White and gray matter abnormalities in the brain of patients with fibromyalgia: A diffusion-tensor and volumetric imaging study

Arthritis and Rheumatism

Volumn 58, Issue 12, 2008, Pages 3960-3969

  Lutz, Jürgen ^a   Jäger, Lorenz ^a   De Quervain, Dominique ^b   Krauseneck, Till ^a   Padberg, Frank ^a   Wichnalek, Martina ^a   Beyer, Antje ^a   Stahl, Robert ^a   Zirngibl, Ben ^a   Morhard, Dominik ^a   Reiser, Maximilian ^a   Schelling, Gustav ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AFFECT; AGED; AMYGDALOID NUCLEUS; ANISOTROPY; ANXIETY; ARTICLE; BRAIN SIZE; BRAIN TISSUE; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FATIGUE; FEMALE; FIBROMYALGIA; GRAY MATTER; HIPPOCAMPUS; HOMEOSTASIS; HUMAN; INSULA; MEMORY; MORPHOMETRICS; MOTIVATION; NERVE CELL NETWORK; NUCLEAR MAGNETIC RESONANCE IMAGING; PAIN; PAIN ASSESSMENT; PERCEPTION; PHYSICAL DISEASE; PRIORITY JOURNAL; SENSORY SYSTEM; STRESS; THALAMOCORTICAL TRACT; THALAMUS; WHITE MATTER;

ADULT; AGED; AMYGDALA; BRAIN; DIFFUSION MAGNETIC RESONANCE IMAGING; EMOTIONS; FEMALE; GYRUS CINGULI; HIPPOCAMPUS; HUMANS; MEMORY; MIDDLE AGED; NERVE FIBERS, MYELINATED; NEURONS; PAIN; SOMATOSENSORY CORTEX; STRESS, PSYCHOLOGICAL; THALAMUS;

EID: 57349170177     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24070     Document Type: Article

References (52)

