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Volumn 29, Issue 16, 2011, Pages 3008-3020

A comparative analysis of HIV-specific mucosal/systemic T cell immunity and avidity following rDNA/rFPV and poxvirus-poxvirus prime boost immunisations

Author keywords

DNA vaccines; Mucosal immunity; Poxvirus vectors; T cell avidity

Indexed keywords

DNA VACCINE; FOWLPOX VIRUS VECTOR; GAG PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS 1 VECTOR; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; LIPOFECTAMINE; PLASMID DNA; RECOMBINANT DNA; UNCLASSIFIED DRUG; VACCINIA VIRUS VECTOR; VIRUS DNA; VIRUS VECTOR;

EID: 79953166393     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2011.01.106     Document Type: Article
Times cited : (30)

References (54)
  • 1
    • 33646045350 scopus 로고    scopus 로고
    • A randomised, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1
    • Kelleher A.D., Puls R.L., Bebbington M., Boyle D., Ffrench R., Kent S.J., et al. A randomised, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1. AIDS 2006, 20(2):294-297.
    • (2006) AIDS , vol.20 , Issue.2 , pp. 294-297
    • Kelleher, A.D.1    Puls, R.L.2    Bebbington, M.3    Boyle, D.4    Ffrench, R.5    Kent, S.J.6
  • 2
    • 38749096240 scopus 로고    scopus 로고
    • The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
    • Sekaly R.P. The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?. J Exp Med 2008, 205(1):7-12.
    • (2008) J Exp Med , vol.205 , Issue.1 , pp. 7-12
    • Sekaly, R.P.1
  • 3
    • 17344381593 scopus 로고    scopus 로고
    • HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
    • Kaul R., Plummer F.A., Kimani J., Dong T., Kiama P., Rostron T., et al. HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi. J Immunol 2000, 164:1602-1611.
    • (2000) J Immunol , vol.164 , pp. 1602-1611
    • Kaul, R.1    Plummer, F.A.2    Kimani, J.3    Dong, T.4    Kiama, P.5    Rostron, T.6
  • 4
    • 0037404116 scopus 로고    scopus 로고
    • The role of mucosal immunity in prevention of HIV transmission
    • Kozlowski P.A., Neutra M.R. The role of mucosal immunity in prevention of HIV transmission. Curr Mol Med 2003, 3(3):217-228.
    • (2003) Curr Mol Med , vol.3 , Issue.3 , pp. 217-228
    • Kozlowski, P.A.1    Neutra, M.R.2
  • 5
    • 2342545549 scopus 로고    scopus 로고
    • Mucosal HIV vaccines: where are we now?
    • Stevceva L., Strober W. Mucosal HIV vaccines: where are we now?. Curr HIV Res 2004, 2(1):1-10.
    • (2004) Curr HIV Res , vol.2 , Issue.1 , pp. 1-10
    • Stevceva, L.1    Strober, W.2
  • 6
    • 4344678042 scopus 로고    scopus 로고
    • Mucosal AIDS vaccines: current status and future directions
    • Belyakov I.M., Ahlers J.D., Berzofsky J.A. Mucosal AIDS vaccines: current status and future directions. Expert Rev Vaccines 2004, 3(4 Suppl.):S65-73.
    • (2004) Expert Rev Vaccines , vol.3 , Issue.4 SUPPL.
    • Belyakov, I.M.1    Ahlers, J.D.2    Berzofsky, J.A.3
  • 7
    • 0032540418 scopus 로고    scopus 로고
    • Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection
    • Veazey R.S., DeMaria M., Chalifoux L.V., Shvetz D.E., Pauley D.R., Knight H.L., et al. Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection. Science 1998, 280(5362):427-431.
