Shedding new light on ZnCl2-mediated addition reactions of Grignard reagents to ketones: Structural authentication of key intermediates and diffusion-ordered NMR studies

Chemistry - A European Journal

Volumn 17, Issue 16, 2011, Pages 4470-4479

  Armstrong, David R ^a   Clegg, William ^b   García Alvarez, Pablo ^c   McCall, Matthew D ^a   Nuttall, Lorraine ^a   Kennedy, Alan R ^a   Russo, Luca ^b   Hevia, Eva ^a  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF OVIEDO   (Spain)

Author keywords

addition reactions; Grignard reagents; mixed metal chemistry; NMR spectroscopy; zincates

Indexed keywords

ALKOXIDE LIGANDS; ALKYLATION REACTIONS; CATALYTIC AMOUNTS; CHARACTERISATION; CHEMO-SELECTIVITY; DOSY NMR; GRIGNARD REAGENT; INORGANIC SALTS; MAGNESIATE; MAGNESIUM CHEMISTRY; METATHESIS REACTIONS; MIXED-METAL CHEMISTRY; MOLAR EQUIVALENT; NMR SPECTROSCOPY; NMR STUDIES; REDUCTION PRODUCTS; STRUCTURAL MOTIFS; STRUCTURAL SUPPORT; SYNERGIC EFFECTS; TRIFLUOROACETOPHENONE; ZINCATES;

CHLORINE; KETONES; MAGNESIUM; MINERALOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANOMETALLICS; REACTION INTERMEDIATES; SELF ASSEMBLY; SYNTHESIS (CHEMICAL); X RAY CRYSTALLOGRAPHY; X RAYS; ZINC;

ADDITION REACTIONS;

EID: 79953715957     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.201002544     Document Type: Article

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