Cytotoxic T cells - Stroma interactions

Bulletin du Cancer

Volumn 98, Issue 2, 2011, Pages

  Noman, Muhammad Zaeem ^a   Benlalam, Houssem ^a   Hasmim, Meriem ^a   Chouaib, Salem ^a  

^a Unite Inst Natl de la S et de la Rech Med U753 Immunol des Tumeurs Humaines   (France)

Author keywords

CTLs; Endothelial cells; HIF 1 ; Hypoxia; STAT3; Tumor cells

Indexed keywords

STAT3 PROTEIN;

CYTOTOXIC T LYMPHOCYTE; ENDOTHELIUM CELL; HUMAN; HYPOXIA; IMMUNE RESPONSE; REVIEW; STROMA; TUMOR MICROENVIRONMENT;

EID: 79953252690     PISSN: 00074551     EISSN: 17696917     Source Type: Journal    
DOI: 10.1684/bdc.2010.1295     Document Type: Review

References (44)

1. Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002 ; 2 : 38-47. (Pubitemid 37328806)
2. Semenza GL. Chairman's summary: mechanisms of oxygen homeostasis, circa 1999. Adv Exp Med Biol 2000 ; 475 : 303-10. (Pubitemid 32197735)
3. Semenza GL. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 2003 ; 3 : 721-32. (Pubitemid 37328811)
4. Keith B, Simon MC. Hypoxia-inducible factors, stem cells, and cancer. Cell 2007 ; 129 : 465-72. (Pubitemid 46660978)
5. Lukashev D, Ohta A, Sitkovsky M. Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues. Cancer Metastasis Rev 2007 ; 26 : 273-9. (Pubitemid 47101659)
6. Sullivan R, Graham CH. Hypoxia-driven selection of the metastatic phenotype. Cancer Metastasis Rev 2007 ; 26 : 319-31.
7. Volm M, Koomagi R. Hypoxia-inducible factor (HIF-1) and its relationship to apoptosis and proliferation in lung cancer. Anticancer Res 2000 ; 20 : 1527-33. (Pubitemid 30628160)
8. Liu XH. HIF-1alpha has an anti-apoptotic effect in human airway epithelium that is mediated via Mcl-1 gene expression. J Cell Biochem 2006 ; 97 : 755-65.
9. Fink T. Natural killer cell-mediated basal and interferon-enhanced cytotoxicity against liver cancer cells is significantly impaired under in vivo oxygen conditions. Scand J Immunol 2003 ; 58 : 607-12. (Pubitemid 37521935)
10. Siemens DR. Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: role of nitric oxide. Cancer Res 2008 ; 68 : 4746-53.
11. Lorusso G, Ruegg C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem Cell Biol 2008 ; 130 : 1091-103.
12. Petrulio CA, Kim-Schulze S, Kaufman HL. The tumour microenvironment and implications for cancer immunotherapy. Expert Opin Biol Ther 2006 ; 6 : 671-84.
13. Mrass P. Random migration precedes stable target cell interactions of tumor-infiltrating T cells. J Exp Med 2006 ; 203 : 2749-61. (Pubitemid 44833350)
14. Johnson JP. Identification of molecules associated with the development of metastasis in human malignant melanoma. Invasion Metastasis 1994 ; 14 : 123-30.
15. Hamai A. Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune? Tissue Antigens 2010 ; 75 : 1-8.
16. Dini L. Phagocytosis of apoptotic bodies by liver endothelial cells. J Cell Sci 1995 ; 108(Pt 3) : 967-73.
17. Berg M. Cross-presentation of antigens from apoptotic tumor cells by liver sinusoidal endothelial cells leads to tumor-specific CD8+ T cell tolerance. Eur J Immunol 2006 ; 36 : 2960-70.
18. Hristov M. Apoptotic bodies from endothelial cells enhance the number and initiate the differentiation of human endothelial progenitor cells in vitro. Blood 2004 ; 104 : 2761-6. (Pubitemid 39434959)
19. Valujskikh A. Cross-primed CD8(+) T cells mediate graft rejection via a distinct effector pathway. Nat Immunol 2002 ; 3 : 844-51.
20. Savinov AY. Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells. J Exp Med 2003 ; 197 : 643-56. (Pubitemid 36314659)
21. Limmer A. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance. Nat Med 2000 ; 6 : 1348-54. (Pubitemid 32001018)
