-
1
-
-
0032768327
-
Single cell gel electrophoresis: Detection of DNA damage at different levels of sensitivity
-
Angelis, K.J., Dusinska, M., and Collins, A.R. 1999. Single cell gel electrophoresis: Detection of DNA damage at different levels of sensitivity. Electrophoresis 20:2133-2138.
-
(1999)
Electrophoresis
, vol.20
, pp. 2133-2138
-
-
Angelis, K.J.1
Dusinska, M.2
Collins, A.R.3
-
2
-
-
0035912756
-
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
-
Blaisdell, J.O. and Wallace, S. 2001. Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 98:7426-7430.
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7426-7430
-
-
Blaisdell, J.O.1
Wallace, S.2
-
3
-
-
0030917436
-
Reactivity of human apurinic/apyrimidinic endonuclease and Escherichia coli exonuclease III with bistranded abasic sites in DNA
-
Chaudhry, M.A. and Weinfeld, M. 1997. Reactivity of human apurinic/apyrimidinic endonuclease and Escherichia coli exonuclease III with bistranded abasic sites in DNA. J. Biol. Chem. 272:15650-15655.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 15650-15655
-
-
Chaudhry, M.A.1
Weinfeld, M.2
-
4
-
-
8544283254
-
The comet assay for DNA damage and repair: Principles, applications and limitations
-
Collins, A.R. 2004. The comet assay for DNA damage and repair: Principles, applications and limitations. Mol. Biotechnol. 26:249-261.
-
(2004)
Mol. Biotechnol.
, vol.26
, pp. 249-261
-
-
Collins, A.R.1
-
5
-
-
35748950964
-
An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli
-
Cunniffe, S.M., Lomax, M.E., and O'Neill, P. 2007. An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli. DNA Repair 6:1839-1849.
-
(2007)
DNA Repair
, vol.6
, pp. 1839-1849
-
-
Cunniffe, S.M.1
Lomax, M.E.2
O'Neill, P.3
-
6
-
-
0037080182
-
Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease
-
David-Cordonnier, M.H., Cunniffe, S.M.T., Hickson, I.D., and O'Neill, P. 2002. Efficiency of incision of an AP site within clustered DNA damage by the major human AP endonuclease. Biochemistry 41:634-642.
-
(2002)
Biochemistry
, vol.41
, pp. 634-642
-
-
David-Cordonnier, M.H.1
Cunniffe, S.M.T.2
Hickson, I.D.3
O'Neill, P.4
-
7
-
-
33645136996
-
Minor contribution of direct ionization to DNA base damage induced by heavy ions
-
Douki, T., Ravanat, J.L., Pouget, J.P., Testard, I., and Cadet, J. 2006. Minor contribution of direct ionization to DNA base damage induced by heavy ions. Int. J. Radiat. Biol. 82:119-127.
-
(2006)
Int. J. Radiat. Biol.
, vol.82
, pp. 119-127
-
-
Douki, T.1
Ravanat, J.L.2
Pouget, J.P.3
Testard, I.4
Cadet, J.5
-
8
-
-
13744259832
-
Processingof acomplex multiply damaged DNA site by human cell extracts and purified repair proteins
-
Eot-Houllier, G., Eon-Marchais, S., Gasparutto, D., and Sage,E.2005. Processingof acomplex multiply damaged DNA site by human cell extracts and purified repair proteins. Nucleic Acids Res. 33:260-271.
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 260-271
-
-
Eot-Houllier, G.1
Eon-Marchais, S.2
Gasparutto, D.3
Sage, E.4
-
9
-
-
38849134202
-
Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and non-malignant MCF-10A cells
-
Francisco, D.C., Peddi, P., Hair, J.M., Flood, B.A., Cecil, A.M., Kalogerinis, P.T., Sigounas, G., and Georgakilas, A.G. 2008. Induction and processing of complex DNA damage in human breast cancer cells MCF-7 and non-malignant MCF-10A cells. Free Radic. Biol. Med. 44:558-569.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 558-569
-
-
Francisco, D.C.1
Peddi, P.2
Hair, J.M.3
Flood, B.A.4
Cecil, A.M.5
Kalogerinis, P.T.6
Sigounas, G.7
Georgakilas, A.G.8
-
10
-
-
44449148691
-
Oxidative stress, DNA methylation and carcinogenesis
-
Franco, R., Schoneveld, O., Georgakilas, A.G., and Panayiotidis, M.I. 2008. Oxidative stress, DNA methylation and carcinogenesis. Cancer Lett. 266:6-12.