1. Abeles AM, Pillinger MH, Solitar BM, Abeles M. Narrative review: the pathophysiology of fibromyalgia. Ann Intern Med 2007;146:726-34.
2. Williams DA, Gracely RH. Biology and therapy of fibromyalgia: functional magnetic resonance imaging findings in fibromyalgia. Arthritis Res Ther 2006;8:224.
3. Sundgren PC, Dong Q, Gomez-Hassan D, Mukherji SK, Maly P, Welsh R. Diffusion tensor imaging of the brain: review of clinical applications. Neuroradiology 2004;46:339-50.
4. Basser PJ, Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson B 1996;111:209-19.
5. Bhagat YA, Beaulieu C. Diffusion anisotropy in subcortical white matter and cortical gray matter: changes with aging and the role of CSF-suppression. J Magn Reson Imaging 2004;20:216-27.
6. Weir PT, Harlan GA, Nkoy FL, Jones SS, Hegmann KT, Gren LH, et al. The incidence of fibromyalgia and its associated comorbidities: a population-based retrospective cohort study based on International Classification of Diseases, 9th Revision codes. J Clin Rheumatol 2006;12:124-8.
7. Raphael KG, Janal MN, Nayak S. Comorbidity of fibromyalgia and posttraumatic stress disorder symptoms in a community sample of women. Pain Med 2004;5:33-41.
8. Wolfe F, Smythe HA, Yunus MB, Bennett RM, Bombardier C, Goldenberg DL, et al. The American College of Rheumatology 1990 criteria for the classification of fibromyalgia: report of the Multicenter Criteria Committee. Arthritis Rheum 1990;33:160-72.
9. Offenbaecher M, Waltz M, Schoeps P. Validation of a German version of the Fibromyalgia Impact Questionnaire (FIQ-G). J Rheumatol 2000;27:1984-8.
10. Stoll C, Kapfhammer HP, Haller H, Briegel J, Krauseneck T, Durst K, et al. Sensitivity and specificity of a screening test to document traumatic experiences and to diagnose post-traumatic stress disorder in patients after intensive care treatment. Intensive Care Med 1999;25:697-704.
11. Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy [published erratum appears in Magn Reson Med 1997;37:972]. Magn Reson Med 1996;36:893-906.
12. Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000;11:805-21.
13. Aleman-Gomez Y, Melie-Garcia L, Valdes-Hernandez P. IBASPM: toolbox for automatic parcellation of brain structures. Presented at the 12th Annual Meeting of the Organization for Human Brain Mapping, June 11-15, 2006, Florence, Italy. Available in NeuroImage 2000;27 (No. 1).
14. Schmidt-Wilcke T, Leinisch E, Straube A, Kampfe N, Draganski B, Diener HC, et al. Gray matter decrease in patients with chronic tension type headache. Neurology 2005;65:1483-6.
15. Schmidt-Wilcke T, Leinisch E, Ganssbauer S, Draganski B, Bogdahn U, Altmeppen J, et al. Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients. Pain 2006;125:89-97.
16. Hadjipavlou G, Dunckley P, Behrens TE, Tracey I. Determining anatomical connectivities between cortical and brainstem pain processing regions in humans: a diffusion tensor imaging study in healthy controls. Pain 2006;123:169-78.
17. Sundgren PC, Petrou M, Harris RE, Fan X, Foerster B, Mehrotra N, et al. Diffusion-weighted and diffusion tensor imaging in fibromyalgia patients: a prospective study of whole brain diffusivity, apparent diffusion coefficient, and fraction anisotropy in different regions of the brain and correlation with symptom severity. Acad Radiol 2007;14:839-46.
18. DaSilva AF, Granziera C, Tuch DS, Snyder J, Vincent M, Hadjikhani N. Interictal alterations of the trigeminal somatosensory pathway and periaqueductal gray matter in migraine. Neuroreport 2007;18:301-5.
19. Kuchinad A, Schweinhardt P, Seminowicz DA, Wood PB, Chizh BA, Bushnell CB. Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain? J Neurosci 2007;27:4004-7.
20. Schmidt-Wilcke T, Luerding R, Weigand T, Jurgens T, Schuierer G, Leinisch E, et al. Striatal grey matter increase in patients suffering from fibromyalgia: a voxel-based morphometry study. Pain 2007;132 Suppl 1:S109-16.
21. Okada T, Tanaka M, Kuratsune H, Watanabe Y, Sadato N. Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome. BMC Neurol 2004;4:14.
22. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, et al. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 2002;5:1242-7.
23. Ota M, Obata T, Akine Y, Ito H, Matsumoto R, Ikehira H, et al. Laterality and aging of thalamic subregions measured by diffusion tensor imaging. Neuroreport 2007;18:1071-5.
24. Gilbert AR, Rosenberg DR, Harenski K, Spencer S, Sweeney JA, Keshavan MS. Thalamic volumes in patients with first-episode schizophrenia. Am J Psychiatry 2001;158:618-24.
