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Volumn 4, Issue 3, 2011, Pages 477-481

Effect of glucopyranosylidene-spiro-thiohydantoin on glycogen metabolism in liver tissues of streptozotocin-induced and obese diabetic rats

Author keywords

Glucose analogue inhibitors; Glycogen phosphorylase; Glycogen synthase; Zucker diabetic fatty rat

Indexed keywords

ANTIDIABETIC AGENT; GLUCOPYRANOSYLIDENE SPIRO THIOHYDANTOIN; GLUCOSE; GLYCOGEN; GLYCOGEN PHOSPHORYLASE; GLYCOGEN PHOSPHORYLASE ALPHA; GLYCOGEN SYNTHASE; LIVER EXTRACT; STREPTOZOCIN; THIOHYDANTOIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 79953782814     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2011.464     Document Type: Article
Times cited : (52)

References (37)
  • 1
    • 67651239262 scopus 로고    scopus 로고
    • Enhancing insulin action with physical activity to prevent and control diabetes
    • Colberg SE: Enhancing insulin action with physical activity to prevent and control diabetes. ACSM'S Health and Fitness Journal 12: 16-22, 2008.
    • (2008) ACSM'S Health and Fitness Journal , vol.12 , pp. 16-22
    • Colberg, S.E.1
  • 2
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • DOI 10.1038/414782a
    • Zimmet P, Alberti KG and Shaw J: Global and societal implications of the diabetes epidemic. Nature 414: 782-787, 2001. (Pubitemid 34000780)
    • (2001) Nature , vol.414 , Issue.6865 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.M.M.2    Shaw, J.3
  • 3
    • 63249113539 scopus 로고    scopus 로고
    • Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens
    • Sai Yd, Marrero IG, Gros P, Zaghouani H, Wicker LS and Sercarz EE: Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. Diabetes 58: 156-164, 2009.
    • (2009) Diabetes , vol.58 , pp. 156-164
    • Sai, Y.D.1    Marrero, I.G.2    Gros, P.3    Zaghouani, H.4    Wicker, L.S.5    Sercarz, E.E.6
  • 5
    • 0141566770 scopus 로고    scopus 로고
    • Hepatic glucose metabolism in humans - Its role in health and disease
    • Roden M and Bernroider E: Hepatic glucose metabolism in humans - its role in health and disease. Best Pract Res Clin Endocrinol Metab 17: 365-383, 2003.
    • (2003) Best Pract Res Clin Endocrinol Metab , vol.17 , pp. 365-383
    • Roden, M.1    Bernroider, E.2
  • 6
    • 77954530704 scopus 로고    scopus 로고
    • Molecular mechanism of insulin resistance in obesity and type 2 diabetes
    • Choi K and Kim YB: Molecular mechanism of insulin resistance in obesity and type 2 diabetes. Korean J Intern Med 25: 119-129, 2010.
    • (2010) Korean J Intern Med , vol.25 , pp. 119-129
    • Choi, K.1    Kim, Y.B.2
  • 7
    • 0028961526 scopus 로고
    • Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration
    • Magnusson I, Rothman DL, Gerard DP, Katz LD and Shulman GI: Contribution of hepatic glycogenolysis to glucose production in humans in response to a physiological increase in plasma glucagon concentration. Diabetes 44: 185-189, 1995.
    • (1995) Diabetes , vol.44 , pp. 185-189
    • Magnusson, I.1    Rothman, D.L.2    Gerard, D.P.3    Katz, L.D.4    Shulman, G.I.5
  • 8
    • 0031952156 scopus 로고    scopus 로고
    • Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM
    • Diraison F, Large V, Brunengraber H and Beylot M: Non-invasive tracing of liver intermediary metabolism in normal subjects and in moderately hyperglycaemic NIDDM subjects. Evidence against increased gluconeogenesis and hepatic fatty acid oxidation in NIDDM. Diabetologia 41: 212-220, 1998.
    • (1998) Diabetologia , vol.41 , pp. 212-220
    • Diraison, F.1    Large, V.2    Brunengraber, H.3    Beylot, M.4
  • 9
    • 0033567989 scopus 로고    scopus 로고
