Quantitation of serum IgE by using chimeras of human IgE receptor and avian immunoglobulin domains

Analytical Biochemistry

Volumn 412, Issue 2, 2011, Pages 134-140

  Braren, Ingke ^a   Greunke, Kerstin ^a   Pilette, Charles ^b   Mempel, Martin ^c   Grunwald, Thomas ^a   Bredehorst, Reinhard ^d   Ring, Johannes ^e   Spillner, Edzard ^d   Ollert, Markus ^e  

^a PLS Design   (Germany)

^b CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d UNIVERSITY OF HAMBURG   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Anti IgE; Complex formation; FcRI; IgE; Omalizumab

Indexed keywords

ENZYME IMMOBILIZATION;

ANTI-IGE; COMPLEX FORMATIONS; ENZYME LINKED IMMUNOSORBENT ASSAY; FCRI; HIGH-AFFINITY IGE RECEPTORS; INTERFERENCE PHENOMENA; OMALIZUMAB; SOLUBLE DERIVATIVES;

PATIENT TREATMENT;

BLOCKING ANTIBODY; FC EPSILON RI ALPHA PROTEIN; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN E RECEPTOR; IMMUNOGLOBULIN Y; LIGAND; OMALIZUMAB; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ALLERGIC RHINITIS; ANALYTIC METHOD; ANTIBODY AFFINITY; ARTICLE; BIOLOGICAL MONITORING; CELL LINE; CELL STRAIN HEK293; CHIMERA; CLINICAL ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ECZEMA; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOBLOTTING; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOGLOBULIN PRODUCTION; IMMUNOREACTIVITY; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; QUANTITATIVE ANALYSIS; RHINOCONJUNCTIVITIS;

AVES;

EID: 79953198570     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2010.12.013     Document Type: Article

References (55)

