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Volumn 14, Issue 2, 2010, Pages 339-345

Scaleable preparation of functionalized organometallics via directed ortho metalation using Mg- and Zn-amide bases

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Indexed keywords


EID: 77950113275     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op9002888     Document Type: Article
Times cited : (70)

References (50)
  • 4
  • 42
    • 77950106763 scopus 로고    scopus 로고
    • Tmp-H can be added at once to iPrMgCl · LiCl at 25 °C; a slight exothermic reaction was observed. For the preparation in 1.1 mol scale, no external cooling was necessary
    • Tmp-H can be added at once to iPrMgCl · LiCl at 25 °C; a slight exothermic reaction was observed. For the preparation in 1.1 mol scale, no external cooling was necessary.
  • 46
    • 77950118724 scopus 로고    scopus 로고
    • In a 1 mmol scale, a yield of 92% was observed (ref 4a). The order and the rate of addition of iodine are important for larger scales. Different conditions than the ones reported in the Experimental Section lead even to lower yields
    • In a 1 mmol scale, a yield of 92% was observed (ref 4a). The order and the rate of addition of iodine are important for larger scales. Different conditions than the ones reported in the Experimental Section lead even to lower yields.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.