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Volumn 24, Issue 4, 2011, Pages 487-494

Regional immunity in melanoma: Immunosuppressive changes precede nodal metastasis

Author keywords

angiogenesis; cytotoxic T cells; lymph nodes; melanoma; regional immunity

Indexed keywords

BIOLOGICAL MARKER; CD123 ANTIGEN; CD14 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD8 ANTIGEN; CD86 ANTIGEN; GALECTIN 3; GLYCOPROTEIN; HLA DR ANTIGEN; HLA G ANTIGEN; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 10; LYVE PROTEIN; OSTEOPONTIN; PLACENTAL GROWTH FACTOR; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; UNCLASSIFIED DRUG; VASCULOTROPIN C; VASCULOTROPIN RECEPTOR 3;

EID: 79953303193     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2010.227     Document Type: Article
Times cited : (51)

References (59)
  • 3
    • 34548670729 scopus 로고    scopus 로고
    • The role of sentinel lymph node biopsy in the management of melanoma
    • Amersi F, Morton DL. The role of sentinel lymph node biopsy in the management of melanoma. Adv Surg 2007;41:241-256.
    • (2007) Adv Surg , vol.41 , pp. 241-256
    • Amersi, F.1    Morton, D.L.2
  • 5
    • 63549104097 scopus 로고    scopus 로고
    • Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma
    • Nevala WK, Vachon CM, Leontovich AA, et al. Evidence of systemic Th2-driven chronic inflammation in patients with metastatic melanoma. Clin Cancer Res 2009;15:1931-1939.
    • (2009) Clin Cancer Res , vol.15 , pp. 1931-1939
    • Nevala, W.K.1    Vachon, C.M.2    Leontovich, A.A.3
  • 8
    • 25644432763 scopus 로고    scopus 로고
    • Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer
    • Kohrt HE, Nouri N, Nowels K, et al. Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer. PLoS Med 2005;2:e284.
    • (2005) PLoS Med , vol.2
    • Kohrt, H.E.1    Nouri, N.2    Nowels, K.3
  • 10
    • 52549083059 scopus 로고    scopus 로고
    • Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood
    • Jandus C, Bioley G, Speiser DE, et al. Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood. Cancer Immunol Immunother 2008;57:1795-1805.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1795-1805
    • Jandus, C.1    Bioley, G.2    Speiser, D.E.3
  • 12
    • 68849129604 scopus 로고    scopus 로고
    • Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
    • Mansfield AS, Heikkila PS, Vaara AT, et al. Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer. BMC Cancer 2009;9:231.
    • (2009) BMC Cancer , vol.9 , pp. 231
    • Mansfield, A.S.1    Heikkila, P.S.2    Vaara, A.T.3
  • 13
    • 70449441725 scopus 로고    scopus 로고
    • FOXP3 expression of micrometastasis-positive sentinel nodes in breast cancer patients
    • Matsuura K, Yamaguchi Y, Osaki A, et al. FOXP3 expression of micrometastasis-positive sentinel nodes in breast cancer patients. Oncol Rep 2009;22: 1181-1187.
    • (2009) Oncol Rep , vol.22 , pp. 1181-1187
    • Matsuura, K.1    Yamaguchi, Y.2    Osaki, A.3
  • 14
    • 33644836887 scopus 로고    scopus 로고
    • Maturation of dendritic cells and T-cell responses in sentinel lymph nodes from patients with breast carcinoma
    • DOI 10.1002/cncr.21729
    • Matsuura K, Yamaguchi Y, Ueno H, et al. Maturation of dendritic cells and T-cell responses in sentinel lymph nodes from patients with breast carcinoma. Cancer 2006;106:1227-1236. (Pubitemid 43363898)
    • (2006) Cancer , vol.106 , Issue.6 , pp. 1227-1236
