Drying efficiency and particle movement in coating-Impact on particle agglomeration and yield

International Journal of Pharmaceutics

Volumn 350, Issue 1-2, 2008, Pages 172-180

  Tang, E S K ^a   Wang, L ^a   Liew, C V ^a   Chan, L W ^a   Heng, P W S ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Agglomeration; Airflow; Coating; Drying; Swirl

Indexed keywords

AIR TEMPERATURE; AIRFLOW; ARTICLE; DRUG COATING; FLUIDIZATION; PELLET EXTRUSION; PRIORITY JOURNAL; SPRAY DRYING; THERMODYNAMICS;

PARTICLE SIZE; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE; THERMODYNAMICS;

EID: 38349173086     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.08.047     Document Type: Article

References (17)

1. Chan L.W., Tang E.S.K., and Heng P.W.S. Comparative study of the fluid dynamics of bottom spray fluid bed coaters. AAPS Pharm. Sci. Technol. 7 (2006) Article 37
2. Cole G.C. Introduction and overview of pharmaceutical coating. In: Cole G.C. (Ed). Pharmaceutical Coating Technology (1995), Taylor & Francis, London 1-5
3. Dechesne J.P., and Delattre L. A new enteric tablet of acetylsalicylic acid. II. Biopharmaceutical aspects. Int. J. Pharm. 34 (1986) 259-262
4. Hemati M., Cherif R., Saleh K., and Pont V. Fluidized bed coating and granulation: influence of process-related variables and physicochemical properties on the growth kinetics. Powder Technol. 130 (2003) 18-34
5. Heng P.W.S., Chan L.W., and Tang E.S.K. Use of swirling airflow to enhance coating performance of bottom spray fluid bed coaters. Int. J. Pharm. 327 (2006) 26-35
6. Johansson B., Nicklasson F., and Alderborn G. Effect of pellet size on degree of deformation and densification during compression and on compactability of microcrystalline cellulose pellets. Int. J. Pharm. 163 (1998) 35-48
7. Jono K., Ichikawa H., Miyamoto M., and Fukumori Y. A review of particulate design for pharmaceutical powders and their production by spouted bed coating. Powder Technol. 113 (2000) 269-277
8. Maronga S.J., and Wnukowski P. The use of humidity and temperature profiles in optimizing the size of fluidized bed in a coating process. Chem. Eng. Process. 37 (1998) 423-432
9. Ozbey M., and Soylemez M.S. Effect of swirling flow on fluidized bed drying of wheat grains. Energy Convers. Manage. 46 (2005) 1495-1512
10. Ronsse F., Pieters J.G., and Dewettinck K. Combined population balance and thermodynamic modeling of the batch top-spray fluidised bed coating process. Part I. Model development and validation. J. Food Eng. 78 (2007) 296-307
11. Shallcross D.C. Psychrometric charts. In: Shallcross D.C. (Ed). Handbook of Psychrometric Charts: Humidity Diagrams for Engineers (1997), Blackie Academic & Professional, London 44-45
12. Smith P.G., and Nienow A.W. Particle growth mechanisms in fluidized bed granulation. I. The effect of process variables. Chem. Eng. Sci. 38 (1983) 1223-1231
13. Sugito K., Ogata H., Goto H., Noguchi M., Kogure T., Takano M., Maruyama Y., and Sasaki Y. Gastrointestinal transit of non-disintegrating solid formulations in humans. Int. J. Pharm. 60 (1990) 89-97
14. Tang E.S.K., Chan L.W., and Heng P.W.S. Coating of multiparticulates for sustained release. Am. J. Drug Deliv. 3 (2005) 17-28
15. Walter, K., 1998. Apparatus for coating solid particles. US Patent 5,718,764.
16. Wurster, D.E., 1953. Method of applying coating onto edible tablets or the like. US Patent 2,648,609.
17. Yilmaz M., Comakli O., Yapici S., and Sara N. Heat transfer and friction characteristics in decaying swirl flow generated by different radial guide vane swirl generators. Energy Convers. Manage. 44 (2003) 283-300