Novel glycosylated (Lys7)-dermorphin analogues: Synthesis, biological activity and conformational investigations

Journal of Peptide Science

Volumn 13, Issue 3, 2007, Pages 179-189

  Biondi, Laura ^a   Filira, Fernando ^a   Giannini, Elisa ^b   Gobbo, Marina ^a   Lattanzi, Roberta ^b   Negri, Lucia ^b   Rocchi, Raniero ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Biological activity; Conformational investigations; Dermorphin; Glycopeptides; Opioid peptides; Peptide synthesis

Indexed keywords

ACETIC ACID DERIVATIVE; ALANINE; AMINE; ANALGESIC AGENT; DERMORPHIN; DERMORPHIN DERIVATIVE; GLUCOSE DERIVATIVE; GLYCINE; HYDROXYL GROUP; HYDROXYPROLINE; LYSINE DERIVATIVE; PHENYLALANINE; PROLINE; TYROSINE;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GLYCOSYLATION; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DETERMINATION; RAT; SINGLE DRUG DOSE; TAIL FLICK TEST;

AMINO ACID SEQUENCE; ANALGESICS; ANIMALS; CIRCULAR DICHROISM; GLYCOPEPTIDES; GLYCOSYLATION; GUINEA PIGS; MALE; MYENTERIC PLEXUS; OPIOID PEPTIDES; PAIN MEASUREMENT; RATS; RECEPTORS, OPIOID, MU; SPECTROPHOTOMETRY, INFRARED; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 33947203944     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.829     Document Type: Article

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