    • Matsuura, K.1    Yamaguchi, Y.2    Ueno, H.3    Osaki, A.4    Arihiro, K.5    Toge, T.6
  • 15
    • 38049129212 scopus 로고    scopus 로고
    • Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma
    • Vence L, Palucka AK, Fay JW, et al. Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma. Proc Natl Acad Sci USA 2007;104:20884-20889.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20884-20889
    • Vence, L.1    Palucka, A.K.2    Fay, J.W.3
  • 16
    • 65349149089 scopus 로고    scopus 로고
    • Molecular mechanism and function of CD40/CD40L engagement in the immune system
    • Elgueta R, Benson MJ, de Vries VC, et al. Molecular mechanism and function of CD40/CD40L engagement in the immune system. Immunol Rev 2009;229: 152-172.
    • (2009) Immunol Rev , vol.229 , pp. 152-172
    • Elgueta, R.1    Benson, M.J.2    De Vries, V.C.3
  • 18
    • 2542471742 scopus 로고    scopus 로고
    • Down-regulation of HLA II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients
    • DOI 10.1007/s00262-003-0489-1
    • Ugurel S, Uhlig D, Pfohler C, et al. Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients. Cancer Immunol Immunother 2004;53:551-559. (Pubitemid 38680262)
    • (2004) Cancer Immunology, Immunotherapy , vol.53 , Issue.6 , pp. 551-559
    • Ugurel, S.1    Uhlig, D.2    Pfohler, C.3    Tilgen, W.4    Schadendorf, D.5    Reinhold, U.6
  • 19
    • 0036358039 scopus 로고    scopus 로고
    • Dendritic cell function in sentinel nodes
    • Essner R, Kojima M. Dendritic cell function in sentinel nodes. Oncology (Williston Park) 2002;16:27-31.
    • (2002) Oncology (Williston Park) , vol.16 , pp. 27-31
    • Essner, R.1    Kojima, M.2
  • 20
    • 7044272595 scopus 로고    scopus 로고
    • Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer
    • Poindexter NJ, Sahin A, Hunt KK, et al. Analysis of dendritic cells in tumor-free and tumor-containing sentinel lymph nodes from patients with breast cancer. Breast Cancer Res 2004;6:R408-R415.
    • (2004) Breast Cancer Res , vol.6
    • Poindexter, N.J.1    Sahin, A.2    Hunt, K.K.3
  • 21
    • 0034979375 scopus 로고    scopus 로고
    • Sentinel lymph nodes show profound downregulation of antigen-presenting cells of the paracortex: Implications for tumor biology and treatment
    • DOI 10.1038/modpathol.3880358
    • Cochran AJ, Morton DL, Stern S, et al. Sentinel lymph nodes show profound downregulation of antigenpresenting cells of the paracortex: implications for tumor biology and treatment. Mod Pathol 2001;14: 604-608. (Pubitemid 32554086)
    • (2001) Modern Pathology , vol.14 , Issue.6 , pp. 604-608
    • Cochran, A.J.1    Morton, D.L.2    Stern, S.3    Lana, A.M.A.4    Essner, R.5    Wen, D.-R.6
  • 27
    • 0026846928 scopus 로고
    • The role of angiogenesis in tumor growth
    • Folkman J. The role of angiogenesis in tumor growth. Semin Cancer Biol 1992;3:65-71.
    • (1992) Semin Cancer Biol , vol.3 , pp. 65-71
    • Folkman, J.1
  • 29
    • 36849078591 scopus 로고    scopus 로고
    • Angiogenesis in Melanoma
    • DOI 10.1053/j.seminoncol.2007.09.009, PII S0093775407001832, Malignant Melanoma
    • Mahabeleshwar GH, Byzova TV. Angiogenesis in melanoma. Semin Oncol 2007;34:555-565. (Pubitemid 350236307)
    • (2007) Seminars in Oncology , vol.34 , Issue.6 , pp. 555-565
    • Mahabeleshwar, G.H.1    Byzova, T.V.2
  • 30
    • 33746012247 scopus 로고    scopus 로고
    • Tumor lymphangiogenesis and metastatic spread - New players begin to emerge
    • DOI 10.1002/ijc.21899
