Structural basis of species differences between human and experimental animal CYP1A1s in metabolism of 3,3′,4,4′,5-pentachlorobiphenyl

Journal of Biochemistry

Volumn 149, Issue 4, 2011, Pages 487-494

  Yamazaki, Kiyoshi ^a   Suzuki, Motoharu ^a,b   Itoh, Toshimasa ^c   Yamamoto, Keiko ^c   Kanemitsu, Miki ^a   Matsumura, Chisato ^b   Nakano, Takeshi ^b   Sakaki, Toshiyuki ^d   Fukami, Yasuo ^a   Imaishi, Hiromasa ^a   Inui, Hideyuki ^a  

^a KOBE UNIVERSITY   (Japan)

^b Hyogo Environmental Advancement Association   (Japan)

^c SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

^d TOYAMA PREFECTURAL UNIVERSITY   (Japan)

Author keywords

cytochrome P450; docking approach; homology modelling; persistent organic pollutants; polychlorinated biphenyl

Indexed keywords

3,3',4,4',5 PENTACHLOROBIPHENYL; AMINO ACID; CYTOCHROME P450 1A1; TETRACHLOROBIPHENYL;

ANIMAL CELL; ARTICLE; COMPARATIVE STUDY; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; EXPERIMENTAL ANIMAL; HUMAN; HUMAN CELL; INTRODUCED SPECIES; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; XENOBIOTIC METABOLISM;

ANIMALIA; MAMMALIA; RATTUS;

EID: 79953229211     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvr009     Document Type: Article

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