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Volumn 17, Issue 5, 2011, Pages 398-404

Desirability function combining metabolic stability and functionality of peptides

Author keywords

opioid receptor peptides; Blood brain barrier; Desirability; Metabolic stability; SPECT medical imaging

Indexed keywords

DERMORPHIN; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLARGINYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; IODINE 123; OPIATE PEPTIDE; PEPTIDE DERIVATIVE;

EID: 79953795025     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.1323     Document Type: Article
Times cited : (12)

References (40)
  • 1
    • 34248994895 scopus 로고    scopus 로고
    • New chemotactic dimeric peptides show high affinity and potency at the human formylpeptide receptor
    • Spisani S, Fraulini A, Varani K, Falzarano S, Cavicchioni G. New chemotactic dimeric peptides show high affinity and potency at the human formylpeptide receptor. Eur. J. Pharmacol. 2007; 567: 171-176.
    • (2007) Eur. J. Pharmacol. , vol.567 , pp. 171-176
    • Spisani, S.1    Fraulini, A.2    Varani, K.3    Falzarano, S.4    Cavicchioni, G.5
  • 2
    • 27144511213 scopus 로고    scopus 로고
    • Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban
    • Manning M, Cheng LL, Stoev S, Wo NC, Chan WY, Szeto HH, Durroux T, Mouillac B, Barberis C. Design of peptide oxytocin antagonists with strikingly higher affinities and selectivities for the human oxytocin receptor than atosiban. J. Pept. Sci. 2005; 11: 593-608.
    • (2005) J. Pept. Sci. , vol.11 , pp. 593-608
    • Manning, M.1    Cheng, L.L.2    Stoev, S.3    Wo, N.C.4    Chan, W.Y.5    Szeto, H.H.6    Durroux, T.7    Mouillac, B.8    Barberis, C.9
  • 3
    • 25644444563 scopus 로고    scopus 로고
    • Development of simplified vasoactive intestinal peptide analogs with receptor selectivity and stability for human vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptors
    • Igarashi H, Ito T, Mantey SA, Pradhan TK, Hou W, Coy DH, Jensen RT. Development of simplified vasoactive intestinal peptide analogs with receptor selectivity and stability for human vasoactive intestinal peptide/pituitary adenylate cyclase-activating polypeptide receptors. J. Pharmacol. Exp. Ther. 2005; 315: 370-381.
    • (2005) J. Pharmacol. Exp. Ther. , vol.315 , pp. 370-381
    • Igarashi, H.1    Ito, T.2    Mantey, S.A.3    Pradhan, T.K.4    Hou, W.5    Coy, D.H.6    Jensen, R.T.7
  • 4
    • 34547662365 scopus 로고    scopus 로고
    • Comparison of opioid receptor binding in horse, guinea pig, and rat cerebral cortex and cerebellum
    • Thomasy SM, Moeller BC, Stanley SD. Comparison of opioid receptor binding in horse, guinea pig, and rat cerebral cortex and cerebellum. Vet. Anaesth. Analg. 2007; 34: 351-358.
    • (2007) Vet. Anaesth. Analg. , vol.34 , pp. 351-358
    • Thomasy, S.M.1    Moeller, B.C.2    Stanley, S.D.3
  • 5
    • 77952320541 scopus 로고    scopus 로고
    • Mutagenesis studies of neuropeptide S identify a suitable peptide tracer for neuropeptide S receptor binding studies and peptides selectively activating the I107 variant of human neuropeptide S receptor
    • Nepomuceno D, Sutton S, Yu J, Zhu J, Liu C, Lovenberg T, Bonaventure P. Mutagenesis studies of neuropeptide S identify a suitable peptide tracer for neuropeptide S receptor binding studies and peptides selectively activating the I107 variant of human neuropeptide S receptor. Eur. J. Pharmacol. 2010; 635: 27-33.
    • (2010) Eur. J. Pharmacol. , vol.635 , pp. 27-33
    • Nepomuceno, D.1    Sutton, S.2    Yu, J.3    Zhu, J.4    Liu, C.5    Lovenberg, T.6    Bonaventure, P.7
  • 6
    • 0344269350 scopus 로고    scopus 로고