1. F.D. Finkelman, and D. Vercelli Advances in asthma, allergy mechanisms, and genetics in 2006 J. Allergy Clin. Immunol. 120 2007 2006 544 550 (Pubitemid 47320758)
2. H.J. Gould, and B.J. Sutton IgE in allergy and asthma today Nat. Rev. Immunol. 8 2008 205 217 (Pubitemid 351323292)
3. S. Kraft, and J.P. Kinet New developments in FcRI regulation, function, and inhibition Nat. Rev. Immunol. 7 2007 365 378 (Pubitemid 46674486)
4. J.P. Kinet The high-affinity IgE receptor (FcRI): from physiology to pathology Annu. Rev. Immunol. 17 1999 931 972
5. M. Iikura, M. Yamaguchi, K. Hirai, M. Miyamasu, H. Yamada, T. Nakajima, T. Fujisawa, C. Ra, Y. Morita, and K. Yamamoto Regulation of surface FcRI expression on human eosinophils by IL-4 and IgE Intl. Arch. Allergy Immunol. 124 2001 470 477 (Pubitemid 32429690)
6. T.W. Chang The pharmacological basis of anti-IgE therapy Nat. Biotechnol. 18 2000 157 162 (Pubitemid 30091174)
7. Z. Peng Vaccines targeting IgE in the treatment of asthma and allergy Hum. Vaccin. 5 2009 302 309
8. L. Presta, R. Shields, L. O'Connell, S. Lahr, J. Porter, C. Gorman, and P. Jardieu The binding site on human immunoglobulin E for its high affinity receptor J. Biol. Chem. 269 1994 26368 26373 (Pubitemid 24328457)
9. L.G. Presta, S.J. Lahr, R.L. Shields, J.P. Porter, C.M. Gorman, B.M. Fendly, and P.M. Jardieu Humanization of an antibody directed against IgE J. Immunol. 151 1993 2623 2632 (Pubitemid 23264514)
10. R.L. Shields, W.R. Whether, K. Zioncheck, L. O'Connell, B. Fendly, L.G. Presta, D. Thomas, R. Saban, and P. Jardieu Inhibition of allergic reactions with antibodies to IgE Intl. Arch. Allergy Immunol. 107 1995 308 312
11. D.W. MacGlashan Jr., B.S. Bochner, D.C. Adelman, P.M. Jardieu, A. Togias, J. McKenzie-White, S.A. Sterbinsky, R.G. Hamilton, and L.M. Lichtenstein Down-regulation of FcÎμRI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody J. Immunol. 158 1997 1438 1445 (Pubitemid 127469971)
12. G. Gomez, S. Jogie-Brahim, M. Shima, and L.B. Schwartz Omalizumab reverses the phenotypic and functional effects of IgE-enhanced FcRI on human skin mast cells J. Immunol. 179 2007 1353 1361
13. S.T. Holgate, R. Djukanovic, T. Casale, and J. Bousquet Anti-immunoglobulin E treatment with omalizumab in allergic diseases: an update on anti-inflammatory activity and clinical efficacy Clin. Exp. Allergy 35 2005 408 416 (Pubitemid 40577231)
14. R.J. van Neerven, E.F. Knol, A. Ejrnaes, and P.A. Würtzen IgE-mediated allergen presentation and blocking antibodies: regulation of T-cell activation in allergy Intl. Arch. Allergy Immunol. 141 2006 119 129 (Pubitemid 44413287)
15. D.W. MacGlashan Jr., S.P. Peters, J. Warner, and L.M. Lichtenstein Characteristics of human basophil sulfidopeptide leukotriene release: releasability defined as the ability of the basophil to respond to dimeric cross-links J. Immunol. 136 1986 2231 2239 (Pubitemid 16122312)
16. Genentech and Novartis Pharmaceuticals, Pulmonary-Allergy Drugs Advisory Committee meeting, 15 May 2003, < http://www.fda.gov/ohrms/dockets/ac/03/ briefing/3952B1-01-Genentech-Xolair.pdf />.
17. R.G. Hamilton, G.V. Marcotte, and S.S. Saini Immunological methods for quantifying free and total serum IgE levels in allergy patients receiving omalizumab (Xolair) therapy J. Immunol. Methods 303 2005 81 91 (Pubitemid 41169948)
18. S. Sun, W. Mo, Y. Ji, and S. Liu Preparation and mass spectrometric study of egg yolk antibody (IgY) against rabies virus Rapid Commun. Mass Spectrom. 15 2001 708 712 (Pubitemid 32428485)
19. B. Belloni, M. Ziai, A. Lim, B. Lemercier, M. Sbornik, S. Weidinger, C. Andres, C. Schnopp, J. Ring, R. Hein, M. Ollert, and M. Mempel Low-dose anti-IgE therapy in patients with atopic eczema with high serum IgE levels J. Allergy Clin. Immunol. 120 2007 1223 1225 (Pubitemid 350047479)
20. K. Greunke, E. Spillner, I. Braren, H. Seismann, S. Kainz, U. Hahn, T. Grunwald, and R. Bredehorst Bivalent monoclonal IgY antibody formats by conversion of recombinant antibody fragments J. Biotechnol. 124 2006 446 456
