Diversity of microcystin-producing genotypes in brazilian strains of microcystis (Cyanobacteria);Diversidade de genótipos produtores de microcistinas em linhagens brasileiras de microcystis (Cyanobacteria)

Brazilian Journal of Biology

Volumn 71, Issue 1, 2011, Pages 209-216

  Bittencourt Oliveira, M C ^a   Oliveira, M C ^a   Pinto, E ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

McyB; Microcystin; Toxin; Variants

Indexed keywords

MICROCYSTIN;

ARTICLE; BACTERIAL GENE; BIOSYNTHESIS; BRAZIL; CLASSIFICATION; GENETIC VARIABILITY; GENETICS; GENOTYPE; MICROCYSTIS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYLOGENY;

BASE SEQUENCE; BRAZIL; GENES, BACTERIAL; GENETIC VARIATION; GENOTYPE; MICROCYSTINS; MICROCYSTIS; MOLECULAR SEQUENCE DATA; PHYLOGENY;

CYANOBACTERIA; MICROCYSTIS;

EID: 79953210791     PISSN: 15196984     EISSN: 16784375     Source Type: Journal    
DOI: 10.1590/S1519-69842011000100030     Document Type: Article

References (40)

1. ALTSCHUL, SF., MADDEN, TL., SCHAFFER, AA., ZHANG, J., ZHANG, Z., MILLER, W. and LIPMAN, DJ., 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Research, vol. 25, no. 17, p. 3389-3402.
2. ANJOS, FM., BITTENCOURT-OLIVEIRA, MC., ZAJAC, MP., HILLER, S., CHRISTIAN, B., ERLER, K., LUCKAS, B. and PINTO E., 2006. Detection of harmful cyanobacteria and their toxins by both PCR amplication and LC-MS during a bloom event. Toxicon, vol. 48, no. 3, p. 239-245.
3. BABICA, P., BLAHA, L. and MARSALEK, B., 2006. Exploring the natural role of microcystins-a review of effects on photoautotrophic organisms. Journal of Phycology, vol. 42, no. 1, p. 9-20.
4. BITTENCOURT-OLIVEIRA, MC., 2003. Detection of potencial microcystin-producing cyanobacteria in Brazilian reservoirs with a mcyB molecular marker. Harmful Algae, vol. 2, p. 51-60.
5. BITTENCOURT-OLIVEIRA, MC., KUJBIDA, P., CARDOZO, KHM., CARVALHO, VM., MOURA, AN., COLEPICOLO, P. and PINTO, E., 2005. A novel rhythm of microcystin biosynthesis is described in the cyanobacterium Microcystis panniformis Komárek et al. Biochemical and Biophysical Research Communications, vol. 326, no. 3, p. 687-694.
6. BITTENCOURT-OLIVEIRA, MC., OLIVEIRA, MC. and BOLCH, CJS., 2001. Genetic variability of Brazilian strains of the Microcystis aeruginosa complex Cyanobacteria/Cyanophyceae) using the phycocyanin intergenic spacer and flanking regions (cpcBA). Journal of Phycology, vol. 37, no. 5, p. 810-818.
7. BRASIL, 2004. Regulation MS n. 518/2004. Guidelines for drinking water quality. Official Law Reports, 26 Mar. 2004. Section I, 266 p.
8. DINGA, W., SHENA, HM., ZHUB, HG, LEA, BL. and ONGA, CN., 1999. Genotoxicity of microcystic cyanobacteria extract of water source in China. Mutation Research-Genetic Toxicology and Environmental Mutagenis, vol. 442, no. 2, p. 69-77.
9. DITTMANN, E. and BÖRNER, T., 2005. Genetic contributions to the risk assessment of microcystin in the environment. Toxicology and Applied Pharmacology, vol. 203, no. 3, p. 192-200.
10. FALCONER, IR. and HUMPAGE, AR., 1996. Tumor promotion by cyanobacterial toxins. Phycologia, vol. 35 (Supplement), p. 74-79.
11. FASTNER, J., ERHARD, M., CARMICHAEL, WW., SUN, F., RINEHART, KL., RONICKE, H. and CHORUS, I., 1999. Characterization and diversity of microcystins in natural blooms and strains of the genera Microcystis and Planktothrix from German freshwaters. Archiv fuer Hydrobiologie, vol. 145, no. 2, p. 147-163.
12. FELSENSTEIN, J., 1985. Confidence limits on phylogenies: an approach using the bootstrap. Evolution, vol. 39, no. 4, p. 783-791.
