Thr270Ile in embC (Rv3793) is not a marker for ethambutol resistance in the Mycobacterium tuberculosis complex

Antimicrobial Agents and Chemotherapy

Volumn 55, Issue 4, 2011, Pages 1825-

  Köser, Claudio U ^a   Summers, David K ^a   Archer, John A C ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; EMBC PROTEIN; ETHAMBUTOL; ISOLEUCINE; THREONINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL STRAIN; GENE MUTATION; GEOGRAPHICAL VARIATION (SPECIES); LETTER; MYCOBACTERIUM AFRICANUM; MYCOBACTERIUM AVIUM; MYCOBACTERIUM BOVIS; MYCOBACTERIUM MARINUM; MYCOBACTERIUM TUBERCULOSIS; MYCOBACTERIUM ULCERANS; NONHUMAN; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AMINO ACID SEQUENCE; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; ETHAMBUTOL; LIPOPOLYSACCHARIDES; MYCOBACTERIUM TUBERCULOSIS; PENTOSYLTRANSFERASES; POINT MUTATION;

EID: 79953212232     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01607-10     Document Type: Letter

References (23)

1. Brosch, R., et al. 2007. Genome plasticity of BCG and impact on vaccine efficacy. Proc. Natl. Acad. Sci. U. S. A. 104:5596-5601.
2. Cole, S. T., et al. 1998. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393:537-544. (Pubitemid 28319235)
3. Comas, I., S. Homolka, S. Niemann, and S. Gagneux. 2009. Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies. PLoS One 4:e7815.
4. Das, S., R. Yennamalli, A. Vishnoi, P. Gupta, and A. Bhattacharya. 2009. Single-nucleotide variations associated with Mycobacterium tuberculosis KwaZulu-Natal strains. J. Biosci. 34:397-404.
5. Fleischmann, R. D., et al. 2002. Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J. Bacteriol. 184:5479-5490. (Pubitemid 35024395)
6. Gagneux, S., and P. M. Small. 2007. Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development. Lancet Infect. Dis. 7:328-337.
7. Galagan, J., et al. 2010. TB database 2010: overview and update. Tuberculosis (Edinb.) 90:225-235.
8. Garnier, T., et al. 2003. The complete genome sequence of Mycobacterium bovis. Proc. Natl. Acad. Sci. U. S. A. 100:7877-7882.
9. Goude, R., A. Amin, D. Chatterjee, and T. Parish. 2009. The arabinosyltransferase EmbC is inhibited by ethambutol in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 53:4138-4146.
10. Hershberg, R., et al. 2008. High functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demography. PLoS Biol. 6:e311.
11. Ioerger, T., et al. 2010. Variation among genome sequences of H37Rv strains of Mycobacterium tuberculosis from multiple laboratories. J. Bacteriol. 192: 3645-3653.
12. Ioerger, T., et al. 2009. Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa. PLoS One 4:e7778.
13. Jadaun, G., et al. 2009. Role of embCAB gene mutations in ethambutol resistance in Mycobacterium tuberculosis isolates from India. Int. J. Antimicrob. Agents 33:483-486.
14. Niemann, S., et al. 2009. Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints. PLoS One 4:e7407.
15. Plinke, C., et al. 2010. embCAB sequence variation among ethambutolresistant Mycobacterium tuberculosis isolates without embB306 mutation. J. Antimicrob. Chemother. 65:1359-1367.
16. Ramaswamy, S. V., et al. 2000. Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 44:326-336.
17. Ritz, N., et al. 2009. Susceptibility of Mycobacterium bovis BCG vaccine strains to antituberculous antibiotics. Antimicrob. Agents Chemother. 53:316-318.
18. Seki, M., et al. 2009. Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guérin (BCG) Tokyo 172: a comparative study of BCG vaccine substrains. Vaccine 27:1710-1716.
19. Sreevatsan, S., et al. 1997. Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations. Antimicrob. Agents Chemother. 41:1677-1681.
20. Srivastava, S., A. Ayyagari, T. Dhole, K. Nyati, and S. Dwivedi. 2009. emb nucleotide polymorphisms and the role of embB306 mutations in Mycobacterium tuberculosis resistance to ethambutol. Int. J. Med. Microbiol. 299:269-280.
21. Srivastava, S., et al. 2006. Nucleotide polymorphism associated with ethambutol resistance in clinical isolates of Mycobacterium tuberculosis. Curr. Microbiol. 53:401-405.
22. Trovero, A., C. Argüelles, and A. Cataldi. 2010. Preparation of a working seed lot of BCG and quality control by PCR genotyping. Rev. Argent. Microbiol. 42:4-10.
23. Zheng, H., et al. 2008. Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. PLoS One 3:e2375.