Yeast two hybrid analyses reveal Novel binary interactions between human cytomegalovirus-encoded virion proteins

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  To, Aaron ^a   Bai, Yong ^a   Shen, Ao ^a   Gong, Hao ^a   Umamoto, Sean ^a   Lu, Sangwei ^a   Liu, Fenyong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; EPITOPE; HYBRID PROTEIN; MYC PROTEIN; PROTEIN; RESTRICTION ENDONUCLEASE; TEGUMENT PROTEIN; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN;

ARTICLE; CODON; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNOPRECIPITATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RNA SEQUENCE; TRANSLATION INITIATION; TWO HYBRID SYSTEM; VIRION; YEAST CELL; CYTOMEGALOVIRUS; GENETICS; HELA CELL; METABOLISM; PROTEIN BINDING;

HERPESVIRIDAE; HUMAN HERPESVIRUS 5; MIRIDAE;

CYTOMEGALOVIRUS; HELA CELLS; HUMANS; IMMUNOPRECIPITATION; OPEN READING FRAMES; PROTEIN BINDING; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL PROTEINS; VIRION;

EID: 79953661477     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017796     Document Type: Article

References (53)

1. Mocarski ES, Shenk T, Pass RF, (2007) Cytomegalovirus. In: Knipe DM, Howley PM, Griffin DE, Martin MA, Lamb RA, editors. Fields Virology Philadelphia, Pa. Lippincott-William & Wilkins pp. 2701-2772.
2. Britt WJ, (1999) Congenital cytomegalovirus infection. In: Hitchcock H, MacKay T, Wasserheit JN, editors. Sexually transmitted diseases and adverse outcomes of pregnancy Washington D.C. ASM Press pp. 269-281.
3. Moorman AC, Holmberg SD, Marlowe SI, Von Bargen JC, Yangco BG, et al. (1999) Changing conditions and treatments in a dynamic cohort of ambulatory HIV patients: the HIV outpatient study (HOPS). Ann Epidemiol 9: 349-357.
4. Jabs DA, Enger C, Bartlett JG, (1989) Cytomegalovirus retinitis and acquired immunodeficiency syndrome. Arch Ophthalmol 107: 75-80.
5. Dolan A, Cunningham C, Hector RD, Hassan-Walker AF, Lee L, et al. (2004) Genetic content of wild-type human cytomegalovirus. J Gen Virol 85: 1301-1312.
6. Murphy E, Yu D, Grimwood J, Schmutz J, Dickson M, et al. (2003) Coding potential of laboratory and clinical strains of human cytomegalovirus. Proc Natl Acad Sci U S A 100: 14976-14981.
7. Dunn W, Chou C, Li H, Hai R, Patterson D, et al. (2003) Functional profiling of human cytomegalovirus genome. Proc Natl Acad Sci U S A 100: 14223-14228.
8. Trus BL, Gibson W, Cheng N, Steven AC, (1999) Capsid structure of simian cytomegalovirus from cryoelectron microscopy: evidence for tegument attachment sites. J Virol 73: 2181-2192.
9. Chen DH, Jiang H, Lee M, Liu F, Zhou ZH, (1999) Three-dimensional visualization of tegument/capsid interactions in the intact human cytomegalovirus. Virology 260: 10-16.
10. Gibson W, (1996) Structure and assembly of the virion. Intervirology 39: 389-400.
11. Liu F, Zhou ZH, eds. (2007) Comparative virion structures of human herpesviruses New York Cambridge University Press pp. 27-43.
12. Varnum SM, Streblow DN, Monroe ME, Smith P, Auberry KJ, et al. (2004) Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome. J Virol 78: 10960-10966.
13. Baldick CJ Jr, Shenk T, (1996) Proteins associated with purified human cytomegalovirus particles. J Virol 70: 6097-6105.
14. Yu X, Trang P, Shah S, Atanasov I, Kim YH, et al. (2005) Dissecting human cytomegalovirus gene function and capsid maturation by ribozyme targeting and electron cryomicroscopy. Proc Natl Acad Sci U S A 102: 7103-7108.
