Cyclic nucleotide-regulated proliferation and differentiation vary in human hematopoietic progenitor cells derived from healthy persons, tumor patients, and chronic myelocytic leukemia patients

Stem Cells and Development

Volumn 17, Issue 1, 2008, Pages 81-91

  Kobsar, Anna ^a   Heeg, Sonja ^a   Krohne, Katharina ^a   Opitz, Andreas ^a   Walter, Ulrich ^a   Böck, Markus ^a   Gambaryan, Stepan ^a,b   Eigenthaler, Martin ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; CYCLIC NUCLEOTIDE; IMATINIB; PROTEIN SUBUNIT;

ARTICLE; CANCER PATIENT; CELL DIFFERENTIATION; CELL ISOLATION; CELL LINEAGE; CELL PROLIFERATION; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; GRANULOCYTE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LEUKAPHERESIS; MEDULLOBLASTOMA; MEGAKARYOCYTE; MULTIPLE MYELOMA; PRIORITY JOURNAL; SEMINOMA;

CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC GMP-DEPENDENT PROTEIN KINASES; HEMATOPOIETIC STEM CELLS; HUMANS; LEUKAPHERESIS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MEGAKARYOCYTES; NEOPLASMS; NUCLEOTIDES, CYCLIC;

EID: 39449136774     PISSN: 15473287     EISSN: None     Source Type: Journal    
DOI: 10.1089/scd.2007.0060     Document Type: Article

References (43)

