DEM-CFD modeling of a fluidized bed spray granulator

Chemical Engineering Science

Volumn 66, Issue 11, 2011, Pages 2340-2355

  Fries, L ^a   Antonyuk, S ^a   Heinrich, S ^a   Palzer, S ^b  

^a HAMBURG UNIVERSITY OF TECHNOLOGY   (Germany)

^b NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Computational fluid dynamics (CFD); Discrete element modeling (DEM); Fluidization; Granulation; Particle formation; Wurster coater

Indexed keywords

AIR FLOW-RATE; BOTTOM PLATE; BUBBLING FLUIDIZED BED; CFD MODELING; CFD SIMULATIONS; CIRCULATING FLUIDIZATION; COLLISION BEHAVIOR; CONTACT MODELS; DISCRETE ELEMENT MODELING; FLUIDIZED BED GRANULATOR; GAP DISTANCES; INDIVIDUAL PARTICLES; JET VELOCITIES; MATERIAL PROPERTY; MATERIAL TESTS; MICROPROCESSES; MODELING TOOL; PARTICLE DYNAMICS; PARTICLE FORMATION; PARTICLE SURFACE; PROCESS PARAMETERS; RESIDENCE TIME DISTRIBUTIONS; SCALE-UP; SPRAY INJECTION; WURSTER;

COMPUTATIONAL FLUID DYNAMICS; FLUID DYNAMICS; FLUIDIZATION; FLUIDIZED BED PROCESS; FLUIDIZED BEDS; FLUIDS; GRANULATION; GRANULATORS; MATERIALS PROPERTIES; MODELS; WETTING;

PARTICLES (PARTICULATE MATTER);

EID: 79953689260     PISSN: 00092509     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ces.2011.02.038     Document Type: Article

References (44)