    • (1998) Science , vol.280 , Issue.5362 , pp. 427-431
    • Veazey, R.S.1    DeMaria, M.2    Chalifoux, L.V.3    Shvetz, D.E.4    Pauley, D.R.5    Knight, H.L.6
  • 8
    • 0035074535 scopus 로고    scopus 로고
    • Vaccination strategies for mucosal immune responses
    • Ogra P.L., Faden H., Welliver R.C. Vaccination strategies for mucosal immune responses. Clin Microbiol Rev 2001, 14(2):430-445.
    • (2001) Clin Microbiol Rev , vol.14 , Issue.2 , pp. 430-445
    • Ogra, P.L.1    Faden, H.2    Welliver, R.C.3
  • 9
    • 0027443053 scopus 로고
    • Fowlpox virus host range restriction: gene expression. DNA replication, and morphogenesis in nonpermissive mammalian cells
    • Somogyi P., Frazier J., Skinner M.A. Fowlpox virus host range restriction: gene expression. DNA replication, and morphogenesis in nonpermissive mammalian cells. Virology 1993, 197(1):439-444.
    • (1993) Virology , vol.197 , Issue.1 , pp. 439-444
    • Somogyi, P.1    Frazier, J.2    Skinner, M.A.3
  • 10
    • 0000283580 scopus 로고
    • Molecular approaches to the control of infectious diseases
    • Brown F, Chanock H, Norrby E, Eds.
    • Leong KH, Ramsay AJ, Morin MJ, Robinson HL, Boyle DB, Ramshaw IA. Molecular approaches to the control of infectious diseases. Vaccine 95 1995;Brown F, Chanock H, Norrby E, Eds.:327-31.
    • (1995) Vaccine , vol.95 , pp. 327-31
    • Leong, K.H.1    Ramsay, A.J.2    Morin, M.J.3    Robinson, H.L.4    Boyle, D.B.5    Ramshaw, I.A.6
  • 11
    • 0031772993 scopus 로고    scopus 로고
    • Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus
    • Kent S.J., Zhao A., Best S.J., Chandler J.D., Boyle D.B., Ramshaw I.A. Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus. J Virol 1998, 72(12):10180-10188.
    • (1998) J Virol , vol.72 , Issue.12 , pp. 10180-10188
    • Kent, S.J.1    Zhao, A.2    Best, S.J.3    Chandler, J.D.4    Boyle, D.B.5    Ramshaw, I.A.6
  • 12
    • 3142615273 scopus 로고    scopus 로고
    • Construction of recombinant fowlpox viruses carrying multiple vaccine antigens and immunomodulatory molecules
    • 8-11
    • Boyle D.B., Anderson M.A., Amos R., Voysey R., Coupar B.E. Construction of recombinant fowlpox viruses carrying multiple vaccine antigens and immunomodulatory molecules. Biotechniques 2004, 37(1):104-106. 8-11.
    • (2004) Biotechniques , vol.37 , Issue.1 , pp. 104-106
    • Boyle, D.B.1    Anderson, M.A.2    Amos, R.3    Voysey, R.4    Coupar, B.E.5
  • 13
    • 0030872511 scopus 로고    scopus 로고
    • Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit
    • Barnett S.W., Rajasekar S., Legg H., Doe B., Fuller D.H., Haynes J.R., et al. Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit. Vaccine 1997, 15(8):869-873.
    • (1997) Vaccine , vol.15 , Issue.8 , pp. 869-873
    • Barnett, S.W.1    Rajasekar, S.2    Legg, H.3    Doe, B.4    Fuller, D.H.5    Haynes, J.R.6
  • 14
    • 0033577255 scopus 로고    scopus 로고
    • A novel vaccine regimen utilizing DNA, vaccinia virus and protein immunizations for HIV-1 envelope presentation
    • Caver T.E., Lockey T.D., Srinivas R.V., Webster R.G., Hurwitz J.L. A novel vaccine regimen utilizing DNA, vaccinia virus and protein immunizations for HIV-1 envelope presentation. Vaccine 1999, 17(11-12):1567-1572.
