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Volumn 164, Issue 2, 2011, Pages 236-247

Activation of natural killer T cells by α-carba-GalCer (RCAI-56), a novel synthetic glycolipid ligand, suppresses murine collagen-induced arthritis

Author keywords

Collagen induced arthritis; Glycolipid ligand; Natural killer T cells; Th1; Th17

Indexed keywords

ALPHA CARBA GALCER; ALPHA INTERFERON; COLLAGEN TYPE 2; GALACTOSYLCERAMIDE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 23; INTERLEUKIN 6; RCAI 56; UNCLASSIFIED DRUG;

EID: 79953785705     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2011.04369.x     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 0025304539 scopus 로고
    • Rheumatoid arthritis. Pathophysiology and implications for therapy
    • Harris ED Jr. Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990; 322:1277-89.
    • (1990) N Engl J Med , vol.322 , pp. 1277-1289
    • Harris Jr, E.D.1
  • 2
    • 0034888885 scopus 로고    scopus 로고
    • The genetic and immunopathological processes underlying collagen-induced arthritis
    • Luross JA, Williams NA. The genetic and immunopathological processes underlying collagen-induced arthritis. Immunology 2001; 103:407-16.
    • (2001) Immunology , vol.103 , pp. 407-416
    • Luross, J.A.1    Williams, N.A.2
  • 3
    • 0029671318 scopus 로고    scopus 로고
    • Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE)
    • Ferber IA, Brocke S, Taylor-Edwards C etal. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 1996; 156:5-7.
    • (1996) J Immunol , vol.156 , pp. 5-7
    • Ferber, I.A.1    Brocke, S.2    Taylor-Edwards, C.3
  • 4
    • 0030587910 scopus 로고    scopus 로고
    • IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • Willenborg DO, Fordham S, Bernard CC, Cowden WB, Ramshaw IA. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 1996; 157:3223-7.
    • (1996) J Immunol , vol.157 , pp. 3223-3227
    • Willenborg, D.O.1    Fordham, S.2    Bernard, C.C.3    Cowden, W.B.4    Ramshaw, I.A.5
  • 6
    • 0037434789 scopus 로고    scopus 로고
    • Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
    • Cua DJ, Sherlock J, Chen Y etal. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003; 421:744-8.
    • (2003) Nature , vol.421 , pp. 744-748
    • Cua, D.J.1    Sherlock, J.2    Chen, Y.3
  • 7
    • 0346962972 scopus 로고    scopus 로고
    • Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
    • Murphy CA, Langrish CL, Chen Y etal. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 2003; 198:1951-7.
    • (2003) J Exp Med , vol.198 , pp. 1951-1957
    • Murphy, C.A.1    Langrish, C.L.2    Chen, Y.3
  • 8
    • 0344585384 scopus 로고    scopus 로고
    • Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice
    • Nakae S, Nambu A, Sudo K, Iwakura Y. Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice. J Immunol 2003; 171:6173-7.
    • (2003) J Immunol , vol.171 , pp. 6173-6177
    • Nakae, S.1    Nambu, A.2    Sudo, K.3    Iwakura, Y.4
  • 9
    • 33745321276 scopus 로고    scopus 로고
    • IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
    • Komiyama Y, Nakae S, Matsuki T etal. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J Immunol 2006; 177:566-73.
    • (2006) J Immunol , vol.177 , pp. 566-573
    • Komiyama, Y.1    Nakae, S.2    Matsuki, T.3
  • 10
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Harrington LE, Hatton RD, Mangan PR etal. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 2005; 6:1123-32.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3
  • 11
    • 34247247352 scopus 로고    scopus 로고
    • Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17
    • Chu CQ, Swart D, Alcorn D, Tocker J, Elkon KB. Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17. Arthritis Rheum 2007; 56:1145-51.
    • (2007) Arthritis Rheum , vol.56 , pp. 1145-1151
    • Chu, C.Q.1    Swart, D.2    Alcorn, D.3    Tocker, J.4    Elkon, K.B.5
  • 12
    • 0034600788 scopus 로고    scopus 로고
    • Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells
    • Dalton DK, Haynes L, Chu CQ, Swain SL, Wittmer S. Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J Exp Med 2000; 192:117-22.