    • Interaction of agonist peptide [3H]Tyr-Ala-Phe-Phe-NH2 with [mu]-opioid receptor in rat brain and CHO-[mu]/1 cell line
    • Spetea M, Ötvös F, Tóth G, Nguyen TMD, Schiller PW, Vogel Z, Borsodi A. Interaction of agonist peptide [3H]Tyr-Ala-Phe-Phe-NH2 with [mu]-opioid receptor in rat brain and CHO-[mu]/1 cell line. Peptides 1998; 19: 1091-1098.
    • (1998) Peptides , vol.19 , pp. 1091-1098
    • Spetea, M.1    Ötvös, F.2    Tóth, G.3    Nguyen, T.M.D.4    Schiller, P.W.5    Vogel, Z.6    Borsodi, A.7
  • 8
    • 1542466530 scopus 로고    scopus 로고
    • The chemistry of the opioid receptor binding sites
    • Medzihradszky K. The chemistry of the opioid receptor binding sites. J. Pept. Sci. 2003; 9: 333-353.
    • (2003) J. Pept. Sci. , vol.9 , pp. 333-353
    • Medzihradszky, K.1
  • 9
    • 0035292828 scopus 로고    scopus 로고
    • Delivery of peptides and proteins through the blood-brain barrier
    • Bickel U, Yoshikawa T, Pardridge WM. Delivery of peptides and proteins through the blood-brain barrier. Adv. Drug Delivery Rev. 2001; 46: 247-279.
    • (2001) Adv. Drug Delivery Rev. , vol.46 , pp. 247-279
    • Bickel, U.1    Yoshikawa, T.2    Pardridge, W.M.3
  • 12
    • 0030996655 scopus 로고    scopus 로고
    • Peptide delivery into the central nervous system: Invasive, physiological and chemical approaches
    • Prokai L. Peptide delivery into the central nervous system: Invasive, physiological and chemical approaches. Expert Opin. Ther. Pat. 1997; 7: 233-245.
    • (1997) Expert Opin. Ther. Pat. , vol.7 , pp. 233-245
    • Prokai, L.1
  • 14
    • 0033973460 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier
    • Kniesel U, Wolburg H. Tight junctions of the blood-brain barrier. Cell. Mol. Neurobiol. 2000; 20: 57-76.
    • (2000) Cell. Mol. Neurobiol. , vol.20 , pp. 57-76
    • Kniesel, U.1    Wolburg, H.2
  • 15
    • 33645420927 scopus 로고    scopus 로고
    • Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin
    • Pan WH, Tu H, Kastin AJ. Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides 2006; 27: 911-916.
    • (2006) Peptides , vol.27 , pp. 911-916
    • Pan, W.H.1    Tu, H.2    Kastin, A.J.3
  • 16
    • 0021287899 scopus 로고
    • Evidence that [125I]N-Tyr-delta sleep-inducing peptide crosses the blood-brain barrier by a non-competitive mechanism
    • Banks WA, Kastin AJ, Coy DH. Evidence that [125I]N-Tyr-delta sleep-inducing peptide crosses the blood-brain barrier by a non-competitive mechanism. Brain Res. 1984; 301: 201-207.
    • (1984) Brain Res. , vol.301 , pp. 201-207
    • Banks, W.A.1    Kastin, A.J.2    Coy, D.H.3
  • 17
    • 0036842080 scopus 로고    scopus 로고
    • Radiolabeled peptides in the diagnosis and therapy of oncological diseases
    • Weiner RE, Thakur ML. Radiolabeled peptides in the diagnosis and therapy of oncological diseases. Appl. Radiat. Isot. 2002; 57: 749-763.
    • (2002) Appl. Radiat. Isot. , vol.57 , pp. 749-763
    • Weiner, R.E.1    Thakur, M.L.2
  • 18
    • 33750932324 scopus 로고    scopus 로고
    • Synthesis, radiolabeling and receptor binding of [H-3][(1S,2R)ACPC(2)]endomorphin-2
    • Keresztes A, Toth G, Fulop F, Szucs M. Synthesis, radiolabeling and receptor binding of [H-3][(1S, 2R)ACPC(2)]endomorphin-2. Peptides 2006; 27: 3315-3321.
    • (2006) Peptides , vol.27 , pp. 3315-3321
    • Keresztes, A.1    Toth, G.2    Fulop, F.3    Szucs, M.4
  • 20
    • 0036786475 scopus 로고    scopus 로고
    • Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II
    • Hau VS, Huber JD, Campos CR, Lipkowski AW, Misicka A, Davis TP. Effect of guanidino modification and proline substitution on the in vitro stability and blood-brain barrier permeability of endomorphin II. J. Pharm. Sci. 2002; 91: 2140-2149.