    • (1999) Vaccine , vol.17 , Issue.11-12 , pp. 1567-1572
    • Caver, T.E.1    Lockey, T.D.2    Srinivas, R.V.3    Webster, R.G.4    Hurwitz, J.L.5
  • 15
    • 0038709309 scopus 로고    scopus 로고
    • Induction of broad and potent anti-human immunodeficiency virus immune responses in rhesus macaques by priming with a DNA vaccine and boosting with protein-adsorbed polylactide coglycolide microparticles
    • Otten G., Schaefer M., Greer C., Calderon-Cacia M., Coit D., Kazzaz J., et al. Induction of broad and potent anti-human immunodeficiency virus immune responses in rhesus macaques by priming with a DNA vaccine and boosting with protein-adsorbed polylactide coglycolide microparticles. J Virol 2003, 77(10):6087-6092.
    • (2003) J Virol , vol.77 , Issue.10 , pp. 6087-6092
    • Otten, G.1    Schaefer, M.2    Greer, C.3    Calderon-Cacia, M.4    Coit, D.5    Kazzaz, J.6
  • 16
    • 11144357988 scopus 로고    scopus 로고
    • Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A
    • Epstein J.E., Charoenvit Y., Kester K.E., Wang R., Newcomer R., Fitzpatrick S., et al. Safety, tolerability, and antibody responses in humans after sequential immunization with a PfCSP DNA vaccine followed by the recombinant protein vaccine RTS,S/AS02A. Vaccine 2004, 22(13-14):1592-1603.
    • (2004) Vaccine , vol.22 , Issue.13-14 , pp. 1592-1603
    • Epstein, J.E.1    Charoenvit, Y.2    Kester, K.E.3    Wang, R.4    Newcomer, R.5    Fitzpatrick, S.6
  • 17
    • 14844320079 scopus 로고    scopus 로고
    • Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy
    • Stambas J., Brown S.A., Gutierrez A., Sealy R., Yue W., Jones B., et al. Long lived multi-isotype anti-HIV antibody responses following a prime-double boost immunization strategy. Vaccine 2005, 23(19):2454-2464.
    • (2005) Vaccine , vol.23 , Issue.19 , pp. 2454-2464
    • Stambas, J.1    Brown, S.A.2    Gutierrez, A.3    Sealy, R.4    Yue, W.5    Jones, B.6
  • 18
    • 8644266843 scopus 로고    scopus 로고
    • Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFNgamma or IL-12
    • Dale C.J., De Rose R., Wilson K.M., Croom H.A., Thomson S., Coupar B.E., et al. Evaluation in macaques of HIV-1 DNA vaccines containing primate CpG motifs and fowlpoxvirus vaccines co-expressing IFNgamma or IL-12. Vaccine 2004, 23(2):188-197.
    • (2004) Vaccine , vol.23 , Issue.2 , pp. 188-197
    • Dale, C.J.1    De Rose, R.2    Wilson, K.M.3    Croom, H.A.4    Thomson, S.5    Coupar, B.E.6
  • 19
    • 11144355460 scopus 로고    scopus 로고
    • A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans
    • Mwau M., Cebere I., Sutton J., Chikoti P., Winstone N., Wee E.G., et al. A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans. J Gen Virol 2004, 85(Pt 4):911-919.
    • (2004) J Gen Virol , vol.85 , Issue.PART 4 , pp. 911-919
    • Mwau, M.1    Cebere, I.2    Sutton, J.3    Chikoti, P.4    Winstone, N.5    Wee, E.G.6
  • 20
    • 58149204280 scopus 로고    scopus 로고
    • Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers
    • Guimaraes-Walker A., Mackie N., McCormack S., Hanke T., Schmidt C., Gilmour J., et al. Lessons from IAVI-006, a phase I clinical trial to evaluate the safety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a prime-boost strategy to induce HIV-1 specific T-cell responses in healthy volunteers. Vaccine 2008, 26(51):6671-6677.
