Targeted mutations in the Na,K-ATPase alpha 2 isoform confer ouabain resistance and result in abnormal behavior in mice

Synapse

Volumn 65, Issue 6, 2011, Pages 520-531

  Schaefer, Tori L ^a   Lingrel, Jerry B ^a   Moseley, Amy E ^a,b   Vorhees, Charles V ^a,c   Williams, Michael T ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MONSANTO COMPANY   (United States)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

Author keywords

Acoustic startle response; Dopamine; Egocentric learning; Methamphetamine induced locomotor activity; Na K ATPase; Ouabain

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); METHAMPHETAMINE; OUABAIN;

ABNORMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; BRAIN FUNCTION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME SUBUNIT; GENE MUTATION; LEARNING; LOCOMOTION; MALE; MEMORY; MOUSE; NONHUMAN; PRIORITY JOURNAL; STARTLE REFLEX;

ANIMALS; BEHAVIOR, ANIMAL; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE; GENE KNOCK-IN TECHNIQUES; ISOENZYMES; MALE; MICE; MICE, 129 STRAIN; MICE, TRANSGENIC; OUABAIN; RANDOM ALLOCATION; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 79953271907     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.20870     Document Type: Article

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