    • (2002) J. Pharm. Sci. , vol.91 , pp. 2140-2149
    • Hau, V.S.1    Huber, J.D.2    Campos, C.R.3    Lipkowski, A.W.4    Misicka, A.5    Davis, T.P.6
  • 22
    • 0035047501 scopus 로고    scopus 로고
    • In vitro metabolism of opioid tetrapeptide agonists in various tissues and subcellular fractions from rats
    • Krondahl E, von Euler-Chelpin H, Orzechowski A, Ekström G, Lennernäs H. In vitro metabolism of opioid tetrapeptide agonists in various tissues and subcellular fractions from rats. Peptides 2001; 22: 613-621.
    • (2001) Peptides , vol.22 , pp. 613-621
    • Krondahl, E.1    von Euler-Chelpin, H.2    Orzechowski, A.3    Ekström, G.4    Lennernäs, H.5
  • 23
    • 2142658722 scopus 로고    scopus 로고
    • New trends in the development of opioid peptide analogues as advanced remedies for pain relief
    • Gentilucci L. New trends in the development of opioid peptide analogues as advanced remedies for pain relief. Curr. Top. Med. Chem. 2004; 4: 19-38.
    • (2004) Curr. Top. Med. Chem. , vol.4 , pp. 19-38
    • Gentilucci, L.1
  • 24
    • 33947203944 scopus 로고    scopus 로고
    • Novel glycosylated (LyS(7))-dermorphin analogues: synthesis, biological activity and conformational investigations
    • Biondi L, Filira F, Giannini E, Gobbo M, Lattanzi R, Negri L, Rocchi R. Novel glycosylated (LyS(7))-dermorphin analogues: synthesis, biological activity and conformational investigations. J. Pept. Sci. 2007; 13: 179-189.
    • (2007) J. Pept. Sci. , vol.13 , pp. 179-189
    • Biondi, L.1    Filira, F.2    Giannini, E.3    Gobbo, M.4    Lattanzi, R.5    Negri, L.6    Rocchi, R.7
  • 26
    • 77952544460 scopus 로고    scopus 로고
    • In vitro human brain methionine-enkephalin metabolism
    • Mosnaim AD, Puente J, Tse R, Wolf ME. In vitro human brain methionine-enkephalin metabolism. FASEB J. 2005; 19: A509-A509.
    • (2005) FASEB J. , vol.19
    • Mosnaim, A.D.1    Puente, J.2    Tse, R.3    Wolf, M.E.4
  • 27
    • 52049107373 scopus 로고    scopus 로고
    • In vitro metabolic stability of obestatin: kinetics and identification of cleavage products
    • Vergote V, Van Dorpe S, Peremans K, Burvenich C, De Spiegeleer B. In vitro metabolic stability of obestatin: kinetics and identification of cleavage products. Peptides 2008; 29: 1740-1748.
    • (2008) Peptides , vol.29 , pp. 1740-1748
    • Vergote, V.1    Van Dorpe, S.2    Peremans, K.3    Burvenich, C.4    De Spiegeleer, B.5
  • 28
    • 77952545323 scopus 로고    scopus 로고
    • Analytical characterization and comparison of the blood-brain barrier permeability of eight opioid peptides
    • Van Dorpe S, Adriaens A, Polis I, Peremans K, Van Bocxlaer J, De Spiegeleer B. Analytical characterization and comparison of the blood-brain barrier permeability of eight opioid peptides. Peptides 2010; 31: 1390-1399.
    • (2010) Peptides , vol.31 , pp. 1390-1399
    • Van Dorpe, S.1    Adriaens, A.2    Polis, I.3    Peremans, K.4    Van Bocxlaer, J.5    De Spiegeleer, B.6
  • 29
    • 0025772704 scopus 로고
    • Multiple-criteria optimization
    • Deming SN. Multiple-criteria optimization. J. Chromatogr. 1991; 550: 15-25.
    • (1991) J. Chromatogr. , vol.550 , pp. 15-25
    • Deming, S.N.1
  • 30
    • 0000432952 scopus 로고
    • Simultaneous-optimization of several response variables
    • Derringer G, Suich R. Simultaneous-optimization of several response variables. J. Qual. Technol. 1980; 12: 214-219.
    • (1980) J. Qual. Technol. , vol.12 , pp. 214-219
    • Derringer, G.1    Suich, R.2
  • 32
    • 77954814751 scopus 로고    scopus 로고
