Evaluation of strain-induced hydrophobicity of pharmaceutical blends and its effect on drug release rate under multiple compression conditions

Drug Development and Industrial Pharmacy

Volumn 37, Issue 4, 2011, Pages 428-435

  Pingali, Kalyana ^a   Mendez, Rafael ^a   Lewis, Daniel ^a   Michniak Kohn, Bozena ^b   Cuitiño, Alberto ^b   Muzzio, Fernando ^a  

^a The State University of New Jersey   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

Colloidal silica; dissolution; drug release; hydrophobicity; shear

Indexed keywords

EXCIPIENT; MAGNESIUM STEARATE;

ARTICLE; DISSOLUTION; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; HYDROPHOBICITY; PARTICLE SIZE; POWDER; SHEAR FLOW; TABLET COMPRESSION; TABLET FORMULATION;

HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; PARTICLE SIZE; POWDERS; SILICON DIOXIDE; SOLUBILITY; STEARIC ACIDS; STRESS, MECHANICAL; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 79953249836     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2010.521160     Document Type: Article

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