25. Croft P, Schollum J, Silman A. Population study of tender point counts and pain as evidence of fibromyalgia. BMJ 1994;309:696-9.
26. Gracely RH, Petzke F, Wolf JM, Clauw DJ. Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgia. Arthritis Rheum 2002;46:1333-43.
27. Craig AD, Chen K, Bandy D, Reiman EM. Thermosensory activation of insular cortex. Nat Neurosci 2000;3:184-90.
28. Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ. Neural systems supporting interoceptive awareness. Nat Neurosci 2004;7:189-95.
29. Singer T, Seymour B, O'Doherty J, Kaube H, Dolan RJ, Frith CD. Empathy for pain involves the affective but not sensory components of pain. Science 2004;303:1157-62.
30. Brooks J, Tracey I. From nociception to pain perception: imaging the spinal and supraspinal pathways. J Anat 2005;207:19-33.
31. Fulbright RK, Troche CJ, Skudlarski P, Gore JC, Wexler BE. Functional MR imaging of regional brain activation associated with the affective experience of pain. AJR Am J Roentgenol 2001;177:1205-10.
32. D'Argembeau A, Ruby P, Collette F, Degueldre C, Balteau E, Luxen A, et al. Distinct regions of the medial prefrontal cortex are associated with self-referential processing and perspective taking. J Cogn Neurosci 2007;19:935-44.
33. Gracely RH, Geisser ME, Giesecke T, Grant MA, Petzke F, Williams DA, et al. Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain 2004;127:835-43.
34. Burton AK, Tillotson KM, Main CJ, Hollis S. Psychosocial predictors of outcome in acute and subchronic low back trouble. Spine 1995;20:722-8.
35. Mease P, Arnold LM, Bennett R, Boonen A, Buskila D, Carville S, et al. Fibromyalgia syndrome. J Rheumatol 2007;34:1415-25.
36. De Lange FP, Kalkman JS, Bleijenberg G, Hagoort P, van der Meer JW, Toni I. Gray matter volume reduction in the chronic fatigue syndrome. Neuroimage 2005;26:777-81.
37. De Lange FP, Kalkman JS, Bleijenberg G, Hagoort P, van der Werf SP, van der Meer JW, et al. Neural correlates of the chronic fatigue syndrome: an fMRI study. Brain 2004;127:1948-57.
38. Seitz RJ, Nickel J, Azari NP. Functional modularity of the medial prefrontal cortex: involvement in human empathy. Neuropsychology 2006;20:743-51.
39. Thieme K, Turk DC, Flor H. Comorbid depression and anxiety in fibromyalgia syndrome: relationship to somatic and psychosocial variables. Psychosom Med 2004;66:837-44.
40. Schulkin J. Angst and the amygdala. Dialogues Clin Neurosci 2006;8:407-16.
41. Abe O, Yamasue H, Kasai K, Yamada H, Aoki S, Iwanami A, et al. Voxel-based diffusion tensor analysis reveals aberrant anterior cingulum integrity in posttraumatic stress disorder due to terrorism. Psychiatry Res 2006;146:231-42.
42. Gilboa A, Shalev AY, Laor L, Lester H, Louzoun Y, Chisin R, et al. Functional connectivity of the prefrontal cortex and the amygdala in posttraumatic stress disorder. Biol Psychiatry 2004;55:263-72.
43. Gilbertson MW, Shenton ME, Ciszewski A, Kasai K, Lasko NB, Orr SP, et al. Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma. Nat Neurosci 2002;5:1242-7.
44. Karl A, Schaefer M, Malta LS, Dorfel D, Rohleder N, Werner A. A meta-analysis of structural brain abnormalities in PTSD. Neurosci Biobehav Rev 2006;30:1004-31.
45. Lanius RA, Williamson PC, Densmore M, Boksman K, Gupta MA, Neufeld RW, et al. Neural correlates of traumatic memories in posttraumatic stress disorder: a functional MRI investigation. Am J Psychiatry 2001;158:1920-2.
46. Lanius RA, Williamson PC, Hopper J, Densmore M, Boksman K, Gupta MA, et al. Recall of emotional states in posttraumatic stress disorder: an fMRI investigation. Biol Psychiatry 2003;53:204-10.
47. Mountz JM, Bradley LA, Modell JG, Alexander RW, Triana-Alexander M, Aaron LA, et al. Fibromyalgia in women: abnormalities of regional cerebral blood flow in the thalamus and the caudate nucleus are associated with low pain threshold levels. Arthritis Rheum 1995;38:926-38.
48. Davis KD. The neural circuitry of pain as explored with functional MRI. Neurol Res 2000;22:313-7.
49. Geuze E, Westenberg HG, Jochims A, de Kloet CS, Bohus M, Vermetten E, et al. Altered pain processing in veterans with posttraumatic stress disorder. Arch Gen Psychiatry 2007;64:76-85.
50. Staud R, Rodriguez ME. Mechanisms of disease: pain in fibromyalgia syndrome. Nat Clin Pract Rheumatol 2006;2:90-8.
51. Stoeter P, Bauermann T, Nickel R, Corluka L, Gawehn J, Vucurevic G, et al. Cerebral activation in patients with somatoform pain disorder exposed to pain and stress: an fMRI study. Neuroimage 2007;36:418-30.
52. Bohr TW. Fibromyalgia syndrome and myofascial pain syndrome: do they exist? Neurol Clin 1995;13:365-84.