    • Inhibition of glycogenolysis in primary rat hepatocytes by 1,4-dideoxy-1,4-imino-D-arabinitol
    • DOI 10.1042/0264-6021:3420545
    • Andersen B, Rassov A, Westergaard N and Lundgren K: Inhibition of glycogenolysis in primary rat hepatocytes by 1, 4-dideoxy-1,4-imino-d- arabinitol. Biochem J 342 (Pt 3): 545-550, 1999. (Pubitemid 29452639)
    • (1999) Biochemical Journal , vol.342 , Issue.3 , pp. 545-550
    • Andersen, B.1    Rassov, A.2    Westergaard, N.3    Lundgren, K.4
  • 10
    • 0035110957 scopus 로고    scopus 로고
    • Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus
    • DOI 10.1517/13543784.10.3.439
    • Treadway JL, Mendys P and Hoover DJ: Glycogen phosphorylase inhibitors for treatment of type 2 diabetes mellitus. Expert Opin Investig Drugs 10: 439-454, 2001. (Pubitemid 32186142)
    • (2001) Expert Opinion on Investigational Drugs , vol.10 , Issue.3 , pp. 439-454
    • Treadway, J.L.1    Mendys, P.2    Hoover, D.J.3
  • 11
    • 0037648878 scopus 로고    scopus 로고
    • Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: Recent developments
    • DOI 10.2174/1381612033454919
    • Somsak L, Nagya V, Hadady Z, Docsa T and Gergely P: Glucose analog inhibitors of glycogen phosphorylases as potential antidiabetic agents: recent developments. Curr Pharm Des 9: 1177-1189, 2003. (Pubitemid 36582253)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.15 , pp. 1177-1189
    • Somsak, L.1    Nagy, V.2    Hadady, Z.3    Docsa, T.4    Gergely, P.5
  • 12
    • 24644516232 scopus 로고    scopus 로고
    • Synthesis of some derivatives of C-(1-deoxy-1-N-substituted-d- Glucopyranosyl)formic acid (D-gluco-hept-2-ulopyranosonic acid) as potential inhibitors of glycogen phosphorylase
    • DOI 10.1016/j.carres.2005.06.033, PII S0008621505003605
    • Czifrak K, Kovacs L, Kover KE and Somsak L: Synthesis of some derivatives of C-(1-deoxy-1-N-substituted-D-glucopyranosyl) formic acid (D-gluco-hept-2-ulopyranosonic acid) as potential inhibitors of glycogen phosphorylase. Carbohydr Res 340: 2328-2334, 2005. (Pubitemid 41268657)
    • (2005) Carbohydrate Research , vol.340 , Issue.14 , pp. 2328-2334
    • Czifrak, K.1    Kovacs, L.2    Kover, K.E.3    Somsak, L.4
  • 13
    • 58149402805 scopus 로고    scopus 로고
    • New inhibitors of glycogen phosphorylase as potential antidiabetic agents
    • Somsak L, Czifrak K, Toth M, et al: New inhibitors of glycogen phosphorylase as potential antidiabetic agents. Curr Med Chem 15: 2933-2983, 2008.
    • (2008) Curr Med Chem , vol.15 , pp. 2933-2983
    • Somsak, L.1    Czifrak, K.2    Toth, M.3
  • 15
    • 78549257789 scopus 로고    scopus 로고
    • Physiological control of liver glycogen metabolism: Lessons from novel glycogen phosphorylase inhibitors
    • Agius L: Physiological control of liver glycogen metabolism: lessons from novel glycogen phosphorylase inhibitors. Mini Rev Med Chem 10: 1175-1187, 2010.
    • (2010) Mini Rev Med Chem , vol.10 , pp. 1175-1187
    • Agius, L.1
  • 18
    • 0021960278 scopus 로고
    • 2from rabbit skeletal muscle
    • DOI 10.1111/j.1432-1033.1985.tb08833.x
    • Tung HY, Alemany S and Cohen P: The protein phosphatases involved in cellular regulation. 2. Purification, subunit structure and properties of protein phosphatases-2A0, 2A1, and 2A2 from rabbit skeletal muscle. Eur J Biochem 148: 253-263, 1985. (Pubitemid 15093611)
    • (1985) European Journal of Biochemistry , vol.148 , Issue.2 , pp. 253-263
    • Tung, H.Y.L.1    Alemany, S.2    Cohen, P.3
  • 19
    • 0035899177 scopus 로고    scopus 로고
    • Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-gluco- and D-xylopyranosylidene-spiro-(thio)hydantoins and N-(D-glucopyranosyl) amides
