATHIC PAIN; OSTEOARTHRITIS; PHANTOM PAIN; PONS; POSTTRAUMATIC HEADACHE; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; TEMPORAL LOBE; THALAMUS;

ANIMALS; BRAIN; BRAIN MAPPING; CHRONIC DISEASE; DIAGNOSTIC IMAGING; HUMANS; NEURAL PATHWAYS; PAIN;

EID: 79953859614     PISSN: 10738584     EISSN: 10894098     Source Type: Journal    
DOI: 10.1177/1073858410396220     Document Type: Review

References (61)

1. Afridi SK, Matharu MS, Lee L., Kaube H., Friston KJ, Frackowiak RS, and others. 2005. A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate. Brain 128: 932-9. (Pubitemid 40516929)
2. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: American Psychiatric Association.
3. Apkarian AV, Sosa Y., Sonty S., Levy RM, Harden RN, Parrish TB, and others. 2004. Chronic back pain is associated with decreased prefrontal and thalamic gray matter density. J Neurosci 24: 10410-5. (Pubitemid 39552626)
4. Blankstein U., Chen J., Diamant NE, Davis KD 2010. Altered brain structure in irritable bowel syndrome: potential contributions of pre-existing and disease-driven factors. Gastroenterology 138: 1783-9.
5. Boyke J., Driemeyer J., Gaser C., Buchel C., May A. 2008. Training-induced brain structure changes in the elderly. J Neurosci 28: 7031-5.
6. Buckalew N., Haut MW, Morrow L., Weiner D. 2008. Chronic pain is associated with brain volume loss in older adults: preliminary evidence. Pain Med 9: 240-8. (Pubitemid 351285420)
7. Burgmer M., Gaubitz M., Konrad C., Wrenger M., Hilgart S., Heuft G., and others. 2009. Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia. Psychosom Med 71: 566-73.
8. Chan ST, Tang KW, Lam KC, Chan LK, Mendola JD, Kwong KK 2004. Neuroanatomy of adult strabismus: a voxel-based morphometric analysis of magnetic resonance structural scans. Neuroimage 22: 986-94. (Pubitemid 38759464)
9. DaSilva AF, Granziera C., Snyder J., Hadjikhani N. 2007. Thickening in the somatosensory cortex of patients with migraine. Neurology 69: 1990-5. (Pubitemid 350145091)
10. Davis KD, Pope G., Chen J., Kwan CL, Crawley AP, Diamant NE 2008. Cortical thinning in IBS: implications for homeostatic, attention, and pain processing. Neurology 70: 153-4.
11. Dettmers C., Adler T., Rzanny R., van Schayck R., Gaser C., Weiss T., and others. 2001. Increased excitability in the primary motor cortex and supplementary motor area in patients with phantom limb pain after upper limb amputation. Neurosci Lett 307: 109-12. (Pubitemid 32568386)
12. Draganski B., Gaser C., Busch V., Schuierer G., Bogdahn U., May A. 2004. Neuroplasticity: changes in grey matter induced by training. Nature 427: 311-2. (Pubitemid 38133650)
13. Draganski B., Gaser C., Kempermann G., Kuhn HG, Winkler J., Buchel C., and others. 2006. Temporal and spatial dynamics of brain structure changes during extensive learning. J Neurosci 26: 6314-7.
14. Draganski B., Moser T., Lummel N., Ganssbauer S., Bogdahn U., Haas F., and others. 2006. Decrease of thalamic gray matter following limb amputation. Neuroimage 31: 951-7. (Pubitemid 43870258)
15. Driemeyer J., Boyke J., Gaser C., Buchel C., and May A. 2008. Changes in gray matter induced by learning-revisited. PLoS One 3: e2669.
16. Duerden EG, Laverdure-Dupont D. 2008. Practice makes cortex. J Neurosci 28: 8655-7.
17. Elbert T., Flor H., Birbaumer N., Knecht S., Hampson S., Larbig W., and others. 1994. Extensive reorganization of the somatosensory cortex in adult humans after nervous system injury. Neuroreport 5: 2593-7.
18. Flor H. 2003. Cortical reorganisation and chronic pain: implications for rehabilitation. J Rehabil Med 41 (Suppl): 66-72. (Pubitemid 36840810)
19. Flor H., Elbert T., Knecht S., Wienbruch C., Pantev C., Birbaumer N., and others. 1995. Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation. Nature 375: 482-4.