13. FRIAS, HV., MENDES, MA., CARDOZO, KHM., CARVALHO, VM., TOMAZELA, D., COLEPICOLO, P. and PINTO, E., 2006. Use of electrospray tandem mass spectrometry for identification of microcystins during a cyanobacterial bloom event. Biochemical and Biophysical Research Communications, vol. 344, no. 3, p. 741-746.
14. JOCHIMSEN, EM., CARMICHAEL, WW., AN, J., CARDO, DM., COOKSON, ST., HOLMES, CEM., ANTUNES, MB., FILHO, DAM., LYRA, TM., BARRETO, VST., AZEVEDO, SMFO. and JARVIS, WR., 1998. Liver failure and death after exposure to microcystin at a hemodialysis center in Brazil. New England Journal of Medicine, vol. 338, no. 13, p. 873-878.
15. KAEBERNICK, M., DITTMANN, E., BÖRNER, T. and NEILAN, BA., 2002. Multiple alternate transcripts direct the biosynthesis of microcystin, a cyanobacterial non-ribosomal peptide. Applied and Environmental Microbiology, vol. 68, no. 2, p. 449-455.
16. KAEBERNICK, M., NEILAN, BA., BÖRNER, T. and DITTMANN, E., 2000. Light and the transcriptional response of the microcystin biosynthesis gene cluster. Applied and Environmental Microbiology, vol. 66, no. 8, p. 3387-3392.
17. KAEBERNICK, M., ROHRLACK, T., CHRISTOFFERSEN, K. and NEILAN, BA., 2001. A spontaneous mutant of microcystin biosynthesis: genetic characterization and effect on Daphnia. Environmental Microbiology, vol. 3, no. 11, p. 669-679.
18. KARDINAAL, WEA., TONK, L., JANSE, I., HOL, S., SLOT, P., HUISMAN, J. and VISSER, PM., 2007. Competition for light between toxic and nontoxic strains of the harmful cyanobacterium Microcystis. Applied and Environmental Microbiology, vol. 73, no. 9, p. 2939-2946.
19. KURMAYER, R. and KUTZENBERGER, T., 2003. Application of real-time PCR for quantification of microcystin genotypes in a population of the toxic cyanobacterium Microcystis sp. Applied and Environmental Microbiology, vol. 69, no. 11, p. 6723-6730.
20. KURMAYER, R., CHRISTIANSEN, G., FASTNER, J. and BÖRNER, T., 2004. Abundance of active and inactive microcystin genotypes in populations of the toxic cyanobacterium Planktothrix spp. Environmental Microbiology, vol. 6, no. 8, p. 831-841.
21. KURMAYER, R., DITTMANN, E., FASTNER, J. and CHORUS, I., 2002. Diversity of microcystin genes within a population of the toxic cyanobacterium Microcystis spp. in Lake Wannsee (Berlin, Germany). Microbial Ecology, vol. 43, no.1, p. 107-118.
22. LOURENÇO, SO. and VIEIRA, AAH. 2004., Culture Collections of microalgae in Brazil: progress and constraints. Nova Hedwigia, vol. 79, no. 1-2, p. 149-173.
23. LUKAC, M. and AEGERTER, R., 1993. Influence of trace metals on growth and toxin production of Microcystis aeruginosa. Toxicon, vol. 31, no. 3, p. 293-305.
24. MATTHIENSEN, A., BEATTIE, KA., YUNES, JS., KAYA, K. and CODD, GA., 2000. [D-Leu(1)] microcystin-LR, from the cyanobacterium Microcystis RST 9501 and from a Microcystis bloom in the Patos Lagoon estuary, Brazil. Phytochemistry, vol. 55, no. 5, p. 383-387.
25. MIKALSEN, B., BOISON, G., SKULBERG, OM., FASTNER, J., DAVIES, W., GABRIELSEN, TM., RUDI, K. and JAKOBSEN, KS., 2003. Natural variation in the microcystin synthetase operon mcyABC and impact on microcystin production in Microcystis strains. Journal of Bacteriology, vol. 185, no. 9, p. 2774-2785.
26. NEILAN, BA., JACOBS, D. and GOODMAN, AE., 1995. Genetic diversity and phylogeny of toxic cyanobacteria determined by DNA polymorphism within the phycocyanin locus. Applied and Environmental Microbiology, vol. 61, no. 11, p. 3875-83.