    • (2008) Vaccine , vol.26 , Issue.51 , pp. 6671-6677
    • Guimaraes-Walker, A.1    Mackie, N.2    McCormack, S.3    Hanke, T.4    Schmidt, C.5    Gilmour, J.6
  • 21
    • 44749088148 scopus 로고    scopus 로고
    • EV02: a phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone
    • McCormack S., Stohr W., Barber T., Bart P.A., Harari A., Moog C., et al. EV02: a phase I trial to compare the safety and immunogenicity of HIV DNA-C prime-NYVAC-C boost to NYVAC-C alone. Vaccine 2008, 26(25):3162-3174.
    • (2008) Vaccine , vol.26 , Issue.25 , pp. 3162-3174
    • McCormack, S.1    Stohr, W.2    Barber, T.3    Bart, P.A.4    Harari, A.5    Moog, C.6
  • 22
    • 0029813121 scopus 로고    scopus 로고
    • Role of antigen CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL
    • Alexander-Miller M.A., Leggatt G.R., Sarin A., Berzofsky J.A. Role of antigen CD8, and cytotoxic T lymphocyte (CTL) avidity in high dose antigen induction of apoptosis of effector CTL. J Exp Med 1996, 184(2):485-492.
    • (1996) J Exp Med , vol.184 , Issue.2 , pp. 485-492
    • Alexander-Miller, M.A.1    Leggatt, G.R.2    Sarin, A.3    Berzofsky, J.A.4
  • 23
    • 2142815852 scopus 로고    scopus 로고
    • Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity
    • La Gruta N.L., Turner S.J., Doherty P.C. Hierarchies in cytokine expression profiles for acute and resolving influenza virus-specific CD8+ T cell responses: correlation of cytokine profile and TCR avidity. J Immunol 2004, 172(9):5553-5560.
    • (2004) J Immunol , vol.172 , Issue.9 , pp. 5553-5560
    • La Gruta, N.L.1    Turner, S.J.2    Doherty, P.C.3
  • 24
    • 23844532213 scopus 로고    scopus 로고
    • Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIV(SF162P3)
    • Kent S.J., Dale C.J., Ranasinghe C., Stratov I., De Rose R., Chea S., et al. Mucosally-administered human-simian immunodeficiency virus DNA and fowlpoxvirus-based recombinant vaccines reduce acute phase viral replication in macaques following vaginal challenge with CCR5-tropic SHIV(SF162P3). Vaccine 2005, 23:5009-5021.
    • (2005) Vaccine , vol.23 , pp. 5009-5021
    • Kent, S.J.1    Dale, C.J.2    Ranasinghe, C.3    Stratov, I.4    De Rose, R.5    Chea, S.6
  • 25
    • 33746829947 scopus 로고    scopus 로고
    • Evaluation of fowlpox-vaccinia virus prime-boost vaccine strategies for high-level mucosal and systemic Iimmunity against HIV-1
    • Ranasinghe C., Medveczky J.C., Woltring D., Gao K., Thomson S., Coupar B.E.H., et al. Evaluation of fowlpox-vaccinia virus prime-boost vaccine strategies for high-level mucosal and systemic Iimmunity against HIV-1. Vaccine 2006, 24:5881-5895.
    • (2006) Vaccine , vol.24 , pp. 5881-5895
    • Ranasinghe, C.1    Medveczky, J.C.2    Woltring, D.3    Gao, K.4    Thomson, S.5    Coupar, B.E.H.6
  • 26
    • 33846924548 scopus 로고    scopus 로고
    • Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles
    • Ranasinghe C., Turner S.J., McArthur C., Sutherland D.B., Kim J.H., Doherty P.C., et al. Mucosal HIV-1 pox virus prime-boost immunization induces high-avidity CD8+ T cells with regime-dependent cytokine/granzyme B profiles. J Immunol 2007, 178(4):2370-2379.