    • (2000) J Exp Med , vol.192 , pp. 117-122
    • Dalton, D.K.1    Haynes, L.2    Chu, C.Q.3    Swain, S.L.4    Wittmer, S.5
  • 13
    • 0034601012 scopus 로고    scopus 로고
    • Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis
    • Chu CQ, Wittmer S, Dalton DK. Failure to suppress the expansion of the activated CD4 T cell population in interferon gamma-deficient mice leads to exacerbation of experimental autoimmune encephalomyelitis. J Exp Med 2000; 192:123-8.
    • (2000) J Exp Med , vol.192 , pp. 123-128
    • Chu, C.Q.1    Wittmer, S.2    Dalton, D.K.3
  • 14
    • 33748294322 scopus 로고    scopus 로고
    • Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs
    • Wang Z, Hong J, Sun W etal. Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs. J Clin Invest 2006; 116:2434-41.
    • (2006) J Clin Invest , vol.116 , pp. 2434-2441
    • Wang, Z.1    Hong, J.2    Sun, W.3
  • 15
    • 0036676974 scopus 로고    scopus 로고
    • The unconventional lifestyle of NK T cells
    • Kronenberg M, Gapin L. The unconventional lifestyle of NK T cells. Nat Rev Immunol 2002; 2:557-68.
    • (2002) Nat Rev Immunol , vol.2 , pp. 557-568
    • Kronenberg, M.1    Gapin, L.2
  • 16
    • 11244304412 scopus 로고    scopus 로고
    • alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles
    • Van Kaer L. alpha-Galactosylceramide therapy for autoimmune diseases: prospects and obstacles. Nat Rev Immunol 2005; 5:31-42.
    • (2005) Nat Rev Immunol , vol.5 , pp. 31-42
    • Van Kaer, L.1
  • 17
    • 0029121325 scopus 로고
    • Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis
    • Sumida T, Sakamoto A, Murata H etal. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis. J Exp Med 1995; 182:1163-8.
    • (1995) J Exp Med , vol.182 , pp. 1163-1168
    • Sumida, T.1    Sakamoto, A.2    Murata, H.3
  • 18
    • 0031742974 scopus 로고    scopus 로고
    • TCRAV24 gene expression in double negative T cells in systemic lupus erythematosus
    • Sumida T, Maeda T, Taniguchi M, Nishioka K, Stohl W. TCRAV24 gene expression in double negative T cells in systemic lupus erythematosus. Lupus 1998; 7:565-8.
    • (1998) Lupus , vol.7 , pp. 565-568
    • Sumida, T.1    Maeda, T.2    Taniguchi, M.3    Nishioka, K.4    Stohl, W.5
  • 20
    • 0035025559 scopus 로고    scopus 로고
    • Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases
    • Kojo S, Adachi Y, Keino H, Taniguchi M, Sumida T. Dysfunction of T cell receptor AV24AJ18+, BV11+ double-negative regulatory natural killer T cells in autoimmune diseases. Arthritis Rheum 2001; 44:1127-38.
    • (2001) Arthritis Rheum , vol.44 , pp. 1127-1138
    • Kojo, S.1    Adachi, Y.2    Keino, H.3    Taniguchi, M.4    Sumida, T.5
  • 21
    • 0034786013 scopus 로고    scopus 로고
    • The natural killer T-cell ligand a-galactosylceramide prevents autoimmune diabetes in NOD mice
    • Hong S, Wilson MT, Serizawa I etal. The natural killer T-cell ligand a-galactosylceramide prevents autoimmune diabetes in NOD mice. Nat Med 2001; 7:1052-6.
    • (2001) Nat Med , vol.7 , pp. 1052-1056
    • Hong, S.1    Wilson, M.T.2    Serizawa, I.3
  • 22
    • 0035905471 scopus 로고    scopus 로고
    • Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis
    • Singh AK, Wilson MT, Hong S etal. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J Exp Med 2001; 194:1801-11.
    • (2001) J Exp Med , vol.194 , pp. 1801-1811
    • Singh, A.K.1    Wilson, M.T.2    Hong, S.3
  • 23
    • 0043136663 scopus 로고    scopus 로고
    • Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis
    • Yang JQ, Singh AK, Wilson MT etal. Immunoregulatory role of CD1d in the hydrocarbon oil-induced model of lupus nephritis. J Immunol 2003; 171:2142-53.