1. Pilz RB and DE Casteel. (2003). Regulation of gene expression by cyclic GMP. Circ Res 93:1034-1046.
2. Mujoo K, JS Krumenacker, Y Wada and F. Murad. (2006). Differential expression of nitric oxide signaling components in undifferentiated and differentiated human embryonic stem cells. Stem Cells Dev 15:779-787.
3. To LB, DN Haylock, PJ Simmons and CA Juttner. (1997). The biology and clinical uses of blood stem cells. Blood 89:2233-2258.
4. Piccoli C, R Ria, R Scrima, O Cela, A D'Aprile, D Boffoli, F Falzetti, A Tabilio and N Capitanio. (2005). Characterization of mitochondrial and extramitochondrial oxygen consuming reactions in human hematopoietic stem cells. Novel evidence of the occurrence of NAD(P)H oxidase activity. J Biol Chem 280:26467-26476.
5. Schattner M, RG Pozner, I Engelberger, A Gorostizaga, N Maugeri, R Gomez, A Pasqualini, O Torres and MA Lazzari. (2001). Effect of nitric oxide on megakaryocyte growth induced by thrombopoietin. J Lab Clin Med 137:261-269.
6. Battinelli E, SR Willoughby, T Foxall, CR Valeri and J Loscalzo. (2001). Induction of platelet formation from megakaryocytoid cells by nitric oxide. Proc Natl Acad Sci USA 98:14458-14463.
7. Shami PJ and JB Weinberg. (1996). Differential effects of nitric oxide on erythroid and myeloid colony growth from CD34+ human bone marrow cells. Blood 87:977-982.
8. Negrotto S, N Pacienza, LP D'Atri, RG Pozner, E Malaver, O Torres, MA Lazzari, RM Gomez and M Schattner. (2006). Activation of cyclic AMP pathway prevents CD34(+) cell apoptosis. Exp Hematol 34:1420-1428.
9. Pozner RG, S Negrotto, LP D'Atri, ML Kotler, MA Lazzari, RM Gomez and M Schattner. (2005). Prostacyclin prevents nitric oxide-induced megakaryocyte apoptosis. Br J Pharmacol 145:283-292.
10. Hendrie PC and HE Broxmeyer. (1994). Myeloid cell proliferation stimulated by Steel factor is pertussis toxin sensitive and enhanced by cholera toxin. Int J Immunopharmacol 16:547-560.
11. Lee AW.(1999). Synergistic activation of mitogen-activated protein kinase by cyclic AMP and myeloid growth factors opposes cyclic AMP's growth-inhibitory effects. Blood 93:537-553.
12. Eigenthaler M, C Nolte, M Halbrugge and U Walter. (1992). Concentration and regulation of cyclic nucleotides, cyclic-nucleotide-dependent protein kinases and one of their major substrates in human platelets. Estimating the rate of cAMP-regulated and cGMP regulated protein phosphorylation in intact cells. Eur J Biochem 205:471-481.
13. Smolenski A, C Bachmann, K Reinhard, P Honig-Liedl, T Jarchau, H Hoschuetzky and U Walter. (1998). Analysis and regulation of vasodilatorstimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody. J Biol Chem 273:20029-20035.
14. LaIuppa JA, ET Papoutsakis and WM Miller. (1997). Evaluation of cytokines for expansion of the megakaryocyte and granulocyte lineages. Stem Cells 15:198-206.
15. Butt E, C Nolte, S Schulz, J Beltman, JA Beavo, B Jastorff and U Walter. (1992). Analysis of the functional role of cGMP-dependent protein kinase in intact human platelets using a specific activator 8-parachlorophenylthio-cGMP. Biochem Pharmacol 43:2591-2600.
16. Chavez-Gonzalez A, M Ayala-Sanchez, E Sanchez-Valle, E Ruiz-Sanchez, RM Arana-Trejo, J Vela-Ojeda and H Mayani. (2006). Functional integrity in vitro of hematopoietic progenitor cells from patients with chronic myeloid leukemia that have achieved hematological remission after different therapeutic procedures. Leuk Res 30:286-295.
17. Bhatia R, HA Munthe, AD Williams, F Zhang, SJ Forman and ML Slovak. (2000). Chronic myelogenous leukemia primitive hematopoietic progenitors demonstrate increased sensitivity to growth factor-induced proliferation and maturation. Exp Hematol 28:1401-1412.
18. Moore S, DN Haylock, JP Levesque, LA McDiarmid, LM Samels, LB To, PJ Simmons and TP Hughes. (1998) Stem cell factor as a single agent induces selective proliferation of the Philadelphia chromosome positive fraction of chronic myeloid leukemia CD34(+) cells. Blood 92:2461-2470.
19. Kramer A, H Loffler, J Bergmann, A Hochhaus and R Hehlmann. (2001). Proliferating status of peripheral blood progenitor cells from patients with BCR/ABL-positive chronic myelogenous leukemia. Leukemia 15:62-68.
20. Bedi A, BA Zehnbauer, JP Barber, SJ Sharkis and RJ Jones. (1994). Inhibition of apoptosis by BCR-ABL in chronic myeloid leukemia. Blood 83:2038-2044.
21. McGahon A, R Bissonnette, M Schmitt, KM Cotter, DR Green and TG Cotter. (1994). BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death. Blood 83:1179-1187.