1. Antonyuk S., Heinrich S., Deen N., Kuipers J.A.M. Influence of liquid layers on energy absorption during particle impact. Particuology 2009, 7(4):245-259.
2. Antonyuk S., Heinrich S., Tomas J., Deen N.G., van Buijtenen M.S., Kuipers J.A.M. Energy absorption during compression and impact of dry elastic-plastic spherical granules. Granular Matter 2010, 12:15-47.
3. Antonyuk S., Palis S., Heinrich S. Breakage behaviour of agglomerates and crystals by static loading and impact. Powder Technology 2011, 206:88-98.
4. Deen N.G., Van Sint Annaland M., Van der Hoef M.A., Kuipers J.A.M. Review of discrete particle modelling of fluidized beds. Chemical Engineering Science 2007, 62:28-44.
5. Ennis B.J., Tardos G., Pfeffer R. A microlevel-based characterization of granulation phenomena. Powder Technology 1991, 65:257-272.
6. Ergun S. Fluid flow through packed columns. Chemical Engineering Progress 1952, 48:89-94.
7. Favier J. EDEM-CFD Coupling Module for FLUENT User Guide, Revision 2A 2009, DEMSolutions Ltd.
8. Ferry J.D. Visco-elastic Properties of Polymers 1980, J. Wiley & Sons, New York, USA. 3rd edition.
9. Gantt J.A., Gatzke E.P. High-shear granulation modelling using a discrete element simulation approach. Powder Technology 2005, 156:195-212.
10. Goldschmidt, M.J.V., 2001. Hydrodynamic modelling of fluidised bed spray granulation. Ph.D. Thesis, Twente University, Enschede, The Netherlands, p. 13.
11. Goldschmidt M.J.V., Kuipers J.A.M. Discrete element modelling of fluidised bed spray granulation. Powder Technology 2003, 138:39-45.
12. Gryczka O., Heinrich S., Deen N.G., Van Sint Annaland M., Kuipers J.A.M., Jacob M., Mörl L. Characterization and CFD-modelling of the hydrodynamics of a prismatic spouted bed apparatus. Chemical Engineering Science 2009, 64(14):3352-3375.
13. Heinrich S., Peglow M., Ihlow M., Mörl L. Particle population modelling in fluidized bed-spray granulation-analysis of the steady state and unsteady behaviour. Powder Technology 2003, 130(special issue):154-161.
14. Hede P.D., Bach P., Jensen A.D. Batch top-spray fluid bed coating: scale-up insight using dynamic heat- and mass-transfer modelling. Chemical Engineering Science 2009, 64:1293-1317.
15. Hemati M., Cherif F., Saleh K., Pont V. Fluidized bed coating and granulation: influence of process related variables and physicochemical properties on the growth kinetics. Powder Technology 2003, 130:18-34.
16. Hertz H. Über die Berührung fester elastischer Körper. Journal für die Reine und Angewandte Mathematik 1882, 92:156-171.
17. Hoomans B.P.B., Kuipers J.A.M., Briels W.J., Van Swaaij W.P.M. Discrete particle simulation of bubble and slug formation in a two-dimensional gas-fluidised bed: a hard-sphere approach. Chemical Engineering Science 1996, 51(1):99-118.
18. Hounslow M.J., Ryall R.L., Marshall V.R. A discretized population balance for nucleation, growth and aggregation. A.I.Ch.E. Journal 1988, 41:1821-1832.
19. Iveson S.M., Litster J.D., Hapgood K., Ennis B.J. Nucleation, growth and breakage phenomena in agitated wet granulation processes: a review. Powder Technology 2001, 117:3-39.
20. Johnson K.L., Kendall K., Roberts A.D. Surface energy and the contact of elastic solids. Proceedings of the Royal Society of London A 1971, 324:301-313.
21. Kafui D.K., Thornton C. Fully-3D DEM simulation of fluidised bed spray granulation using an exploratory surface-energy based spray zone concept. Powder Technology 2008, 184:177-188.
22. Karlsson S., Rasmuson A., van Wachem B., Niklasson Björn I. CFD modelling of the Wurster bed coater. A.I.Ch.E. Journal 2009, 55(10):2578-2590.
23. Kumar J., Peglow M., Warnecke G., Heinrich S., Mörl L. Improved accuracy and convergence of discretized population balance for aggregation: the cell average technique. Chemical Engineering Science 2006, 61:3327-3342.
24. KuShaari K., Pandey P., Song Y., Turton R. Monte Carlo simulations to determine coating uniformity in a Wurster fluidized bed coating process. Powder Technology 2006, 166:81-90.
25. Link J.M., Godlieb W., Deen N.G., Kuipers J.A.M. Discrete element study of granulation in a spout fluidized bed. Chemical Engineering Science 2007, 62:195-207.
26. Litster J.D., Smit D.J., Hounslow M.J. Adjustable discretization balance for growth and aggregation. A.I.Ch.E. Journal 1995, 41:591-603.
27. Litster J.D. Scaleup of wet granulation processes: science not art. Powder Technology 2003, 130:35-40.
28. Liu L.X., Litster J.D. Coalescence of deformable granules in wet granulation processes. A.I.Ch.E. Journal 2000, 46(3):529-539.
29. Mindlin R.D., Deresiewicz H. Elastic spheres in contact under varying oblique forces. Journal of Applied Mechanics-Transactions of the ASME, Series E 1953, 20:327-344.
30. Palzer S. Influence of material properties on the agglomeration of water-soluble amorphous particles. Powder Technology 2009, 189:318-326.
31. Patil D.J., Van Sint Annaland M., Kuipers J.A.M. Critical comparison of hydrodynamic models for gas-solid fluidized beds-Part I: bubbling gas-solid fluidized beds operated with a jet. Chemical Engineering Science 2005, 60:57-72.
32. Peglow M., Kumar J., Hampel R., Tsotsas E., Heinrich S. Towards a complete population balance model for fluidized-bed spray agglomeration. Drying Technology 2007, 25:1321-1329.
33. Rajniak P., Stepanek F., Dhanasekharan K., Fan R., Mancinelli C., Chern R.T. A combined experimental and computational study of wet granulation in a Wurster fluid bed granulator. Powder Technology 2009, 189:190-201.
34. Tan H.S., Salman A.D., Hounslow M.J. Kinetics of fluidized bed melt granulation I: the effect of process variables. Chemical Engineering Science 2006, 61:1585-1601.
35. Tang E.S.K., Wang L., Liew C.V., Chan L.W., Heng P.W.S. Drying efficiency and particle movement in coating-impact on particle agglomeration and yield. International Journal of Pharmaceutics 2008, 350:172-180.
36. Terrazas-Velarde K., Peglow M., Tsotsas E. Stochastic simulation of agglomerate formation in fluidized bed spray drying: a micro-scale approach. Chemical Engineering Science 2009, 64:2631-2643.
37. Teunou E., Poncelet D. Batch and continuous fluid bed coating-review and state of the art. Journal of Food Engineering 2002, 53:325-340.
38. Tsuji Y., Tanaka T., Ishida T. Lagrangian numerical simulation of plug flow of cohesionless particles in a horizontal pipe. Powder Technology 1992, 71:239-250.
39. Tsuji Y., Kawaguchi T., Tanaka T. Discrete particle simulation of two-dimensional fluidized bed. Powder Technology 1993, 77(1):79-87.
40. Turton R. Challenges in the modelling and prediction of coating of pharmaceutical dosage forms. Powder Technology 2008, 181:186-194.
41. van Buijtenen M., Deen N., Heinrich S., Antonyuk S., Kuipers J.A.M. A discrete element study of wet particle-particle interaction during granulation in a spout fluidized bed. Canadian Journal of Chemical Engineering 2009, 87:308-317.
42. Wen Y.C., Yu Y.H. Mechanics of fluidization. Chemical Engineering Progress Symposium Series 1966, 62:100-111.
43. Werner S.R.L., Jones J.R., Paterson A.H.J., Archer R.H., Pearce D.L. Air suspension coating in the food industry: Part II-micro-level process approach. Powder Technology 2007, 171:34-45.
44. Wurster, D.E., 1966. Particle coating process. US Patent No. 3,253,944, Wisconsin Alumni Research Foundation.