    • Achen MG, Stacker SA. Tumor lymphangiogenesis and metastatic spread-new players begin to emerge. Int J Cancer 2006;119:1755-1760. (Pubitemid 44356830)
    • (2006) International Journal of Cancer , vol.119 , Issue.8 , pp. 1755-1760
    • Achen, M.G.1    Stacker, S.A.2
  • 31
    • 33846857321 scopus 로고    scopus 로고
    • VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites
    • DOI 10.1182/blood-2006-05-021758
    • Hirakawa S, Brown LF, Kodama S, et al. VEGF-Cinduced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites. Blood 2007;109:1010-1017. (Pubitemid 46220646)
    • (2007) Blood , vol.109 , Issue.3 , pp. 1010-1017
    • Hirakawa, S.1    Brown, L.F.2    Kodama, S.3    Paavonen, K.4    Alitalo, K.5    Detmar, M.6
  • 33
    • 34247278601 scopus 로고    scopus 로고
    • Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angio- and lymphangiogenesis
    • DOI 10.1038/sj.bjc.6603678, PII 6603678
    • Mohammed RA, Green A, El-Shikh S, et al. Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angio-and lymphangiogenesis. Br J Cancer 2007;96:1092-1100. (Pubitemid 46608319)
    • (2007) British Journal of Cancer , vol.96 , Issue.7 , pp. 1092-1100
    • Mohammed, R.A.A.1    Green, A.2    El-Shikh, S.3    Paish, E.C.4    Ellis, I.O.5    Martin, S.G.6
  • 40
    • 51749113339 scopus 로고    scopus 로고
    • The role of VEGF-C staining in predicting regional metastasis in melanoma
    • Boone B, Blokx W, De Bacquer D, et al. The role of VEGF-C staining in predicting regional metastasis in melanoma. Virchows Arch 2008;453:257-265.
    • (2008) Virchows Arch , vol.453 , pp. 257-265
    • Boone, B.1    Blokx, W.2    De Bacquer, D.3
  • 41
    • 33645991795 scopus 로고    scopus 로고
    • Tumourassociated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • Sica A, Schioppa T, Mantovani A, et al. Tumourassociated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 2006;42: 717-727.
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3
  • 42
    • 71249138054 scopus 로고    scopus 로고
    • Cancer and pregnancy: Parallels in growth, invasion, and immune modulation and implications for cancer therapeutic agents
    • Holtan SG, Creedon DJ, Haluska P, et al. Cancer and pregnancy: parallels in growth, invasion, and immune modulation and implications for cancer therapeutic agents. Mayo Clin Proc 2009;84:985-1000.
    • (2009) Mayo Clin Proc , vol.84 , pp. 985-1000
    • Holtan, S.G.1    Creedon, D.J.2    Haluska, P.3
  • 43
    • 52149088558 scopus 로고    scopus 로고
    • Molecular mechanisms of metastasis
    • Weber GF. Molecular mechanisms of metastasis. Cancer Lett 2008;270:181-190.
    • (2008) Cancer Lett , vol.270 , pp. 181-190
    • Weber, G.F.1
  • 44
    • 33745700699 scopus 로고    scopus 로고
    • Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer
    • Allan AL, George R, Vantyghem SA, et al. Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer. Am J Pathol 2006;169: 233-246.
    • (2006) Am J Pathol , vol.169 , pp. 233-246
    • Allan, A.L.1    George, R.2    Vantyghem, S.A.3
  • 45
    • 57149104573 scopus 로고    scopus 로고
    • Expression profiling of Galectin-3-depleted melanoma cells reveals its major role in melanoma cell plasticity and vasculogenic mimicry
    • Mourad-Zeidan AA, Melnikova VO, Wang H, et al. Expression profiling of Galectin-3-depleted melanoma cells reveals its major role in melanoma cell plasticity and vasculogenic mimicry. Am J Pathol 2008;173: 1839-1852.