    • (2003) J Immunol , vol.171 , pp. 2142-2153
    • Yang, J.Q.1    Singh, A.K.2    Wilson, M.T.3
  • 24
    • 20744454301 scopus 로고    scopus 로고
    • The involvement of Vα14 natural killer T cells in the pathogenesis of arthritis in murine models
    • Chiba A, Kaieda S, Oki S, Yamamura T, Miyake S. The involvement of Vα14 natural killer T cells in the pathogenesis of arthritis in murine models. Arthritis Rheum 2005; 52:1941-8.
    • (2005) Arthritis Rheum , vol.52 , pp. 1941-1948
    • Chiba, A.1    Kaieda, S.2    Oki, S.3    Yamamura, T.4    Miyake, S.5
  • 25
    • 21344439546 scopus 로고    scopus 로고
    • TCR Valpha14 natural killer T cells function as effector T cells in mice with collagen-induced arthritis
    • Ohnishi Y, Tsutsumi A, Goto D etal. TCR Valpha14 natural killer T cells function as effector T cells in mice with collagen-induced arthritis. Clin Exp Immunol 2005; 141:47-53.
    • (2005) Clin Exp Immunol , vol.141 , pp. 47-53
    • Ohnishi, Y.1    Tsutsumi, A.2    Goto, D.3
  • 26
    • 53049086275 scopus 로고    scopus 로고
    • Invariant NK T cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis
    • Yoshiga Y, Goto D, Segawa S etal. Invariant NK T cells produce IL-17 through IL-23-dependent and -independent pathways with potential modulation of Th17 response in collagen-induced arthritis. Int J Mol Med 2008; 22:369-74.
    • (2008) Int J Mol Med , vol.22 , pp. 369-374
    • Yoshiga, Y.1    Goto, D.2    Segawa, S.3
  • 27
    • 12344307565 scopus 로고    scopus 로고
    • NK T cells promote antibody-induced joint inflammation by suppressing transforming growth factor β1 production
    • Kim HY, Kim HJ, Min HS etal. NK T cells promote antibody-induced joint inflammation by suppressing transforming growth factor β1 production. J Exp Med 2005; 201:41-7.
    • (2005) J Exp Med , vol.201 , pp. 41-47
    • Kim, H.Y.1    Kim, H.J.2    Min, H.S.3
  • 28
    • 33748296238 scopus 로고    scopus 로고
    • FcgammaRIII engagement provides activating signals to NK T cells in antibody-induced joint inflammation
    • Kim HY, Kim S, Chung DH. FcgammaRIII engagement provides activating signals to NK T cells in antibody-induced joint inflammation. J Clin Invest 2006; 116:2484-92.
    • (2006) J Clin Invest , vol.116 , pp. 2484-2492
    • Kim, H.Y.1    Kim, S.2    Chung, D.H.3
  • 29
    • 45449103839 scopus 로고    scopus 로고
    • CD1d-restricted iNK T cells, the 'Swiss-Army knife' of the immune system
    • [Review]
    • Matsuda JL, Mallevaey T, Scott-Browne J, Gapin L. CD1d-restricted iNK T cells, the 'Swiss-Army knife' of the immune system [Review]. Curr Opin Immunol 2008; 20:358-68.
    • (2008) Curr Opin Immunol , vol.20 , pp. 358-368
    • Matsuda, J.L.1    Mallevaey, T.2    Scott-Browne, J.3    Gapin, L.4
  • 30
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001; 413:531-4.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 31
    • 0345167831 scopus 로고    scopus 로고
    • Superior protection against malaria and melanoma metastases by a C-glycoside analog of the natural killer T cell ligand alpha-galactosylceramide
    • Schmieg J, Yang G, Franck RW, Tsuji M. Superior protection against malaria and melanoma metastases by a C-glycoside analog of the natural killer T cell ligand alpha-galactosylceramide. J Exp Med 2003; 198:1631-41.
    • (2003) J Exp Med , vol.198 , pp. 1631-1641
    • Schmieg, J.1    Yang, G.2    Franck, R.W.3    Tsuji, M.4
  • 32
    • 77954045916 scopus 로고    scopus 로고
    • Induction of Th1-biased cytokine production by alpha-carba-GalCer, a neoglycolipid ligand for NK T cells
    • Tashiro T, Sekine-Kondo E, Shigeura T etal. Induction of Th1-biased cytokine production by alpha-carba-GalCer, a neoglycolipid ligand for NK T cells. Int Immunol 2010; 22:319-28.