27. NISHIWAKI-MATSUSHIMA, R., OHTA, T., NISHIWAKI, S., SUGANUMA, M., KOHYAMA, K., ISHIKAWA, T., CARMICHAEL, WW. and FUJIKI, H., 1992. Liver tumor promotion by cyanobacterial cyclic peptide toxin microcystin-LR. Journal of Cancer Research and Clinical Oncology, vol. 118, no. 6, p. 420-424.
28. NISHIZAWA, T., ASAYAMA, M., FUJII, K., HARADA, K-I. and SHIRAI, M., 1999. Genetic analysis of the peptide synthetase genes for a cyclic heptapeptide microcystin in Microcystis spp. Journal of Biochemistry, vol. 126, no. 3, p. 520-529.
29. NISHIZAWA, T., UEDA, A., ASAYAMA, M., FUJII, K., HARADA, K.-I., OCHI, K. and SHIRAI, M., 2000. Polyketide synthase gene coupled to the peptide synthetase module involved in the biosynthesis of the cyclic heptapeptide microcystin. Journal of Biochemistry, vol. 127, no. 5, p. 779-789.
30. OUELLETTE, AJA. and WILHELM, SW., 2003. Toxic cyanobacteria: the evolving molecular toolbox. Frontiers in Ecology and the Environment, vol. 1, no. 2, p. 359-366.
31. PAN, H., SONG, L., LIU, Y. and BÖRNER, T., 2002. Detection of hepatotoxic Microcystis strains by PCR with intact cells from both culture and environmental samples. Archives of Microbiology, vol. 178, no. 6, p. 421-427.
32. RIPPKA, R., DERUELLES, J., WATERBURY, JB., HERDMAN, M. and STANIER, RY., 1979. Generic assignments, strain histories and properties of pure cultures of cyanobacteria. Journal of General Microbiology, vol. 111, no. 1, p. 1-61.
33. SCHATZ, D., KEREN, Y., VARDI, A., SUKENIK, A., CARMELI, S., BÖRNER, T., DITTMANN, E. and KAPLAN, A., 2007. Towards clarification of the biological role of microcystins, a family of cyanobacterial toxins. Environmental Microbiology, vol. 9, no. 4, p. 965-970.
34. SWOFFORD, DL., 2000. PAUP* Phylogenetic analysis using parsimony (*and Other Methods). Version 4.0. Sunderland, MA: Sinauer Associates. 1 CD-ROM.
35. TILLETT, D., DITTMANN, E., ERHARD, M., VON DÖHREN, H., BÖRNER, T. and NEILAN, BA., 2000. Structural organization of microcystin biosynthesis in Microcystis aeruginosa PCC7806: an integrated peptide-polyketide synthetase system. Chemical Biology, vol. 7, no. 10, p. 753-764.
36. TILLETT, D., PARKER, DL. and NEILAN, BA., 2001. Detection of toxigenicity by a probe for the microcystin synthetase A gene (mcyA) of the cyanobacterial genus Microcystis: comparison of toxicities with 16S rRNA and phycocyanin operon (phycocyanin intergenic spacer) phylogenies. Applied and Environmental Microbiology, vol. 67, no. 6, p. 2810-2818.
37. UTKILEN, H. and GJØLME, N., 1992. Toxin production by Microcystis aeruginosa as a function of light in continuous cultures and its ecological significance. Applied and Environmental Microbiology, vol. 58, no. 4, p. 1321-1325.
38. VIA-ORDORIKA, L., FASTNER, J., KURMAYER, R., HISBERGUES, M., DITTMANN, E., KOMÁREK, J., ERHARD, M. and CHORUS, I., 2004. Distribution of microcystin-producing and non-microcystin-producing Microcystis sp. in European freshwater bodies: Detection of microcystins and microcystin genes in individual colonies. Systematic and Applied Microbiology, vol. 27, no. 5, p. 592-602.
39. WATANABE, MF. and OISHI, S., 1985. Effects of environmental factors on toxicity of a cyanobacterium (Microcystis aeruginosa) under culture conditions. Applied and Environmental Microbiology, vol. 49, no. 5, p. 1342-1344.
40. YOSHIDA, T., YUKI, Y., LEI, S., CHINEN, H., YOSHIDA, M., KONDO R. and HIROISHI, S., 2003. Quantitative detection of toxic strains of the cyanobacterial genus Microcystis by competitive PCR. Microbial and Environment, vol. 18, no. 1, p. 16-23.