15. Gibson W, Baxter MK, Clopper KS, (1996) Cytomegalovirus "missing" capsid protein identified as heat-aggregable product of human cytomegalovirus UL46. J Virol 70: 7454-7461.
16. Gibson W, Clopper KS, Britt WJ, Baxter MK, (1996) Human cytomegalovirus (HCMV) smallest capsid protein identified as product of short open reading frame located between HCMV UL48 and UL49. J Virol 70: 5680-5683.
17. Loveland AN, Nguyen NL, Brignole EJ, Gibson W, (2007) The amino-conserved domain of human cytomegalovirus UL80a proteins is required for key interactions during early stages of capsid formation and virus production. J Virol 81: 620-628.
18. Wood LJ, Baxter MK, Plafker SM, Gibson W, (1997) Human cytomegalovirus capsid assembly protein precursor (pUL80.5) interacts with itself and with the major capsid protein (pUL86) through two different domains. J Virol 71: 179-190.
19. Lai L, Britt WJ, (2003) The interaction between the major capsid protein and the smallest capsid protein of human cytomegalovirus is dependent on two linear sequences in the smallest capsid protein. J Virol 77: 2730-2735.
20. Phillips SL, Bresnahan WA, (2010) Identification of binary interactions between human cytomegalovirus virion proteins. J Virol In press.
21. Calderwood MA, Venkatesan K, Xing L, Chase MR, Vazquez A, et al. (2007) Epstein-Barr virus and virus human protein interaction maps. Proc Natl Acad Sci U S A 104: 7606-7611.
22. Uetz P, Dong YA, Zeretzke C, Atzler C, Baiker A, et al. (2006) Herpesviral protein networks and their interaction with the human proteome. Science 311: 239-242.
23. Rozen R, Sathish N, Li Y, Yuan Y, (2008) Virion-wide protein interactions of Kaposi's sarcoma-associated herpesvirus. J Virol 82: 4742-4750.
24. Fossum E, Friedel CC, Rajagopala SV, Titz B, Baiker A, et al. (2009) Evolutionarily conserved herpesviral protein interaction networks. PLoS Pathog 5: e1000570.
25. Fields S, Song O, (1989) A novel genetic system to detect protein-protein interactions. Nature 340: 245-246.
26. Rain JC, Selig L, De Reuse H, Battaglia V, Reverdy C, et al. (2001) The protein-protein interaction map of Helicobacter pylori. Nature 409: 211-215.
27. Li S, Armstrong CM, Bertin N, Ge H, Milstein S, et al. (2004) A map of the interactome network of the metazoan C. elegans. Science 303: 540-543.
28. LaCount DJ, Vignali M, Chettier R, Phansalkar A, Bell R, et al. (2005) A protein interaction network of the malaria parasite Plasmodium falciparum. Nature 438: 103-107.
29. Ito T, Chiba T, Ozawa R, Yoshida M, Hattori M, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interactome. Proc Natl Acad Sci U S A 98: 4569-4574.
30. Giot L, Bader JS, Brouwer C, Chaudhuri A, Kuang B, et al. (2003) A protein interaction map of Drosophila melanogaster. Science 302: 1727-1736.
31. McCraith S, Holtzman T, Moss B, Fields S, (2000) Genome-wide analysis of vaccinia virus protein-protein interactions. Proc Natl Acad Sci U S A 97: 4879-4884.
32. Marchini A, Liu H, Zhu H, (2001) Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes. J Virol 75: 1870-1878.
33. Dunn W, Trang P, Zhong Q, Yang E, van Belle C, et al. (2005) Human cytomegalovirus expresses novel microRNAs during productive viral infection. Cell Microbiol 7: 1684-1695.
34. Davison AJ, Dolan A, Akter P, Addison C, Dargan DJ, et al. (2003) The human cytomegalovirus genome revisited: comparison with the chimpanzee cytomegalovirus genome. J Gen Virol 84: 17-28.
35. Chee MS, Bankier AT, Beck S, Bohni R, Brown CM, et al. (1990) Analysis of the protein-coding content of the sequence of human cytomegalovirus strain AD169. Curr Top Microbiol Immunol 154: 125-169.
