Whole genome sequence analysis of Mycobacterium bovis bacillus Calmette-Guérin (BCG) Tokyo 172: A comparative study of BCG vaccine substrains

Vaccine

Volumn 27, Issue 11, 2009, Pages 1710-1716

  Seki, Masaaki ^a   Honda, Ikuro ^a   Fujita, Isao ^a   Yano, Ikuya ^a   Yamamoto, Saburo ^a   Koyama, Akira ^a  

^a Kiyose   (Japan)

Author keywords

BCG Tokyo; Complete genomic sequence; Genetic differences

Indexed keywords

BCG VACCINE;

ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; COMPARATIVE STUDY; CONTROLLED STUDY; GENE SEQUENCE; GENETIC VARIABILITY; MYCOBACTERIUM BOVIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; STRAIN DIFFERENCE; VARIABLE NUMBER OF TANDEM REPEAT;

BASE SEQUENCE; BCG VACCINE; DNA, BACTERIAL; GENES, BACTERIAL; GENOME, BACTERIAL; MINISATELLITE REPEATS; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM BOVIS; POLYMORPHISM, SINGLE NUCLEOTIDE; SPECIES SPECIFICITY;

EID: 60849129432     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.01.034     Document Type: Article

References (43)

1. Petroff S.A., Branch A., and Steenken Jr. W. A study of Bacillus Calmette-Guérin (BCG). Am Rev Tuberc 19 (1929) 9-46
2. Behner D.M. The stability of the colony morphology and pathogenicity of BCG. Am Rev Tuberc 31 (1935) 174-202
3. Osborn T.W. Changes in BCG strains. Tuberculosis 64 (1983) 1-13
4. Harboe M., Nagai S., Patarroyo M.E., Torres M.L., Ramirez C., and Cruz N. Properties of proteins MPB64, MPB70, and MPB80 of Mycobacterium bovis BCG. Infect Immun 52 1 (1986) 293-302
5. Wiker H.G., Nagai S., Hewinson R.G., Russell W.P., and Harboe M. Heterogeneous expression of the related MPB70 and MPB83 proteins distinguish various substrains of Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv. Scand J Immunol 43 4 (1996) 374-380
6. Behr M.A., Schroeder B.G., Brinkman J.N., Slayden R.A., and Barry III C.E. A point mutation in the mma3 gene is responsible for impaired methoxymycolic acid production in Mycobacterium bovis BCG strains obtained after 1927. J Bacteriol 182 12 (2000) 3394-3399
7. Hesselberg I. Drug resistance in the Swedish/Norwegian BCG strain. Bull World Health Org 46 (1972) 503-507
8. Buriánková K., Doucet-Populare F., Dorson O., Gondran A., Ghnassia J.C., Weiser J., et al. Molecular basis of intrinsic marolide resistance in the Mycobacterium tuberculosis complex. J Antimicrob Chemother 48 1 (2004) 143-150
9. Grange J.M., and Gilson J.A. Strain to strain variation in the immunogenicity of BCG. Dev Biol Stand 58 (1986) 37-41
10. Lagranderie M.R., Balanzuc A.M., Deriaud E., Leclerc C.D., and Gheorghiu M. Comparison of immune responses of mice immunized with five different Mycobacterium bovis BCG vaccine strains. Infect Immun 64 1 (1996) 1-9
11. Davids V., Hanekom W.A., Mansoor N., Gamieldien H., Gelderbloem S.J., Hawkridge A., et al. The effect of Bacille Calmette-Guérin vaccine strain and route of administration on induced immune responses in vaccinated infants. JID 193 (2006) 531-536
12. Wu B., Huang C., Garcia L., Ponce de Leon A., Osornio J.S., Bobadilla-del-Valle M., et al. Unique gene expression profiles in infants vaccinated with different strains of Mycobacterium bovis Bacille Calmette-Guérin 75 7 (2007) 3658-3664
13. Takeya K., Nomoto K., Muraoka S., Shimotori S., Taniguchi T., and Miyake T. Growth of two strains of Mycobacterium bovis (BCG) in athymic mice. J Gen Microbiol 100 (1977) 403-405
14. Fomukong N.G., Dale J.W., Osborn T.W., and Grange J.M. Use of gene probes based on the insertion sequence IS986 to differentiate between BCG vaccine strains. J Appl Microbiol 72 (1992) 126-133
15. Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D., et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393 (1998) 537-544
16. Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O., Peterson J., et al. Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains. J Bacteriol 184 19 (2002) 5479-5490
17. Garnier T., Eiglmeier K., Camus J.C., Medina N., Mansoor H., Pryor M., et al. The complete genome sequence of Mycobacterium bovis. PNAS 100 13 (2003) 7877-7882
18. Behr M.A., Wilson M.A., Gill W.P., Salamon H., Schoolnik G.K., Rane S., et al. Comparative genomics of BCG vaccines by whole-genome DNA microarray. Science 284 (1999) 1520-1523
19. Mostowy S., Tsolaki A.G., Small P.M., and Behr M.A. The in vitro evolution of BCG vaccines. Vaccine 21 27-30 (2003) 4270-4274
20. Brosch R., Gordon S.V., Garnier T., Eiglmeier K., Frigui W., Valenti P., et al. Genome plasticity of BCG and impact on vaccine efficacy. PNAS 104 13 (2007) 5596-5601
21. Frothingham R., and Meeker-O'Connell A. Genetic diversity in the Mycobacterium tuberculosis complex based on variable numbers of tandem DNA repeats. Microbiology 144 (1998) 1189-1196