    • (2008) Am J Pathol , vol.173 , pp. 1839-1852
    • Mourad-Zeidan, A.A.1    Melnikova, V.O.2    Wang, H.3
  • 46
    • 73349088135 scopus 로고    scopus 로고
    • Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients
    • Vereecken P, Awada A, Suciu S, et al. Evaluation of the prognostic significance of serum galectin-3 in American Joint Committee on Cancer stage III and stage IV melanoma patients. Melanoma Res 2009;19:316-320.
    • (2009) Melanoma Res , vol.19 , pp. 316-320
    • Vereecken, P.1    Awada, A.2    Suciu, S.3
  • 48
    • 74949143594 scopus 로고    scopus 로고
    • Final version of 2009 AJCC melanoma staging and classification
    • Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009;27:6199-6206.
    • (2009) J Clin Oncol , vol.27 , pp. 6199-6206
    • Balch, C.M.1    Gershenwald, J.E.2    Soong, S.J.3
  • 50
    • 50649089386 scopus 로고    scopus 로고
    • Identification of CD123+myeloid dendritic cells as an early-stage immature subset with strong tumoristatic potential
    • Shi J, Ikeda K, Maeda Y, et al. Identification of CD123+myeloid dendritic cells as an early-stage immature subset with strong tumoristatic potential. Cancer Lett 2008;270:19-29.
    • (2008) Cancer Lett , vol.270 , pp. 19-29
    • Shi, J.1    Ikeda, K.2    Maeda, Y.3
  • 51
    • 33750571162 scopus 로고    scopus 로고
    • Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors
    • DOI 10.1097/01.cji.0000211312.36363.56, PII 0000237120061100000005
    • Lotem M, Zhao Y, Riley J, et al. Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors. J Immunother 2006;29: 616-627. (Pubitemid 44674045)
    • (2006) Journal of Immunotherapy , vol.29 , Issue.6 , pp. 616-627
    • Lotem, M.1    Zhao, Y.2    Riley, J.3    Hwu, P.4    Morgan, R.A.5    Rosenberg, S.A.6    Parkhurst, M.R.7
  • 53
    • 23744454704 scopus 로고    scopus 로고
    • Differential regulation of the IL-10 gene in Th1 and Th2 T cells
    • Kang KH, Im SH. Differential regulation of the IL-10 gene in Th1 and Th2 T cells. Ann NY Acad Sci 2005; 1050:97-107.
    • (2005) Ann NY Acad Sci , vol.1050 , pp. 97-107
    • Kang, K.H.1    Im, S.H.2
  • 54
    • 0030118083 scopus 로고    scopus 로고
    • Erratum: A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases (The EMBO Journal (1996) 15 (290-298))
    • Joukov V, Pajusola K, Kaipainen A, et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for the Flt4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBOJ 1996;15:1751. (Pubitemid 26112397)
    • (1996) EMBO Journal , vol.15 , Issue.7 , pp. 1751
    • Jsukov, V.1    Pajusola, K.2    Kaipainen, A.3    Chilov, D.4    Lahtinen, I.5    Kukk, E.6    Saksela, O.7    Kalkkinen, N.8    Alitalo, K.9
  • 56
    • 16844365788 scopus 로고    scopus 로고
    • + regulatory T cells in immunological tolerance to self and non-self
    • DOI 10.1038/ni1178
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005;6:345-352. (Pubitemid 41716771)
    • (2005) Nature Immunology , vol.6 , Issue.4 , pp. 345-352
    • Sakaguchi, S.1
  • 57
    • 70449571945 scopus 로고    scopus 로고
    • The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes
    • Jenner RG, Townsend MJ, Jackson I, et al. The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes. Proc Natl Acad Sci USA 2009;106:17876-17881.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 17876-17881
    • Jenner, R.G.1    Townsend, M.J.2    Jackson, I.3
  • 58


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