-
(2008)
Cancer Lett
, vol.266
, pp. 6-12
-
-
Franco, R.1
Schoneveld, O.2
Georgakilas, A.G.3
Panayiotidis, M.I.4
-
11
-
-
37149027578
-
Processing of DNA damage clusters in human cells: Current status of knowledge
-
Georgakilas, A.G. 2008. Processing of DNA damage clusters in human cells: Current status of knowledge. Mol. Biosyst. 4:30-35.
-
(2008)
Mol. Biosyst.
, vol.4
, pp. 30-35
-
-
Georgakilas, A.G.1
-
12
-
-
0036639367
-
High efficiency detection of bistranded abasic clusters in γ-irradiated DNA by putrescine
-
Georgakilas, A.G., Bennett, P.V., and Sutherland, B.M. 2002. High efficiency detection of bistranded abasic clusters in γ-irradiated DNA by putrescine. Nucleic Acids Res. 30:2800-2808.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 2800-2808
-
-
Georgakilas, A.G.1
Bennett, P.V.2
Sutherland, B.M.3
-
13
-
-
6944248997
-
Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells
-
Georgakilas, A.G., Bennett, P.V., Wilson, D.M. III, and Sutherland, B.M. 2004. Processing of bistranded abasic DNA clusters in gamma-irradiated human hematopoietic cells. Nucleic Acids Res. 32:5609-5620.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5609-5620
-
-
Georgakilas, A.G.1
Bennett, P.V.2
Wilson III, D.M.3
Sutherland, B.M.4
-
14
-
-
33846841032
-
Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells
-
Gollapalle, E., Wong, R., Adetolu, R., Tsao, D., Francisco, D., Sigounas, G., and Georgakilas, A.G. 2007. Detection of oxidative clustered DNA lesions in X-irradiated mouse skin tissues and human MCF-7 breast cancer cells. Radiat. Res. 167:207-216.
-
(2007)
Radiat. Res.
, vol.167
, pp. 207-216
-
-
Gollapalle, E.1
Wong, R.2
Adetolu, R.3
Tsao, D.4
Francisco, D.5
Sigounas, G.6
Georgakilas, A.G.7
-
15
-
-
0027976408
-
Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA
-
Goodhead, D.T. 1994. Initial events in the cellular effects of ionizing radiations: Clustered damage in DNA. Int. J. Radiat. Biol. 65:7-17.
-
(1994)
Int. J. Radiat. Biol.
, vol.65
, pp. 7-17
-
-
Goodhead, D.T.1
-
16
-
-
44349188585
-
Formation of clustered DNA damage after high-LET irradiation: A review
-
Hada, M. and Georgakilas, A.G. 2008. Formation of clustered DNA damage after high-LET irradiation: A review. J. Radiat. Res. 49:203-210.
-
(2008)
J. Radiat. Res.
, vol.49
, pp. 203-210
-
-
Hada, M.1
Georgakilas, A.G.2
-
17
-
-
0032788298
-
In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites
-
Harrison, L., Hatahet, Z., and Wallace, S. 1999. In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. J. Mol. Biol. 290:667-684.
-
(1999)
J. Mol. Biol.
, vol.290
, pp. 667-684
-
-
Harrison, L.1
Hatahet, Z.2
Wallace, S.3
-
18
-
-
38449111403
-
Detection of complex DNA damage in γ-irradiated acute lymphoblastic leukemia pre-B NALM-6 cells
-
Holt, S.M. and Georgakilas, A.G. 2007. Detection of complex DNA damage in γ-irradiated acute lymphoblastic leukemia pre-B NALM-6 cells. Radiat. Res. 168:527-534.
-
(2007)
Radiat. Res.
, vol.168
, pp. 527-534
-
-
Holt, S.M.1
Georgakilas, A.G.2
-
19
-
-
0038352053
-
Radical causes of cancer
-
Hussain, S.P., Hofseth, L.J., and Harris, C.C. 2003. Radical causes of cancer. Nat. Rev. Cancer 3:276-285.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 276-285
-
-
Hussain, S.P.1
Hofseth, L.J.2
Harris, C.C.3
-
20
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M.B. and Bartek, J. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
21
-
-
3042631024
-
Gene regulation and DNA damage in the aging human brain
-
Lu, T., Pan, Y., Kao, S.Y., Li, C., Kohane, I., Chan, J., and Yankner, B.A. 2004. Gene regulation and DNA damage in the aging human brain. Nature 429:883-891.