21. I. Braren, S. Blank, H. Seismann, S. Deckers, M. Ollert, T. Grunwald, and E. Spillner Generation of human monoclonal allergen-specific IgE and IgG antibodies from synthetic antibody libraries Clin. Chem. 53 2007 837 844 (Pubitemid 46744238)
22. I. Braren, K. Greunke, O. Umland, S. Deckers, R. Bredehorst, and E. Spillner Comparative expression of different antibody formats in mammalian cells and Pichia pastoris Biotechnol. Appl. Biochem. 47 2007 205 214 (Pubitemid 47218255)
23. F.M. Ausubel, R. Brent, R.E. Kingston, D.D. Moore, J.G. Seidman, J.A. Smith, and K. Struhl Current Protocols in Molecular Biology 1994 Greene Publishing and Wiley-Interscience
24. R.G. Slavin, C. Ferioli, S.J. Tannenbaum, C. Martin, M. Blogg, and P.J. Lowe Asthma symptom re-emergence after omalizumab withdrawal correlates well with increasing IgE and decreasing pharmacokinetic concentrations J. Allergy Clin. Immunol. 123 2009 107 113
25. J. Corne, R. Djukanovic, L. Thomas, J. Warner, L. Botta, B. Grandordy, D. Gygax, C. Heusser, F. Patalano, W. Richardson, E. Kilchherr, T. Staehelin, F. Davis, W. Gordon, L. Sun, R. Liou, G. Wang, T.W. Chang, and S. Holgate The effect of intravenous administration of a chimeric anti-IgE antibody on serum IgE levels in atopic subjects: efficacy, safety, and pharmacokinetics J. Clin. Invest. 99 1997 879 887 (Pubitemid 27123624)
26. J. Liu, P. Lester, S. Builder, and S.J. Shire Characterization of complex formation by humanized anti-IgE monoclonal antibody and monoclonal human IgE Biochemistry 34 1995 10474 10482
27. F.M. Davis, L.A. Gossett, K.L. Pinkston, R.S. Liou, L.K. Sun, Y.W. Kim, N.T. Chang, T.W. Chang, K. Wagner, and J. Bews Can anti-IgE be used to treat allergy? Springer Semin. Immunopathol. 15 1993 51 73 (Pubitemid 23175440)
28. B. Demeule, S.J. Shire, and J. Liu A therapeutic antibody and its antigen form different complexes in serum than in phosphate-buffered saline: a study by analytical ultracentrifugation Anal. Biochem. 388 2009 279 287
29. R.G. Hamilton Accuracy of US Food and Drug Administration-cleared IgE antibody assays in the presence of anti-IgE (omalizumab) J. Allergy Clin. Immunol. 117 2006 759 766
30. rhuMAb-E25 Study Group Treatment of allergic asthma with monoclonal anti-IgE antibody N. Engl. J. Med. 341 1999 1966 1973
31. J. Liu, J. Ruppel, and S.J. Shire Interaction of human IgE with soluble forms of IgE high affinity receptors Pharm. Res. 14 1997 1388 1393 (Pubitemid 27481069)
32. L. Miller, U. Blank, H. Metzger, and J.P. Kinet Expression of high-affinity binding of human immunoglobulin E by transfected cells Science 244 1989 334 337 (Pubitemid 19117868)
33. T. Ishizaka, A.M. Dvorak, D.H. Conrad, J.R. Niebyl, J.P. Marquette, and K. Ishizaka Morphologic and immunologic characterization of human basophils developed in cultures of cord blood mononuclear cells J. Immunol. 134 1985 532 540 (Pubitemid 15191548)
34. U. Blank, C.S. Ra, and J.P. Kinet Characterization of truncated α-chain products from human, rat, and mouse high affinity receptor for immunoglobulin E J. Biol. Chem. 266 1991 2639 2646 (Pubitemid 21909110)
35. T.B. Casale, I.L. Bernstein, W.W. Busse, C.F. LaForce, D.G. Tinkelman, R.R. Stoltz, R.J. Dockhorn, J. Reimann, J.Q. Su, R.B. Fick Jr., and D.C. Adelman Use of an anti-IgE humanized monoclonal antibody in ragweed-induced allergic rhinitis J. Allergy Clin. Immunol. 100 1997 110 121 (Pubitemid 27328539)
36. S.D. Mendonsa, and M.T. Bowser In vitro selection of high-affinity DNA ligands for human IgE using capillary electrophoresis Anal. Chem. 76 2004 5387 5392 (Pubitemid 39249420)
37. M. Bencurova, W. Hemmer, M. Focke-Tejkl, I.B. Wilson, and F. Altmann Specificity of IgG and IgE antibodies against plant and insect glycoprotein glycans determined with artificial glycoforms of human transferrin Glycobiology 14 2004 457 466 (Pubitemid 38744927)
38. R.C. Aalberse, J. Akkerdaas, and R. van Ree Cross-reactivity of IgE antibodies to allergens Allergy 56 2001 478 490 (Pubitemid 32521427)