    • Evolving molecules using multi-objective optimization: applying to ADME/Tox
    • Ekins S, Honeycutt JD, Metz JT. Evolving molecules using multi-objective optimization: applying to ADME/Tox. Drug Discov. Today 2010; 15: 451-460.
    • (2010) Drug Discov. Today , vol.15 , pp. 451-460
    • Ekins, S.1    Honeycutt, J.D.2    Metz, J.T.3
  • 33
    • 41849122633 scopus 로고    scopus 로고
    • Impurity profiling quality control testing of synthetic peptides using liquid chromatography-photodiode array-fluorescence and liquid chromatography-electrospray ionization-mass spectrometry: the obestatin case
    • De Spiegeleer B, Vergote V, Pezeshki A, Peremans K, Burvenich C. Impurity profiling quality control testing of synthetic peptides using liquid chromatography-photodiode array-fluorescence and liquid chromatography-electrospray ionization-mass spectrometry: the obestatin case. Anal. Biochem. 2008; 376: 229-234.
    • (2008) Anal. Biochem. , vol.376 , pp. 229-234
    • De Spiegeleer, B.1    Vergote, V.2    Pezeshki, A.3    Peremans, K.4    Burvenich, C.5
  • 34
    • 30444452836 scopus 로고    scopus 로고
    • On the rounding rules for logarithmic and exponential operations
    • Chen WD, Lee W, Mulliss CL. On the rounding rules for logarithmic and exponential operations. Chin. J. Phys. 2005; 43: 1017-1034.
    • (2005) Chin. J. Phys. , vol.43 , pp. 1017-1034
    • Chen, W.D.1    Lee, W.2    Mulliss, C.L.3
  • 35
    • 20444480221 scopus 로고    scopus 로고
    • Simultaneous optimization of the resolution and analysis time in micellar liquid chromatography of phenyl thiohydantoin amino acids using Derringer's desirability function
    • Safa F, Hadjmohammadi MR. Simultaneous optimization of the resolution and analysis time in micellar liquid chromatography of phenyl thiohydantoin amino acids using Derringer's desirability function. J. Chromatogr., A 2005; 1078: 42-50.
    • (2005) J. Chromatogr., A , vol.1078 , pp. 42-50
    • Safa, F.1    Hadjmohammadi, M.R.2
  • 36
    • 0002410331 scopus 로고
    • A balancing act-optimizing a product's properties
    • Derringer GC. A balancing act-optimizing a product's properties. Qual. Prog. 1994; 27: 51-58.
    • (1994) Qual. Prog. , vol.27 , pp. 51-58
    • Derringer, G.C.1
  • 37
    • 70849130984 scopus 로고    scopus 로고
    • Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action
    • Aldrich JV, Patkar KA, McLaughlin JP. Zyklophin, a systemically active selective kappa opioid receptor peptide antagonist with short duration of action. Proc. Natl. Acad. Sci. U.S.A. 2009; 106: 18396-18401.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 18396-18401
    • Aldrich, J.V.1    Patkar, K.A.2    McLaughlin, J.P.3
  • 38
    • 40249111499 scopus 로고    scopus 로고
    • [Dmt(1), D-1-Nal(3)]morphiceptin, a novel opioid peptide analog with high analgesic activity
    • Fichna J, Do-Rego JC, Chung NN, Costentin J, Schiller PW, Janecka A. [Dmt(1), D-1-Nal(3)]morphiceptin, a novel opioid peptide analog with high analgesic activity. Peptides 2008; 29: 633-638.
    • (2008) Peptides , vol.29 , pp. 633-638
    • Fichna, J.1    Do-Rego, J.C.2    Chung, N.N.3    Costentin, J.4    Schiller, P.W.5    Janecka, A.6
  • 40
    • 70549106508 scopus 로고    scopus 로고
    • Synthesis and pharmacological properties of a new fluorescent opioid peptide analog
    • Lukowiak M, Kosson P, Hennink WE, Lipikowski AW. Synthesis and pharmacological properties of a new fluorescent opioid peptide analog. Pharmacol. Rep. 2009; 61: 727-731.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 727-731
    • Lukowiak, M.1    Kosson, P.2    Hennink, W.E.3    Lipikowski, A.W.4


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