    • DOI 10.1021/jm010892t
    • Somsak L, Kovacs L, Toth M, et al: Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of d-gluco- and d-xylopyranosylidene-spiro-(thio)hydantoins and N-(d-glucopyranosyl) amides. J Med Chem 44: 2843-2848, 2001. (Pubitemid 32879725)
    • (2001) Journal of Medicinal Chemistry , vol.44 , Issue.17 , pp. 2843-2848
    • Somsak, L.1    Kovacs, L.2    Toth, M.3    Osz, E.4    Szilagyi, L.5    Gyorgydeak, Z.6    Dinya, Z.7    Docsa, T.8    Toth, B.9    Gergely, P.10
  • 20
    • 0035691617 scopus 로고    scopus 로고
    • The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas
    • Szkudelski T: The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas. Physiol Res 50: 537-546, 2001.
    • (2001) Physiol Res , vol.50 , pp. 537-546
    • Szkudelski, T.1
  • 21
    • 0035149733 scopus 로고    scopus 로고
    • A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat
    • Griffen SC, Wang J and German MS: a genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat. Diabetes 50: 63-68, 2001. (Pubitemid 32047982)
    • (2001) Diabetes , vol.50 , Issue.1 , pp. 63-68
    • Griffen, S.C.1    Wang, J.2    German, M.S.3
  • 22
    • 78549295877 scopus 로고    scopus 로고
    • Inhibition of glycogen phosphorylase in the context of type 2 diabetes, with focus on recent inhibitors bound at the active site
    • Praly JP and Vidal S: Inhibition of glycogen phosphorylase in the context of type 2 diabetes, with focus on recent inhibitors bound at the active site. Mini Rev Med Chem 10: 1102-1126, 2010.
    • (2010) Mini Rev Med Chem , vol.10 , pp. 1102-1126
    • Praly, J.P.1    Vidal, S.2
  • 23
    • 0028955885 scopus 로고
    • Potent inhibition of glycogen-phosphorylase by a spirohydantoin of glucopyranose - First pyranose analogs of hydantocidin
    • Bichard CJF, Mitchell EP, Wormald MR, et al: Potent inhibition of glycogen-phosphorylase by a spirohydantoin of glucopyranose - first pyranose analogs of hydantocidin. Tetrahedron Letters 36: 2145-2148, 1995.
    • (1995) Tetrahedron Letters , vol.36 , pp. 2145-2148
    • Bichard, C.J.F.1    Mitchell, E.P.2    Wormald, M.R.3
  • 24
    • 0033577776 scopus 로고    scopus 로고
    • Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin
    • DOI 10.1016/S0960-894X(99)00192-4, PII S0960894X99001924
    • Osz E, Somsak L, Szilagyi L, et al: Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin. Bioorg Med Chem Lett 9: 1385-1390, 1999. (Pubitemid 29232212)
    • (1999) Bioorganic and Medicinal Chemistry Letters , vol.9 , Issue.10 , pp. 1385-1390
    • Osz, E.1    Somsak, L.2    Szilagyi, L.3    Kovacs, L.4    Docsa, T.5    Toth, B.6    Gergely, P.7
  • 25
    • 0034635613 scopus 로고    scopus 로고
    • Gram-scale synthesis of a glucopyranosylidene-spiro-thiohydantoin and its effect on hepatic glycogen metabolism studied in vitro and in vivo
    • DOI 10.1016/S0957-4166(99)00486-3, PII S0957416699004863
    • Somsak L, Nagy V, Docsa T, Toth B and Gergely P: Gram-scale synthesis of a glucopyranosylidene-spiro-thiohydantoin and its effect on hepatic glycogen metabolism studied in vitro and in vivo. Tetrahedron-Asymmetry 11: 405-408, 2000. (Pubitemid 30125484)
    • (2000) Tetrahedron Asymmetry , vol.11 , Issue.2 , pp. 405-408
    • Somsak, L.A.1    Nagy, V.2    Docsa, T.3    Toth, B.E.4    Gergely, P.A.5
  • 26
    • 0034607764 scopus 로고    scopus 로고
    • A new, scalable preparation of a glucopyranosylidene-spiro- Thiohydantoin: One of the best inhibitors of glycogen phosphorylases
    • DOI 10.1016/S0957-4166(00)00107-5, PII S0957416600001075