39. K. Hancock, S. Narang, S. Pattabhi, M.L. Yushak, A. Khan, S.C. Lin, R. Plemons, M.J. Betenbaugh, and V.C. Tsang False positive reactivity of recombinant, diagnostic glycoproteins produced in High Five insect cells: effect of glycosylation J. Immunol. Methods 330 2008 130 136
40. H. Seismann, S. Blank, I. Braren, K. Greunke, L. Cifuentes, T. Grunwald, R. Bredehorst, M. Ollert, and E. Spillner Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of α-1, 3-core fucosylation Mol. Immunol. 47 2009 779 808
41. T.P. Vikinge, A. Askendal, B. Liedberg, T. Lindahl, and P. Tengvall Immobilized chicken antibodies improve the detection of serum antigens with surface plasmon resonance (SPR) Biosens. Bioelectron. 13 1998 1257 1262 (Pubitemid 29003004)
42. D. Carlander, and A. Larsson Avian antibodies can eliminate interference due to complement activation in ELISA Ups. J. Med. Sci. 106 2001 189 195 (Pubitemid 33643802)
43. L.M. Boscato, and M.C. Stuart Heterophilic antibodies: a problem for all immunoassays Clin. Chem. 34 1988 27 33 (Pubitemid 18039404)
44. K. Greunke, I. Braren, I. Alpers, S. Blank, J. Sodenkamp, R. Bredehorst, and E. Spillner Recombinant IgY for improvement of immunoglobulin-based analytical applications Clin. Biochem. 41 2008 1237 1244
45. P.J. Lowe, S. Tannenbaum, A. Gautier, and P. Jimenez Relationship between omalizumab pharmacokinetics, IgE pharmacodynamics, and symptoms in patients with severe persistent allergic (IgE-mediated) asthma Br. J. Clin. Pharmacol. 68 2009 61 76
46. U. Wahn, C. Martin, P. Freeman, M. Blogg, and P. Jimenez Relationship between pretreatment specific IgE and the response to omalizumab therapy Allergy 64 2009 1780 1787
47. Omalizumab Rhinitis Study Group Specific IgE serum concentration is associated with symptom severity in children with seasonal allergic rhinitis Allergy 63 2008 1339 1344
48. S.G. Johansson, A. Nopp, H. Oman, J. Ankerst, L.O. Cardell, R. Gronneberg, H. Matsols, S. Rudblad, V. Strand, and G. Stalenheim The size of the disease relevant IgE antibody fraction in relation to "total-IgE" predicts the efficacy of anti-IgE (Xolair) treatment Allergy 64 2009 1472 1477
49. G. Hochhaus, L. Brookman, H. Fox, C. Johnson, J. Matthews, S. Ren, and Y. Deniz Pharmacodynamics of omalizumab: implications for optimised dosing strategies and clinical efficacy in the treatment of allergic asthma Curr. Med. Res. Opin. 19 2003 491 498 (Pubitemid 37122042)
50. E. Adelroth, S. Rak, T. Haahtela, G. Aasand, L. Rosenhall, O. Zetterstrom, A. Byrne, K. Champain, J. Thirlwell, G.D. Cioppa, and T. Sandström Recombinant humanized mAb-E25, an anti-IgE mAb, in birch pollen-induced seasonal allergic rhinitis J. Allergy Clin. Immunol. 106 2000 253 259 (Pubitemid 30644998)
51. J. Ankerst, A. Nopp, S.G. Johansson, J. Adedoyin, and H. Oman Xolair is effective in allergics with a low serum IgE level Intl. Arch. Allergy Immunol. 152 2010 71 74
52. A. Lim, S. Luderschmidt, A. Weidinger, C. Schnopp, J. Ring, R. Hein, M. Ollert, and M. Mempel The IgE repertoire in PBMCs of atopic patients is characterized by individual rearrangements without variable region of the heavy immunoglobulin chain bias J. Allergy Clin. Immunol. 120 2007 696 706 (Pubitemid 47334838)
53. S.S. Saini, D.W. MacGlashan, S.A. Sterbinsky, A. Togias, D.C. Adelman, L.M. Lichtenstein, and B.S. Bochner Down-regulation of human basophil IgE and FCRIα surface densities and mediator release by anti-IgE infusions is reversible in vitro and in vivo J. Immunol. 162 1999 5624 5630 (Pubitemid 29307177)
54. J. Corren, G. Shapiro, J. Reimann, Y. Deniz, D. Wong, D. Adelman, and A. Togias Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy J. Allergy Clin. Immunol. 121 2008 506 511 (Pubitemid 351215181)
55. S. Ogino, T. Nagakura, K. Okubo, N. Sato, M. Takahashi, and T. Ishikawa Re-treatment with omalizumab at one year interval for Japanese cedar pollen-induced seasonal allergic rhinitis is effective and well tolerated Intl. Arch. Allergy Immunol. 149 2009 239 245