22. Mancuso P. Validation of a standardized method for enumerating circulating endothelial cells and progenitors: flow cytometry and molecular and ultrastructural analyses. Clin Cancer Res 2009 ; 15 : 267-73.
23. Sun Y. The kinase insert domain-containing receptor is an angiogenesis-associated antigen recognized by human cytotoxic T lymphocytes. Blood 2006 ; 107 : 1476-83. (Pubitemid 43242384)
24. Noman MZ. The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis. J Immunol 2009 ; 182 : 3510-21.
25. Yu H, Kortylewski M, Pardoll D. Crosstalk between cancer and immune cells: role of STAT3 in the tumour microenvironment. Nat Rev Immunol 2007 ; 7 : 41-51. (Pubitemid 46020826)
26. Wang T. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nat Med 2004 ; 10 : 48-54. (Pubitemid 38524698)
27. Gabrilovich DI. Antibodies to vascular endothelial growth factor enhance the efficacy of cancer immunotherapy by improving endogenous dendritic cell function. Clin Cancer Res 1999 ; 5 : 2963-70. (Pubitemid 29493976)
28. Nair S. Synergy between tumor immunotherapy and antiangiogenic therapy. Blood 2003 ; 102 : 964-71. (Pubitemid 36917791)
29. Chouaib S. Integrating the quality of the cytotoxic response and tumor susceptibility into the design of protective vaccines in tumor immunotherapy. J Clin Invest 2003 ; 111 : 595-7. (Pubitemid 36278575)
30. Benlalam H. Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL. J Immunol 2009 ; 182 : 2654-64.
31. Hussain SF. A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients. Cancer Res 2007 ; 67 : 9630-6. (Pubitemid 47621208)
32. Xin H. Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. Cancer Res 2009 ; 69 : 2506-13.
33. Ozao-Choy J. The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer Res 2009 ; 69 : 2514-22.
34. Ma W, Pober JS. Human endothelial cells effectively costimulate cytokine production by, but not differentiation of, naive CD4+ T cells. J Immunol 1998 ; 161 : 2158-67. (Pubitemid 28397025)
35. Khayyamian S. ICOS-ligand, expressed on human endothelial cells, costimulates Th1 and Th2 cytokine secretion by memory CD4+ T cells. Proc Natl Acad Sci U S A 2002 ; 99 : 6198-203. (Pubitemid 34493289)
36. Marelli-Berg FM. Activated murine endothelial cells have reduced immunogenicity for CD8+ T cells: a mechanism of immunoregulation?. J Immunol 2000 ; 165 : 4182-9.
37. Katz SC. Liver sinusoidal endothelial cells are insufficient to activate T cells. J Immunol 2004 ; 173 : 230-5. (Pubitemid 38797346)
38. Dengler TJ, Pober JS. Human vascular endothelial cells stimulate memory but not naive CD8+ T cells to differentiate into CTL retaining an early activation phenotype. J Immunol 2000 ; 164 : 5146-55. (Pubitemid 30305190)
39. Marelli-Berg FM. Antigen recognition influences transendothelial migration of CD4+ T cells. J Immunol 1999 ; 162 : 696-703.
40. Pober JS, Kluger MS, Schechner JS. Human endothelial cell presentation of antigen and the homing of memory/effector T cells to skin. Ann N Y Acad Sci 2001 ; 941 : 12-25. (Pubitemid 32928329)
41. Ferry B. Impact of class II major histocompatibility complex antigen expression on the immunogenic potential of isolated rat vascular endothelial cells. Transplantation 1987 ; 44 : 499-503. (Pubitemid 17154146)
42. Okaji Y. Vaccination with autologous endothelium inhibits angiogenesis and metastasis of colon cancer through autoimmunity. Cancer Sci 2004 ; 95 : 85-90. (Pubitemid 38208412)
43. Yoneyama S. A study of dendritic and endothelial cell interactions in colon cancer in a cell line and small mammal model. Eur J Surg Oncol 2007 ; 33 : 1191-8. (Pubitemid 350091344)
44. Neijssen J, Herberts C, Drijfhout JW, et al. Cross-presentation by intercellular peptide transfer through gap junctions. Nature 2005 ; 434 : 83-8. (Pubitemid 40349389)