36. Lischka P, Thomas M, Toth Z, Mueller R, Stamminger T, (2007) Multimerization of human cytomegalovirus regulatory protein UL69 via a domain that is conserved within its herpesvirus homologues. J Gen Virol 88: 405-410.
37. Cusick ME, Klitgord N, Vidal M, Hill DE, (2005) Interactome: gateway into systems biology. Hum Mol Genet 14 Spec No. 2: R171-181.
38. Vittone V, Diefenbach E, Triffett D, Douglas MW, Cunningham AL, et al. (2005) Determination of interactions between tegument proteins of herpes simplex virus type 1. J Virol 79: 9566-9571.
39. Park MY, Kim YE, Seo MR, Lee JR, Lee CH, et al. (2006) Interactions among four proteins encoded by the human cytomegalovirus UL112-113 region regulate their intranuclear targeting and the recruitment of UL44 to prereplication foci. J Virol 80: 2718-2727.
40. Klupp BG, Fuchs W, Granzow H, Nixdorf R, Mettenleiter TC, (2002) Pseudorabies virus UL36 tegument protein physically interacts with the UL37 protein. J Virol 76: 3065-3071.
41. Desai P, Person S, (1996) Molecular interactions between the HSV-1 capsid proteins as measured by the yeast two-hybrid system. Virology 220: 516-521.
42. Okoye ME, Sexton GL, Huang E, McCaffery JM, Desai P, (2006) Functional analysis of the triplex proteins (VP19C and VP23) of herpes simplex virus type 1. J Virol 80: 929-940.
43. Greis KD, Gibson W, Hart GW, (1994) Site-specific glycosylation of the human cytomegalovirus tegument basic phosphoprotein (UL32) at serine 921 and serine 952. J Virol 68: 8339-8349.
44. Adair R, Douglas ER, Maclean JB, Graham SY, Aitken JD, et al. (2002) The products of human cytomegalovirus genes UL23, UL24, UL43 and US22 are tegument components. J Gen Virol 83: 1315-1324.
45. Schierling K, Stamminger T, Mertens T, Winkler M, (2004) Human cytomegalovirus tegument proteins ppUL82 (pp71) and ppUL35 interact and cooperatively activate the major immediate-early enhancer. J Virol 78: 9512-9523.
46. Yu D, Silva MC, Shenk T, (2003) Functional map of human cytomegalovirus AD169 defined by global mutational analysis. Proc Natl Acad Sci U S A 100: 12396-12401.
47. Schnee M, Ruzsics Z, Bubeck A, Koszinowski UH, (2006) Common and specific properties of herpesvirus UL34/UL31 protein family members revealed by protein complementation assay. J Virol 80: 11658-11666.
48. Muranyi W, Haas J, Wagner M, Krohne G, Koszinowski UH, (2002) Cytomegalovirus recruitment of cellular kinases to dissolve the nuclear lamina. Science 297: 854-857.
49. Spaderna S, Kropff B, Kodel Y, Shen S, Coley S, et al. (2005) Deletion of gpUL132, a structural component of human cytomegalovirus, results in impaired virus replication in fibroblasts. J Virol 79: 11837-11847.
50. Wang D, Bresnahan W, Shenk T, (2004) Human cytomegalovirus encodes a highly specific RANTES decoy receptor. Proc Natl Acad Sci U S A 101: 16642-16647.
51. Mackay JP, Sunde M, Lowry JA, Crossley M, Matthews JM, (2007) Protein interactions: is seeing believing? Trends Biochem Sci 32: 530-531.
52. Trang P, Lee M, Nepomuceno E, Kim J, Zhu H, et al. (2000) Effective inhibition of human cytomegalovirus gene expression and replication by a ribozyme derived from the catalytic RNA subunit of RNase P from Escherichia coli. Proc Natl Acad Sci U S A 97: 5812-5817.
53. Dunn W, Trang P, Khan U, Zhu J, Liu F, (2001) RNase P-mediated inhibition of cytomegalovirus protease expression and viral DNA encapsidation by oligonucleotide external guide sequences. Proc Natl Acad Sci U S A 98: 14831-14836.