RUNX3 maintains the mesenchymal phenotype after termination of the notch signal

Journal of Biological Chemistry

Volumn 286, Issue 13, 2011, Pages 11803-11813

  Fu, YangXin ^a   Chang, Alex Chia Yu ^a   Fournier, Michèle ^a   Chang, Linda ^a   Niessen, Kyle ^a   Karsan, Aly ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ECTOPIC EXPRESSIONS; HEART DEVELOPMENT; IN-VIVO; INITIAL INDUCTION; MESENCHYMAL CELLS; TRANSCRIPTIONAL REPRESSORS;

TRANSCRIPTION FACTORS;

HEART;

CBF1 SUPPRESSOR OF HAIRLESS LAG PROTEIN; DNA BINDING PROTEIN; NOTCH RECEPTOR; TRANSCRIPTION FACTOR RUNX3; TRANSCRIPTION FACTOR SLUG; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR CANAL; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; ENDOCARDIAL CUSHION; ENDOTHELIUM CELL; HALF LIFE TIME; HEART DEVELOPMENT; HUMAN; HUMAN CELL; IN VIVO STUDY; MESENCHYME CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

CELL LINE; CORE BINDING FACTOR ALPHA 3 SUBUNIT; EMBRYO, MAMMALIAN; ENDOTHELIUM; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HALF-LIFE; HEART; HUMANS; MESODERM; ORGANOGENESIS; PROMOTER REGIONS, GENETIC; RECEPTORS, NOTCH; TRANSCRIPTION FACTORS;

EID: 79953208666     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.222331     Document Type: Article

References (46)

