Use of electrospray tandem mass spectrometry for identification of microcystins during a cyanobacterial bloom event

Biochemical and Biophysical Research Communications

Volumn 344, Issue 3, 2006, Pages 741-746

  Frias, Humberto Vieira ^a   Mendes, Maria Anita ^a   Cardozo, Karina Helena Morais ^a   Carvalho, Valdemir Melechco ^b   Tomazela, Daniela ^c   Colepicolo, Pio ^a   Pinto, Ernani ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b Fleury   (Brazil)

^c Waters Technologies do Brazil   (Brazil)

Author keywords

Billings reservoir; Bloom; ESI MS MS; Microcystin; Microcystis

Indexed keywords

CYANOGINOSIN; CYANOGINOSIN HRHR; CYANOGINOSIN LR; CYANOGINOSIN RR; HOMOARGININE; UNCLASSIFIED DRUG;

ARTICLE; CYANOBACTERIUM; CYANOGINOSIN YR; ELECTROSPRAY MASS SPECTROMETRY; EUTROPHICATION; MICROCYSTIS; NONHUMAN; PRIORITY JOURNAL; PURIFICATION; RESERVOIR; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY;

CYANOBACTERIA; ENVIRONMENTAL MONITORING; EUTROPHICATION; MICROCYSTINS; PEPTIDES, CYCLIC; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; WATER MICROBIOLOGY; WATER POLLUTANTS;

CYANOBACTERIA; MICROCYSTIS;

EID: 33646489311     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.03.199     Document Type: Article

References (24)

1. de Figueiredo D.R., Azeiteiro U.M., Esteves S.M., Goncalves F.J.M., and Pereira M.J. Microcystin-producing blooms-a serious global public health issue. Ecotoxicol. Environ. Saf. 59 (2004) 151-163
2. Babica P., Blaha L., and Marsalek B. Exploring the natural role of microcystins-a review of effects on photoautotrophic organisms. J. Phycol. 42 (2006) 9-20
3. Moore B.S. Biosynthesis of marine natural products: microorganisms (Part A). Nat. Prod. Rep. 22 (2005) 580-593
4. Bittencourt-Oliveira M.C., Kujbida P., Cardozo K.H.M., Carvalho V.M., Moura A.N., Colepicolo P., and Pinto E. A novel rhythm of microcystin biosynthesis is described in the cyanobacterium Microcystis panniformis Komarek et al. Biotech. Biophys. Res. Commun. 326 (2005) 687-694
5. Dahlmann J., Budakowski W.R., and Luckas B. Liquid chromatography-electrospray ionisation-mass spectrometry based method for the simultaneous determination of algal and cyanobacterial toxins in phytoplankton from marine waters and lakes followed by tentative structural elucidation of microcystins. J. Chromatogr. A 994 (2003) 45-57
6. Yuan M., Namikoshi M., Otsuki A., Rinehart K.L., Sivonen K., and Watanabe M.F. Low-energy collisionally activated decomposition and structural characterization of cyclic heptapeptide microcystins by electrospray ionization mass spectrometry. J. Mass Spectrom. 34 (1999) 33-43
7. Gulledge B.M., Aggen J.B., Huang H.B., Nairn A.C., and Chamberlin A.R. The microcystins and nodularins: cyclic polypeptide inhibitors of PP1 and PP2A. Curr. Med. Chem. 9 (2002) 1991-2003
8. Codd G.A., Morrison L.F., and Metcalf J.S. Cyanobacterial toxins: risk management for health protection. Toxicol. Appl. Pharmacol. 203 (2005) 264-272
9. Barford D. Molecular mechanisms of the protein serine threonine phosphatases. Trends Biochem. Sci. 21 (1996) 407-412
10. Runnegar M., Berndt N., Kong S.M., Lee E.Y.C., and Zhang L.F. In-vivo and in-vitro binding of microcystin to protein phosphatase-1 and phosphatase-2A. Biochem. Biophys. Res. Commun. 216 (1995) 162-169
11. Chen T., Wang Q.S., Cui J., Yang W., Shi Q., Hua Z.C., Ji J.G., and Shen P.P. Induction of apoptosis in mouse liver by microcystin-LR-a combined transcriptomic, proteomic, and simulation strategy. Mol. Cell. Proteomics 4 (2005) 958-974
12. Kujbida P., Hatanaka E., Campa A., Colepicolo P., and Pinto E. Effects of microcystins on human polymorphonuclear leukocytes. Biochem. Biophys. Res. Commun. 341 (2006) 273-277
13. Chorus I., and Bartram J. Toxic Cyanobacteria in Water-A Guide to their Public Health Consequences, Monitoring and Management (2003), Spon Press, London
14. Hawkins P.R., Novic S., Cox P., Neilan B.A., Burns B.P., Shaw G., Wickramasinghe W., Peerapornpisal Y., Ruangyuttikarn W., Itayama T., Saitou T., Mizuochi M., and Inamori Y. A review of analytical methods for assessing the public health risk from microcystin in the aquatic environment. J. Water Supply Res. Technol.-Aqua. 54 (2005) 509-518
15. Kaya K., Sano T., Inoue H., and Takagi H. Selective determination of total normal microcystin by colorimetry, LC/UV detection and/or LC/MS. Anal. Chim. Acta 450 (2001) 73-80
16. Meriluoto J. Chromatography of microcystins. Anal. Chim. Acta 352 (1997) 277-298
17. Hummert C., Reichelt M., Weiss J., Liebert H.P., and Luckas B. Identification of microcystins in cyanobacteria from the Bleiloch former drinking-water reservoir (Thuringia, Germany). Chemosphere 44 (2001) 1581-1588
18. Kubwabo C., Vais N., and Benoit F.M. Characterization of microcystins using in-source collision-induced dissociation. Rapid Commun. Mass Spectrom. 19 (2005) 597-604
19. Hill J.J., Callaghan D.A., Ding W., Kelly J.F., and Chakravarthy B.R. Identification of okadaic acid-induced phosphorylation events by a mass spectrometry approach. Biochem. Biophys. Res. Commun. 342 (2006) 791-799
20. Spoof L., Vesterkvist P., Lindholm T., and Meriluoto J. Screening for cyanobacterial hepatotoxins, microcystins and nodularin in environmental water samples by reversed-phase liquid chromatography-electrospray ionisation mass spectrometry. J. Chromatogr. A 1020 (2003) 105-119
21. Diehnelt C.W., Dugan N.R., Peterman S.M., and Budde W.L. Identification of microcystin toxins from a strain of Microcystis aeruginosa by liquid chromatography introduction into a hybrid linear ion trap-fourier transform ion cyclotron resonance mass spectrometer. Anal. Chem. 78 (2006) 501-512
22. Maizels M., and Budde W.L. A LC/MS method for the determination of cyanobacteria toxins in water. Anal. Chem. 76 (2004) 1342-1351
23. Diehnelt C.W., Peterman S.M., and Budde W.L. Liquid chromatography-tandem mass spectrometry and accurate m/z measurements of cyclic peptide cyanobacteria toxins rac. Trends Anal. Chem. 24 (2005) 622-634
24. Regulation MS N. 518/2004: Guidelines for Drinking Water Quality, 'Official Law Reports,' 26/March/2004, section I, 266.