    • (2007) J Immunol , vol.178 , Issue.4 , pp. 2370-2379
    • Ranasinghe, C.1    Turner, S.J.2    McArthur, C.3    Sutherland, D.B.4    Kim, J.H.5    Doherty, P.C.6
  • 27
    • 0021798008 scopus 로고
    • Multiple-cloning-site plasmids for the rapid construction of recombinant poxviruses
    • Boyle D.B., Coupar B.E., Both G.W. Multiple-cloning-site plasmids for the rapid construction of recombinant poxviruses. Gene 1985, 35:169-177.
    • (1985) Gene , vol.35 , pp. 169-177
    • Boyle, D.B.1    Coupar, B.E.2    Both, G.W.3
  • 29
    • 70350565493 scopus 로고    scopus 로고
    • Narrowed TCR diversity for immunised mice challenged with recombinant influenza A-HIV Env(311-320) virus
    • Cukalac T., Moffat J.M., Venturi V., Davenport M.P., Doherty P.C., Turner S.J., et al. Narrowed TCR diversity for immunised mice challenged with recombinant influenza A-HIV Env(311-320) virus. Vaccine 2009, 27(48):6755-6761.
    • (2009) Vaccine , vol.27 , Issue.48 , pp. 6755-6761
    • Cukalac, T.1    Moffat, J.M.2    Venturi, V.3    Davenport, M.P.4    Doherty, P.C.5    Turner, S.J.6
  • 30
    • 67650917877 scopus 로고    scopus 로고
    • Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques
    • Sexton A., De Rose R., Reece J.C., Alcantara S., Loh L., Moffat J.M., et al. Evaluation of recombinant influenza virus-simian immunodeficiency virus vaccines in macaques. J Virol 2009, 83(15):7619-7628.
    • (2009) J Virol , vol.83 , Issue.15 , pp. 7619-7628
    • Sexton, A.1    De Rose, R.2    Reece, J.C.3    Alcantara, S.4    Loh, L.5    Moffat, J.M.6
  • 31
    • 69249155108 scopus 로고    scopus 로고
    • Immunisation route-dependent expression of IL-4/IL-13 can modulate HIV-specific CD8(+) CTL avidity
    • Ranasinghe C., Ramshaw I.A. Immunisation route-dependent expression of IL-4/IL-13 can modulate HIV-specific CD8(+) CTL avidity. Eur J Immunol 2009, 39(7):1819-1830.
    • (2009) Eur J Immunol , vol.39 , Issue.7 , pp. 1819-1830
    • Ranasinghe, C.1    Ramshaw, I.A.2
  • 32
    • 33748092412 scopus 로고    scopus 로고
    • Dose-response relationship of DNA and recombinant fowlpox virus prime-boost HIV vaccines: implications for future trials
    • De Rose R., Sullivan M.T., Dale C.J., Kelleher A.D., Emery S., Cooper D.A., et al. Dose-response relationship of DNA and recombinant fowlpox virus prime-boost HIV vaccines: implications for future trials. Hum Vaccine 2006, 2(3):134-136.
    • (2006) Hum Vaccine , vol.2 , Issue.3 , pp. 134-136
    • De Rose, R.1    Sullivan, M.T.2    Dale, C.J.3    Kelleher, A.D.4    Emery, S.5    Cooper, D.A.6
  • 33
    • 0035815437 scopus 로고    scopus 로고
    • Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine
    • Amara R.R., Villinger F., Altman J.D., Lydy S.L., O'Neil S.P., Staprans S.I., et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 2001, 292(5514):69-74.
    • (2001) Science , vol.292 , Issue.5514 , pp. 69-74
    • Amara, R.R.1    Villinger, F.2    Altman, J.D.3    Lydy, S.L.4    O'Neil, S.P.5    Staprans, S.I.6
  • 34
    • 17144465337 scopus 로고    scopus 로고
    • Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239
    • Horton H., Vogel T.U., Carter D.K., Vielhuber K., Fuller D.H., Shipley T., et al. Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression following challenge with pathogenic SIVmac239. J Virol 2002, 76(14):7187-7202.