1. Armstrong, E. J., and Bischoff, J. (2004) Circ. Res. 95, 459-470
2. Zeisberg, E. M., Tarnavski, O., Zeisberg, M., Dorfman, A. L., McMullen, J. R., Gustafsson, E., Chandraker, A., Yuan, X., Pu, W. T., Roberts, A. B., Neilson, E. G., Sayegh, M. H., Izumo, S., and Kalluri, R. (2007) Nat. Med. 13, 952-961
3. Zeisberg, E. M., Potenta, S., Xie, L., Zeisberg, M., and Kalluri, R. (2007) Cancer Res. 67, 10123-10128
4. Artavanis-Tsakonas, S., Rand, M. D., and Lake, R. J. (1999) Science 284, 770-776
5. Noseda, M., McLean, G., Niessen, K., Chang, L., Pollet, I., Montpetit, R., Shahidi, R., Dorovini-Zis, K., Li, L., Beckstead, B., Durand, R. E., Hoodless, P. A., and Karsan, A. (2004) Circ. Res. 94, 910-917
6. Timmerman, L. A., Grego-Bessa, J., Raya, A., Bertrán, E., Pérez-Pomares, J. M., Díez, J., Aranda, S., Palomo, S., McCormick, F., Izpisúa-Belmonte, J. C., and de la Pompa, J. L. (2004) Genes Dev. 18, 99-115
7. High, F. A., and Epstein, J. A. (2008) Nat. Rev. Genet 9, 49-61
8. Niessen, K., and Karsan, A. (2008) Circ. Res. 102, 1169-1181
9. Nam, Y., Sliz, P., Song, L., Aster, J. C., and Blacklow, S. C. (2006) Cell 124, 973-983
10. Wu, L., Sun, T., Kobayashi, K., Gao, P., and Griffin, J. D. (2002) Mol. Cell Biol. 22, 7688-7700
11. Iso, T., Kedes, L., and Hamamori, Y. (2003) J. Cell Physiol. 194, 237-255
12. Fischer, A., Steidl, C., Wagner, T. U., Lang, E., Jakob, P. M., Friedl, P., Knobeloch, K. P., and Gessler, M. (2007) Circ. Res. 100, 856-863
13. Fischer, A., Schumacher, N., Maier, M., Sendtner, M., and Gessler, M. (2004) Genes Dev. 18, 901-911
14. Donovan, J., Kordylewska, A., Jan, Y. N., and Utset, M. F. (2002) Curr. Biol. 12, 1605-1610
15. Niessen, K., Fu, Y., Chang, L., Hoodless, P. A., McFadden, D., and Karsan, A. (2008) J. Cell Biol. 182, 315-325
16. Del Monte, G., Grego-Bessa, J., González-Rajal, A., Bolós, V., and De La Pompa, J. L. (2007) Dev. Dyn. 236, 2594-2614
17. Ito, Y. (2004) Oncogene 23, 4198-4208
18. Ito, Y. (2008) Adv. Cancer Res. 99, 33-76
19. Blyth, K., Cameron, E. R., and Neil, J. C. (2005) Nat. Rev. Cancer 5, 376-387
20. Burns, C. E., Traver, D., Mayhall, E., Shepard, J. L., and Zon, L. I. (2005) Genes Dev. 19, 2331-2342
21. Garg, V., Muth, A. N., Ransom, J. F., Schluterman, M. K., Barnes, R., King, I. N., Grossfeld, P. D., and Srivastava, D. (2005) Nature 437, 270-274
22. Fu, Y., Chang, A., Chang, L., Niessen, K., Eapen, S., Setiadi, A., and Karsan, A. (2009) J. Biol. Chem. 284, 19452-19462
23. Leong, K. G., Niessen, K., Kulic, I., Raouf, A., Eaves, C., Pollet, I., and Karsan, A. (2007) J. Exp. Med. 204, 2935-2948
24. Noseda, M., Fu, Y., Niessen, K., Wong, F., Chang, L., McLean, G., and Karsan, A. (2006) Circ. Res. 98, 1468-1470
25. Wederell, E. D., Bilenky, M., Cullum, R., Thiessen, N., Dagpinar, M., Delaney, A., Varhol, R., Zhao, Y., Zeng, T., Bernier, B., Ingham, M., Hirst, M., Robertson, G., Marra, M. A., Jones, S., and Hoodless, P. A. (2008) Nucleic Acids Res. 36, 4549-4564
26. Sarao, R., and Dumont, D. J. (1998) Transgenic Res. 7, 421-427
27. Nakagawa, M., Ichikawa, M., Kumano, K., Goyama, S., Kawazu, M., Asai, T., Ogawa, S., Kurokawa, M., and Chiba, S. (2006) Blood 108, 3329-3334
28. MacKenzie, F., Duriez, P., Larrivée, B., Chang, L., Pollet, I., Wong, F., Yip, C., and Karsan, A. (2004) Blood 104, 1760-1768
29. High, F. A., Zhang, M., Proweller, A., Tu, L., Parmacek, M. S., Pear, W. S., and Epstein, J. A. (2007) J. Clin. Invest. 117, 353-363
30. Joutel, A., Andreux, F., Gaulis, S., Domenga, V., Cecillon, M., Battail, N., Piga, N., Chapon, F., Godfrain, C., and Tournier-Lasserve, E. (2000) J. Clin. Invest. 105, 597-605
31. Oka, C., Nakano, T., Wakeham, A., de la Pompa, J. L., Mori, C., Sakai, T., Okazaki, S., Kawaichi, M., Shiota, K., Mak, T. W., and Honjo, T. (1995) Development 121, 3291-3301
32. Brennan, K., and Gardner, P. (2002) Bioessays 24, 405-410
33. Oberg, C., Li, J., Pauley, A., Wolf, E., Gurney, M., and Lendahl, U. (2001) J. Biol. Chem. 276, 35847-35853
34. Wu, G., Lyapina, S., Das, I., Li, J., Gurney, M., Pauley, A., Chui, I., Deshaies, R. J., and Kitajewski, J. (2001) Mol. Cell Biol. 21, 7403-7415
35. Li, L., Krantz, I. D., Deng, Y., Genin, A., Banta, A. B., Collins, C. C., Qi, M., Trask, B. J., Kuo, W. L., Cochran, J., Costa, T., Pierpont, M. E., Rand, E. B., Piccoli, D. A., Hood, L., and Spinner, N. B. (1997) Nat. Genet. 16, 243-251
36. Swiatek, P. J., Lindsell, C. E., del Amo, F. F., Weinmaster, G., and Gridley, T. (1994) Genes Dev. 8, 707-719
37. Van de Walle, I., De Smet, G., De Smedt, M., Vandekerckhove, B., Leclercq, G., Plum, J., and Taghon, T. (2009) Blood 113, 2988-2998
38. Hilton, M. J., Tu, X., Wu, X., Bai, S., Zhao, H., Kobayashi, T., Kronenberg, H. M., Teitelbaum, S. L., Ross, F. P., Kopan, R., and Long, F. (2008) Nat. Med. 14, 306-314
39. Engin, F., Yao, Z., Yang, T., Zhou, G., Bertin, T., Jiang, M. M., Chen, Y., Wang, L., Zheng, H., Sutton, R. E., Boyce, B. F., and Lee, B. (2008) Nat. Med. 14, 299-305
40. Nigam, V., and Srivastava, D. (2009) J. Mol. Cell Cardiol. 47, 828-834
41. Mailhos, C., Modlich, U., Lewis, J., Harris, A., Bicknell, R., and Ish-Horowicz, D. (2001) Differentiation 69, 135-144
42. Uyttendaele, H., Marazzi, G., Wu, G., Yan, Q., Sassoon, D., and Kitajewski, J. (1996) Development 122, 2251-2259
43. Gao, J., Chen, Y., Wu, K. C., Liu, J., Zhao, Y. Q., Pan, Y. L., Du, R., Zheng, G. R., Xiong, Y. M., Xu, H. L., and Fan, D. M. (2010) Exp. Cell Res. 316, 149-157
44. Thompson, B. J., Buonamici, S., Sulis, M. L., Palomero, T., Vilimas, T., Basso, G., Ferrando, A., and Aifantis, I. (2007) J. Exp. Med. 204, 1825-1835
45. Tsunematsu, R., Nakayama, K., Oike, Y., Nishiyama, M., Ishida, N., Hatakeyama, S., Bessho, Y., Kageyama, R., Suda, T., and Nakayama, K. I. (2004) J. Biol. Chem. 279, 9417-9423
46. O'Neil, J., Grim, J., Strack, P., Rao, S., Tibbitts, D., Winter, C., Hardwick, J., Welcker, M., Meijerink, J. P., Pieters, R., Draetta, G., Sears, R., Clurman, B. E., and Look, A. T. (2007) J. Exp. Med. 204, 1813-1824