    • (2010) Int Immunol , vol.22 , pp. 319-328
    • Tashiro, T.1    Sekine-Kondo, E.2    Shigeura, T.3
  • 33
    • 46949100430 scopus 로고    scopus 로고
    • Activation-induced NK T cell hyporesponsiveness protects from alpha-galactosylceramide hepatitis and is independent of active transregulatory factors
    • Biburger M, Tiegs G. Activation-induced NK T cell hyporesponsiveness protects from alpha-galactosylceramide hepatitis and is independent of active transregulatory factors. J Leukoc Biol 2008; 84:264-79.
    • (2008) J Leukoc Biol , vol.84 , pp. 264-279
    • Biburger, M.1    Tiegs, G.2
  • 34
    • 35548929833 scopus 로고    scopus 로고
    • Type II collagen autoimmunity in a mouse model of human rheumatoid arthritis
    • Cho YG, Cho ML, Min SY, Kim HY. Type II collagen autoimmunity in a mouse model of human rheumatoid arthritis. Autoimmun Rev 2007; 7:65-70.
    • (2007) Autoimmun Rev , vol.7 , pp. 65-70
    • Cho, Y.G.1    Cho, M.L.2    Min, S.Y.3    Kim, H.Y.4
  • 35
    • 1042280962 scopus 로고    scopus 로고
    • Down-regulation of the invariant Valpha14 antigen receptor in NK T cells upon activation
    • Harada M, Seino K, Wakao H etal. Down-regulation of the invariant Valpha14 antigen receptor in NK T cells upon activation. Int Immunol 2004; 16:241-7.
    • (2004) Int Immunol , vol.16 , pp. 241-247
    • Harada, M.1    Seino, K.2    Wakao, H.3
  • 36
    • 68149164473 scopus 로고    scopus 로고
    • Skin and peripheral lymph node invariant NK T cells are mainly retinoic acid receptor-related orphan receptor (gamma)t+ and respond preferentially under inflammatory conditions
    • Doisne JM, Becourt C, Amniai L etal. Skin and peripheral lymph node invariant NK T cells are mainly retinoic acid receptor-related orphan receptor (gamma)t+ and respond preferentially under inflammatory conditions. J Immunol 2009; 183:2142-9.
    • (2009) J Immunol , vol.183 , pp. 2142-2149
    • Doisne, J.M.1    Becourt, C.2    Amniai, L.3
  • 37
    • 0030586560 scopus 로고    scopus 로고
    • A direct role for IFN- in regulation of Th1 cell development
    • Bradley LM, Dalton DK, Croft M. A direct role for IFN- in regulation of Th1 cell development. J Immunol 1996; 157:1350-8.
    • (1996) J Immunol , vol.157 , pp. 1350-1358
    • Bradley, L.M.1    Dalton, D.K.2    Croft, M.3
  • 38
    • 0034535655 scopus 로고    scopus 로고
    • Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NK T cells and antigen-presenting cells
    • Yang YF, Tomura M, Ono S, Hamaoka T, Fujiwara H. Requirement for IFN-gamma in IL-12 production induced by collaboration between v(alpha)14(+) NK T cells and antigen-presenting cells. Int Immunol 2000; 12:1669-75.
    • (2000) Int Immunol , vol.12 , pp. 1669-1675
    • Yang, Y.F.1    Tomura, M.2    Ono, S.3    Hamaoka, T.4    Fujiwara, H.5
  • 39
    • 77952784918 scopus 로고    scopus 로고
    • Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis
    • Sheikh SZ, Matsuoka K, Kobayashi T, Li F, Rubinas T, Plevy SE. Cutting edge: IFN-gamma is a negative regulator of IL-23 in murine macrophages and experimental colitis. J Immunol 2010; 184:4069-73.
    • (2010) J Immunol , vol.184 , pp. 4069-4073
    • Sheikh, S.Z.1    Matsuoka, K.2    Kobayashi, T.3    Li, F.4    Rubinas, T.5    Plevy, S.E.6
  • 40
    • 0034667937 scopus 로고    scopus 로고
    • Selective bystander proliferation of memory CD4+ and CD8+ T cells upon NK T or T cell activation
    • Eberl G, Brawand P, MacDonald HR. Selective bystander proliferation of memory CD4+ and CD8+ T cells upon NK T or T cell activation. J Immunol 2000; 165:4305-1.