    • (2002) J Virol , vol.76 , Issue.14 , pp. 7187-7202
    • Horton, H.1    Vogel, T.U.2    Carter, D.K.3    Vielhuber, K.4    Fuller, D.H.5    Shipley, T.6
  • 35
    • 29244455769 scopus 로고    scopus 로고
    • Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag
    • Casimiro D.R., Wang F., Schleif W.A., Liang X., Zhang Z.Q., Tobery T.W., et al. Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag. J Virol 2005, 79(24):15547-15555.
    • (2005) J Virol , vol.79 , Issue.24 , pp. 15547-15555
    • Casimiro, D.R.1    Wang, F.2    Schleif, W.A.3    Liang, X.4    Zhang, Z.Q.5    Tobery, T.W.6
  • 36
    • 33845728487 scopus 로고    scopus 로고
    • Comparative efficacy of subtype AE simian-human immunodeficiency virus priming and boosting vaccines in pigtail macaques
    • De Rose R., Batten C.J., Smith M.Z., Fernandez C.S., Peut V., Thomson S., et al. Comparative efficacy of subtype AE simian-human immunodeficiency virus priming and boosting vaccines in pigtail macaques. J Virol 2007, 81(1):292-300.
    • (2007) J Virol , vol.81 , Issue.1 , pp. 292-300
    • De Rose, R.1    Batten, C.J.2    Smith, M.Z.3    Fernandez, C.S.4    Peut, V.5    Thomson, S.6
  • 37
    • 0032402228 scopus 로고    scopus 로고
    • Nasal immunisation of nonhuman primates with simian immunodeficiency virus p55gag and cholera toxin adjuvant induces Th1/Th2 help for virus-specific immune responses in reproductive tissues
    • Imaoka K., Miller C.J., Kubota M., McChesney M.B., Lohman B., Yamamoto M., et al. Nasal immunisation of nonhuman primates with simian immunodeficiency virus p55gag and cholera toxin adjuvant induces Th1/Th2 help for virus-specific immune responses in reproductive tissues. J Immunol 1998, 161:5952-5958.
    • (1998) J Immunol , vol.161 , pp. 5952-5958
    • Imaoka, K.1    Miller, C.J.2    Kubota, M.3    McChesney, M.B.4    Lohman, B.5    Yamamoto, M.6
  • 38
    • 33747809289 scopus 로고    scopus 로고
    • A second generation of double mutant cholera toxin adjuvants: enhanced immunity without intracellular trafficking
    • Hagiwara Y., Kawamura Y.I., Kataoka K., Rahima B., Jackson R.J., Komase K., et al. A second generation of double mutant cholera toxin adjuvants: enhanced immunity without intracellular trafficking. J Immunol 2006, 177(5):3045-3054.
    • (2006) J Immunol , vol.177 , Issue.5 , pp. 3045-3054
    • Hagiwara, Y.1    Kawamura, Y.I.2    Kataoka, K.3    Rahima, B.4    Jackson, R.J.5    Komase, K.6
  • 39
    • 27644592654 scopus 로고    scopus 로고
    • Recombinant poxviruses and mucosal vaccine vectors
    • Gherardi M.M., Esteban M. Recombinant poxviruses and mucosal vaccine vectors. J Gen Virol 2005, 86:2925-2936.
    • (2005) J Gen Virol , vol.86 , pp. 2925-2936
    • Gherardi, M.M.1    Esteban, M.2
  • 40
    • 53849088921 scopus 로고    scopus 로고
    • Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization
    • Belyakov I.M., Ahlers J.D., Nabel G.J., Moss B., Berzofsky J.A. Generation of functionally active HIV-1 specific CD8+ CTL in intestinal mucosa following mucosal, systemic or mixed prime-boost immunization. Virology 2008, 381(1):106-115.