    • Somsak L and Nagy V: A new, scalable preparation of a glucopyranosylidene-spiro-thiohydantoin: one of the best inhibitors of glycogen phosphorylases. Tetrahedron Asymmetry 11: 1719-1727, 2000. (Pubitemid 30320893)
    • (2000) Tetrahedron Asymmetry , vol.11 , Issue.8 , pp. 1719-1727
    • Somsak, L.A.1    Nagy, V.2
  • 27
    • 0022540472 scopus 로고
    • Hormonal regulation of phosphorylase phosphatase activity in rat liver
    • DOI 10.1016/0014-5793(86)80753-0
    • Farkas I, Toth B, Bot G and Gergely P: Hormonal regulation of phosphorylase phosphatase activity in rat liver. FEBS Lett 203: 253-256, 1986. (Pubitemid 16046806)
    • (1986) FEBS Letters , vol.203 , Issue.2 , pp. 253-256
    • Farkas, I.1    Toth, B.2    Bot, G.3    Gergely, P.4
  • 28
    • 0019072027 scopus 로고
    • Cyclic AMP- and Ca2+-independent glycogen synthase kinase from dog liver
    • Dopere F, Goris J, Vandenheede Jr and Merlevede W: Cyclic AMP- and Ca2+-independent glycogen synthase kinase from dog liver. Biochem Soc Trans 8: 526-527, 1980.
    • (1980) Biochem Soc Trans , vol.8 , pp. 526-527
    • Dopere, F.1    Vandenheede Jr., G.J.2    Merlevede, W.3
  • 29
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 30
    • 0014738371 scopus 로고
    • Determination of glycogen in small tissue samples
    • Lo S, Russell JC and Taylor AW: Determination of glycogen in small tissue samples. J Appl Physiol 28: 234-236, 1970.
    • (1970) J Appl Physiol , vol.28 , pp. 234-236
    • Lo, S.1    Russell, J.C.2    Taylor, A.W.3
  • 31
    • 0023138702 scopus 로고
    • Control of glycogen synthesis in health and disease
    • Stalmans W, Bollen M and Mvumbi L: Control of glycogen synthesis in health and disease. Diabetes Metab Rev 3: 127-161, 1987. (Pubitemid 17002811)
    • (1987) Diabetes/Metabolism Reviews , vol.3 , Issue.1 , pp. 127-161
    • Stalmans, W.1    Bollen, M.2    Mvumbi, L.3
  • 34
    • 0017667461 scopus 로고
    • The effect of streptozotocin induced diabetes and of insulin supplementation on glycogen metabolism in rat liver
    • Khandelwal RL, Zinman SM and Zebrowski EJ: The effect of streptozotocin-induced diabetes and of insulin supplementation on glycogen metabolism in rat liver. Biochem J 168: 541-548, 1977. (Pubitemid 8246943)
    • (1977) Biochemical Journal , vol.168 , Issue.3 , pp. 541-548
    • Khandelwal, R.L.1    Zinman, S.M.2    Zebrowski, E.J.3
  • 35
    • 25144503390 scopus 로고    scopus 로고
    • FR258900, a novel glycogen phosphorylase inhibitor isolated from Fungus No. 138354. II. Anti-hyperglycemic effects in diabetic animal models
    • Furukawa S, Murakami K, Nishikawa M, Nakayama O and Hino M: FR258900, a novel glycogen phosphorylase inhibitor isolated from Fungus No. 138354. II. Anti-hyperglycemic effects in diabetic animal models. J Antibiot 58: 503-506, 2005.
    • (2005) J Antibiot , vol.58 , pp. 503-506
    • Furukawa, S.1    Murakami, K.2    Nishikawa, M.3    Nakayama, O.4    Hino, M.5
  • 36
    • 78549249174 scopus 로고    scopus 로고
    • Synthesis of N-glucopyranosidic derivatives as potential inhibitors that bind at the catalytic site of glycogen phosphorylase
    • Gimisis T: Synthesis of N-glucopyranosidic derivatives as potential inhibitors that bind at the catalytic site of glycogen phosphorylase. Mini Rev Med Chem 10: 1127-1138, 2010.
    • (2010) Mini Rev Med Chem , vol.10 , pp. 1127-1138
    • Gimisis, T.1
  • 37
    • 78549267168 scopus 로고    scopus 로고
    • Recent advances in the allosteric inhibition of glycogen phosphorylase
    • Loughlin WA: Recent advances in the allosteric inhibition of glycogen phosphorylase. Mini Rev Med Chem 10: 1139-1155, 2010.
    • (2010) Mini Rev Med Chem , vol.10 , pp. 1139-1155
    • Loughlin, W.A.1


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