-
(2004)
Nature
, vol.429
, pp. 883-891
-
-
Lu, T.1
Pan, Y.2
Kao, S.Y.3
Li, C.4
Kohane, I.5
Chan, J.6
Yankner, B.A.7
-
22
-
-
0035818408
-
Oligonucleotides with bistranded abasic sites interfere with substrate binding and catalysis by human apurinic/apyrimidinic endonuclease
-
McKenzie, A.A. and Strauss, P.R. 2001. Oligonucleotides with bistranded abasic sites interfere with substrate binding and catalysis by human apurinic/apyrimidinic endonuclease. Biochemistry 40:13254-13261.
-
(2001)
Biochemistry
, vol.40
, pp. 13254-13261
-
-
McKenzie, A.A.1
Strauss, P.R.2
-
23
-
-
0034753336
-
Computational approach for determing the spectrum of DNA damage induced by ionizing radiation
-
Nikjoo, H., O'Neill, P., Wilson, E.W., and Goodhead, D. 2001. Computational approach for determing the spectrum of DNA damage induced by ionizing radiation. Radiat. Res. 156:577-583.
-
(2001)
Radiat. Res.
, vol.156
, pp. 577-583
-
-
Nikjoo, H.1
O'Neill, P.2
Wilson, E.W.3
Goodhead, D.4
-
24
-
-
0027429286
-
Detection of DNA double-strand breaks through the cell cycle after exposure to X-rays, bleomycin, etoposide and 125IdUrd
-
Olive, P.L. and Banath, J.P. 1993. Detection of DNA double-strand breaks through the cell cycle after exposure to X-rays, bleomycin, etoposide and 125IdUrd. Int. J. Rad. Biol. 64:349-358.
-
(1993)
Int. J. Rad. Biol.
, vol.64
, pp. 349-358
-
-
Olive, P.L.1
Banath, J.P.2
-
25
-
-
34250654965
-
The comet assay: A method to measure DNA damage in individual cells
-
Olive, P.L. and Banath, J.P. 2006. The comet assay: A method to measure DNA damage in individual cells. Nat. Protoc. 1:23-29.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 23-29
-
-
Olive, P.L.1
Banath, J.P.2
-
26
-
-
0025270234
-
Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet", assay
-
Olive, P.L., Banáth, J.P., and Durand, R.E. 1990. Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay. Radiat. Res. 122:86-94.
-
(1990)
Radiat. Res.
, vol.122
, pp. 86-94
-
-
Olive, P.L.1
Banáth, J.P.2
Durand, R.E.3
-
27
-
-
0021193203
-
Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells
-
Ostling, O. and Johanson, K.J. 1984. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123:291-298.
-
(1984)
Biochem. Biophys. Res. Commun.
, vol.123
, pp. 291-298
-
-
Ostling, O.1
Johanson, K.J.2
-
28
-
-
0032960559
-
Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: Comparison between the HPLC-EC and comet assays
-
Pouget, J.-P., Ravanat, J.-L., Douki, T., Richard, M.-J., and Cadet, J. 1999. Measurement of DNA base damage in cells exposed to low doses of gamma-radiation: Comparison between the HPLC-EC and comet assays. Int. J. Radiat. Biol. 75:51-58.
-
(1999)
Int. J. Radiat. Biol.
, vol.75
, pp. 51-58
-
-
Pouget, J.-P.1
Ravanat, J.-L.2
Douki, T.3
Richard, M.-J.4
Cadet, J.5
-
29
-
-
0036249832
-
Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles
-
Pouget, J.P., Frelon, S., Ravanat, J.L., Testard, I., Odin, F., and Cadet, J. 2002. Formation of modified DNA bases in cells exposed either to gamma radiation or to high-LET particles. Radiat. Res. 157:589-595.
-
(2002)
Radiat. Res.
, vol.157
, pp. 589-595
-
-
Pouget, J.P.1
Frelon, S.2
Ravanat, J.L.3
Testard, I.4
Odin, F.5
Cadet, J.6
-
30
-
-
0023919963
-
A simple technique for quantitation of low levels of DNA damage in individual cells
-
Singh, N.P., McCoy, M.T., Tice, R.R., and Schneider, E.L. 1998. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 175:184-191.
-
(1998)
Exp. Cell Res.