    • (2008) Virology , vol.381 , Issue.1 , pp. 106-115
    • Belyakov, I.M.1    Ahlers, J.D.2    Nabel, G.J.3    Moss, B.4    Berzofsky, J.A.5
  • 41
    • 0037547065 scopus 로고    scopus 로고
    • Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration
    • Ramirez J.C., Finke D., Esteban M., Kraehenbuhl J.P., Acha-Orbea H. Tissue distribution of the Ankara strain of vaccinia virus (MVA) after mucosal or systemic administration. Arch Virol 2003, 148(5):827-839.
    • (2003) Arch Virol , vol.148 , Issue.5 , pp. 827-839
    • Ramirez, J.C.1    Finke, D.2    Esteban, M.3    Kraehenbuhl, J.P.4    Acha-Orbea, H.5
  • 42
    • 36549059634 scopus 로고    scopus 로고
    • Mucosal priming with replicative Tiantan vaccinia and systemic boosting with DNA vaccine raised strong mucosal and systemic HIV-specific immune responses
    • Huang X., Liu L., Ren L., Qiu C., Wan Y., Xu J. Mucosal priming with replicative Tiantan vaccinia and systemic boosting with DNA vaccine raised strong mucosal and systemic HIV-specific immune responses. Vaccine 2007, 25(52):8874-8884.
    • (2007) Vaccine , vol.25 , Issue.52 , pp. 8874-8884
    • Huang, X.1    Liu, L.2    Ren, L.3    Qiu, C.4    Wan, Y.5    Xu, J.6
  • 43
    • 41149095963 scopus 로고    scopus 로고
    • Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic
    • Corbett M., Bogers W.M., Heeney J.L., Gerber S., Genin C., Didierlaurent A., et al. Aerosol immunization with NYVAC and MVA vectored vaccines is safe, simple, and immunogenic. Proc Natl Acad Sci USA 2008, 105(6):2046-2051.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.6 , pp. 2046-2051
    • Corbett, M.1    Bogers, W.M.2    Heeney, J.L.3    Gerber, S.4    Genin, C.5    Didierlaurent, A.6
  • 44
    • 61449181174 scopus 로고    scopus 로고
    • Comment on " trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination"
    • [author reply -80]
    • Belyakov I.M., Ahlers J.D. Comment on " trafficking of antigen-specific CD8+ T lymphocytes to mucosal surfaces following intramuscular vaccination" J Immunol 2009, 182(4):1779. [author reply -80].
    • (2009) J Immunol , vol.182 , Issue.4 , pp. 1779
    • Belyakov, I.M.1    Ahlers, J.D.2
  • 45
    • 15844394511 scopus 로고    scopus 로고
    • Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques
    • Lehner T., Wang Y., Cranage M., Bergmeier L.A., Mitchell E., Tao L., et al. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat Med 1996, 2(7):767-775.
    • (1996) Nat Med , vol.2 , Issue.7 , pp. 767-775
    • Lehner, T.1    Wang, Y.2    Cranage, M.3    Bergmeier, L.A.4    Mitchell, E.5    Tao, L.6
  • 46
    • 0037402631 scopus 로고    scopus 로고
    • DNA immunization via intramuscular and intradermal routes using a gene gun provides different magnitudes and durations on immune response
    • Ito K., Shinohara N., Kato S. DNA immunization via intramuscular and intradermal routes using a gene gun provides different magnitudes and durations on immune response. Mol Immunol 2003, 39(14):847-854.
    • (2003) Mol Immunol , vol.39 , Issue.14 , pp. 847-854
    • Ito, K.1    Shinohara, N.2    Kato, S.3
  • 47
    • 11244299387 scopus 로고    scopus 로고
    • High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors
    • Alexander-Miller M.A. High-avidity CD8+ T cells: optimal soldiers in the war against viruses and tumors. Immunol Res 2005, 31(1):13-24.