22. Smittipat N., Billamas P., Palittapongarnpim M., Thong-On A., Temu M.M., Thanakijcharoen P., et al. Polymorphism of variable-number tandem repeats at multiple loci in Mycobacterium tuberculosis. J Clin Microbiol 43 10 (2005) 5034-5043
23. Brosch R., Gordon S.V., Buchrieser C., Pym A.S., Gamier T., and Cole S.T. Comparative genomics uncovers large tandem chromosomal duplications in Mycobacterium bovis BCG Pasteur. Yeast 17 (2000) 111-123
24. Bedwell J., Kairo S.K., Behr M.A., and Bygraves J.A. Identification of substrains of BCG vaccine using multiplex PCR. Vaccine 19 15-16 (2001) 2146-2151
25. Honda I., Seki M., Ikeda N., Yamamoto S., Yano I., Koyama A., et al. Identification of two subpopulations of bacillus Calmette-Guérin (BCG) Tokyo 172 substrain with different RD16 regions. Vaccine 24 23 (2006) 4969-4974
26. Sassetti C.M., Boyd D.H., and Rubin E.J. Genes required for mycobacterial growth defined by high density mutagenesis. Mol Microbiol 48 (2003) 77-84
27. Magdalena J., Supply P., and Locht C. Specific differentiation between Mycobacterium bovis BCG and virulent strains of the Mycobacterium tuberculosis complex. J Clin Microbiol 36 9 (1998) 2471-2476
28. Parish T., Smith D.A., Roberts G., Betts J., and Stoker N.G. The senX3-regX3 two-component regulatory system of Mycobacterium tuberculosis is required for virulence. Microbiology 149 (2003) 1423-1435
29. Manabe Y.C., Hatem C.L., Kesavan A.K., Durack J., and Murphy R. Both Corynebacterium diphtheriae DtxR (E175K) and Mycobacterium tuberculosis IdeR (D177K) are dominant positive repressors of IdeR-regulated genes in M. tuberculosis. Infect Immun 73 9 (2005) 5988-5994
30. Chanchaem W., and Palittapongarnpim P.A. A variable number of tandem repeats result in polymorphic alpha-isopropylmalate synthase in Mycobacterium tuberculosis. Tuberculosis 82 (2002) 1-6
31. Manganelli R., Dubnau E., Tyagi S., Kramer F.R., and Smith I. Differential expression of 10 sigma factor genes in Mycobacterium tuberculosis. Mol Microbiol 31 2 (1999) 715-724
32. Sreenu V.B., Kumar P., Nagaraju J., and Nagarajaram H.A. Microsatellite polymorphism across the M. tuberculosis and M. bovis genomes: implication on genome evolution and plasticity. BMC Genomics 7 (2006) 78
33. Banu S., Honoré N., Saint-Joanis B., Philpott D., Prévost M.-C., and Cole S.T. Are the PE-PGRS proteins of Mycobacterium tuberculosis variable surface antigens?. Mol Microbiol 44 1 (2002) 9-19
34. Dheenadhayalan V., Delogu G., Sanguinetti M., Fadda G., and Brennan M.J. Variable expression patterns of Mycobacterium tuberculosis PE_PGRS genes: evidence that PE_PGRS16 and PE_PGRS26 are inversely regulated in vivo. J Bacteriol 188 10 (2006) 3721-3725
35. Brennan M., Delogu G., Chen Y., Bardarov S., Kriakov J., Alavi M., et al. Evidence that Mycobacterial PE_PGRS proteins are cell surface constituents that influence interactions with other cells. Infect Immun 69 12 (2001) 7326-7333
36. Brewer T.F., and Colditz G.A. Relationship beween Bacille Calmette-Guérin (BCG) strains and the efficacy of BCG vaccine in the prevention of tuberculosis. CID 20 (1995) 126-135
37. Behr M.A. Correlation between BCG genomics and protective efficacy. Lancet Infect 2 (2002) 86-92
38. Stefanova T., Chouchkova M., Hinds J., Butcher P.D., Inwald J., Dale J., et al. Genetic composition of Mycobacterium bovis BCG substrain Sofia. J Clin Microbiol 41 11 (2003) 5349
39. Charlet D., Mostowy S., Alexander D., Sit L., Wiker H.G., and Behr M.A. Reduced expression of antigenic proteins MPB70 and MPB83 in Mycobacterium bovis BCG strains due to a start codon mutation in sigK. Mol Microbiol 56 5 (2005) 1302-1313
40. Spreadbury C.L., Pallen M.J., Overton T., Behr M.A., Mostowy S., Spiro S., et al. Point mutations in DNA- and cNMP-binding domains of the homologue of the cAMP receptor protein (CRP) in Mycobacterium bovis BCG: implications for the inactivation of a global regulator and strain attenuation. Microbiology 151 (2005) 547-556
41. Bai G., Gazdik M.A., Schaak D.D., and McDonough K.A. The Mycobacterium bovis BCG cyclic AMP receptor-like protein is a functional DNA binding protein in vitro and in vivo, but its activity differs from that of its M. tuberculosis ortholog, Rv3676. Infect Immun 75 11 (2007) 5509-5517
42. Chen J.M., Islam S.T., Ren H., and Liu J. Differential production of lipid virulence factors among BCG vaccine strains and implications on BCG safety. Vaccine 25 48 (2007) 8114-8122
43. Abou-Zeid C., Rook G.A.W., Minnikin D.E., Parlett J.H., Osborn T.W., and Grange J.M. Effect of the method of preparation of Bacille Calmette-Guérin (BCG) vaccine on the properties of four daughter strains. J Appl Bacteriol 63 (1987) 449-453