    • (2000) J Immunol , vol.165 , pp. 4305-4301
    • Eberl, G.1    Brawand, P.2    MacDonald, H.R.3
  • 41
    • 0023949959 scopus 로고    scopus 로고
    • Type II collagen-induced murine arthritis: induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity
    • Seki N, Sudo Y, Yoshioka T etal. Type II collagen-induced murine arthritis: induction and perpetuation of arthritis require synergy between humoral and cell-mediated immunity. J Immunol 1998; 140:1477-84.
    • (1998) J Immunol , vol.140 , pp. 1477-1484
    • Seki, N.1    Sudo, Y.2    Yoshioka, T.3
  • 42
    • 0022295359 scopus 로고
    • Genetic susceptibility to murine collagen II autoimmune arthritis: proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC), and non-MHC loci
    • Watson WC, Townes AS. Genetic susceptibility to murine collagen II autoimmune arthritis: proposed relationship to the IgG2 autoantibody subclass response, complement C5, major histocompatibility complex (MHC), and non-MHC loci. J Exp Med 1985; 162:1878-91.
    • (1985) J Exp Med , vol.162 , pp. 1878-1891
    • Watson, W.C.1    Townes, A.S.2
  • 43
    • 0025838109 scopus 로고
    • IgE class switching is critically dependent upon the nature of the B cell activator, in addition to the presence of IL-4
    • Snapper CM, Peçanha LM, Levine AD, Mond JJ. IgE class switching is critically dependent upon the nature of the B cell activator, in addition to the presence of IL-4. J Immunol 1991; 147:1163-70.
    • (1991) J Immunol , vol.147 , pp. 1163-1170
    • Snapper, C.M.1    Peçanha, L.M.2    Levine, A.D.3    Mond, J.J.4
  • 44
    • 0025811173 scopus 로고
    • IFN- enhances secretion of IgG2a from IgG2a-committed LPS-stimulated murine B cells: implications for the role of IFN- in class switching
    • Bossie A, Vitetta ES. IFN- enhances secretion of IgG2a from IgG2a-committed LPS-stimulated murine B cells: implications for the role of IFN- in class switching. Cell Immunol 1991; 135:95-104.
    • (1991) Cell Immunol , vol.135 , pp. 95-104
    • Bossie, A.1    Vitetta, E.S.2
  • 45
    • 67649197343 scopus 로고    scopus 로고
    • Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus
    • Doreau A, Belot A, Bastid J etal. Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus. Nat Immunol 2009; 10:778-85.
    • (2009) Nat Immunol , vol.10 , pp. 778-785
    • Doreau, A.1    Belot, A.2    Bastid, J.3
  • 47
    • 0028848472 scopus 로고
    • Role of interferon-gamma in immune cell regulation
    • Young HA, Hardy KJ. Role of interferon-gamma in immune cell regulation. J Leukoc Biol 1995; 58:373.
    • (1995) J Leukoc Biol , vol.58 , pp. 373
    • Young, H.A.1    Hardy, K.J.2
  • 48
    • 29744438008 scopus 로고    scopus 로고
    • Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway
    • Miellot A, Zhu R, Diem S, Boissier MC, Herbelin A, Bessis N. Activation of invariant NK T cells protects against experimental rheumatoid arthritis by an IL-10-dependent pathway. Eur J Immunol 2005; 35:3704-13.
    • (2005) Eur J Immunol , vol.35 , pp. 3704-3713
    • Miellot, A.1    Zhu, R.2    Diem, S.3    Boissier, M.C.4    Herbelin, A.5    Bessis, N.6
  • 49
    • 34848863949 scopus 로고    scopus 로고
    • A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner
    • Coppieters K, Van Beneden K, Jacques P etal. A single early activation of invariant NK T cells confers long-term protection against collagen-induced arthritis in a ligand-specific manner. J Immunol 2007; 179:2300-9.
    • (2007) J Immunol , vol.179 , pp. 2300-2309
    • Coppieters, K.1    Van Beneden, K.2    Jacques, P.3
  • 50
    • 10744230210 scopus 로고    scopus 로고
    • NK T cells enhance CD4+ and CD8+ T-cell responses to soluble antigen in vivo through direct interaction with dendritic cells
    • Hermans IF, Silk JD, Gileadi U etal. NK T cells enhance CD4+ and CD8+ T-cell responses to soluble antigen in vivo through direct interaction with dendritic cells. J Immunol 2003; 171:5140-7.
    • (2003) J Immunol , vol.171 , pp. 5140-5147
    • Hermans, I.F.1    Silk, J.D.2    Gileadi, U.3


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