, vol.175
, pp. 184-191
-
-
Singh, N.P.1
McCoy, M.T.2
Tice, R.R.3
Schneider, E.L.4
-
31
-
-
0034602643
-
DNA damage clusters induced by ionizing radiation in isolated DNA and in human cells
-
Sutherland, B., Bennett, P.V., Sidorkina, O., and Laval, J. 2000a. DNA damage clusters induced by ionizing radiation in isolated DNA and in human cells. Proc. Natl. Acad. Sci. U.S.A. 97:103-108.
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 103-108
-
-
Sutherland, B.1
Bennett, P.V.2
Sidorkina, O.3
Laval, J.4
-
32
-
-
0034636776
-
Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidized bases and strand breaks
-
Sutherland, B.M., Bennett, P.V., Sidorkina, O., and Laval, J. 2000b. Clustered damages and total lesions induced in DNA by ionizing radiation: Oxidized bases and strand breaks. Biochemistry 39:8026-8031.
-
(2000)
Biochemistry
, vol.39
, pp. 8026-8031
-
-
Sutherland, B.M.1
Bennett, P.V.2
Sidorkina, O.3
Laval, J.4
-
33
-
-
0345016976
-
Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis
-
Sutherland, B.M., Georgakilas, A.G., Bennett, P.V., Laval, J., and Sutherland, J.C. 2003. Quantifying clustered DNA damage induction and repair by gel electrophoresis, electronic imaging and number average length analysis. Mutat. Res. 531:93-107.
-
(2003)
Mutat. Res.
, vol.531
, pp. 93-107
-
-
Sutherland, B.M.1
Georgakilas, A.G.2
Bennett, P.V.3
Laval, J.4
Sutherland, J.C.5
-
34
-
-
18344373662
-
Radiosensitivity of lymphoblastoid cell lines with a heterozygous BRCA1 mutation is not detected by the comet assay and pulsed field gel electrophoresis
-
Trenz, K., Schutz, P., and Speit, G. 2005. Radiosensitivity of lymphoblastoid cell lines with a heterozygous BRCA1 mutation is not detected by the comet assay and pulsed field gel electrophoresis. Mutagenesis 20:131-137.
-
(2005)
Mutagenesis
, vol.20
, pp. 131-137
-
-
Trenz, K.1
Schutz, P.2
Speit, G.3
-
36
-
-
0033868497
-
Diversity of peripheral blood mononuclear cells as revealed by a novel multiple microgel comet assay
-
Visvardis, E.E., Haveles, K.S., Pataryas, T.A., Margaritis, L.H., Sophianopoulou, V., and Sideris, E.G. 2000. Diversity of peripheral blood mononuclear cells as revealed by a novel multiple microgel comet assay. Environ. Molec. Mutagen. 36:32-39.
-
(2000)
Environ. Molec. Mutagen.
, vol.36
, pp. 32-39
-
-
Visvardis, E.E.1
Haveles, K.S.2
Pataryas, T.A.3
Margaritis, L.H.4
Sophianopoulou, V.5
Sideris, E.G.6
-
37
-
-
0027973491
-
The complexity of DNA damage: Relevance to biological consequences
-
Ward, J.F. 1994. The complexity of DNA damage: Relevance to biological consequences. Int. J. Radiat. Biol. 66:427-432.
-
(1994)
Int. J. Radiat. Biol.
, vol.66
, pp. 427-432
-
-
Ward, J.F.1
-
38
-
-
4444325894
-
Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks
-
Yang, N., Galick, H., and Wallace, S.S. 2004. Attempted base excision repair of ionizing radiation damage in human lymphoblastoid cells produces lethal and mutagenic double strand breaks. DNA Repair 3:1323-1334.
-
(2004)
DNA Repair
, vol.3
, pp. 1323-1334
-
-
Yang, N.1
Galick, H.2
Wallace, S.S.3
-
39
-
-
29244473835
-
Base excision repair by hNTH1 and hOGG1: A two edged sword in the processing of DNA damage in gamma-irradiated human cells
-
Yang, N., Chaudhry, M.A., and Wallace, S.S. 2006. Base excision repair by hNTH1 and hOGG1: A two edged sword in the processing of DNA damage in gamma-irradiated human cells. DNA Repair 5:43-51.
-
(2006)
DNA Repair
, vol.5
, pp. 43-51
-
-
Yang, N.1
Chaudhry, M.A.2
Wallace, S.S.3
|