22. Coppola S, L Narciso, T Feccia, D Bonci, L Calabro, O Morsilli, M Gabbianelli, R De Maria, U Testa and C Peschle. (2006). Enforced expression of KDR receptor promotes proliferation, survival and megakaryocytic differentiation of TF1 progenitor cell line. Cell Death Differ 13:61-74.
23. Gerber HP and N Ferrara. (2003). The role of VEGF in normal and neoplastic hematopoiesis. J Mol Med 81:20-31.
24. Larrivee B, DR Lane, I Pollet, PL Olive, RK Humphries and A Karsan. (2003). Vascular endothelial growth factor receptor-2 induces survival of hematopoietic progenitor cells. J Biol Che; 278:22006-22013.
25. He ZX, SL Huang, QF Zhou and SN Li. (2004). [Generation of CD34+/Sca-1+ cells from mouse embryonic stem cells with two-step differentiation in vitro]. Zhonghua Er Ke Za Zhi 42:830-834.
26. Kraft A, K Weindel, A Ochs, C Marth, J Zmija, P Schumacher, C Unger, D Marme and G Gastl. (1999). Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease. Cancer 85:178-187.
27. Oehler MK and H Caffier. (1999). Diagnostic value of serum VEGF in women with ovarian tumors. Anticancer Res 19:2519-2522.
28. Komorowski J, J Jankewicz and H Stepien. (2000). Vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and soluble interleukin-2 receptor (sIL-2R) concentrations in peripheral blood as markers of pituitary tumours. Cytobios 101:151-159.
29. Gunsilius E and G Gastl. (1999). Platelets and VEGF blood levels in cancer patients. Br J Cancer 81:185-186.
30. Liu P, J Li, ZC Han, H Lu, Y Wang, B Xu and Z Peng. (2005). Elevated plasma levels of vascular endothelial growth factor is associated with marked splenomegaly in chronic myeloid leukemia. Leuk Lymphoma 46: 1761-1764.
31. Ratajczak MZ, J Ratajczak, B Machalinski, M Majka, W Marlicz, A Carter, Z Pietrzkowski and AM Gewirtz. (1998). Role of vascular endothelial growth factor (VEGF) and placenta-derived growth factor (PlGF) in regulating human haemopoietic cell growth. Br J Haematol 103: 969-979.
32. Schmidt HH, SM Lohmann and U Walter. (1993). The nitric oxide and cGMP signal transduction system: regulation and mechanism of action. Biochim Biophys Acta 1178:153-175.
33. Smolenski A, AM Burkhardt, M Eigenthaler, E Butt, S Gambaryan, SM Lohmann and U Walter. (1998). Functional analysis of cGMPdependent protein kinases I and II as mediators of NO/cGMP effects. Naunyn Schmiedebergs Arch Pharmacol 358:134-139.
34. Cornwell TL, GA Soff, AE Traynor and TM Lincoln. (1994). Regulation of the expression of cyclic GMP-dependent protein kinase by cell density in vascular smooth muscle cells. J Vasc Res 31:330-337.
35. Fischer TA, A Palmetshofer, S Gambaryan, E Butt, C Jassoy, U Walter, S Sopper and SM Lohmann. (2001). Activation of cGMP-dependent protein kinase I beta inhibits interleukin 2 release and proliferation of T cell receptor stimulated human peripheral T cells. J Biol Chem 276:5967-5974.
36. Battinelli E and J Loscalzo. (2000). Nitric oxide induces apoptosis in megakaryocytic cell lines. Blood 95:3451-3459.
37. Maciejewski JP, C Selleri, T Sato, HJ Cho, LK Keefer, CF Nathan and NS Young. (1995). Nitric oxide suppression of human hematopoiesis in vitro. Contribution to inhibitory action of interferon-gamma and tumor necrosis factor-alpha. J Clin Invest 96:1085-1092.
38. Magrinat G, SN Mason, PJ Shami and JB Weinberg. (1992). Nitric oxide modulation of human leukemia cell differentiation and gene expression. Blood 80:1880-1884.
39. Shami PJ, JO Moore, JP Gockerman, JW Hathorn, MA Misukonis and JB Weinberg. (1995). Nitric oxide modulation of the growth and differentiation of freshly isolated acute nonlymphocytic leukemia cells. Leuk Res 19:527-533.
40. Vittet D, C Duperray and C Chevillard. (1995). Cyclic-AMP inhibits cell growth and negatively interacts with platelet membrane glycoprotein expression on the Dami human megakaryoblastic cell line. J Cell Physiol 163:645-655.
41. Bender AT, CL Ostenson, EH Wang and JA Beavo. (2005). Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation. Proc Natl Acad Sci USA 102:497-502.
42. Pan W, LD Quarles, LH Song, YH Yu, C Jiao, HB Tang, CH Jiang, HW Deng, YJ Li, HH Zhou and ZS Xiao. (2005). Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture. J Cell Biochem 94: 307-316.
43. Steinbrink K, L Paragnik, H Jonuleit, T Tuting, J Knop and AH Enk. (2000). Induction of dendritic cell maturation and modulation of dendritic cell-induced immune responses by prostaglandins. Arch Dermatol Res 292:437-445.