    • (2005) Immunol Res , vol.31 , Issue.1 , pp. 13-24
    • Alexander-Miller, M.A.1
  • 48
    • 33645748846 scopus 로고    scopus 로고
    • Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa
    • Belyakov I.M., Kuznetsov V.A., Kelsall B., Klinman D., Moniuszko M., Lemon M., et al. Impact of vaccine-induced mucosal high-avidity CD8+ CTLs in delay of AIDS viral dissemination from mucosa. Blood 2006, 107(8):3258-3264.
    • (2006) Blood , vol.107 , Issue.8 , pp. 3258-3264
    • Belyakov, I.M.1    Kuznetsov, V.A.2    Kelsall, B.3    Klinman, D.4    Moniuszko, M.5    Lemon, M.6
  • 49
    • 34548794941 scopus 로고    scopus 로고
    • Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells
    • Kroger C.J., Alexander-Miller M.A. Cutting edge: CD8+ T cell clones possess the potential to differentiate into both high- and low-avidity effector cells. J Immunol 2007, 179(2):748-751.
    • (2007) J Immunol , vol.179 , Issue.2 , pp. 748-751
    • Kroger, C.J.1    Alexander-Miller, M.A.2
  • 50
    • 33646869319 scopus 로고    scopus 로고
    • Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection
    • Duvall M.G., Jaye A., Dong T., Brenchley J.M., Alabi A.S., Jeffries D.J., et al. Maintenance of HIV-specific CD4+ T cell help distinguishes HIV-2 from HIV-1 infection. J Immunol 2006, 176(11):6973-6981.
    • (2006) J Immunol , vol.176 , Issue.11 , pp. 6973-6981
    • Duvall, M.G.1    Jaye, A.2    Dong, T.3    Brenchley, J.M.4    Alabi, A.S.5    Jeffries, D.J.6
  • 51
    • 70149092384 scopus 로고    scopus 로고
    • Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis
    • Aagaard C.S., Hoang T.T., Vingsbo-Lundberg C., Dietrich J., Andersen P. Quality and vaccine efficacy of CD4+ T cell responses directed to dominant and subdominant epitopes in ESAT-6 from Mycobacterium tuberculosis. J Immunol 2009, 183(4):2659-2668.
    • (2009) J Immunol , vol.183 , Issue.4 , pp. 2659-2668
    • Aagaard, C.S.1    Hoang, T.T.2    Vingsbo-Lundberg, C.3    Dietrich, J.4    Andersen, P.5
  • 52
    • 65649150652 scopus 로고    scopus 로고
    • How to design effective vaccines: lessons from an old success story
    • Ahmed N., Gottschalk S. How to design effective vaccines: lessons from an old success story. Expert Rev Vaccines 2009, 8(5):543-546.
    • (2009) Expert Rev Vaccines , vol.8 , Issue.5 , pp. 543-546
    • Ahmed, N.1    Gottschalk, S.2
  • 53
    • 65449126294 scopus 로고    scopus 로고
    • Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control
    • Ferre A.L., Hunt P.W., Critchfield J.W., Young D.H., Morris M.M., Garcia J.C., et al. Mucosal immune responses to HIV-1 in elite controllers: a potential correlate of immune control. Blood 2009, 113(17):3978-3989.
    • (2009) Blood , vol.113 , Issue.17 , pp. 3978-3989
    • Ferre, A.L.1    Hunt, P.W.2    Critchfield, J.W.3    Young, D.H.4    Morris, M.M.5    Garcia, J.C.6
  • 54
    • 36048956469 scopus 로고    scopus 로고
    • Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype
    • Harari A., Cellerai C., Enders F.B., Kostler J., Codarri L., Tapia G., et al. Skewed association of polyfunctional antigen-specific CD8 T cell populations with HLA-B genotype. Proc Natl Acad Sci USA 2007, 104(41):16233-16238.
    • (2007) Proc Natl Acad Sci USA , vol.104 , Issue.41 , pp. 16233-16238
    • Harari, A.1    Cellerai, C.2    Enders, F.B.3    Kostler, J.4    Codarri, L.5    Tapia, G.6


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