20. Florence SL, Taub HB, Kaas JH 1998. Large-scale sprouting of cortical connections after peripheral injury in adult macaque monkeys. Science 282: 1117-21. (Pubitemid 28516240)
21. Gaser C., Schlaug G. 2003. Brain structures differ between musicians and non-musicians. J Neurosci 23: 9240-5. (Pubitemid 37243825)
22. Geha PY, Baliki MN, Harden RN, Bauer WR, Parrish TB, Apkarian AV 2008. The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regions. Neuron 60: 570-81.
23. Granziera C., Dasilva AF, Snyder J., Tuch DS, Hadjikhani N. 2006. Anatomical alterations of the visual motion processing network in migraine with and without aura. PLoS Med 3: e402.
24. Grusser SM, Muhlnickel W., Schaefer M., Villringer K., Christmann C., Koeppe C., and others. 2004. Remote activation of referred phantom sensation and cortical reorganization in human upper extremity amputees. Exp Brain Res 154: 97-102. (Pubitemid 38134643)
25. Grusser SM, Winter C., Muhlnickel W., Denke C., Karl A., Villringer K., and others. 2001. The relationship of perceptual phenomena and cortical reorganization in upper extremity amputees. Neuroscience 102: 263-72. (Pubitemid 32126480)
26. Gustin SM, Wrigley PJ, Siddall PJ, Henderson LA 2009. Brain anatomy changes associated with persistent neuropathic pain following spinal cord injury. Cereb Cortex 20: 1409-19.
27. Gwilym SE, Fillipini N., Douaud G., Carr AJ, Tracey I. 2010. Thalamic atrophy associated with painful osteoarthritis of the hip is reversible after arthroplasty: a longitudinal voxel-based-morphometric study. Arthritis Rheum 62: 2930-40.
28. Hsu MC, Harris RE, Sundgren PC, Welsh RC, Fernandes CR, Clauw DJ, and others. 2009. No consistent difference in gray matter volume between individuals with fibromyalgia and age-matched healthy subjects when controlling for affective disorder. Pain 143: 262-7.
29. Ilg R., Wohlschlager AM, Gaser C., Liebau Y., Dauner R., Woller A., and others. 2008. Gray matter increase induced by practice correlates with task-specific activation: a combined functional and morphometric magnetic resonance imaging study. J Neurosci 28: 4210-5.
30. Jancke L., Koeneke S., Hoppe A., Rominger C., Hanggi J. 2009. The architecture of the golfer's brain. PLoS One 4: e4785.
31. Jones EG, Pons TP 1998. Thalamic and brainstem contributions to large-scale plasticity of primate somatosensory cortex. Science 282: 1121-5. (Pubitemid 28516241)
32. Kim JH, Suh SI, Seol HY, Oh K., Seo WK, Yu SW, and others. 2008. Regional grey matter changes in patients with migraine: a voxel-based morphometry study. Cephalalgia 28: 598-604. (Pubitemid 351614929)
33. Kuchinad A., Schweinhardt P., Seminowicz DA, Wood PB, Chizh BA, Bushnell MC 2007. Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain ? J Neurosci 27: 4004-7. (Pubitemid 46597143)
34. Kwan CL, Diamant NE, Pope G., Mikula K., Mikulis DJ, Davis KD 2005. Abnormal forebrain activity in functional bowel disorder patients with chronic pain. Neurology 65: 1268-77. (Pubitemid 41508222)
35. Lutz J., Jager L., de Quervain D., Krauseneck T., Padberg F., Wichnalek M., and others. 2008. White and gray matter abnormalities in the brain of patients with fibromyalgia: a diffusion-tensor and volumetric imaging study. Arthritis Rheum 58: 3960-9.
36. Matharu MS, Good CD, May A., Bahra A., Goadsby PJ 2003. No change in the structure of the brain in migraine: a voxel-based morphometric study. Eur J Neurol 10: 53-7. (Pubitemid 36114942)
37. May A. 2008. Chronic pain may change the structure of the brain. Pain 137: 7-15.
38. May A. 2009 a. Morphing voxels: the hype around structural imaging of headache patients. Brain 132 (Pt 6). 1419-25.
39. May A. 2009 b. New insights into headache: an update on functional and structural imaging findings. Nat Rev Neurol 5: 199-209.
40. May A., Ashburner J., Buchel C., McGonigle DJ, Friston KJ, Frackowiak RS, and others. 1999. Correlation between structural and functional changes in brain in an idiopathic headache syndrome. Nat Med 5: 836-8. (Pubitemid 29318621)
41. Mendola JD, Conner IP, Roy A., Chan ST, Schwartz TL, Odom JV, and others. 2005. Voxel-based analysis of MRI detects abnormal visual cortex in children and adults with amblyopia. Hum Brain Mapp 25: 222-36. (Pubitemid 40734089)
42. Obermann M., Nebel K., Schumann C., Holle D., Gizewski ER, Maschke M., and others. 2009. Gray matter changes related to chronic posttraumatic headache. Neurology 73: 978-83.
43. Rocca MA, Ceccarelli A., Falini A., Colombo B., Tortorella P., Bernasconi L., and others. 2006. Brain gray matter changes in migraine patients with T2-visible lesions: a 3-T MRI study. Stroke 37: 1765-70. (Pubitemid 44297727)
44. Rodriguez-Raecke R., Niemeier A., Ihle K., Ruether W., May A. 2009. Brain gray matter decrease in chronic pain is the consequence and not the cause of pain. J Neurosci 29: 13746-50.
45. Schmidt-Wilcke T., Ganssbauer S., Neuner T., Bogdahn U., May A. 2008. Subtle grey matter changes between migraine patients and healthy controls. Cephalalgia 28: 1-4. (Pubitemid 350212641)
46. Schmidt-Wilcke T., Hierlmeier S., Leinisch E. 2010. Altered regional brain morphology in patients with chronic facial pain. Headache 50: 1278-85.
47. Schmidt-Wilcke T., Leinisch E., Ganssbauer S., Draganski B., Bogdahn U., Altmeppen J., and others. 2006. Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients. Pain 125: 89-97. (Pubitemid 44498967)
48. Schmidt-Wilcke T., Leinisch E., Straube A., Kampfe N., Draganski B., Diener HC, and others. 2005. Gray matter decrease in patients with chronic tension type headache. Neurology 65: 1483-6. (Pubitemid 41552788)
49. Schmidt-Wilcke T., Luerding R., Weigand T., Jurgens T., Schuierer G., Leinisch E., and others. 2007. Striatal grey matter increase in patients suffering from fibromyalgia: a voxel-based morphometry study. Pain 132 (Suppl 1): S109-16.
50. Schmitz N., Admiraal-Behloul F., Arkink EB, Kruit MC, Schoonman GG, Ferrari MD, and others. 2008. Attack frequency and disease duration as indicators for brain damage in migraine. Headache 48: 1044-55. (Pubitemid 351952082)
51. Schweinhardt P., Kuchinad A., Pukall CF, Bushnell MC 2008. Increased gray matter density in young women with chronic vulvar pain. Pain 140: 411-9.
52. Seminowicz DA, Labus JS, Bueller JA, Tillisch K., Naliboff BD, Bushnell MC, and others. 2010. Regional gray matter density changes in brains of patients with irritable bowel syndrome. Gastroenterology 139: 48-57.
53. Teutsch S., Herken W., Bingel U., Schoell E., May A. 2008. Changes in brain gray matter due to repetitive painful stimulation. Neuroimage 42: 845-9.
54. Valet M., Gundel H., Sprenger T., Sorg C., Muhlau M., Zimmer C., and others. 2009. Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study. Psychosom Med 71: 49-56.
55. Valfre W., Rainero I., Bergui M., Pinessi L. 2008. Voxel-based morphometry reveals gray matter abnormalities in migraine. Headache 48: 109-17.
56. Vartiainen N., Kallio-Laine K., Hlushchuk Y., Kirveskari E., Seppanen M., Autti H., and others. 2009. Changes in brain function and morphology in patients with recurring herpes simplex virus infections and chronic pain. Pain 144: 200-8.
57. Wood PB, Glabus MF, Simpson R., Patterson JC II. 2009. Changes in gray matter density in fibromyalgia: correlation with dopamine metabolism. J Pain 10: 609-18.
58. Woolf CJ, Salter MW 2000. Neuronal plasticity: increasing the gain in pain. Science 288: 1765-9.
59. Wrigley PJ, Gustin SM, Macey PM, Nash PG, Gandevia SC, Macefield VG, and others. 2008. Anatomical changes in human motor cortex and motor pathways following complete thoracic spinal cord injury. Cereb Cortex 19: 224-32.
60. Wrigley PJ, Press SR, Gustin SM, Macefield VG, Gandevia SC, Cousins MJ, and others. 2009. Neuropathic pain and primary somatosensory cortex reorganization following spinal cord injury. Pain 141: 52-9.
61. Younger JW, Shen YF, Goddard G., Mackey SC 2010. Chronic myofascial temporomandibular pain is associated with neural abnormalities in the trigeminal and limbic systems. Pain 149: 222-8.